erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Liver Cirrhosis, Biliary D008105 12 associated lipids
Liver Diseases D008107 31 associated lipids
Long QT Syndrome D008133 10 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lyme Disease D008193 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Lymphangitis D008205 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Mycetoma D008271 4 associated lipids
Marfan Syndrome D008382 2 associated lipids
Mastoiditis D008417 2 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Megacolon D008531 1 associated lipids
Meningitis, Haemophilus D008583 3 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Microphthalmos D008850 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Multiple Myeloma D009101 13 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Myiasis D009198 1 associated lipids
Nasal Polyps D009298 26 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Nasopharyngitis D009304 2 associated lipids
Nausea D009325 7 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Nervous System Diseases D009422 37 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Neutropenia D009503 15 associated lipids
Nocardia Infections D009617 6 associated lipids
Obesity D009765 29 associated lipids
Endophthalmitis D009877 12 associated lipids
Ophthalmia Neonatorum D009878 1 associated lipids
Psittacosis D009956 4 associated lipids
Orthomyxoviridae Infections D009976 3 associated lipids
Osteitis D010000 10 associated lipids
Osteolysis D010014 8 associated lipids
Osteomyelitis D010019 10 associated lipids
Otitis D010031 5 associated lipids
Otitis Externa D010032 8 associated lipids
Otitis Media D010033 12 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Pain D010146 64 associated lipids
Pain, Postoperative D010149 13 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Pancreatitis D010195 10 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Parapsoriasis D010267 1 associated lipids
Paresthesia D010292 7 associated lipids
Parotitis D010309 4 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Peptic Ulcer Hemorrhage D010438 4 associated lipids
Periapical Diseases D010483 4 associated lipids
Pericarditis D010493 6 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Pericoronitis D010497 2 associated lipids
Periodontal Abscess D010508 2 associated lipids
Periodontitis D010518 22 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Pityriasis D010915 3 associated lipids
Pleural Diseases D010995 4 associated lipids
Pleural Effusion D010996 3 associated lipids
Pleurisy D010998 20 associated lipids
Pleuropneumonia D011001 3 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Pneumonia D011014 10 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Porphyrias D011164 2 associated lipids
Postgastrectomy Syndromes D011178 2 associated lipids
Prolapse D011391 1 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Prostatitis D011472 5 associated lipids
Protein-Losing Enteropathies D011504 2 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Psoriasis D011565 47 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Pulmonary Emphysema D011656 3 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Pyoderma D011711 5 associated lipids
Quadriplegia D011782 4 associated lipids
Radiodermatitis D011855 3 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Relapsing Fever D012061 3 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Rhinitis D012220 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Huang M et al. Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. 2015 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:26223917
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Takagi M et al. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. 2015 Drug Metab. Pharmacokinet. pmid:26195223
Aydin S et al. Development of antibiotic resistance genes in microbial communities during long-term operation of anaerobic reactors in the treatment of pharmaceutical wastewater. 2015 Water Res. pmid:26188597
Fayed B et al. Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. 2015 Appl. Environ. Microbiol. pmid:26431970
Wang L et al. Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. 2015 Lett. Appl. Microbiol. pmid:26031793
Wang Z et al. MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. 2015 PLoS ONE pmid:25706647
Yoon IA et al. Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. 2015 Int. J. Infect. Dis. pmid:26026823
Gherardi G et al. Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. 2015 Eur. J. Clin. Microbiol. Infect. Dis. pmid:26024763
Reveiz L and Cardona AF Antibiotics for acute laryngitis in adults. 2015 Cochrane Database Syst Rev pmid:26002823
Pesola AK et al. Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. 2015 Euro Surveill. pmid:25990232
Sun XJ et al. Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. 2015 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25957293
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Abreu AC et al. Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. 2015 Microb. Drug Resist. pmid:25734256
Ou H et al. Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. 2015 J. Hazard. Mater. pmid:25704432
Ikebe T et al. Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. 2015 Epidemiol. Infect. pmid:25703404
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Choi JH et al. Distribution of emm types among group A Streptococcus isolates from children in Korea. 2015 Diagn. Microbiol. Infect. Dis. pmid:25700867
Luo H et al. Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. 2015 Avian Pathol. pmid:25690020
Nagelreiter C et al. Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. 2015 Int J Pharm pmid:25475015
Harmer CJ et al. A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. 2015 J. Antimicrob. Chemother. pmid:25468903
Wan J et al. Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. 2015 J. Hazard. Mater. pmid:25464321
Zhou Z et al. Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. 2015 Antimicrob. Agents Chemother. pmid:25451048
Llorca M et al. Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. 2015 Chemosphere pmid:24972175
Yi X et al. Improved detection of multiple environmental antibiotics through an optimized sample extraction strategy in liquid chromatography-mass spectrometry analysis. 2015 Anal Bioanal Chem pmid:26449847
Ayazi P et al. Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. 2015 Prague Med Rep pmid:26445390
