erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Shipley A et al. | T-strain mycoplasmas in non-specific urethritis. | 1968 | Med. J. Aust. | pmid:4872365 |
MosiÄchuk NM | [Permeability of the hemato-encephalic barrier to antibiotics in patients with infectious meningitis]. | 1968 | Zh Nevropatol Psikhiatr Im S S Korsakova | pmid:4872691 |
Aoki Y | Colicin type, biochemical type and drug-resistance pattern of Shigella sonnei isolated in Japan and its neighboring countries. | 1968 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:4874474 |
Ross S | Erythromycin, oleandomycin and triacetyloleandomycin. | 1968 | Pediatr. Clin. North Am. | pmid:4867776 |
Mao JC and Putterman M | Accumulation in gram-postive and gram-negative bacteria as a mechanism of resistance to erythromycin. | 1968 | J. Bacteriol. | pmid:4966821 |
Ferrando R | [Absorption and metabolism of antibiotics. Residues in the tissues]. | 1968 | Bibl Nutr Dieta | pmid:4868400 |
Frisby BR | A laboratory comparison of tri-acetyl oleandomycin and nine other antibiotics. | 1968 | Med. J. Aust. | pmid:4967052 |
Lindsay AE and Truxal AC | Oral therapy in bacterial endocarditis. | 1968 | Rocky Mt Med J | pmid:4967211 |
Oleinick NL et al. | Nonidentity of the site of action of erythromycin A and chloramphenicol on Bacillus subtilis ribosomes. | 1968 | Biochim. Biophys. Acta | pmid:4967315 |
Osman HG et al. | Utilization of Egyptian raw by-products for the erythromycin production by Streptomyces erythreus. | 1968 | Z. Allg. Mikrobiol. | pmid:4989340 |
Henriksen SD and Bovre K | Moraxella kingii sp.nov., a haemolytic, saccharolytic species of the genus Moraxella. | 1968 | J. Gen. Microbiol. | pmid:5185818 |
Choudhuri KK and Basu Mallick KC | Study of antibiotic-resistant staphylococci isolated from different sources and their role in pathogenicity. | 1968 | Indian J. Med. Res. | pmid:5186305 |
Robertson MH | Tetracycline-resistant streptococci in South-west Essex: a continuing survey. | 1968 | Br Med J | pmid:5186976 |
Sabath LD et al. | Enhancing effect on alkalinization of the medium on the activity of erythromycin against gram-negative bacteria. | 1968 | Appl Microbiol | pmid:4970991 |
Jewett JF et al. | Childbed fever--a continuing entity. | 1968 | JAMA | pmid:4971028 |
Iats'ko VA | [On the dynamics of sensitivity to antibiotics of different microorganisms, isolated from patients of a surgical section]. | 1968 | Antibiotiki | pmid:4971186 |
Betinová M | [Effect of tetracyclines, macrolide antibiotics, and sigmamycin on staphylococci in vitro]. | 1968 | Biologia | pmid:4971503 |
Erythromycin compared with phenoxymethyl-penicillin and tetracycline. | 1968 | Practitioner | pmid:4972106 | |
Ahmed A | Altered ribosomes in spiramycin-resistant mutants of Bacillus subtilis. | 1968 | Biochim. Biophys. Acta | pmid:4972350 |
Ramos e Silva J | [Current treatment of syphilis, particularly of early syphilis]. | 1968 | Rev Bras Med | pmid:5707186 |
Hejzlar M et al. | Ten-year study of Neisseria gonorrhoeae sensitivity to antibiotics in Czechoslovakia. | 1968 | J Hyg Epidemiol Microbiol Immunol | pmid:4977454 |
Ocklitz HW et al. | [Pediatric guidelines. 3. Antibiotics--indications]. | 1968 | Z Arztl Fortbild (Jena) | pmid:4978334 |
Paterson PY and Madden GM | Occurrence and erythromycin susceptibility of penicillin-resistant Viridans streptococci in rheumatic fever patients on oral penicillin prophylaxis. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735376 |
McGehee RF R et al. | Resistance of Staphylococcus aureus to lincomycin, clinimycin, and erythromycin. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735385 |
Wick WE and Mallett GE | New analysis for the therapeutic efficacy opropionyl erythromycin and erythromycin base. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735386 |
