erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cuello-GarcÃa CA et al. | Treating BCG-induced disease in children. | 2013 | Cochrane Database Syst Rev | pmid:23440826 |
Jersild Jespersen M et al. | [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. | 2013 | Ugeskr. Laeg. | pmid:23462037 |
Horácio AN et al. | The majority of adult pneumococcal invasive infections in Portugal are still potentially vaccine preventable in spite of significant declines of serotypes 1 and 5. | 2013 | PLoS ONE | pmid:24066064 |
Li YY et al. | Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. | 2013 | BMC Genomics | pmid:23902230 |
Cai G et al. | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. | 2013 | J. Nat. Prod. | pmid:24224794 |
Fang J et al. | Dissecting the function of a protruding loop in AcrB trimerization. | 2013 | J. Biomol. Struct. Dyn. | pmid:22877148 |
Opdam FL et al. | Breath tests to phenotype drug disposition in oncology. | 2013 | Clin Pharmacokinet | pmid:23868281 |
Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
Pasquini L et al. | Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. | 2013 | Sci. Total Environ. | pmid:23827359 |
Heelan K et al. | Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. | 2012 Sep-Oct | Pediatr Dermatol | pmid:21906149 |
Lian W et al. | Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. | 2012 Oct-Dec | Biosens Bioelectron | pmid:22683249 |
Hapa A et al. | Childhood pityriasis lichenoides and oral erythromycin. | 2012 Nov-Dec | Pediatr Dermatol | pmid:22639857 |
Asai N et al. | A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. | 2012 Nov-Dec | J Bras Pneumol | pmid:23288130 |
Clementson B and Smidt AC | Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. | 2012 May-Jun | Pediatr Dermatol | pmid:22122785 |
Kuhn M et al. | Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. | 2012 Jul-Aug | Berl. Munch. Tierarztl. Wochenschr. | pmid:22919930 |
Jiang RS et al. | Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. | 2012 Jul-Aug | Am J Rhinol Allergy | pmid:22801017 |
Kuehne SA and Minton NP | ClosTron-mediated engineering of Clostridium. | 2012 Jul-Aug | Bioengineered | pmid:22750794 |
Miguel AI et al. | Pediatric ocular rosacea: 2 cases. | 2012 Jul-Aug | Eur J Ophthalmol | pmid:22267454 |
Amatya A et al. | Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. | 2012 Jan-Mar | Kathmandu Univ Med J (KUMJ) | pmid:22971864 |
Zhang H et al. | Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. | 2012 Jan-Feb | Biotechnol. Prog. | pmid:21905273 |
Pehr K | Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. | 2012 Jan-Feb | J Cutan Med Surg | pmid:22417996 |
Zou X et al. | Real-time fluid dynamics investigation and physiological response for erythromycin fermentation scale-up from 50 L to 132 m3 fermenter. | 2012 | Bioprocess Biosyst Eng | pmid:22139481 |
Fischer H et al. | In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. | 2012 | J. Med. Chem. | pmid:22122484 |
Krasniqi S et al. | Blood, tissue, and intracellular concentrations of erythromycin and its metabolite anhydroerythromycin during and after therapy. | 2012 | Antimicrob. Agents Chemother. | pmid:22083477 |
Perić M et al. | Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin. | 2012 | J. Med. Chem. | pmid:22148880 |
Reil M et al. | Seasonality of Clostridium difficile infections in Southern Germany. | 2012 | Epidemiol. Infect. | pmid:22152928 |
Kumar R et al. | Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22153939 |
Osman KM et al. | Antimicrobial susceptibility and molecular typing of multiple Chlamydiaceae species isolated from genital infection of women in Egypt. | 2012 | Microb. Drug Resist. | pmid:22455539 |
Marlow N et al. | Characteristics of children with cerebral palsy in the ORACLE children study. | 2012 | Dev Med Child Neurol | pmid:22458348 |
Romøren M et al. | Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway. | 2012 | Br J Clin Pharmacol | pmid:22463376 |
Lialikov SA et al. | [Monitoring of side effects and estimation of cycloferon efficacy in treatment of children with frequent and prolonged diseases]. | 2012 | Antibiot. Khimioter. | pmid:23700934 |
Laurens C et al. | Clinical and antimicrobial susceptibility data of 140 Streptococcus pseudopneumoniae isolates in France. | 2012 | Antimicrob. Agents Chemother. | pmid:22644030 |
Thumu SC and Halami PM | Presence of erythromycin and tetracycline resistance genes in lactic acid bacteria from fermented foods of Indian origin. | 2012 | Antonie Van Leeuwenhoek | pmid:22644346 |
Sui Q et al. | Identification of priority pharmaceuticals in the water environment of China. | 2012 | Chemosphere | pmid:22591850 |
Constable PD et al. | Evidence-based use of prokinetic drugs for abomasal disorders in cattle. | 2012 | Vet. Clin. North Am. Food Anim. Pract. | pmid:22374117 |
Chuang CC et al. | Staphylococcus aureus ocular infection: methicillin-resistance, clinical features, and antibiotic susceptibilities. | 2012 | PLoS ONE | pmid:22880135 |
Block SL | Etiologic and therapeutic pitfalls of newborn conjunctivitis. | 2012 | Pediatr Ann | pmid:22881420 |
Pinto A et al. | 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. | 2012 | Org. Lett. | pmid:22519860 |
Rocco L et al. | Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. | 2012 | Environ. Toxicol. | pmid:21384490 |
Smith EM et al. | In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes. | 2012 | Aquat. Toxicol. | pmid:22000335 |
Mercer BM et al. | The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. | 2012 | Am. J. Obstet. Gynecol. | pmid:22000668 |
Pendela M et al. | Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. | 2012 | Anal Bioanal Chem | pmid:22002558 |
Lu S and Zgurskaya HI | Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter. | 2012 | Mol. Microbiol. | pmid:23057817 |
Parhi A et al. | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23058886 |
Wilson BB et al. | An atypical presentation of erythrasma. | 2012 | J. Am. Acad. Dermatol. | pmid:23062922 |
Zhou L et al. | Molecular characteristics of erythromycin-resistant Streptococcus pneumoniae from pediatric patients younger than five years in Beijing, 2010. | 2012 | BMC Microbiol. | pmid:23043378 |
Lancaster CS et al. | OATP1B1 polymorphism as a determinant of erythromycin disposition. | 2012 | Clin. Pharmacol. Ther. | pmid:22990751 |
Rubio-López V et al. | Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994-2006). | 2012 | BMC Microbiol. | pmid:22998619 |
Marks LR et al. | The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents. | 2012 | PLoS ONE | pmid:22905269 |
Weisman LE et al. | Appropriate antibiotic therapy improves Ureaplasma sepsis outcome in the neonatal mouse. | 2012 | Pediatr. Res. | pmid:22907617 |