MeSH term | MeSH ID | Detail |
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Abnormalities, Multiple | D000015 | 13 associated lipids |
Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Adderson E et al. | A community pseudo-outbreak of invasive Staphylococcus aureus infection. | 2000 | Diagn. Microbiol. Infect. Dis. | pmid:10904197 |
van Erpecum KJ et al. | Review article: agents affecting gall-bladder motility--role in treatment and prevention of gallstones. | 2000 | Aliment. Pharmacol. Ther. | pmid:10903008 |
Wehbeh H et al. | Erythromycin for chlamydiasis in pregnant women. Assessing adherence to a standard multiday, multidose course. | 2000 | J Reprod Med | pmid:10900579 |
Tait-Kamradt A et al. | Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage. | 2000 | Antimicrob. Agents Chemother. | pmid:10898684 |
Schmitz FJ et al. | Distribution of macrolide-resistance genes in Staphylococcus aureus blood-culture isolates from fifteen German university hospitals. M.A.R.S. Study Group. Multicentre Study on Antibiotic Resistance in Staphylococci. | 2000 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10898143 |
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Barrett-Connor E | Current status of the treatment of syphilis. | 1975 | West. J. Med. | pmid:1089007 |
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Chiba T et al. | Motilides accelerate regional gastrointestinal transit in the dog. | 2000 | Aliment. Pharmacol. Ther. | pmid:10886053 |
Baltch AL et al. | Antibacterial effect of telithromycin (HMR 3647) and comparative antibiotics against intracellular Legionella pneumophila. | 2000 | J. Antimicrob. Chemother. | pmid:10882688 |
Yan JJ et al. | Prevalence of polyclonal mefA-containing isolates among erythromycin-resistant group A streptococci in Southern Taiwan. | 2000 | J. Clin. Microbiol. | pmid:10878028 |
Lazarczyk DA and Duffy MC | Erythromycin-induced primary biliary cirrhosis. | 2000 | Dig. Dis. Sci. | pmid:10877225 |
Kanamitsu S et al. | Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4. | 2000 | Pharm. Res. | pmid:10870985 |
Cowles VE et al. | Effect of novel motilide ABT-229 versus erythromycin and cisapride on gastric emptying in dogs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10869416 |
Pandey RC and Rinehart KL | Polyene antibiotics. VII. Carbon-13 nuclear magnetic resonance evidence for cyclic hemiketals in the polyene antibiotics amphotericin B, nystatin A1, tetrin A, tetrin B, lucensomycin, and pimaricin1,2. | 1976 | J. Antibiot. | pmid:1086913 |
Fujita K et al. | Effects of macrolides on interleukin-8 secretion from human nasal epithelial cells. | 2000 | Eur Arch Otorhinolaryngol | pmid:10867834 |
Quintieri L et al. | In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A. | 2000 | Cancer Res. | pmid:10866316 |
Stenmark HG et al. | Biomimetic synthesis of macrolide/ketolide metabolites through a selective N-demethylation reaction. | 2000 | J. Org. Chem. | pmid:10864780 |
Wilkinson D et al. | Trial-of-antibiotic algorithm for the diagnosis of tuberculosis in a district hospital in a developing country with high HIV prevalence. | 2000 | Int. J. Tuberc. Lung Dis. | pmid:10864181 |
Jones RN et al. | In vitro activity of selected cephalosporins and erythromycin against staphylococci and pneumococci isolated at 38 North American medical centers participating in the SENTRY Antimicrobial Surveillance Program, 1997-1998. | 2000 | Diagn. Microbiol. Infect. Dis. | pmid:10863103 |
Davies JL et al. | Studies on the interaction of fermentation and microfiltration operations: erythromycin recovery from Saccharopolyspora erythraea fermentation broths. | 2000 | Biotechnol. Bioeng. | pmid:10862681 |
Stephenson GA | Structure determination from conventional powder diffraction data: application to hydrates, hydrochloride salts, and metastable polymorphs. | 2000 | J Pharm Sci | pmid:10861598 |
Cull SG et al. | Room-temperature ionic liquids as replacements for organic solvents in multiphase bioprocess operations. | 2000 | Biotechnol. Bioeng. | pmid:10861402 |
Davies TA et al. | Antipneumococcal activity of ABT-773 compared to those of 10 other agents. | 2000 | Antimicrob. Agents Chemother. | pmid:10858350 |
