erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Schuster-Bruce M | Gastric emptying in the critically ill. | 2001 | Crit. Care Med. | pmid:11395631 |
Svejda J and Richter J | [The hepatotoxic action of erythromycin (author's transl)]. | 1975 | Cas. Lek. Cesk. | pmid:1139592 |
Rospide MF et al. | Comparative antimicrobial activity of ABT-773, a novel ketolide, tested against drug-resistant Gram-positive cocci and Haemophilus influenzae. | 2001 | Int. J. Antimicrob. Agents | pmid:11397614 |
Lim J and Yun H | Postantibiotic effects and postantibiotic sub-MIC effects of erythromycin, roxithromycin, tilmicosin, and tylosin on Pasteurella multocida. | 2001 | Int. J. Antimicrob. Agents | pmid:11397617 |
Usary J and Champney WS | Erythromycin inhibition of 50S ribosomal subunit formation in Escherichia coli cells. | 2001 | Mol. Microbiol. | pmid:11401702 |
Butrous G and Siegel RL | Sildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. | 2001 | Circulation | pmid:11401951 |
PÃriz S et al. | Comparison of erythromycin and oxytetracycline for the treatment of ovine footrot. | 2001 | Acta Vet. Hung. | pmid:11402641 |
Takahashi T et al. | Erythromycin attenuates an experimental model of chronic bronchiolitis via augmenting monocyte chemoattractant protein-1. | 2001 | Eur. Respir. J. | pmid:11405512 |
Ng E and Shah V | Erythromycin for feeding intolerance in preterm infants. | 2001 | Cochrane Database Syst Rev | pmid:11406010 |
Kawamura-Sato K et al. | Postantibiotic suppression effect of macrolides on the expression of flagellin in Pseudomonas aeruginosa and Proteus mirabilis. | 2001 | J. Infect. Chemother. | pmid:11406758 |
Hoban DJ et al. | Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: prevalence of mef(A) and erm(B) and susceptibilities to ketolides. | 2001 | Antimicrob. Agents Chemother. | pmid:11408241 |
Nilius AM et al. | Comparative in vitro activity of ABT-773, a novel antibacterial ketolide. | 2001 | Antimicrob. Agents Chemother. | pmid:11408246 |
Miller SD | Madura foot: treatment of Nocardia nova infection with antibiotics alone. | 2001 | Am J. Orthop. | pmid:11411876 |
Yin Y et al. | Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11412964 |
Chrysos E et al. | Erythromycin enhances oesophageal motility in patients with gastro-oesophageal reflux. | 2001 | ANZ J Surg | pmid:11413601 |
Losa M et al. | CI (critical incidents) vs. CI (corporate identity). | 2001 | Swiss Med Wkly | pmid:11416892 |
Grub S et al. | The interaction of saquinavir (soft gelatin capsule) with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients. | 2001 | Eur. J. Clin. Pharmacol. | pmid:11417442 |
Gregory ST et al. | Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21. | 2001 | J. Bacteriol. | pmid:11418580 |
Canzano JC and Lim JI | Pars plana vitrectomy for epiretinal membrane secondary to cat scratch neuroretinitis. | 2001 | Retina (Philadelphia, Pa.) | pmid:11421023 |
Courbot A et al. | [Sinobronchial syndrome]. | 2001 | Rev Mal Respir | pmid:11424716 |
Gutschow CA et al. | Bile exposure of the denervated stomach as an esophageal substitute. | 2001 | Ann. Thorac. Surg. | pmid:11426748 |
McGee L et al. | Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. | 2001 | J. Clin. Microbiol. | pmid:11427569 |
Tomich PK et al. | A transposon (Tn917) in Streptococcus faecalis that exhibits enhanced transposition during induction of drug resistance. | 1979 | Cold Spring Harb. Symp. Quant. Biol. | pmid:114353 |
Honba K et al. | [Erythromycin uptake pathways in Shigella]. | 2001 | Jpn J Antibiot | pmid:11436833 |
Komiya N and Tamaoki K | [Therapeutic effects of macrolides on patients with psoriasis vulgaris, pigmentary prurigo, or eosinophilic pustule folliculitis]. | 2001 | Jpn J Antibiot | pmid:11439883 |
Matsunaga Y et al. | [Therapeutic effects of macrolides on patients with palmoplantar pustulosis]. | 2001 | Jpn J Antibiot | pmid:11439885 |
Azuma A et al. | [Case of the bare lymphocyte syndrome successfully treated with long-term small dosage administration of erythromycin]. | 2001 | Jpn J Antibiot | pmid:11439887 |
