erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lakritz J et al. | Comparison of microbiologic and high-performance liquid chromatography assays to determine plasma concentrations, pharmacokinetics, and bioavailability of erythromycin base in plasma of foals after intravenous or intragastric administration. | 1999 | Am. J. Vet. Res. | pmid:10211682 |
| McConnell SA and Amsden GW | Review and comparison of advanced-generation macrolides clarithromycin and dirithromycin. | 1999 | Pharmacotherapy | pmid:10212011 |
| Betriu C et al. | Incidence of erythromycin resistance in Streptococcus pyogenes: a 10-year study. | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10212752 |
| Dubois J and St-Pierre C | In vitro activity of gatifloxacin, compared with ciprofloxacin, clarithromycin, erythromycin, and rifampin, against Legionella species. | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10212753 |
| Biedenbach DJ et al. | Comparative in vitro evaluation of dirithromycin tested against recent clinical isolates of Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae, including effects of medium supplements and test conditions on MIC results. | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10212755 |
| Kim RB et al. | Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. | 1999 | Pharm. Res. | pmid:10213372 |
| Torii A | [Effective treatment in combination with erythromycin and cisapride for chronic idiopathic intestinal pseudo-obstruction (CIIP)]. | 1999 | Nihon Shokakibyo Gakkai Zasshi | pmid:10214084 |
| Bercault N and Linassier P | [The value of sepsis isolation to diminish the spread of multidrug-resistant bacteria in intensive care. Consequences on the incidence of nosocomial infections]. | 1999 | Rev Med Interne | pmid:10220829 |
| Perez-Trallero E et al. | Clonal differences among erythromycin-resistant Streptococcus pyogenes in Spain. | 1999 Mar-Apr | Emerging Infect. Dis. | pmid:10221875 |
| Jackson LA et al. | Lack of association between first myocardial infarction and past use of erythromycin, tetracycline, or doxycycline. | 1999 Mar-Apr | Emerging Infect. Dis. | pmid:10221884 |
| Bassetti M et al. | Streptococcus pyogenes erythromycin resistance in Italy. | 1999 Mar-Apr | Emerging Infect. Dis. | pmid:10221991 |
| Siedlik PH et al. | Erythromycin coadministration increases plasma atorvastatin concentrations. | 1999 | J Clin Pharmacol | pmid:10234598 |
| Tran JQ et al. | Assessment of the potential pharmacokinetic and pharmacodynamic interactions between erythromycin and argatroban. | 1999 | J Clin Pharmacol | pmid:10234600 |
| Morris LA and Kanouse DE | Consumer reactions to differing amounts of written drug information. | 1980 Jul-Aug | Drug Intell Clin Pharm | pmid:10247887 |
| Bystedt H et al. | Concentrations of azidocillin, erythromycin, doxycycline and clindamycin in human mandibular bone. | 1978 | Int J Oral Surg | pmid:102599 |
| Klein JO | Middle ear disease in children. | 1976 | Hosp Pract | pmid:1026633 |
| Gregotti C et al. | [Effects of phenobarbital on the hepatic microsome metabolism of erythromycin in rats]. | 1976 | Boll. Soc. Ital. Biol. Sper. | pmid:1027460 |
| Melon J and Reginster M | [Passage into normal salivary, lacrimal and nasal secretions of ampicillin and erythromycin administered intramuscularly]. | 1976 | Acta Otorhinolaryngol Belg | pmid:1028340 |
| Rosenthal AL et al. | Polyacrylic bone cement containing erythromycin and colistin. I. In vitro bacteriological activity and diffusion properties of erythromycin, colistin and erythromycin/colistin comibination. | 1976 | J. Int. Med. Res. | pmid:1028631 |
| Stille W | [Legionnaire's disease]. | 1978 | MMW Munch Med Wochenschr | pmid:102952 |