MeSH term | MeSH ID | Detail |
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Vagus Nerve Injuries | D061223 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ung D et al. | Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis. | 2009 | Xenobiotica | pmid:19575604 |
Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
Emoto C et al. | Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human. | 2001 | Xenobiotica | pmid:11491388 |
Saitoh R et al. | Nonlinear intestinal pharmacokinetics of mitemcinal, the first acid-resistant non-peptide motilin receptor agonist, in rats. | 2007 | Xenobiotica | pmid:17926229 |
Ward KW et al. | Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human. | 2005 | Xenobiotica | pmid:16019946 |
Molnari JC and Myers AL | Carbonyl reduction of bupropion in human liver. | 2012 | Xenobiotica | pmid:22339467 |
Kaye B and Roberts DW | The metabolism of oxamniquine in the gut wall. | 1980 | Xenobiotica | pmid:7395269 |
Watanabe M et al. | Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo. | 1999 | Xenobiotica | pmid:10553724 |
Trepanier LA and Miller JL | NADH-dependent reduction of sulphamethoxazole hydroxylamine in dog and human liver microsomes. | 2000 | Xenobiotica | pmid:11307968 |
Kanazu T et al. | Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. I: evaluation of cynomolgus monkeys as surrogates for humans. | 2004 | Xenobiotica | pmid:15370956 |
Zhang Y et al. | [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. | 2014 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:24721407 |
Watanabe Y et al. | [Relationship between quality and serum level after the oral administration of commercial erythromycin tablets in man (author's transl)]. | 1977 | Yakugaku Zasshi | pmid:911413 |
Matsuoka M | [Study of macrolide, lincosamide, and streptogramin B antibiotics resistance in Staphylococcus aureus]. | 2000 | Yakugaku Zasshi | pmid:10774259 |
Nakamura H et al. | Effect of particle size on mixing degree in dispensation. | 2004 | Yakugaku Zasshi | pmid:15049131 |
Nakamura H et al. | Effect of mixing method on the mixing degree during the preparation of triturations. | 2004 | Yakugaku Zasshi | pmid:15049130 |
Watanabe Y et al. | [Effect of dissolving pH of enteric coating agent on bioavailability of enteric coated tablets of erythromycin in man (author's transl)]. | 1978 | Yakugaku Zasshi | pmid:30834 |
Miyazaki M et al. | [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. | 2014 | Yakugaku Zasshi | pmid:24492229 |
Otsuka M et al. | [Studies on fungicides. XIV. Effect of erythromycin on the growth of fungal mycelia (author's transl)]. | 1978 | Yakugaku Zasshi | pmid:566318 |
Xu P et al. | [Synthesis of derivatives of (9S) -9-hydroxyl-12-methylene erythromycin A and their antibacterial activity in vitro]. | 2007 | Yao Xue Xue Bao | pmid:17703771 |
Chen SX et al. | [Synthesis and antibacterial activity of 3-hydroxy-6-O-methylerythromycin-9-O-substituted oxime derivatives]. | 2001 | Yao Xue Xue Bao | pmid:12579933 |