erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (20)
- J. Antimicrob. Chemother. (9)
- Drug Metab. Dispos. (2)
- Others (20)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bowie WR et al. | Efficacy of treatment regimens for lower urogenital Chlamydia trachomatis infection in women. | 1982 | Am. J. Obstet. Gynecol. | pmid:7055176 |
| McGregor JA et al. | Cervicovaginal microflora and pregnancy outcome: results of a double-blind, placebo-controlled trial of erythromycin treatment. | 1990 | Am. J. Obstet. Gynecol. | pmid:2240110 |
| KIEFER L et al. | The placental transfer of erythomycin. | 1955 | Am. J. Obstet. Gynecol. | pmid:13218094 |
| Andrews JI et al. | Group B streptococci causing neonatal bloodstream infection: antimicrobial susceptibility and serotyping results from SENTRY centers in the Western Hemisphere. | 2000 | Am. J. Obstet. Gynecol. | pmid:11035326 |
| Charles AG et al. | Asymptomatic gonorrhea in prenatal patients. | 1970 | Am. J. Obstet. Gynecol. | pmid:5505990 |
| Beckner RR et al. | Ototoxicity of erythromycin gluceptate. | 1981 | Am. J. Obstet. Gynecol. | pmid:7211980 |
| McFarlin BL et al. | Epidemic syphilis: maternal factors associated with congenital infection. | 1994 | Am. J. Obstet. Gynecol. | pmid:8116709 |
| Gauthier DW et al. | Expectant management of premature rupture of membranes with amniotic fluid cultures positive for Ureaplasma urealyticum alone. | 1994 | Am. J. Obstet. Gynecol. | pmid:8116718 |
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| Klebanoff MA et al. | Outcome of the Vaginal Infections and Prematurity Study: results of a clinical trial of erythromycin among pregnant women colonized with group B streptococci. | 1995 | Am. J. Obstet. Gynecol. | pmid:7755068 |
| Alger LS and Lovchik JC | Comparative efficacy of clindamycin versus erythromycin in eradication of antenatal Chlamydia trachomatis. | 1991 | Am. J. Obstet. Gynecol. | pmid:1872343 |
| Eschenbach DA et al. | A randomized placebo-controlled trial of erythromycin for the treatment of Ureaplasma urealyticum to prevent premature delivery. The Vaginal Infections and Prematurity Study Group. | 1991 | Am. J. Obstet. Gynecol. | pmid:2003533 |
| Romero R et al. | Antibiotic treatment of preterm labor with intact membranes: a multicenter, randomized, double-blinded, placebo-controlled trial. | 1993 | Am. J. Obstet. Gynecol. | pmid:8238130 |
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| Jones RB | New treatments for Chlamydia trachomatis. | 1991 | Am. J. Obstet. Gynecol. | pmid:2039033 |
| Yost NP et al. | An appraisal of treatment guidelines for antepartum community-acquired pneumonia. | 2000 | Am. J. Obstet. Gynecol. | pmid:10920320 |
| Lin KJ et al. | Safety of macrolides during pregnancy. | 2013 | Am. J. Obstet. Gynecol. | pmid:23254249 |
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| Croak A et al. | Predominance of serotype V and frequency of erythromycin resistance in Streptococcus agalactiae in Ohio. | 2003 | Am. J. Obstet. Gynecol. | pmid:12748459 |
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| Mercer BM et al. | Erythromycin therapy in preterm premature rupture of the membranes: a prospective, randomized trial of 220 patients. | 1992 | Am. J. Obstet. Gynecol. | pmid:1550145 |
| McGregor JA et al. | Adjunctive erythromycin treatment for idiopathic preterm labor: results of a randomized, double-blinded, placebo-controlled trial. | 1986 | Am. J. Obstet. Gynecol. | pmid:3511709 |
| Tarnow-Mordi W et al. | Randomized controlled trials of antibiotics in preterm labor. | 1994 | Am. J. Obstet. Gynecol. | pmid:8092243 |
| Cimolai N | Ocular methicillin-resistant Staphylococcus aureus infections in a newborn intensive care cohort. | 2006 | Am. J. Ophthalmol. | pmid:16815280 |
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| MARR WG et al. | Further studies on the effect of agents on regeneration of corneal epithelium. | 1954 | Am. J. Ophthalmol. | pmid:13148284 |
| NAIB K et al. | Observations on the ocular effects of erythromycin. | 1955 | Am. J. Ophthalmol. | pmid:14350055 |
| Tarizzo ML and Nabli B | The effect of antibiotics on the growth of TRIC agents in embryonated eggs. | 1967 | Am. J. Ophthalmol. | pmid:6067315 |
| Ghione M et al. | Research on factors influencing experimental chemotherapy tests in trachoma. | 1967 | Am. J. Ophthalmol. | pmid:6067316 |
| Newman PE et al. | A cluster of cases of Mycobacterium chelonei keratitis associated with outpatient office procedures. | 1984 | Am. J. Ophthalmol. | pmid:6702973 |