Kuntsevich LD | [Erythromycin and oleandomycin in therapy of fresh gonorrhea in women]. | 1968 | Vestn Dermatol Venerol | pmid:5738081 |
Pezzìca R | [Damage caused by associated antibiotics in domiciliary therapy of acute febrile diseases. Film: "These 3 neutrophil leukocytes are from a 4-year-old child on the fourth day of treatment with CAF in average therapeutic doses. The toxic granulations in the protoplasm are clearly visible"]. | 1968 | Minerva Pediatr. | pmid:5739033 |
Mozziconacci P and Attal C | [Treatment of rheumatic cardiopathies]. | 1968 | Sem Hop | pmid:4307324 |
Renzini G et al. | [Study of the antibacterial activity and of the serum and tissue levels produced in animals by the administration of two antibiotic associations]. | 1968 | Antibiotica | pmid:5740898 |
Studnitsin AA and Pashkov BM | [Results of discussions on the treatment of syphilis]. | 1968 | Vestn Dermatol Venerol | pmid:5742374 |
Martini J et al. | [Treatment of acute male gonococcal urethritis with a single dosis of erythromycin-stearate]. | 1968 | Rev Med Chil | pmid:5746282 |
Mitsui Y and Suzuki H | [Evaluation of colistin-erythromycin ointment and solution in ophthalmology]. | 1968 | Nihon Ganka Kiyo | pmid:5748900 |
Amato Neto V and Wanderley RA | [Use of an erythromycin stearate preparation, of regulated intestinal release in the treatment of intestinal amebiasis]. | 1968 | Hospital (Rio J) | pmid:5311770 |
Jayaraman J and Goldberg IH | Localization of sparsomycin action to the peptide-bond-forming step. | 1968 | Biochemistry | pmid:4921281 |
Herrschaft H | [On the participation of the central nervous system in Behcet's disease]. | 1968 | Dtsch. Med. Wochenschr. | pmid:5655850 |
Biró L and Iván E | Study of bactericidal and bacteriostatic antibiotics in animals with normal and suppressed immunity. | 1968 | Chemotherapy | pmid:5656115 |
Wyman JB et al. | Pancreatic, hepatic, and renal excretion of antibiotics in dogs. Observations on erythromycin, lincomycin, kanamycin, and colistimethate excretion. | 1968 | Arch Surg | pmid:5657416 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. 3. Occurrence and spread of "type 6557", with special reference to the consumption of some antibiotics. | 1968 | Acta Pathol Microbiol Scand | pmid:4244485 |
Arret B and Eckert J | New developments in antibiotic interference thresholds of microbial assays. | 1968 | J Pharm Sci | pmid:4297949 |
Winningham DG et al. | Diffusion of antibiotics from plasma into prostatic fluid. | 1968 | Nature | pmid:4298194 |
Tereshin IM and Belousova II | [Effect of some antibiotics on the transfer of the resistance to tetracycline and chloramphenicol by means of the episome factor (Rtf)]. | 1968 | Antibiotiki | pmid:4298603 |
Sabath LD et al. | Serum glutamic oxalacetic transaminase. False elevations during administration of erythromycin. | 1968 | N. Engl. J. Med. | pmid:5686481 |
Grimble AS | Possible Mycoplasma hominis urethritis rvealed by differing responses of "abacterial urethritis" to treatment with tetracycline and erythromycin. | 1968 | Br J Vener Dis | pmid:5687045 |
Dohlman CH and Boruchoff SA | Penetrating keratoplasty. | 1968 | Int Ophthalmol Clin | pmid:4904228 |
Molina Pasquel C et al. | [Treatment of intestinal amebiasis using erythromycin stearate of normal release with enteric coating (A-16535). Study of 13 cases. Preliminary report]. | 1967 Oct-Dec | Rev Invest Salud Publica | pmid:5618959 |
Evdoshchenko EA et al. | [Treatment of cochlear neuritis]. | 1967 May-Jun | Zh Ushn Nos Gorl Bolezn | pmid:5621389 |
Serene TP and Anderson DL | Isolation of mycoplasma from human root canals. | 1967 Mar-Apr | J. Dent. Res. | pmid:5228073 |
Timsit E | [Results obtained with erythromycin stearate in the treatment of acnes]. | 1967 Jun-Jul | Sem Ther | pmid:4240940 |