Betriu C et al. | Comparative in vitro activities of linezolid, quinupristin-dalfopristin, moxifloxacin, and trovafloxacin against erythromycin-susceptible and -resistant streptococci. | 2000 | Antimicrob. Agents Chemother. | pmid:10858339 |
Plouffe J et al. | Clinical efficacy of intravenous followed by oral azithromycin monotherapy in hospitalized patients with community-acquired pneumonia. The Azithromycin Intravenous Clinical Trials Group. | 2000 | Antimicrob. Agents Chemother. | pmid:10858333 |
Alonso A et al. | Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance. | 2000 | Antimicrob. Agents Chemother. | pmid:10858330 |
Ohmori M et al. | Effect of erythromycin on ischemia-reperfusion injury of liver in rats. | 2000 | Transplant. Proc. | pmid:10856595 |
Meisels HI and Peyman GA | Intravitreal erythromycin in the treatment of induced staphylococcal endophthalmitis. | 1976 | Ann Ophthalmol | pmid:1085597 |
Thami GP and Kanwar AJ | Red facial pseudochromhidrosis. | 2000 | Br. J. Dermatol. | pmid:10848751 |
Heikkinen T et al. | The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin. | 2000 | BJOG | pmid:10847234 |
Matsui S et al. | [Rheumatoid arthritis-associated bronchiolitis successfully treated with erythromycin]. | 2000 | Nihon Kokyuki Gakkai Zasshi | pmid:10846401 |
Takahashi Y et al. | Accurate mass determination by multiple sprayers nano-electrospray mass spectrometry on a magnetic sector instrument. | 2000 | Rapid Commun. Mass Spectrom. | pmid:10844730 |
Jackson LA et al. | Past use of erythromycin, tetracycline, or doxycycline is not associated with risk of first myocardial infarction. | 2000 | J. Infect. Dis. | pmid:10839759 |
Schmitz FJ et al. | Prevalence of macrolide-resistance genes in Staphylococcus aureus and Enterococcus faecium isolates from 24 European university hospitals. | 2000 | J. Antimicrob. Chemother. | pmid:10837446 |
Xia M et al. | Gonorrhea among men who have sex with men: outbreak caused by a single genotype of erythromycin-resistant Neisseria gonorrhoeae with a single-base pair deletion in the mtrR promoter region. | 2000 | J. Infect. Dis. | pmid:10837198 |
Cosgrove DM et al. | The management of Hemophilus influenzae, Type B, pericarditis. | 1976 | Ann. Thorac. Surg. | pmid:1083717 |
Jasir A et al. | High rate of tetracycline resistance in Streptococcus pyogenes in Iran: an epidemiological study. | 2000 | J. Clin. Microbiol. | pmid:10834960 |
Wood KE et al. | Phlegmasia cerulea dolens with compartment syndrome: a complication of femoral vein catheterization. | 2000 | Crit. Care Med. | pmid:10834724 |
Privitera G et al. | Transfer of multiple antibiotic resistance between subspecies of Bacteroides fragilis. | 1979 | J. Infect. Dis. | pmid:108340 |
Miyashita N et al. | In vitro susceptibility of 7.5-kb common plasmid-free Chlamydia trachomatis strains. | 2000 | Microbiol. Immunol. | pmid:10832970 |
Aarestrup FM et al. | Antimicrobial susceptibility and presence of resistance genes in staphylococci from poultry. | 2000 | Vet. Microbiol. | pmid:10831857 |
Usiskin SI et al. | Retreatment with clozapine after erythromycin-induced neutropenia. | 2000 | Am J Psychiatry | pmid:10831491 |
Ishioka S et al. | An autopsy case of diffuse panbronchiolitis associated with lung cancer. | 2000 | Intern. Med. | pmid:10830183 |
Holm M and Tärnvik A | Hospitalization due to Pasteurella multocida-infected animal bite wounds: correlation with inadequate primary antibiotic medication. | 2000 | Scand. J. Infect. Dis. | pmid:10826905 |
Zhou J et al. | Separation and determination of the macrolide antibiotics (erythromycin, spiramycin and oleandomycin) by capillary electrophoresis coupled with fast reductive voltammetric detection. | 2000 | Electrophoresis | pmid:10826680 |
Goldman RC and Tipper DJ | Morphology and patterns of protein synthesis during sporulation of Bacillus subtilis Eryr spo(Ts) mutants. | 1979 | J. Bacteriol. | pmid:108263 |
Govaerts C et al. | Investigation of unknown related substances in commercial erythromycin samples with liquid chromatography/mass spectrometry. | 2000 | Rapid Commun. Mass Spectrom. | pmid:10825252 |
Watkins PB | Erythromycin breath test. | 2000 | Clin. Pharmacol. Ther. | pmid:10824637 |
Gururaj VJ et al. | Triacetyloleandomycin in streptococcal throat infections. A reappraisal of an older antibiotic. | 1976 | Clin Pediatr (Phila) | pmid:1082408 |