erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lazarevski G et al. | Acid catalyzed ring opening reactions of 6-deoxy-9-deoxo-9a-aza-9a-homo-erythromycin A 6,9-cyclic imino ether. | 1998 | J. Antibiot. | pmid:9820243 |
| Takano M et al. | Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells. | 1998 | Eur. J. Pharmacol. | pmid:9822896 |
| Moffitt CM | Field trials of investigational new animal drugs. | 1998 | Vet Hum Toxicol | pmid:9823586 |
| Su BH et al. | Effect of erythromycin on feeding intolerance in very low birth weight infants: a preliminary observation. | 1998 Sep-Oct | Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi | pmid:9823678 |
| Xu QW et al. | Altered migrating myoelectrical complex in an animal model of cholesterol gallstone disease: the effect of erythromycin. | 1998 | Gut | pmid:9824610 |
| Thomsen MS et al. | Lack of pharmacokinetic interaction between tiagabine and erythromycin. | 1998 | J Clin Pharmacol | pmid:9824787 |
| Jónsson B et al. | Ureaplasma urealyticum, erythromycin and respiratory morbidity in high-risk preterm neonates. | 1998 | Acta Paediatr. | pmid:9825977 |
| Larsen B and Glover DD | Serum erythromycin levels in pregnancy. | 1998 Sep-Oct | Clin Ther | pmid:9829448 |
| Sato K et al. | Comparison of the anticoagulant and antithrombotic effects of YM-75466, a novel orally-active factor Xa inhibitor, and warfarin in mice. | 1998 | Jpn. J. Pharmacol. | pmid:9829622 |
| Woodhead M | Community acquired pneumonia in elderly people. Addition of erythromycin is not currently justified. | 1998 | BMJ | pmid:9831595 |
| Reinert RR et al. | In vitro activity of quinupristin/dalfopristin against erythromycin-susceptible and erythromycin-resistant Streptococcus pneumoniae. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9832271 |
| Isohanni MH et al. | Effect of erythromycin and itraconazole on the pharmacokinetics of intravenous lignocaine. | 1998 | Eur. J. Clin. Pharmacol. | pmid:9832299 |
| Khiat A and Boulanger Y | Identification of the motilide pharmacophores using quantitative structure activity relationships. | 1998 | J. Pept. Res. | pmid:9832311 |
| Nissan A et al. | Direct inhibitory effect of erythromycin on the gallbladder muscle. | 1997 Jul-Aug | J. Gastrointest. Surg. | pmid:9834366 |
| Baltch AL et al. | Antibacterial effects of levofloxacin, erythromycin, and rifampin in a human monocyte system against Legionella pneumophila. | 1998 | Antimicrob. Agents Chemother. | pmid:9835507 |
| Berry V et al. | Bacteriological efficacies of three macrolides compared with those of amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae. | 1998 | Antimicrob. Agents Chemother. | pmid:9835514 |
| Torres C et al. | In vitro activity of the new ketolide HMR3647 in comparison with those of macrolides and pristinamycins against Enterococcus spp. | 1998 | Antimicrob. Agents Chemother. | pmid:9835527 |
| Emond E et al. | AbiQ, an abortive infection mechanism from Lactococcus lactis. | 1998 | Appl. Environ. Microbiol. | pmid:9835558 |
| Kinashi H et al. | Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9836424 |
| Koh TH et al. | Molecular typing of multiresistant Streptococcus pneumoniae serogroup 19 in Singapore. | 1998 | Pathology | pmid:9839316 |