erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

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Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Thomas L et al. Ophthalmic Considerations in Stevens-Johnson Syndrome. 2016 J. Pediatr. pmid:27318376
Tang C et al. The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. 2016 Sci Rep pmid:27897206
Sun H et al. Mechanism Underlying Time-dependent Cross-phenomenon between Concentration-response Curves and Concentration Addition Curves: A Case Study of Sulfonamides-Erythromycin mixtures on Escherichia coli. 2016 Sci Rep pmid:27644411
Mombelli A et al. Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci. 2016 J. Periodontol. pmid:26654350
Ulanovsky I et al. Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. 2016 Isr. Med. Assoc. J. pmid:28471562
Tack J et al. Motilin-induced gastric contractions signal hunger in man. 2016 Gut pmid:25539673
de Jesus Gaffney V et al. Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. 2016 Environ. Toxicol. Chem. pmid:27061931
Caumes E et al. [Donovanosis (granuloma inguinale)]. 2016 Ann Dermatol Venereol pmid:27773509
Caumes E et al. [Lymphogranuloma venereum]. 2016 Ann Dermatol Venereol pmid:27773504
Burr LD et al. Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. 2016 Ann Am Thorac Soc pmid:27464029
Ben Salem I et al. Removal of Penicillin G and Erythromycin with Ionizing Radiation Followed by Biological Treatment. 2016 Curr. Microbiol. pmid:27447798
Wu L et al. Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. 2016 PLoS ONE pmid:27447724
Hsieh PF et al. The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. 2016 Virulence pmid:27029012
Baker KR et al. A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. 2016 Antimicrob. Agents Chemother. pmid:27458225
Juda M et al. The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. 2016 Mem. Inst. Oswaldo Cruz pmid:27008373
Cui B et al. Selection of suitable reference genes for gene expression studies in Staphylococcus capitis during growth under erythromycin stress. 2016 Mol. Genet. Genomics pmid:27000656
Zhang A et al. Molecular subtyping and erythromycin resistance of Campylobacter in China. 2016 J. Appl. Microbiol. pmid:26999516
Pierattini EC et al. Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. 2016 Sci. Total Environ. pmid:27366984
Bhadra PK et al. Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B. 2016 Org. Biomol. Chem. pmid:27273525
Topp E et al. Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. 2016 Sci. Total Environ. pmid:27096634
Li X et al. Macrolides use and the risk of sudden cardiac death. 2016 Expert Rev Anti Infect Ther pmid:27086751
Cheng Y et al. Comparative study between macrolide regulatory proteins MphR(A) and MphR(E) in ligand identification and DNA binding based on the rapid in vitro detection system. 2016 Anal Bioanal Chem pmid:26753969
Entorf M et al. Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. 2016 Vet. Microbiol. pmid:26732695
Gupta P et al. Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. 2016 Nat. Chem. Biol. pmid:26727240
Arenz S et al. A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. 2016 Nat Commun pmid:27380950
Takahashi T et al. Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. 2016 Ann Lab Med pmid:26522753
Snoeys J et al. Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. 2016 Clin. Pharmacol. Ther. pmid:26259716
Vlakh EG et al. Preparation and characterization of macroporous monoliths imprinted with erythromycin. 2015 J Sep Sci pmid:26033867
Wang L et al. Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. 2015 Lett. Appl. Microbiol. pmid:26031793
Wang Z et al. MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. 2015 PLoS ONE pmid:25706647
Yoon IA et al. Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. 2015 Int. J. Infect. Dis. pmid:26026823
Gherardi G et al. Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. 2015 Eur. J. Clin. Microbiol. Infect. Dis. pmid:26024763
Hersch M et al. Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. 2015 J Crit Care pmid:25746849
Lee S et al. Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB. 2015 J. Microbiol. pmid:25740377
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Abreu AC et al. Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. 2015 Microb. Drug Resist. pmid:25734256
Chemler JA et al. Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination. 2015 J. Am. Chem. Soc. pmid:26230368
Ansari NN et al. A randomized clinical trial comparing pulsed ultrasound and erythromycin phonophoresis in the treatment of patients with chronic rhinosinusitis. 2015 Physiother Theory Pract pmid:25495769
Nagelreiter C et al. Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. 2015 Int J Pharm pmid:25475015
Harmer CJ et al. A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. 2015 J. Antimicrob. Chemother. pmid:25468903
Siekmeier R et al. Inhalation of macrolides: a novel approach to treatment of pulmonary infections. 2015 Adv. Exp. Med. Biol. pmid:25252902
Chen Y et al. The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. 2015 Bioprocess Biosyst Eng pmid:25042891
Song LY et al. Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action. 2015 Antimicrob. Agents Chemother. pmid:26711761
Fedashchin A et al. Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis. 2015 FEMS Microbiol. Lett. pmid:26468041
Lu H et al. High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis. 2015 Emerg Microbes Infect pmid:26038763
Yi X et al. Improved detection of multiple environmental antibiotics through an optimized sample extraction strategy in liquid chromatography-mass spectrometry analysis. 2015 Anal Bioanal Chem pmid:26449847
Ayazi P et al. Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. 2015 Prague Med Rep pmid:26445390
Peyre L et al. High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. 2015 Toxicol In Vitro pmid:26239606
Banik A et al. Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital. 2015 J Infect Dev Ctries pmid:26230122
Wang Z et al. Direct Detection of Erythromycin-Resistant Bordetella pertussis in Clinical Specimens by PCR. 2015 J. Clin. Microbiol. pmid:26224847