Teodorovici G et al. | [Evolution of the antibiotic sensitivity of pathogenic staphylococci isolated in rural areas]. | 1967 Jul-Sep | Rev Med Chir Soc Med Nat Iasi | pmid:5195743 |
ArcalÃs L and Caldés J | [Report on the antibiotic activity of the DAN-352 compound]. | 1967 Jul-Dec | Microbiol Esp | pmid:5619843 |
Rdzanek I and Weyman-Rzucidlo D | [Recent views on the etiology and therapy of erythrasma]. | 1967 Jan-Feb | Przegl Dermatol | pmid:6044676 |
Moro S | [In vitro sensitivity to antibiotics of spores of Plectridium tetani]. | 1967 Jan-Feb | G Batteriol Virol Immunol | pmid:4899675 |
Saslaw S and Carlisle HN | Studies on therapy of staphylococcal infections in monkeys. I. Comparison of cloxacillin, triacetyloleandomycin and erythromycin. | 1967 Aug-Sep | Proc. Soc. Exp. Biol. Med. | pmid:4962963 |
Afanas'ev BA | [Erythromycin in the treatment of gonorrhea in women]. | 1967 | Vestn Dermatol Venerol | pmid:5611849 |
Levitov MM and Brinberg SL | [Physiology of antibiotic-producing microorganisms and the process of biosynthesis of antibiotics]. | 1967 | Antibiotiki | pmid:4875265 |
Kuzel NR and Coffey HF | Automated analysis of erythromycin. | 1967 | J Pharm Sci | pmid:6034553 |
Richmond MH | A second regulatory region involved in penicillinase synthesis in Staphylococcus aureus. | 1967 | J. Mol. Biol. | pmid:6034780 |
Celmer WD and Ebringer L | Effects of certain O-acyl derivatives of oleandomycin and erythromycin on chloroplasts of Euglena gracilis. | 1967 | J. Protozool. | pmid:6038034 |
Perun TJ | Chemistry of erythronolide B. Acid-catalyzed transformations of the aglycone of erythromycin B. | 1967 | J. Org. Chem. | pmid:6046179 |
Djokić S and Tamburasĕv Z | Erythromycin study: 9-amino-3-O-cladinosyl-5-O-desosaminyl-6,11,12-tryhydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide. | 1967 | Tetrahedron Lett. | pmid:6047192 |
Martin JR and Rosenbrook W | Studies on the biosynthesis of the erythromycins. II. Isolation and structure of a biosynthetic intermediate, 6-deoxyerythronolide B. | 1967 | Biochemistry | pmid:6047629 |
Tourtellotte ME et al. | Protein synthesis in mycoplasma. | 1967 | Ann. N. Y. Acad. Sci. | pmid:5233752 |
Shepard MC | Cultivation and properties of T-strains of mycoplasma associated with nongonococcal urethritis. | 1967 | Ann. N. Y. Acad. Sci. | pmid:5233783 |
Stelińska A et al. | [Observations on the effectiveness of erythromycin activity on the bacterial flora of dental origin]. | 1967 | Czas Stomatol | pmid:5234368 |
Merklen FP and Renoux M | [Antibiotics other than penicillin in the treatment of syphilis]. | 1967 | Rev Fr Odontostomatol | pmid:5235420 |
Kalowski M and Romankiewicz GE | [Effect of penicillin and erythromycin on the inhibition of rampant dental caries in golden hamsters]. | 1967 | Czas Stomatol | pmid:5235543 |
Dechaume M et al. | [Clinical stomatologic studies of erythromycine stearate and erythromycine ethyl-succinate]. | 1967 | Inf Dent | pmid:5235751 |
Haraguchi I et al. | [Clinico-pathological study on the effect of erythromycin on pulp tissue]. | 1967 | Shikwa Gakuho | pmid:5236258 |
Takei M et al. | [Studies on the mixed culture of Candida and Lactobacillus. 3. Influences of the antibiotics (EM and TM)]. | 1967 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5236280 |
Molan PC and Hartles RL | The source of glycolytic activity in human saliva. | 1967 | Arch. Oral Biol. | pmid:5237340 |
Cernea P and Devien CV | [Therapeutic value of a new comined antibiotic therapy]. | 1967 | Rev Fr Odontostomatol | pmid:5238749 |
Dadswell JV | Bacteriological findings in acute otitis media. | 1967 | Lancet | pmid:4163147 |
Prokhorov BS | [Sensitivity to antibiotics and phagolytic properties of staphylococcal strains, isolated from patients]. | 1967 | Antibiotiki | pmid:5187281 |
