erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kelly C et al. | Macrolide antibiotics for bronchiectasis. | 2018 | Cochrane Database Syst Rev | pmid:29543980 |
Liu J et al. | Investigation of pharmaceutically active compounds in an urban receiving water: Occurrence, fate and environmental risk assessment. | 2018 | Ecotoxicol. Environ. Saf. | pmid:29476970 |
Chen YB et al. | Molecular epidemiology and antimicrobial susceptibility of Clostridium difficile isolated from hospitals during a 4-year period in China. | 2018 | J. Med. Microbiol. | pmid:29160203 |
Brown RG et al. | Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin. | 2018 | BMC Med | pmid:29361936 |
Pawlowski AC et al. | The evolution of substrate discrimination in macrolide antibiotic resistance enzymes. | 2018 | Nat Commun | pmid:29317655 |
Sendra M et al. | Erythromycin sensitivity across different taxa of marine phytoplankton. A novel approach to sensitivity of microalgae and the evolutionary history of the 23S gene. | 2018 | Aquat. Toxicol. | pmid:30290295 |
Xiaolong X et al. | Combination of oral nonabsorbable and intravenous antibiotics versus intravenous antibiotics alone in the prevention of surgical site infections after elective colorectal surgery in pediatric patients: A retrospective study. | 2018 | Medicine (Baltimore) | pmid:30200175 |
Aderemi AO et al. | Oxidative stress responses and cellular energy allocation changes in microalgae following exposure to widely used human antibiotics. | 2018 | Aquat. Toxicol. | pmid:30125766 |
Ababou A | New insights into the structural and functional involvement of the gate loop in AcrB export activity. | 2018 | Biochim. Biophys. Acta | pmid:29126836 |
Voigt M et al. | Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation. | 2018 | J Vis Exp | pmid:30124654 |
Li A et al. | Development of Guanfacine Extended-Release Dosing Strategies in Children and Adolescents with ADHD Using a Physiologically Based Pharmacokinetic Model to Predict Drug-Drug Interactions with Moderate CYP3A4 Inhibitors or Inducers. | 2018 | Paediatr Drugs | pmid:29098603 |
Zhang M et al. | Co-selection of antibiotic resistance via copper shock loading on bacteria from a drinking water bio-filter. | 2018 | Environ. Pollut. | pmid:29059628 |
Scarano C et al. | Antibiotic resistance of Aeromonas ssp. strains isolated from Sparus aurata reared in Italian mariculture farms. | 2018 | Int. J. Food Microbiol. | pmid:30081345 |
Marchant JM et al. | Antibiotics for prolonged wet cough in children. | 2018 | Cochrane Database Syst Rev | pmid:30062732 |
Karine de Sousa A et al. | New roles of fluoxetine in pharmacology: Antibacterial effect and modulation of antibiotic activity. | 2018 | Microb. Pathog. | pmid:30056107 |
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Young N et al. | Integrated point-of-care testing (POCT) of HIV, syphilis, malaria and anaemia in antenatal clinics in western Kenya: A longitudinal implementation study. | 2018 | PLoS ONE | pmid:30028852 |
Dos Santos JFS et al. | In vitro e in silico evaluation of the inhibition of Staphylococcus aureus efflux pumps by caffeic and gallic acid. | 2018 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:30017074 |
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Mishra RK et al. | Diffuse panbronchiolitis research in MEDLINE (1969-2017): Report of a bibliometric analysis. | 2018 | Respir Investig | pmid:30008294 |
Zikic A et al. | Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis. | 2018 | J Pediatric Infect Dis Soc | pmid:30007329 |
Cheng L et al. | Bioaccumulation, tissue distribution and joint toxicity of erythromycin and cadmium in Chinese mitten crab (Eriocheir sinensis). | 2018 | Chemosphere | pmid:30005348 |
Sendra M et al. | Effect of erythromycin and modulating effect of CeO NPs on the toxicity exerted by the antibiotic on the microalgae Chlamydomonas reinhardtii and Phaeodactylum tricornutum. | 2018 | Environ. Pollut. | pmid:29990943 |
