erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Zhang RL et al. [Study on interventional methods and the pattern of maternal-fetal transmission of syphilis during pregnancy]. 2007 Zhonghua Fu Chan Ke Za Zhi pmid:17961330
Xia AF [Effect of oculentum erythromycin in the prevention of inflammatory conjunctivitis of neonates]. 1993 Zhonghua Hu Li Za Zhi pmid:8339361
Li X [Combination of commonly used antibiotics in intravenous infusions]. 1991 Zhonghua Hu Li Za Zhi pmid:1889101
Yuan H et al. [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. 2011 Zhonghua Jie He He Hu Xi Za Zhi pmid:22041779
Yin YD et al. [Survey of macrolide resistance in Mycoplasma pneumoniae in adult patients with community-acquired pneumonia in Beijing, China]. 2013 Zhonghua Jie He He Hu Xi Za Zhi pmid:24503430
Huang JQ and Xie CM [The effects of erythromycin on the secretion of tumor necrosis factor-alpha and transforming growth factor-beta1 and expression of connexin 43 in human pleural mesothelial cells]. 2003 Zhonghua Jie He He Hu Xi Za Zhi pmid:12901826
Fan L and Xu J [Application progress of macrolide sustained therapy for bronchiectasis]. 2014 Zhonghua Jie He He Hu Xi Za Zhi pmid:24694975
Wang BF [A clinical study of 50 cases of Legionnaires disease]. 1992 Zhonghua Jie He He Hu Xi Za Zhi pmid:1306405
Yu L and Ran PX [Effects of erythromycin on the synthesis of interleukin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells]. 2009 Zhonghua Jie He He Hu Xi Za Zhi pmid:19567187
Zhong XN et al. [An experimental study on airway inflammation and remodeling in a rat model of chronic bronchitis and emphysema]. 2003 Zhonghua Jie He He Hu Xi Za Zhi pmid:14720429
Xiao W et al. [The imbalance of Th1/Th2 cytokine expression in peripheral blood mononuclear cell from asthmatic patients and the effect of erythromycin on these cytokines]. 2000 Zhonghua Jie He He Hu Xi Za Zhi pmid:11778516
Gao W et al. [Analysis of 9 cases of pulmonary tuberculosis complicated with legionnaires disease]. 1997 Zhonghua Jie He He Hu Xi Za Zhi pmid:10374448
Xu Z et al. [Effects of erythromycin and fosfomycin on Pseudomonas aeruginosa biofilm in vitro]. 2001 Zhonghua Jie He He Hu Xi Za Zhi pmid:11802985
Gu XH et al. [Effects of erythromycin on the twitching motility of Pseudomonas aeruginosa]. 2007 Zhonghua Jie He He Hu Xi Za Zhi pmid:17573001
Tan W et al. [The mechanism and effect of erythromycin in development of pulmonary fibrosis]. 1999 Zhonghua Jie He He Hu Xi Za Zhi pmid:11812357
Zhong XN and Guo SM [An experimental study on pulmonary vascular inflammation in a rat model of chronic bronchitis and emphysema]. 2006 Zhonghua Jie He He Hu Xi Za Zhi pmid:17045040
Liu J et al. [mRNA expression of basic fibroblast growth factor in the pulmonary tissues from rats repeatedly infected with mycoplasma pneumoniae]. 1999 Zhonghua Jie He He Hu Xi Za Zhi pmid:11775917
Li Y et al. [The effect of erythromycin on NF-kappa B activation and cytokines mRNA expression in bleomycin-induced pulmonary fibrosis in rats]. 1999 Zhonghua Jie He He Hu Xi Za Zhi pmid:11776779
Tang YC [Diagnosis and treatment of Legionnaires' disease from opportunistic infection]. 1987 Zhonghua Jie He He Hu Xi Za Zhi pmid:3440298
Lu W et al. [Analysis of 37 cases of pneumonia of Legionnaires' disease]. 1997 Zhonghua Jie He He Hu Xi Za Zhi pmid:10072832