MeSH term | MeSH ID | Detail |
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Vagus Nerve Injuries | D061223 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Xing L et al. | ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer. | 2015 | PLoS ONE | pmid:26107936 |
Dridi B et al. | Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. | 2015 | Antimicrob. Agents Chemother. | pmid:26100702 |
Czarnetzki C et al. | Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial. | 2015 | JAMA Surg | pmid:26083537 |
Patti MG | Erythromycin Use Before Induction of General Endotracheal Anesthesia. | 2015 | JAMA Surg | pmid:26083012 |
Haenen CC et al. | [Rosacea fulminans in pregnancy]. | 2015 | Ned Tijdschr Geneeskd | pmid:26058762 |
Chew ML et al. | Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial. | 2015 | Clin Drug Investig | pmid:25808394 |
Ericson JE et al. | Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. | 2015 | J. Pediatr. Gastroenterol. Nutr. | pmid:25806675 |
Aydin S et al. | Application of real-time PCR to determination of combined effect of antibiotics on Bacteria, Methanogenic Archaea, Archaea in anaerobic sequencing batch reactors. | 2015 | Water Res. | pmid:25792437 |
Zhu Y et al. | Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". | 2015 | Sci Rep | pmid:25791905 |
Wang P et al. | Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. | 2015 | PLoS ONE | pmid:25781346 |
Zhou Y et al. | Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. | 2015 | Talanta | pmid:25770599 |
Tojima I et al. | Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. | 2015 | Auris Nasus Larynx | pmid:25769240 |
Johnson AC et al. | Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers. | 2015 | Sci. Total Environ. | pmid:25617699 |
Wang P et al. | Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas. | 2015 | Microb. Cell Fact. | pmid:25612661 |
Chiaverini C et al. | Oral erythromycin therapy in epidermolysis bullosa simplex generalized severe. | 2015 | Br. J. Dermatol. | pmid:25601422 |
Li Z et al. | New erythromycin derivatives enhance β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. | 2015 | Lett. Appl. Microbiol. | pmid:25588530 |
Gardiner SJ et al. | Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. | 2015 | Cochrane Database Syst Rev | pmid:25566754 |
Azadegan A et al. | Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. | 2015 | Ann Lab Med | pmid:25553281 |
Wu H et al. | Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25549616 |
Wang Z et al. | Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk. | 2015 | Food Chem | pmid:25308648 |
Hawkins PA et al. | Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States. | 2015 | Microb. Drug Resist. | pmid:25115711 |
Vallianou N et al. | Prevalence of macrolide, lincosamide, and streptogramin resistance among staphylococci in a tertiary care hospital in Athens, Greece. | 2015 | J Chemother | pmid:25112954 |
Kempe H et al. | Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. | 2015 | Pharm. Res. | pmid:25103333 |
Yang J et al. | Improving heterologous polyketide production in Escherichia coli by transporter engineering. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26062534 |
Muralidharan V and Striepen B | Teaching old drugs new tricks to stop malaria invasion in its tracks. | 2015 | BMC Biol. | pmid:26349580 |
Pavlova A and Gumbart JC | Parametrization of macrolide antibiotics using the force field toolkit. | 2015 | J Comput Chem | pmid:26280362 |
Feng T et al. | Insights into resistance mechanism of the macrolide biosensor protein MphR(A) binding to macrolide antibiotic erythromycin by molecular dynamics simulation. | 2015 | J. Comput. Aided Mol. Des. | pmid:26564143 |
Daghighi S et al. | Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. | 2015 | Int. J. Antimicrob. Agents | pmid:26526893 |
Bravo-Rodriguez K et al. | Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. | 2015 | Chem. Biol. | pmid:26526102 |
Han X et al. | Synthesis and structure-activity relationships of novel 9-oxime acylides with improved bactericidal activity. | 2015 | Bioorg. Med. Chem. | pmid:26349628 |
Wróblewska M and Winnicka K | The Effect of Cationic Polyamidoamine Dendrimers on Physicochemical Characteristics of Hydrogels with Erythromycin. | 2015 | Int J Mol Sci | pmid:26343637 |
Bolukaoto JY et al. | Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. | 2015 | BMC Res Notes | pmid:26289147 |
Liao CH et al. | DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26272095 |
Thomas L et al. | Ophthalmic Considerations in Stevens-Johnson Syndrome. | 2016 | J. Pediatr. | pmid:27318376 |
Tang C et al. | The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. | 2016 | Sci Rep | pmid:27897206 |
Tack J et al. | Motilin-induced gastric contractions signal hunger in man. | 2016 | Gut | pmid:25539673 |
de Jesus Gaffney V et al. | Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. | 2016 | Environ. Toxicol. Chem. | pmid:27061931 |
Caumes E et al. | [Donovanosis (granuloma inguinale)]. | 2016 | Ann Dermatol Venereol | pmid:27773509 |
Burr LD et al. | Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. | 2016 | Ann Am Thorac Soc | pmid:27464029 |
Ben Salem I et al. | Removal of Penicillin G and Erythromycin with Ionizing Radiation Followed by Biological Treatment. | 2016 | Curr. Microbiol. | pmid:27447798 |
Hsieh PF et al. | The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. | 2016 | Virulence | pmid:27029012 |
Baker KR et al. | A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. | 2016 | Antimicrob. Agents Chemother. | pmid:27458225 |
Juda M et al. | The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. | 2016 | Mem. Inst. Oswaldo Cruz | pmid:27008373 |
Pierattini EC et al. | Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. | 2016 | Sci. Total Environ. | pmid:27366984 |
Bhadra PK et al. | Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B. | 2016 | Org. Biomol. Chem. | pmid:27273525 |
Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
Entorf M et al. | Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. | 2016 | Vet. Microbiol. | pmid:26732695 |
Arenz S et al. | A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. | 2016 | Nat Commun | pmid:27380950 |
Takahashi T et al. | Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. | 2016 | Ann Lab Med | pmid:26522753 |
Snoeys J et al. | Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. | 2016 | Clin. Pharmacol. Ther. | pmid:26259716 |