Yamaguchi M et al. Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. 2015 Cell Rep pmid:26440893
Chazan B et al. Susceptibility of Group A Streptococcus to Antimicrobial Agents in Northern Israel: A Surveillance Study. 2015 Microb. Drug Resist. pmid:26430943
Hoffmann K et al. Prevalence and resistance patterns of commensal S. aureus in community-dwelling GP patients and socio-demographic associations. A cross-sectional study in the framework of the APRES-project in Austria. 2015 BMC Infect. Dis. pmid:25981559
Banik A et al. Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital. 2015 J Infect Dev Ctries pmid:26230122
Wang Z et al. Direct Detection of Erythromycin-Resistant Bordetella pertussis in Clinical Specimens by PCR. 2015 J. Clin. Microbiol. pmid:26224847
Olivieri R et al. Evolution of macrolide resistance in Streptococcus pyogenes over 14 years in an area of central Italy. 2015 J. Med. Microbiol. pmid:26224594
Stieler AL et al. Macrolide-induced hyperthermia in foals: Role of impaired sweat responses. 2016 Equine Vet. J. pmid:26174202
Ulanovsky I et al. Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. 2016 Isr. Med. Assoc. J. pmid:28471562
Talebi M et al. Determination of Characteristics of Erythromycin Resistant Streptococcus pneumoniae with Preferred PCV Usage in Iran. 2016 PLoS ONE pmid:28033345
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Zmantar T et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. 2016 Microb. Pathog. pmid:27816681
Barbanti F and Spigaglia P Characterization of Clostridium difficile PCR-ribotype 018: A problematic emerging type. 2016 Anaerobe pmid:27725230
Mayor-Ibarguren A et al. Periorificial Lesions in a Young Girl. 2016 Actas Dermosifiliogr pmid:26935746
DeLorenzo ME et al. Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. 2016 Environ. Toxicol. pmid:25348372
Xu JY et al. Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. 2016 J. Proteome Res. pmid:27090497
Murchison L et al. Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. 2016 Pediatr. Surg. Int. pmid:27655365
Dzyubak E and Yap MN The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling. 2016 Antimicrob. Agents Chemother. pmid:27645242
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Jurado-Tarifa E et al. Genetic diversity and antimicrobial resistance of Campylobacter and Salmonella strains isolated from decoys and raptors. 2016 Comp. Immunol. Microbiol. Infect. Dis. pmid:27638115
Hu Z et al. Short-term performance of enhanced biological phosphorus removal (EBPR) system exposed to erythromycin (ERY) and oxytetracycline (OTC). 2016 Bioresour. Technol. pmid:27631889
Benamrouche N et al. Microbiological and molecular characterization of Corynebacterium diphtheriae isolated in Algeria between 1992 and 2015. 2016 Clin. Microbiol. Infect. pmid:27585941
Kang CH and So JS Antibiotic and heavy metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea, Korea. 2016 Mar. Pollut. Bull. pmid:27555484
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Choe YJ et al. Emergence of antibiotic-resistant non-vaccine serotype pneumococci in nasopharyngeal carriage in children after the use of extended-valency pneumococcal conjugate vaccines in Korea. 2016 Vaccine pmid:27546875
Kang CH et al. Antimicrobial susceptibility of Vibrio alginolyticus isolated from oyster in Korea. 2016 Environ Sci Pollut Res Int pmid:27543129
Metcalf BJ et al. Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States. 2016 Clin. Microbiol. Infect. pmid:27542334
Parasrampuria DA et al. Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. 2016 Br J Clin Pharmacol pmid:27530188
Ghosh S and Banerjee M Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus. 2016 Indian J. Med. Res. pmid:27241651
Pignatello R et al. Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. 2016 Eur J Med Chem pmid:27236014
Mushtaq A et al. Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva. 2016 Antimicrob. Agents Chemother. pmid:27216060
Hong M et al. Impacts of proline on the central metabolism of an industrial erythromycin-producing strain Saccharopolyspora erythraea via (13)C labeling experiments. 2016 J. Biotechnol. pmid:27215341
Stacevičienė I et al. Antibiotic resistance of Streptococcus pneumoniae, isolated from nasopharynx of preschool children with acute respiratory tract infection in Lithuania. 2016 BMC Infect. Dis. pmid:27206423
Tatiya-Aphiradee N et al. In vivo antibacterial activity of Garcinia mangostana pericarp extract against methicillin-resistant Staphylococcus aureus in a mouse superficial skin infection model. 2016 Pharm Biol pmid:27180784
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Patel MB et al. Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. 2016 Bioorg. Med. Chem. pmid:27166575
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Katayama Y et al. Neuroprotective effects of erythromycin on ischemic injury following permanent focal cerebral ischemia in rats. 2016 Neurol. Res. pmid:27078702
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Moltó-García B et al. Molecular characterization and antimicrobial susceptibility of hemolytic Streptococcus agalactiae from post-menopausal women. 2016 Maturitas pmid:26857873
Sari E et al. Fabrication of surface plasmon resonance nanosensor for the selective determination of erythromycin via molecular imprinted nanoparticles. 2016 Talanta pmid:26838449
Magnussen MD et al. Antibacterial resistance in Streptococcus pyogenes (GAS) from healthy carriers and tonsillitis patients and association with antibacterial sale in the Faroe Islands. 2016 APMIS pmid:26833774
Seki M et al. A Chronic Respiratory Pasteurella multocida Infection Is Well-Controlled by Long-Term Macrolide Therapy. 2016 Intern. Med. pmid:26831030
Deloose E et al. The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway. 2016 Am. J. Clin. Nutr. pmid:26817505
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Wu H et al. In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea. 2016 Appl. Microbiol. Biotechnol. pmid:26552796
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Ohbatake Y et al. Elevated alpha1-acid glycoprotein in gastric cancer patients inhibits the anticancer effects of paclitaxel, effects restored by co-administration of erythromycin. 2016 Clin. Exp. Med. pmid:26359244
Templeton I et al. A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4. 2016 Biopharm Drug Dispos pmid:26356245
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