erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Komiyane M and Tamaoki K | [Clinical effects of macrolides on psoriasis vulgaris]. | 2000 | Jpn J Antibiot | pmid:10756468 |
| Dezaki S et al. | [Effects of macrolides on several transcription factors]. | 2000 | Jpn J Antibiot | pmid:10756462 |
| Takahashi T et al. | [Efficacy of erythromycin (EM) on a rabbit model of Pseudomonas aeruginosa-induced chronic bronchiolitis--its action on apoptosis]. | 2000 | Jpn J Antibiot | pmid:10756461 |
| Obori M et al. | [Effects of 14-member cyclic macrolide compounds on rat leukocyte chemotaxis]. | 2000 | Jpn J Antibiot | pmid:10756460 |
| Enomoto F et al. | [Involvement of adhesion molecules in experimental otitis media in rats--an in vitro evaluation]. | 2000 | Jpn J Antibiot | pmid:10756459 |
| Miyazawa T and Iino Y | [Effect of macrolides on ligand expression by T lymphocytes obtained from human peripheral blood]. | 2000 | Jpn J Antibiot | pmid:10756457 |
| Sakamoto M et al. | [Usefulness of clarithromycin in paitents with unresectable non-small-cell lung cancer--clinical evaluation of those who survived for a long time and those succumbed in a short period]. | 2000 | Jpn J Antibiot | pmid:10756453 |
| Homa K et al. | [Erythromycin sensitivity of Shigella flexneri and S. sonnei]. | 2000 | Jpn J Antibiot | pmid:10756447 |
| Nakamura A et al. | [Selective suppression of aminoglycoside 3'-phosphorylating enzyme activities by macrolides--a study by using macrolide-resistant bacteria]. | 2000 | Jpn J Antibiot | pmid:10756446 |
| Cho T et al. | [Effects of EM on the intracellular Ca 2+ response in A549 cells]. | 2000 | Jpn J Antibiot | pmid:10756443 |
| Nakaya Y et al. | [Suppressive action of erythromycin on cultured tracheal epithelial cell chloride channel activated by interferon-gamma]. | 2000 | Jpn J Antibiot | pmid:10756442 |
| Majima Y et al. | [Study on a rat tracheal mucus producing model]. | 2000 | Jpn J Antibiot | pmid:10756441 |
| Bassetti M et al. | Erythromycin resistance in Streptococcus pyogenes in Italy. | 2000 Mar-Apr | Emerging Infect. Dis. | pmid:10756153 |
| Stamm LV and Bergen HL | A point mutation associated with bacterial macrolide resistance is present in both 23S rRNA genes of an erythromycin-resistant Treponema pallidum clinical isolate. | 2000 | Antimicrob. Agents Chemother. | pmid:10755994 |
| Bellaïche G et al. | [Non-hemorrhagic and erythematous colitis associated with Klebsiella oxytoca after treatment with erythromycin]. | 2000 | Gastroenterol. Clin. Biol. | pmid:10755860 |
| Brenciaglia MI et al. | Helicobacter pylori: cultivability and antibiotic susceptibility of coccoid forms. | 2000 | Int. J. Antimicrob. Agents | pmid:10755237 |
| Petrakis IE et al. | Induced-hyperglycemia attenuates erythromycin-induced acceleration of hypertonic liquid-phase gastric emptying in type-I diabetic patients. | 1999 | Dig Dis | pmid:10754365 |
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| Zhao DM et al. | Effect of erythromycin on ATP-induced intracellular calcium response in A549 cells. | 2000 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:10749750 |
| Hoppe JE | Neonatal pertussis. | 2000 | Pediatr. Infect. Dis. J. | pmid:10749468 |
| Faure C et al. | Effect of meal and intravenous erythromycin on manometric and electrogastrographic measurements of gastric motor and electrical activity. | 2000 | Dig. Dis. Sci. | pmid:10749328 |