Takahashi T et al. | [Effects of erythromycin on the Pseudomonas-induced rabbit diffuse panbronchiolitis model--the improvements in granuloma-like lesions with increasing production of MCP-1]. | 2001 | Jpn J Antibiot | pmid:11439890 |
Enomoto F et al. | [Effects of macrolides on cultured rat vascular cells]. | 2001 | Jpn J Antibiot | pmid:11439891 |
Hashimoto N et al. | [Effects of erythromycin on matrix metalloproteinase-9(MMP-9)and cell migration]. | 2001 | Jpn J Antibiot | pmid:11439893 |
Inesawa H et al. | [Effects of macrolide antibiotics on immune cells derived from human peripheral blood]. | 2001 | Jpn J Antibiot | pmid:11439894 |
Dobashi Y et al. | [Effects of macrolides on neutrophil apoptosis, IL-8 production, and neutrophil clearance mechanism]. | 2001 | Jpn J Antibiot | pmid:11439897 |
Taguchi Y | [Guidelines for small dosage macrolide therapy of patients with diffuse panbronchiolitis and reports of adverse effects]. | 2001 | Jpn J Antibiot | pmid:11439900 |
Tamaoki A et al. | [Effects and action mechanisms of macrolides on IgG- immune complex lung injury models]. | 2001 | Jpn J Antibiot | pmid:11439907 |
Idesaki M et al. | [Effects of various erythromycin derivatives on activation of transcription factors in airway epithelial cells]. | 2001 | Jpn J Antibiot | pmid:11439910 |
Brandt CM et al. | Macrolide resistance in Streptococcus pyogenes isolates from throat infections in the region of Aachen, Germany. | 2001 | Microb. Drug Resist. | pmid:11442342 |
Corneau N et al. | A coelectroporation method for the isolation of cryptic plasmids from Lactococcus lactis. | 2001 | Lett. Appl. Microbiol. | pmid:11442806 |
Garzotti M et al. | Coupling of a supercritical fluid chromatography system to a hybrid (Q-TOF 2) mass spectrometer: on-line accurate mass measurements. | 2001 | Rapid Commun. Mass Spectrom. | pmid:11445901 |
Dubois J and St -Pierre C | In vitro activity of ABT-773 versus macrolides and quinolones against resistant respiratory tract pathogens. | 2001 May-Jun | Diagn. Microbiol. Infect. Dis. | pmid:11448561 |
Lo Bue AM et al. | Antibacterial activity and post-antibiotic effect of flurithromycin compared with other macrolides and penicillins against periodontal pathogens. | 2001 | J Chemother | pmid:11450882 |
Gregory D et al. | Activity of penicillin, erythromycin, and cephalosporins against isolates of Corynebacterium diphtheriae from cutaneous lesions. | 1979 | J. Antimicrob. Chemother. | pmid:114513 |
Clarebout G et al. | Macrolide resistance gene mreA of Streptococcus agalactiae encodes a flavokinase. | 2001 | Antimicrob. Agents Chemother. | pmid:11451686 |
Goldstein EJ et al. | In vitro activities of ABT-773, a new ketolide, against aerobic and anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis. | 2001 | Antimicrob. Agents Chemother. | pmid:11451698 |
Jacobs JA et al. | Prevalence of macrolide resistance genes in clinical isolates of the Streptococcus anginosus ("S. milleri") group. | 2001 | Antimicrob. Agents Chemother. | pmid:11451701 |
De Mouy D et al. | Antibiotic susceptibility and mechanisms of erythromycin resistance in clinical isolates of Streptococcus agalactiae: French multicenter study. | 2001 | Antimicrob. Agents Chemother. | pmid:11451709 |
Yamada G et al. | Centrilobular nodules correlate with air trapping in diffuse panbronchiolitis during erythromycin therapy. | 2001 | Chest | pmid:11451838 |
Facinelli B et al. | Association between erythromycin resistance and ability to enter human respiratory cells in group A streptococci. | 2001 | Lancet | pmid:11454374 |
Piessevaux H et al. | Perception of changes in wall tension of the proximal stomach in humans. | 2001 | Gut | pmid:11454795 |
Ose L | [Encephalitis associated with mycoplasma pneumoniae infection in children]. | 1975 | Tidsskr. Nor. Laegeforen. | pmid:1145545 |
Cha S et al. | The emergence of erythromycin-resistant Streptococcus pyogenes in Seoul, Korea. | 2001 | J. Infect. Chemother. | pmid:11455497 |