erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Abdel Fattah NS and Darwish YW | Antibiogram testing of pediatric skin infections in the era of methicillin-resistant Staphylococci aureus: an Egyptian University Hospital-based study. | 2012 | Int. J. Dermatol. | pmid:22928620 |
| Kjeldgaard J et al. | Residual antibiotics disrupt meat fermentation and increase risk of infection. | 2012 | MBio | pmid:22930338 |
| Sakatis MZ et al. | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. | 2012 | Chem. Res. Toxicol. | pmid:22931300 |
| Li SL et al. | A single tube modified allele-specific-PCR for rapid detection of erythromycin-resistant Mycoplasma pneumoniae in Beijing. | 2012 | Chin. Med. J. | pmid:22931973 |
| Waśko A et al. | Genetic mechanisms of variation in erythromycin resistance in Lactobacillus rhamnosus strains. | 2012 | J. Antibiot. | pmid:22948255 |
| Leyden JJ | In vivo antibacterial effects of tretinoin-clindamycin and clindamycin alone on Propionibacterium acnes with varying clindamycin minimum inhibitory. | 2012 | J Drugs Dermatol | pmid:23377513 |
| Hess TM and Chew HF | Successful treatment of acute ocular involvement in Stevens-Johnson syndrome with amniotic membrane transplantation: a case report. | 2012 | Can. J. Ophthalmol. | pmid:23217513 |
| Fischer H et al. | In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. | 2012 | J. Med. Chem. | pmid:22122484 |
| Krasniqi S et al. | Blood, tissue, and intracellular concentrations of erythromycin and its metabolite anhydroerythromycin during and after therapy. | 2012 | Antimicrob. Agents Chemother. | pmid:22083477 |
| Nimgaonkar A et al. | Gastrointestinal dysmotility. | 2012 | Dig. Dis. Sci. | pmid:22038542 |
| Fazeli M et al. | Erythromycin enhances abomasal emptying in healthy unweaned lambs as shown by acetaminophen absorption test. | 2012 | J. Vet. Pharmacol. Ther. | pmid:22066489 |
| Kumar R et al. | Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22153939 |
| Reutenauer-Patte J et al. | Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. | 2012 | Am. J. Pathol. | pmid:22192627 |
| Villaseñor-Sierra A et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. | 2012 | Int. J. Infect. Dis. | pmid:22217469 |
| Luangtongkum T et al. | Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. | 2012 | Antimicrob. Agents Chemother. | pmid:22183170 |
| Soeters HM et al. | Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease. | 2012 | Antimicrob. Agents Chemother. | pmid:22232291 |
| Sunkara B et al. | Group B Streptococcus infections in non-pregnant adults: the role of immunosuppression. | 2012 | Int. J. Infect. Dis. | pmid:22236484 |
| Marlow N et al. | Characteristics of children with cerebral palsy in the ORACLE children study. | 2012 | Dev Med Child Neurol | pmid:22458348 |
| Romøren M et al. | Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway. | 2012 | Br J Clin Pharmacol | pmid:22463376 |
| Wormser GP et al. | Failure of topical antibiotics to prevent disseminated Borrelia burgdorferi infection following a tick bite in C3H/HeJ mice. | 2012 | J. Infect. Dis. | pmid:21930606 |
| Lee CH et al. | Case-crossover design: an alternative strategy for detecting drug-induced liver injury. | 2012 | J Clin Epidemiol | pmid:22445086 |
| Blode H et al. | Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. | 2012 | Contraception | pmid:22445438 |
| Kanazu T et al. | Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. | 2012 | Biopharm Drug Dispos | pmid:22447511 |
| Liu X et al. | Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment. | 2012 | Toxicol. Lett. | pmid:22450446 |
| Rahube TO and Yost CK | Characterization of a mobile and multiple resistance plasmid isolated from swine manure and its detection in soil after manure application. | 2012 | J. Appl. Microbiol. | pmid:22486928 |
| Campelo FA et al. | [Phenotypes and mechanisms of resistance to macrolides and lincosamides in Streptococcus agalactiae isolates with clinical significance in an eight-year period (2002-2010)]. | 2012 | Rev Esp Quimioter | pmid:22488541 |
| Sui Q et al. | Identification of priority pharmaceuticals in the water environment of China. | 2012 | Chemosphere | pmid:22591850 |
| Constable PD et al. | Evidence-based use of prokinetic drugs for abomasal disorders in cattle. | 2012 | Vet. Clin. North Am. Food Anim. Pract. | pmid:22374117 |
| Mehra T et al. | Treatment of severe acne with low-dose isotretinoin. | 2012 | Acta Derm. Venereol. | pmid:22377969 |
| Ogawa W et al. | Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. | 2012 | Gene | pmid:22391093 |
| Diacon AH et al. | Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22391540 |
| Peano C et al. | Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. | 2012 | Microb. Cell Fact. | pmid:22401291 |
| Chen CM | Erythromycin for the treatment of feeding intolerance in preterm infants. | 2012 | Pediatr Neonatol | pmid:22348487 |
| Ng YY et al. | Efficacy of intermediate-dose oral erythromycin on very low birth weight infants with feeding intolerance. | 2012 | Pediatr Neonatol | pmid:22348492 |
| Yoon SB et al. | The effect of exenatide and erythromycin on postprandial symptoms and their relation to gastric functions. | 2012 | Digestion | pmid:22354133 |
| Chhun S et al. | The cytochrome P-450 2C9/2C19 but not the ABCB1 genetic polymorphism may be associated with the liver cytochrome 3A4 induction by phenytoin. | 2012 | J Clin Psychopharmacol | pmid:22561479 |
| El-Adawy H et al. | Determination of antimicrobial sensitivities of Campylobacter jejuni isolated from commercial turkey farms in Germany. | 2012 | Avian Dis. | pmid:23397839 |
| He JL et al. | [Distribution of anaerobes in periodontal abscess and its resistance to antibiotics]. | 2012 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:23328096 |
| Smith EM et al. | In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes. | 2012 | Aquat. Toxicol. | pmid:22000335 |
| Mercer BM et al. | The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. | 2012 | Am. J. Obstet. Gynecol. | pmid:22000668 |
| Pendela M et al. | Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. | 2012 | Anal Bioanal Chem | pmid:22002558 |
| Parhi A et al. | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23058886 |
| Wilson BB et al. | An atypical presentation of erythrasma. | 2012 | J. Am. Acad. Dermatol. | pmid:23062922 |
| Zhou L et al. | Molecular characteristics of erythromycin-resistant Streptococcus pneumoniae from pediatric patients younger than five years in Beijing, 2010. | 2012 | BMC Microbiol. | pmid:23043378 |
| Cannon JA et al. | Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. | 2012 | Dis. Colon Rectum | pmid:23044677 |
| Kaul M et al. | A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. | 2012 | J. Med. Chem. | pmid:23050700 |
| Du Plessis LH et al. | In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum. | 2012 | J. Antibiot. | pmid:23093037 |
| Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible resistance to erythromycin in Streptococcus pyogenes. | 2012 | Antimicrob. Agents Chemother. | pmid:23027190 |
| Marks LR et al. | The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents. | 2012 | PLoS ONE | pmid:22905269 |
| Weisman LE et al. | Appropriate antibiotic therapy improves Ureaplasma sepsis outcome in the neonatal mouse. | 2012 | Pediatr. Res. | pmid:22907617 |