erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kabir AR et al. | Management of bronchiolitis without antibiotics: a multicentre randomized control trial in Bangladesh. | 2009 | Acta Paediatr. | pmid:19572992 |
Oei J and Lui K | A placebo-controlled trial of low-dose erythromycin to promote feed tolerance in preterm infants. | 2001 | Acta Paediatr. | pmid:11529540 |
Gagliotti C et al. | A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. | 2015 | Acta Paediatr. | pmid:26058421 |
Jónsson B et al. | Ureaplasma urealyticum, erythromycin and respiratory morbidity in high-risk preterm neonates. | 1998 | Acta Paediatr. | pmid:9825977 |
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Wang JL et al. | Mycoplasma pneumoniae infection associated with hemolytic anemia--report of one case. | 2004 Sep-Oct | Acta Paediatr Taiwan | pmid:15868814 |
Kenyon S et al. | ORACLE--antibiotics for preterm prelabour rupture of the membranes: short-term and long-term outcomes. | 2002 | Acta Paediatr Suppl | pmid:12200889 |
Fenoll A et al. | Streptococcus pneumoniae in children in Spain: 1990-1999. | 2000 | Acta Paediatr Suppl | pmid:11194798 |
Sandström I | Ophthalmia neonatorum with special reference to Chlamydia trachomatis. Diagnosis and treatment. | 1986 | Acta Paediatr Scand Suppl | pmid:3107338 |
Huovila R | Whooping cough in Finland 1920-1978. Statistical and epidemiological studies. | 1982 | Acta Paediatr Scand Suppl | pmid:6305107 |
Trollfors B | Clinical course of whooping cough in children younger than six months. | 1979 | Acta Paediatr Scand | pmid:443033 |
Johansen K et al. | Absorption of erythromycin in children with gluten intolerance. | 1989 | Acta Paediatr Scand | pmid:2603725 |
Lagercrantz R et al. | Staphylococci and infection in maternity wards. IV. Studies on a partial rooming-in system. | 1973 | Acta Paediatr Scand | pmid:4491662 |
Sandström I et al. | Neonatal chlamydial conjunctivitis. A long term follow-up study. | 1988 | Acta Paediatr Scand | pmid:3258462 |
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Kubota M et al. | Erythromycin improves gastrointestinal motility in extremely low birthweight infants. | 1994 | Acta Paediatr Jpn | pmid:8203267 |
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Pardo Mateu L et al. | [Laryngeal infection by Rhodococcus equi in patient with AIDS]. | 2002 | Acta Otorrinolaringol Esp | pmid:12658846 |
Melon J and Reginster M | [Passage into normal salivary, lacrimal and nasal secretions of ampicillin and erythromycin administered intramuscularly]. | 1976 | Acta Otorhinolaryngol Belg | pmid:1028340 |
Hassid S | [Otitis media caused by Mycoplasma pneumoniae]. | 1985 | Acta Otorhinolaryngol Belg | pmid:3938913 |
Sundberg L et al. | The effect of erythromycin on the nasopharyngeal pathogens in children with secretory otitis media. | 1984 Mar-Apr | Acta Otolaryngol. | pmid:6609521 |
Björkwall T | Local treatment with antibiotics in cases of maxillary sinusitis. | 1966 | Acta Otolaryngol. | pmid:5992657 |
Axelsson A et al. | Treatment of acute maxillary sinusitis. IV. Ampicillin, cephradine and erythromycinestolate with and without irrigation. | 1975 May-Jun | Acta Otolaryngol. | pmid:1155056 |
Palva T et al. | Effect of erythromycin on adenoid bacteria. | 1986 Mar-Apr | Acta Otolaryngol. | pmid:3486544 |
Freijd A and Rynnel-Dagöö B | Isolation of nasopharyngeal beta-lactamase producing Haemophilus influenzae, in relation to antibiotic treatment of acute otitis media in infants. | 1983 Mar-Apr | Acta Otolaryngol. | pmid:6404124 |
