MeSH term | MeSH ID | Detail |
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Abnormalities, Multiple | D000015 | 13 associated lipids |
Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kudoh S | [Pathophysiology of diffuse panbronchiolitis and progress of the therapy]. | 1996 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:9216178 |
Tenson T et al. | Erythromycin resistance peptides selected from random peptide libraries. | 1997 | J. Biol. Chem. | pmid:9211885 |
Itoh Z | Motilin and clinical application. | 1997 | Peptides | pmid:9210180 |
Kluger MT | Erythromycin--a pro-kinetic and pro-arrhythmogenic agent. | 1997 | Anaesth Intensive Care | pmid:9209631 |
Nakata K et al. | [Suppressive effect of clarithromycin on the production of verotoxin by E. coli O157]. | 1997 | Kansenshogaku Zasshi | pmid:9209125 |
Nakamura A | [Prevalence of antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in a children's hospital]. | 1997 | Kansenshogaku Zasshi | pmid:9209123 |
Vagliasindi M | Use of flurythromycin ethylsuccinate in infections of lower airways due to sensitive germs: multicenter comparative study with clarithromycin. | 1997 | Int J Clin Pharmacol Ther | pmid:9208340 |
Lagasse JP et al. | [Acute reversible pan-dysautonomia: effect of erythromycin on gastrointestinal involvement]. | 1997 | Gastroenterol. Clin. Biol. | pmid:9208000 |
Gleason PP et al. | Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia. | 1997 | JAMA | pmid:9207335 |
Rampe D and Murawsky MK | Blockade of the human cardiac K+ channel Kv1.5 by the antibiotic erythromycin. | 1997 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:9205959 |
Pacini N et al. | Antimicrobial susceptibility tests on anaerobic oral mixed cultures in periodontal diseases. | 1997 | J. Clin. Periodontol. | pmid:9205919 |
PalacÃn C et al. | In vitro anti-Helicobacter pylori activity of ebrotidine. | 1997 | Arzneimittelforschung | pmid:9205746 |
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Rosser EJ | German shepherd dog pyoderma: a prospective study of 12 dogs. | 1997 Jul-Aug | J Am Anim Hosp Assoc | pmid:9204474 |
Caron D et al. | Skin tolerance of adapalene 0.1% gel in combination with other topical antiacne treatments. | 1997 | J. Am. Acad. Dermatol. | pmid:9204088 |
Kabir I et al. | Erythromycin and trimethoprim-sulphamethoxazole in the treatment of cholera in children. | 1996 | J Diarrhoeal Dis Res | pmid:9203786 |
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Shimada T et al. | Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans. | 1997 | Arch. Toxicol. | pmid:9195021 |
Pacifico L et al. | Ureaplasma urealyticum and pulmonary outcome in a neonatal intensive care population. | 1997 | Pediatr. Infect. Dis. J. | pmid:9194108 |
Huovinen P et al. | The relationship between erythromycin consumption and resistance in Finland. Finnish Study Group for Antimicrobial Resistance. | 1997 | Ciba Found. Symp. | pmid:9189633 |
Hanada E et al. | Determination of erythromycin concentrations in rat plasma and liver by high-performance liquid chromatography with amperometric detection. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9188840 |
Reines HD et al. | Use of standard colon preparation in elective colectomy for carcinoma of the colon. | 1977 Nov-Dec | Rev Surg | pmid:918536 |
Roblin PM et al. | In-vitro activity of dirithromycin against Chlamydia pneumoniae. | 1997 | J. Antimicrob. Chemother. | pmid:9184366 |
Xia HX et al. | Clarithromycin resistance in Helicobacter pylori: prevalence in untreated dyspeptic patients and stability in vitro. | 1996 | J. Antimicrob. Chemother. | pmid:9182104 |
Roe DE et al. | Mobile rRNA methylase genes coding for erythromycin resistance in Actinobacillus actinomycetemcomitans. | 1996 | J. Antimicrob. Chemother. | pmid:9182102 |
Hofstetter A | [Mycoplasma infections of the genito-urinary tract (author's transl)]. | 1977 | Schweiz. Rundsch. Med. Prax. | pmid:918003 |
Resnick J et al. | Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. | 1997 | Am. J. Gastroenterol. | pmid:9177505 |
Young H et al. | Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin. | 1997 | Int J STD AIDS | pmid:9175650 |
Rybak MJ et al. | Pharmacodynamics of RP 59500 (quinupristin-dalfopristin) administered by intermittent versus continuous infusion against Staphylococcus aureus-infected fibrin-platelet clots in an in vitro infection model. | 1997 | Antimicrob. Agents Chemother. | pmid:9174199 |
Gibert Agulló A et al. | [Generalized acute exanthematous pustulosis: two case reports]. | 1997 | An. Esp. Pediatr. | pmid:9173852 |
Berg-Candolfi M et al. | Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression. | 1996 | Xenobiotica | pmid:9173679 |
Piérard GE | [Pharma Clinics. Drug of the month. Benzamycin, an up-date on topical treatment of acne]. | 1997 | Rev Med Liege | pmid:9173479 |
Koch B et al. | Construction of specific erythromycin resistance mutations in the temperate lactococcal bacteriophage TP901-1 and their use in studies of phage biology. | 1997 | Appl. Environ. Microbiol. | pmid:9172365 |
Leloup L et al. | Single-crossover integration in the Lactobacillus sake chromosome and insertional inactivation of the ptsI and lacL genes. | 1997 | Appl. Environ. Microbiol. | pmid:9172327 |
Somkuti GA et al. | Molecular properties of the erythromycin resistance plasmid pPV141 from Staphylococcus chromogenes. | 1997 | Plasmid | pmid:9169203 |
Scalabrino G et al. | Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord. | 1997 | Exp. Neurol. | pmid:9168827 |
Lin JC and Quasny HA | QT prolongation and development of torsades de pointes with the concomitant administration of oral erythromycin base and quinidine. | 1997 May-Jun | Pharmacotherapy | pmid:9165570 |
Cheng CL et al. | Steady-state pharmacokinetics of delavirdine in HIV-positive patients: effect on erythromycin breath test. | 1997 | Clin. Pharmacol. Ther. | pmid:9164415 |
Yanagihara K et al. | [Efficacy of erythromycin inhalation in chronic respiratory infection caused by Pseudomonas aeruginosa]. | 1997 | Kansenshogaku Zasshi | pmid:9164089 |
Sugihara E | Effect of macrolide antibiotics on neutrophil function in human peripheral blood. | 1997 | Kansenshogaku Zasshi | pmid:9164088 |
Hessler PE et al. | Isolation of isoflavones from soy-based fermentations of the erythromycin-producing bacterium Saccharopolyspora erythraea. | 1997 | Appl. Microbiol. Biotechnol. | pmid:9163954 |
Heaton MP and Handwerger S | Conjugative mobilization of a vancomycin resistance plasmid by a putative Enterococcus faecium sex pheromone response plasmid. | 1995 | Microb. Drug Resist. | pmid:9158753 |
Matsuhashi M et al. | Cellular signals regulating antibiotic sensitivities of bacteria. | 1996 | Microb. Drug Resist. | pmid:9158728 |
Mitsuyama T et al. | Inhibition by erythromycin of human pulmonary artery endothelial cell injury induced by human neutrophils. | 1997 | Respiration | pmid:9154672 |
Carroll KC et al. | Susceptibility of beta-hemolytic streptococci to nine antimicrobial agents among four medical centers in Salt Lake City, Utah, USA. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9154408 |