erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Seroma D049291 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Microphthalmos D008850 1 associated lipids
Chalazion D017043 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Tooth Fractures D014082 2 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Fecal Incontinence D005242 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Abdominal Abscess D018784 2 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Kuwahara T et al. Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. 2013 J. Cardiovasc. Electrophysiol. pmid:23551640
Lozada LE et al. Development of pyloric stenosis after a 4-day course of oral erythromycin. 2013 Pediatr Emerg Care pmid:23558266
Cuello-García CA et al. Treating BCG-induced disease in children. 2013 Cochrane Database Syst Rev pmid:23440826
Jersild Jespersen M et al. [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. 2013 Ugeskr. Laeg. pmid:23462037
Jiang M and Pfeifer BA Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. 2013 Metab. Eng. pmid:23747605
Xia Q et al. Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. 2013 BMC Microbiol. pmid:23767761
Guan Y et al. [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. 2013 Zhongguo Zhong Yao Za Zhi pmid:23724685
Kamal A et al. Anti-tubercular agents. Part 8: synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazoles. 2013 Bioorg. Med. Chem. Lett. pmid:24206766
Rallis E et al. Topical 5% benzoyl peroxide and 3% erythromycin gel: experience with 191 patients with papulopustular acne. 2013 Acta Dermatovenerol Croat pmid:24183219
Sugino K et al. Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. 2013 Intern. Med. pmid:24292765
Goh S et al. Phage Ï•C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. 2013 MBio pmid:24255122
Horácio AN et al. The majority of adult pneumococcal invasive infections in Portugal are still potentially vaccine preventable in spite of significant declines of serotypes 1 and 5. 2013 PLoS ONE pmid:24066064
Guo L et al. Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. 2013 Toxicol. Sci. pmid:24052561
Guo MT et al. Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. 2013 Chemosphere pmid:24055024
Li YY et al. Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. 2013 BMC Genomics pmid:23902230
Link-Gelles R et al. Geographic and temporal trends in antimicrobial nonsusceptibility in Streptococcus pneumoniae in the post-vaccine era in the United States. 2013 J. Infect. Dis. pmid:23852588
Cai G et al. Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. 2013 J. Nat. Prod. pmid:24224794
Ong SJ et al. Staphylococcus aureus keratitis: a review of hospital cases. 2013 PLoS ONE pmid:24244625
Chroboczek T et al. Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. 2013 PLoS ONE pmid:24260092
Ansari NN et al. Treatment of chronic rhinosinusitis using erythromycin phonophoresis. 2013 Physiother Theory Pract pmid:22891948
Fang J et al. Dissecting the function of a protruding loop in AcrB trimerization. 2013 J. Biomol. Struct. Dyn. pmid:22877148
Chen DK et al. [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. 2013 Zhonghua Yi Xue Za Zhi pmid:24548451
Opdam FL et al. Breath tests to phenotype drug disposition in oncology. 2013 Clin Pharmacokinet pmid:23868281
Tsujimoto M et al. Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. 2013 Toxins (Basel) pmid:23965431
Petráčková D et al. Fitness and proteome changes accompanying the development of erythromycin resistance in a population of Escherichia coli grown in continuous culture. 2013 Microbiologyopen pmid:23996919
Sanz-Rodríguez N et al. [Accuracy of Etest method to study Campylobacter spp. susceptibility to erythromycin, ciprofloxacin and tetracycline]. 2013 Rev Esp Quimioter pmid:23817649
James GD et al. Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. 2013 Prim Care Respir J pmid:23839240
Parhi AK et al. Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. 2013 Bioorg. Med. Chem. Lett. pmid:23891185
Lee A Gastroparesis: what is the current state-of-the-art for evaluation and medical management? What are the results? 2013 J. Gastrointest. Surg. pmid:23801519
Liu ZX et al. [Inhibition of methanogenium by erythromycin and its domestation]. 2013 Huan Jing Ke Xue pmid:23798140
Pasquini L et al. Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. 2013 Sci. Total Environ. pmid:23827359
Malinka W et al. Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes. 2013 Bioorg. Med. Chem. pmid:23850103
Weber JM et al. Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations. 2013 Appl. Microbiol. Biotechnol. pmid:23604533
Yang X et al. Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China. 2013 Environ Sci Pollut Res Int pmid:23608973
Wittwer MB et al. Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. 2013 J. Med. Chem. pmid:23241029
Mavri A and Smole Možina S Resistance to bile salts and sodium deoxycholate in macrolide- and fluoroquinolone-susceptible and resistant Campylobacter jejuni and Campylobacter coli strains. 2013 Microb. Drug Resist. pmid:23289436
Lin KJ et al. Safety of macrolides during pregnancy. 2013 Am. J. Obstet. Gynecol. pmid:23254249
Sánchez Valenzuela A et al. Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods. 2013 Foodborne Pathog. Dis. pmid:23259502
Sanad YM et al. Molecular epidemiology and public health relevance of Campylobacter isolated from dairy cattle and European starlings in Ohio, USA. 2013 Foodborne Pathog. Dis. pmid:23259503
Haruna M et al. Prevalence and antimicrobial resistance of Campylobacter isolates from beef cattle and pigs in Japan. 2013 J. Vet. Med. Sci. pmid:23220905
Javid FA et al. Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. 2013 Eur. J. Pharmacol. pmid:23201066
Goodman CD et al. Chemobiosynthesis of new antimalarial macrolides. 2013 Antimicrob. Agents Chemother. pmid:23208707
Li X et al. Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. 2013 Eur J Med Chem pmid:23229056
Nunez-Samudio V and Chesneau O Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. 2013 Res. Microbiol. pmid:23261969
Hisatsune J et al. Emergence of Staphylococcus aureus carrying multiple drug resistance genes on a plasmid encoding exfoliative toxin B. 2013 Antimicrob. Agents Chemother. pmid:24080652
Paterna A et al. Short communication: In vitro antimicrobial susceptibility of Mycoplasma agalactiae strains isolated from dairy goats. 2013 J. Dairy Sci. pmid:24035026
Metzler K et al. Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae. 2013 J. Antimicrob. Chemother. pmid:23169894
Lasnier O et al. Two cases of corneal abrasions in children exposed to liquid detergent capsules. 2013 Can. J. Ophthalmol. pmid:23561618
Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern. 2013 Indian J. Med. Res. pmid:23563381
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400