| Furneri PM et al. | Genetic basis of natural resistance to erythromycin in Mycoplasma hominis. | 2000 | J. Antimicrob. Chemother. | pmid:10747837 |
| Luna VA et al. | A novel multiresistant Streptococcus pneumoniae serogroup 19 clone from Washington State identified by pulsed-field gel electrophoresis and restriction fragment length patterns. | 2000 | J. Clin. Microbiol. | pmid:10747146 |
| Davies TA et al. | Antipneumococcal activity of telithromycin by agar dilution, microdilution, E test, and disk diffusion methodologies. | 2000 | J. Clin. Microbiol. | pmid:10747123 |
| Martinez JA et al. | Diffuse panbronchiolitis in Latin America. | 2000 | Am. J. Med. Sci. | pmid:10746829 |
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| Orrett FA | Methicillin resistance among Trinidadian isolates of community and hospital strains of Staphylococcus aureus and their patterns of resistance to non-beta-lactam antibiotics. | 1999 | Jpn. J. Infect. Dis. | pmid:10738361 |
| Or YS et al. | Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens. | 2000 | J. Med. Chem. | pmid:10737737 |
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| Smith AJ et al. | Prokinetic effect of erythromycin after colorectal surgery: randomized, placebo-controlled, double-blind study. | 2000 | Dis. Colon Rectum | pmid:10733114 |
| Gracey HE et al. | Preparation and in vitro antibacterial activity of 6-O-methylerythromycin D. | 1999 | J. Antibiot. | pmid:10726932 |
| Strigl S et al. | In vitro activity of ABT 773, a new ketolide antibiotic, against Chlamydia pneumoniae. | 2000 | Antimicrob. Agents Chemother. | pmid:10722526 |
| Ono T et al. | Susceptibilities of oral and nasal isolates of Streptococcus mitis and Streptococcus oralis to macrolides and PCR detection of resistance genes. | 2000 | Antimicrob. Agents Chemother. | pmid:10722517 |
| Brophy DF et al. | Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteers. | 2000 | Antimicrob. Agents Chemother. | pmid:10722500 |
| Portillo A et al. | Macrolide resistance genes in Enterococcus spp. | 2000 | Antimicrob. Agents Chemother. | pmid:10722498 |
| Chepkwony HK et al. | Separation of erythromycin and related substances on base-deactivated reversed-phase silica gel columns. | 2000 | J Chromatogr A | pmid:10722081 |
| López de Blanc S et al. | Bacillary angiomatosis affecting the oral cavity. Report of two cases and review. | 2000 | J. Oral Pathol. Med. | pmid:10718405 |
| Dewan NA et al. | Acute exacerbation of COPD: factors associated with poor treatment outcome. | 2000 | Chest | pmid:10712989 |
| Moussa F et al. | Erythromycin eye ointment: effect on gastrointestinal motility. | 2000 | Am. J. Gastroenterol. | pmid:10710093 |
| Krecic-Shepard ME et al. | Gender-specific effects on verapamil pharmacokinetics and pharmacodynamics in humans. | 2000 | J Clin Pharmacol | pmid:10709150 |
| MacLaren R et al. | Sequential single doses of cisapride, erythromycin, and metoclopramide in critically ill patients intolerant to enteral nutrition: a randomized, placebo-controlled, crossover study. | 2000 | Crit. Care Med. | pmid:10708180 |
| Sazykin IuO et al. | [Ketolides--erythromycin derivatives with activity against macrolide-resistant bacteria]. | 2000 | Antibiot. Khimioter. | pmid:10707799 |
| Karam B et al. | Ergotism precipitated by erythromycin: a rare case of vasospasm. | 2000 | Eur J Vasc Endovasc Surg | pmid:10706847 |
| Faoagali JL et al. | Sensitivity of 941 beta haemolytic streptococci to antibacterial drugs. | 1976 | N. Z. Med. J. | pmid:1070586 |