erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Gaudreau C et al. | Long-Lasting Outbreak of Erythromycin- and Ciprofloxacin-Resistant Campylobacter jejuni Subspecies jejuni From 2003 to 2013 in Men Who Have Sex With Men, Quebec, Canada. | 2015 | Clin. Infect. Dis. | pmid:26187024 |
Dayie NT et al. | Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children. | 2015 | Microb. Drug Resist. | pmid:26172078 |
Guo MT et al. | Insights into the amplification of bacterial resistance to erythromycin in activated sludge. | 2015 | Chemosphere | pmid:25957255 |
Kasai A et al. | Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. | 2015 | J. Med. Microbiol. | pmid:25934551 |
Melkumyan AR et al. | Effects of antibiotic treatment on the lactobacillus composition of vaginal microbiota. | 2015 | Bull. Exp. Biol. Med. | pmid:25894774 |
Romaniszyn D et al. | Epidemiology, antibiotic consumption and molecular characterisation of Staphylococcus aureus infections--data from the Polish Neonatology Surveillance Network, 2009-2012. | 2015 | BMC Infect. Dis. | pmid:25888217 |
Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
Sessa R et al. | Effects of Mentha suaveolens essential oil on Chlamydia trachomatis. | 2015 | Biomed Res Int | pmid:25685793 |
Shi JG et al. | Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib. | 2015 | Clin. Pharmacol. Ther. | pmid:25670523 |
Xu CW et al. | First report of macrolide resistance gene erm(T) harbored by a novel small plasmid from Erysipelothrix rhusiopathiae. | 2015 | Antimicrob. Agents Chemother. | pmid:25666150 |
Naquin A et al. | Presence of antibiotic resistance genes in a sewage treatment plant in Thibodaux, Louisiana, USA. | 2015 | Bioresour. Technol. | pmid:25662190 |
Chan BC et al. | Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. | 2015 | J. Pharm. Pharmacol. | pmid:25212982 |
Haxel BR et al. | Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis. | 2015 | Laryngoscope | pmid:25425539 |
Berg C et al. | Significance of archaeal nitrification in hypoxic waters of the Baltic Sea. | 2015 | ISME J | pmid:25423026 |
Mazur CS et al. | P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. | 2015 | Toxicol. Lett. | pmid:25268938 |
Cochrane SA et al. | Synthesis of Tridecaptin-Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria. | 2015 | J. Med. Chem. | pmid:26636619 |
Liang Z et al. | Structural Correspondence of the Oriented Attachment Growth Mechanism of Crystals of the Pharmaceutical Dirithromycin. | 2015 | Langmuir | pmid:26632998 |
Shishkina AV et al. | Modeling Interactions of Erythromycin Derivatives with Ribosomes. | 2015 | Biochemistry Mosc. | pmid:26615442 |
Wilson DW et al. | Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. | 2015 | BMC Biol. | pmid:26187647 |
Kojima C et al. | Distribution of Antimicrobial Resistance in Campylobacter Strains Isolated from Poultry at a Slaughterhouse and Supermarkets in Japan. | 2015 | Biocontrol Sci | pmid:26412697 |
Yang Y et al. | Variation in Bordetella pertussis Susceptibility to Erythromycin and Virulence-Related Genotype Changes in China (1970-2014). | 2015 | PLoS ONE | pmid:26406905 |
O'Connor SE | Engineering of Secondary Metabolism. | 2015 | Annu. Rev. Genet. | pmid:26393965 |
Aydın S et al. | The joint acute effect of tetracycline, erythromycin and sulfamethoxazole on acetoclastic methanogens. | 2015 | Water Sci. Technol. | pmid:25909721 |
Mazumdar G and Shome K | Stevens-Johnson syndrome following use of metronidazole in a dental patient. | 2014 Jan-Feb | Indian J Pharmacol | pmid:24550598 |
Gustafsson F et al. | A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | 2014 | Toxicol. Sci. | pmid:24085192 |
Nikolay R et al. | Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli. | 2014 | Nucleic Acids Res. | pmid:24792169 |
Sanamrad A et al. | Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25056965 |
Pierson RC et al. | A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. | 2014 | Obstet Gynecol | pmid:25162251 |
Rozov-Ung I et al. | Detection of drug effects on gastric emptying and contractility using a wireless motility capsule. | 2014 | BMC Gastroenterol | pmid:24383478 |
Miyazaki M et al. | [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. | 2014 | Yakugaku Zasshi | pmid:24492229 |
Wang J et al. | [Drug susceptibility and homologous analysis on Corynebacterium striatum strains isolated from inpatients]. | 2014 | Zhonghua Yi Xue Za Zhi | pmid:25410920 |
Wu H et al. | Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea. | 2014 | Microb. Cell Fact. | pmid:25391994 |
Caierão J et al. | Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. | 2014 | PLoS ONE | pmid:25356595 |
Kara M et al. | Expression changes of antioxidant, apoptotic, anti-apoptotic genes and miR-15b-34a-21-98 in over tissue by using erythromycin, quinacrine and tetracycline in non-surgical sterilization. | 2014 | Mol. Biol. Rep. | pmid:25195052 |
Shera IA et al. | Unusual case of Hashimoto's encephalopathy and pseudo-obstruction in a patient with undiagnosed hypothyroidism: a case report. | 2014 | J Med Case Rep | pmid:25194644 |
Usui M et al. | Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. | 2014 | Vet. Rec. | pmid:25163817 |
Wyatt TA et al. | cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. | 2014 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25150062 |
Crumb WJ | Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. | 2014 | Br. J. Pharmacol. | pmid:24417241 |
Luan R et al. | [Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis]. | 2014 | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | pmid:24912643 |
Liu J et al. | Tissue distribution, bioconcentration, metabolism, and effects of erythromycin in crucian carp (Carassius auratus). | 2014 | Sci. Total Environ. | pmid:24911771 |
Piccinelli G et al. | In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. | 2014 | Antimicrob. Agents Chemother. | pmid:24379197 |
Ramos FL and Criner GJ | Use of long-term macrolide therapy in chronic obstructive pulmonary disease. | 2014 | Curr Opin Pulm Med | pmid:24378875 |
Johansson M et al. | Sequence-dependent elongation dynamics on macrolide-bound ribosomes. | 2014 | Cell Rep | pmid:24836000 |
Dechert-Schmitt AM et al. | Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. | 2014 | Nat Prod Rep | pmid:24514754 |
Melnik BC | The P450 system and mTORC1 signalling in acne. | 2014 | Exp. Dermatol. | pmid:24588627 |
Xiao C et al. | Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. | 2014 | J Perinat Med | pmid:24566358 |
Montes M et al. | What causes decreased erythromycin resistance in Streptococcus pyogenes? Dynamics of four clones in a southern European region from 2005 to 2012. | 2014 | J. Antimicrob. Chemother. | pmid:24562616 |
Benito D et al. | Genetic lineages, antimicrobial resistance, and virulence in Staphylococcus aureus of meat samples in Spain: analysis of immune evasion cluster (IEC) genes. | 2014 | Foodborne Pathog. Dis. | pmid:24479575 |
Boomkamp SD et al. | Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. | 2014 | Br. J. Pharmacol. | pmid:24467222 |
Aydin S et al. | Performance of anaerobic sequencing batch reactor in the treatment of pharmaceutical wastewater containing erythromycin and sulfamethoxazole mixture. | 2014 | Water Sci. Technol. | pmid:25429450 |