Liu J et al. | Inhibitory effect of erythromycin on ion transport by stria vascularis and vestibular dark cells. | 1996 | Acta Otolaryngol. | pmid:8831844 |
Cervin A | The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis. | 2001 | Acta Otolaryngol. | pmid:11270500 |
LYSTAD A et al. | THE BACTERIAL FLORA OF SINUSITIS WITH AN IN VITRO STUDY OF THE BACTERIAL RESISTANCE TO ANTIBIOTICS. | 1964 | Acta Otolaryngol Suppl | pmid:14146702 |
Schalén L et al. | Acute laryngitis in adults: results of erythromycin treatment. | 1992 | Acta Otolaryngol Suppl | pmid:1632252 |
Hashiba M and Baba S | Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. | 1996 | Acta Otolaryngol Suppl | pmid:8908275 |
Erythromycin, past, present and future. Symposium, Vettere Konferense- og Studiesenter, Asker , Norway, September 16, 1983. | 1984 | Acta Otolaryngol Suppl | pmid:6594027 | |
Frøland SS | Legionella pneumonia--a neglected diagnosis? | 1984 | Acta Otolaryngol Suppl | pmid:6594028 |
Jerve F | Treatment of genital tract infections due to Chlamydia trachomatis. | 1984 | Acta Otolaryngol Suppl | pmid:6594029 |
Sundberg L et al. | Penetration of erythromycin through respiratory mucosa. A study using secretory otitis media as a model. | 1979 | Acta Otolaryngol Suppl | pmid:294806 |
Sundberg L | Antibiotic treatment of secretory otitis media. | 1984 | Acta Otolaryngol Suppl | pmid:6388231 |
Sandström I | Neonatal conjunctivitis caused by Chlamydia trachomatis. | 1984 | Acta Otolaryngol Suppl | pmid:6388234 |
Schreiner A | Pathogenicity of Branhamella catarrhalis. | 1984 | Acta Otolaryngol Suppl | pmid:6333774 |
Forsgren A and Walder M | Activity of common antibiotics against Branhamella catarrhalis, Haemophilus influenzae, pneumococci, group A streptococci and Staphylococcus aureus in 1983. | 1984 | Acta Otolaryngol Suppl | pmid:6437134 |
Trollfors B | Whooping cough--aspects of pathogenesis and treatment. | 1984 | Acta Otolaryngol Suppl | pmid:6093425 |
Sundberg L et al. | Tissue penetration of erythromycin in Waldeyer's ring and bacteriology of secretory otitis media. | 1981 | Acta Otolaryngol Suppl | pmid:6285661 |
Enomoto F et al. | Effect of erythromycin on otitis media with effusion in experimental rat model. | 1998 | Acta Otolaryngol Suppl | pmid:10095863 |
Sørensen TS et al. | The penetration of cefazolin, erythromycin and methicillin into human bone tissue. | 1978 | Acta Orthop Scand | pmid:735781 |
Kallesøe O and Jespersen A | Metastatic osteomyelitis following BCG vaccination. | 1978 | Acta Orthop Scand | pmid:354311 |
Mehta JS et al. | Subconjunctival crystals in paediatric blepharokeratoconjunctivitis. | 2006 | Acta Ophthalmol Scand | pmid:16879584 |
Stenberg K and MÃ¥rdh PA | Chlamydial conjunctivitis in neonates and adults. History, clinical findings and follow-up. | 1990 | Acta Ophthalmol (Copenh) | pmid:2080692 |
Norn MS | Localisation of bacteria on single eyelashes. | 1970 | Acta Ophthalmol (Copenh) | pmid:5468034 |
Mølgaard IL et al. | A study of inclusion conjunctivitis in newborn and young adults. Clinical picture, culture, conjunctival scrapings and cytology of the tear fluid in 12 cases. | 1983 | Acta Ophthalmol (Copenh) | pmid:6362323 |
Stenberg K and MÃ¥rdh PA | Treatment of concomitant eye and genital chlamydial infection with erythromycin and roxithromycin. | 1993 | Acta Ophthalmol (Copenh) | pmid:8362632 |