erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Hu H et al. | A case of diffuse panbronchiolitis. | 1996 | Chin. Med. J. | pmid:9275329 |
| Anderson KL | Genetic manipulation of anaerobic cellulolytic bacteria. | 1997 | SAAS Bull. Biochem. Biotechnol. | pmid:9274059 |
| Schaller U et al. | [Ophthalmia neonatorum caused by Chlamydia trachomatis. Rapid diagnosis and therapy]. | 1997 | Ophthalmologe | pmid:9273028 |
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| Takahashi Y et al. | Effects of indomethacin, dexamethasone, and erythromycin on endotoxin-induced intraepithelial mucus production of rat nasal epithelium. | 1997 | Ann. Otol. Rhinol. Laryngol. | pmid:9270434 |
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| Oesterheld JR | Erythromycin and clomipramine: noncompetitive inhibition of demethylation. | 1996 | J Child Adolesc Psychopharmacol | pmid:9231314 |
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| Takizawa H et al. | Erythromycin modulates IL-8 expression in normal and inflamed human bronchial epithelial cells. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9230759 |
| Kobayashi T et al. | Ototoxic effect of erythromycin on cochlear potentials in the guinea pig. | 1997 | Ann. Otol. Rhinol. Laryngol. | pmid:9228863 |
| Handsfield HH | Azithromycin in gonorrhoea. | 1997 | Int J STD AIDS | pmid:9228599 |
| Sefton AM et al. | The in-vitro activity of trovafloxacin, a new fluoroquinolone, against Gram-positive bacteria. | 1997 | J. Antimicrob. Chemother. | pmid:9222071 |
| Onody C et al. | Lack of resistance to erythromycin, rifampicin and ciprofloxacin in 98 clinical isolates of Legionella pneumophila. | 1997 | J. Antimicrob. Chemother. | pmid:9222053 |
| Gaudreau C and Gilbert H | Comparison of disc diffusion and agar dilution methods for antibiotic susceptibility testing of Campylobacter jejuni subsp. jejuni and Campylobacter coli. | 1997 | J. Antimicrob. Chemother. | pmid:9222038 |
| Hanson MR and Bogorad L | Effects of erythromycin on membrane-bound chloroplast ribosomes from wild-type Chlamydomonas reinhardi and erythromycin-resistant mutants. | 1977 | Biochim. Biophys. Acta | pmid:921999 |
| Jacobsen JR et al. | Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase. | 1997 | Science | pmid:9219693 |
| Antsaklis A et al. | Erythromycin treatment for subclinical Ureaplasma urealyticum infection in preterm labor. | 1997 Mar-Apr | Fetal. Diagn. Ther. | pmid:9218948 |
| Hoppe JE and Tschirner T | Comparison of Etest and agar dilution for testing the activity of three macrolides against Bordetella parapertussis. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9218920 |
| Annese V et al. | Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218089 |
| Brand RM et al. | Transdermal delivery of erythromycin lactobionate--implications for the therapy of gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218087 |