erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zou X et al. | Real-time fluid dynamics investigation and physiological response for erythromycin fermentation scale-up from 50 L to 132 m3 fermenter. | 2012 | Bioprocess Biosyst Eng | pmid:22139481 |
| Fischer H et al. | In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. | 2012 | J. Med. Chem. | pmid:22122484 |
| Perić M et al. | Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin. | 2012 | J. Med. Chem. | pmid:22148880 |
| Reil M et al. | Seasonality of Clostridium difficile infections in Southern Germany. | 2012 | Epidemiol. Infect. | pmid:22152928 |
| Osman KM et al. | Antimicrobial susceptibility and molecular typing of multiple Chlamydiaceae species isolated from genital infection of women in Egypt. | 2012 | Microb. Drug Resist. | pmid:22455539 |
| Marlow N et al. | Characteristics of children with cerebral palsy in the ORACLE children study. | 2012 | Dev Med Child Neurol | pmid:22458348 |
| Lialikov SA et al. | [Monitoring of side effects and estimation of cycloferon efficacy in treatment of children with frequent and prolonged diseases]. | 2012 | Antibiot. Khimioter. | pmid:23700934 |
| Teodoro CR et al. | Characterization of MLS(b) resistance among Staphylococcus aureus and Staphylococcus epidermidis isolates carrying different SCCmec types. | 2012 | Microbiol. Immunol. | pmid:22672011 |
| Laurens C et al. | Clinical and antimicrobial susceptibility data of 140 Streptococcus pseudopneumoniae isolates in France. | 2012 | Antimicrob. Agents Chemother. | pmid:22644030 |
| Thumu SC and Halami PM | Presence of erythromycin and tetracycline resistance genes in lactic acid bacteria from fermented foods of Indian origin. | 2012 | Antonie Van Leeuwenhoek | pmid:22644346 |
| Chuang CC et al. | Staphylococcus aureus ocular infection: methicillin-resistance, clinical features, and antibiotic susceptibilities. | 2012 | PLoS ONE | pmid:22880135 |
| Block SL | Etiologic and therapeutic pitfalls of newborn conjunctivitis. | 2012 | Pediatr Ann | pmid:22881420 |
| Nelson CG and Burke TR | Samarium iodide-mediated Reformatsky reactions for the stereoselective preparation of β-hydroxy-γ-amino acids: synthesis of isostatine and dolaisoleucine. | 2012 | J. Org. Chem. | pmid:22136325 |
| Zhou X et al. | Marthiapeptide A, an anti-infective and cytotoxic polythiazole cyclopeptide from a 60 L scale fermentation of the deep sea-derived Marinactinospora thermotolerans SCSIO 00652. | 2012 | J. Nat. Prod. | pmid:23215246 |
| Rocco L et al. | Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. | 2012 | Environ. Toxicol. | pmid:21384490 |
| Smith EM et al. | In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes. | 2012 | Aquat. Toxicol. | pmid:22000335 |
| Lu S and Zgurskaya HI | Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter. | 2012 | Mol. Microbiol. | pmid:23057817 |
| Parhi A et al. | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23058886 |
| Lancaster CS et al. | OATP1B1 polymorphism as a determinant of erythromycin disposition. | 2012 | Clin. Pharmacol. Ther. | pmid:22990751 |
| Rubio-López V et al. | Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994-2006). | 2012 | BMC Microbiol. | pmid:22998619 |
| Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
| Ezhova NM et al. | [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. | 2011 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:22288199 |
| Nielsen EI et al. | Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. | 2011 | Antimicrob. Agents Chemother. | pmid:21282424 |
| Belousoff MJ et al. | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21282615 |
| Yuan H et al. | [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. | 2011 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:22041779 |
| Spigaglia P et al. | Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. | 2011 | Emerging Infect. Dis. | pmid:21291621 |
| Huppertz A et al. | Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). | 2011 | J Magn Reson Imaging | pmid:21274983 |
| Watanabe I et al. | Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block. | 2011 | Int Heart J | pmid:22188715 |
| RodrÃguez C et al. | [Resistance phenotypes and genotypes of Streptococcus pyogenes clinical isolates in Chile over a 10-year period]. | 2011 | Rev Med Chil | pmid:22215392 |
| Tazi A et al. | Invasive group B streptococcal infections in adults, France (2007-2010). | 2011 | Clin. Microbiol. Infect. | pmid:21883671 |
| Fenoll A et al. | Increase in serotype 19A prevalence and amoxicillin non-susceptibility among paediatric Streptococcus pneumoniae isolates from middle ear fluid in a passive laboratory-based surveillance in Spain, 1997-2009. | 2011 | BMC Infect. Dis. | pmid:21910891 |
| Maezono H et al. | Antibiofilm effects of azithromycin and erythromycin on Porphyromonas gingivalis. | 2011 | Antimicrob. Agents Chemother. | pmid:21911560 |
| Sigaroudinia MO and Quayle AR | Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. | 2011 | Surgeon | pmid:21550524 |
| Lehtopolku M et al. | Ribosomal mutations as the main cause of macrolide resistance in Campylobacter jejuni and Campylobacter coli. | 2011 | Antimicrob. Agents Chemother. | pmid:21911571 |
| Szary NM et al. | Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. | 2011 | Scand. J. Gastroenterol. | pmid:21561232 |
| Tanamachi C et al. | [A case of Desulfovibrio desulfuricans cultured from blood in Japan]. | 2011 | Rinsho Byori | pmid:21706860 |
| Mikura S et al. | Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. | 2011 | Transl Res | pmid:21708354 |
| Richter SS et al. | Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. | 2011 | Antimicrob. Agents Chemother. | pmid:21709080 |
| Muruganathan G et al. | Interaction study of moxifloxacin and lomefloxacin with co-administered drugs. | 2011 | Pak J Pharm Sci | pmid:21715267 |
| Panigaj M et al. | Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. | 2011 | PLoS ONE | pmid:21912705 |
| Maragno AL et al. | ISG15 modulates development of the erythroid lineage. | 2011 | PLoS ONE | pmid:22022510 |
| Kreft A et al. | JAK2-V617F-mutated myeloproliferative neoplasms reveal different allele burden within hematopoietic cell lineages: a microdissection study of bone marrow trephine biopsies. | 2011 | Virchows Arch. | pmid:22006129 |
| Zaed AM and Sutherland A | Total synthesis of clavaminol A, C and H. | 2011 | Org. Biomol. Chem. | pmid:21879135 |
| Taillon MP et al. | Potentially new isobaric metabolite of fluvastatin observed by LC-MS/MS during incurred sample analysis. | 2011 | Bioanalysis | pmid:21877892 |
| Pignatello R et al. | Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. | 2011 | AAPS PharmSciTech | pmid:21479751 |
| Keelan JA et al. | Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. | 2011 | Am. J. Obstet. Gynecol. | pmid:21481833 |
| Fan C and He J | Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. | 2011 | Water Res. | pmid:21482429 |
| Franke RM et al. | Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. | 2011 | Clin. Pharmacol. Ther. | pmid:21451505 |
| Li Y et al. | Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. | 2011 | J. Appl. Microbiol. | pmid:20961364 |
| Vuppalanchi R et al. | Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. | 2011 | J. Clin. Gastroenterol. | pmid:20962670 |