Shneerson AN | [On the heterogenicity of the population of clinical strains of Staphylococci in relation to their sensitivity to polysynthetic penicillins and macrolide antibiotics]. | 1967 | Antibiotiki | pmid:5187299 |
Gutman LT et al. | Bacterial L-forms in relapsing urinary-tract infection. | 1967 | Lancet | pmid:4164065 |
Weisblum B | Pneumococcus resistant to erythromycin and lincomycin. | 1967 | Lancet | pmid:4164310 |
Jensen K | [Combination therapy with antibacterial chemotherapeutic agents in staphylococcal infections]. | 1967 | Ugeskr. Laeg. | pmid:5187979 |
Legler F | [Present resistance status of Staphylococcus aureus under specific consideration of the antibiotics virgimycia, cephalothin and fusidic acid]. | 1967 | Arzneimittelforschung | pmid:4974419 |
Hejzlar M et al. | Cephaloridine. II. The effect of cephaloridine on experimental model infections. | 1967 | J Hyg Epidemiol Microbiol Immunol | pmid:5629908 |
Kaltiala EH et al. | Subchronic toxicity of some erythromycin compounds in rats. | 1967 | Acta Pharmacol Toxicol (Copenh) | pmid:5630681 |
Larson RH et al. | The interaction of diet and microflora in experimental caries in the rat. | 1967 | Arch. Oral Biol. | pmid:5228613 |
Novick R | Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. | 1967 | Virology | pmid:4227577 |
Lucas JB and Price EV | Co-operative evaluation of treatment for early syphilis. Preliminary report with special reference to spectinomycin sulphate (actinospectacin). | 1967 | Br J Vener Dis | pmid:4230278 |
Hughes WT and Wan RT | Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. | 1967 | Am. J. Dis. Child. | pmid:4290285 |
Smits H and Freedman LR | Prolonged venous catheterization as a cause of sepsis. | 1967 | N. Engl. J. Med. | pmid:4290392 |
Halprin KM | Diagnosis with Wood's light. Tinea capitis and erythrasma. | 1967 | JAMA | pmid:6071300 |
Zegarelli EV et al. | Discoloration of the teeth in a 24-year-old patient with cystic fibrosis of the pancreas not primarily associated with tetracycline therapy. Report of a case. | 1967 | Oral Surg. Oral Med. Oral Pathol. | pmid:4291199 |
Williams ST | Sensitivity of streptomycetes to antibiotics as a taxonomic character. | 1967 | J. Gen. Microbiol. | pmid:4291590 |
Sterner G et al. | A comparative trial of cephaloridine and erythromycin in hospitalized pneumonic patients. | 1967 | Postgrad Med J | pmid:4861117 |
Smith CB et al. | Mycoplasma pneumoniae infections in volunteers. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4861142 |
Breitfellner G | [On the question of penicillin resistence]. | 1967 | Chemotherapy | pmid:4861270 |
Arai S et al. | Effect of antibiotics on the growth of various strains of Mycoplasma. | 1967 | J. Antibiot. | pmid:4170543 |
Kharitonova AM | [On the nephrotic action of antibiotics]. | 1967 | Antibiotiki | pmid:4171895 |
Medeiros J et al. | [A-16535 in the treatment of chronic intestinal amebiasis]. | 1967 | Hospital (Rio J) | pmid:5302541 |
Mehta BM et al. | Evidence of genetic transformation in Streptococcus faecium var. durans (SF-O). | 1967 | J. Bacteriol. | pmid:6051354 |
Chernomordik AB | [Synergistic action of antibiotics on Bacillus pyocianaeus]. | 1967 | Antibiotiki | pmid:4300088 |
Lantos J | Change in the phage type of Staphylococcus aureus as a result of lysogenizatio. | 1967 | Acta Microbiol Acad Sci Hung | pmid:4300285 |
DoutlÃk S et al. | Electroencephalographic changes after intravenous administration of antibiotics. | 1967 | Arzneimittelforschung | pmid:4300334 |
von Wasielewski E and Schütze E | [Treatment with antibiotic agents with special reference to their relation to otorhinolaryngology]. | 1967 | Arch Klin Exp Ohren Nasen Kehlkopfheilkd | pmid:4300371 |
Yousef RT et al. | An agar disc method for testing the sensitivity of microorganisms to antibiotics. | 1967 | Arzneimittelforschung | pmid:4303563 |