Guo Y et al. | The draft genomes and investigation of serotype distribution, antimicrobial resistance of group B Streptococcus strains isolated from urine in Suzhou, China. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29945615 |
Choi KR et al. | Metabolomics for industrial fermentation. | 2018 | Bioprocess Biosyst Eng | pmid:29931578 |
Tapia C et al. | 2018 | Rev Chilena Infectol | pmid:29912257 | |
Jaén-Gil A et al. | An automated on-line turbulent flow liquid-chromatography technology coupled to a high resolution mass spectrometer LTQ-Orbitrap for suspect screening of antibiotic transformation products during microalgae wastewater treatment. | 2018 | J Chromatogr A | pmid:29910089 |
Kulesa A et al. | Combinatorial drug discovery in nanoliter droplets. | 2018 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29899149 |
Ersoy B et al. | The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs. | 2018 | J Laryngol Otol | pmid:29888693 |
Nishina T et al. | [A case of relapsed neurosyphilis with progressive left hemiparesis]. | 2018 | Rinsho Shinkeigaku | pmid:29863099 |
Zhang Z et al. | The pathogenic and antimicrobial characteristics of an emerging Streptococcus agalactiae serotype IX in Tilapia. | 2018 | Microb. Pathog. | pmid:29859291 |
Zhou P et al. | Cellular metabolism network of Bacillus thuringiensis related to erythromycin stress and degradation. | 2018 | Ecotoxicol. Environ. Saf. | pmid:29857237 |
Azrad M et al. | Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli: comparison between Etest and a broth dilution method. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29792197 |
Williams PCM and Berkley JA | Guidelines for the management of paediatric cholera infection: a systematic review of the evidence. | 2018 | Paediatr Int Child Health | pmid:29790841 |
Bhardwaj N et al. | Antimicrobial resistance in beta-haemolytic streptococci in India: A four-year study. | 2018 | Indian J. Med. Res. | pmid:29749365 |
Ma L et al. | Biochemical characterization of a recombinant Lactobacillus acidophilus strain expressing exogenous FomA protein. | 2018 | Arch. Oral Biol. | pmid:29747062 |
Sebrechts T et al. | Serial Gastric Ultrasound to Evaluate Gastric Emptying After Prokinetic Therapy With Domperidone and Erythromycin in a Surgical Patient With a Full Stomach: A Case Report. | 2018 | A A Pract | pmid:29634526 |
Sorlózano-Puerto A et al. | Susceptibility of clinical isolates of Campylobacter jejuni and Campylobacter coli to colistin. | 2018 | New Microbiol. | pmid:29620788 |
Subirats J et al. | Emerging contaminants and nutrients synergistically affect the spread of class 1 integron-integrase (intI1) and sul1 genes within stable streambed bacterial communities. | 2018 | Water Res. | pmid:29573631 |
Wang XF et al. | Protective Effect of Quercetin in LPS-Induced Murine Acute Lung Injury Mediated by cAMP-Epac Pathway. | 2018 | Inflammation | pmid:29569077 |
Robichaux WG and Cheng X | Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development. | 2018 | Physiol. Rev. | pmid:29537337 |
Carfora V et al. | Non-toxigenic Corynebacterium ulcerans sequence types 325 and 339 isolated from two dogs with ulcerative lesions in Italy. | 2018 | J. Vet. Diagn. Invest. | pmid:29528813 |
de Jong A et al. | Antimicrobial susceptibility of enterococci recovered from healthy cattle, pigs and chickens in nine EU countries (EASSA Study) to critically important antibiotics. | 2018 | Vet. Microbiol. | pmid:29519512 |
Vignaroli C et al. | Antibiotic and heavy metal resistance in enterococci from coastal marine sediment. | 2018 | Environ. Pollut. | pmid:29502003 |
Papagiannitsis CC et al. | First Description in Greece of mphC-Positive Staphylococci Causing Subclinical Mastitis in Ewes. | 2018 | Microb. Drug Resist. | pmid:29489448 |
Peng J et al. | Blue-light photoelectrochemical sensor based on nickel tetra-amined phthalocyanine-graphene oxide covalent compound for ultrasensitive detection of erythromycin. | 2018 | Biosens Bioelectron | pmid:29428591 |
Akoachere JTK et al. | Bacterial and parasitic contaminants of salad vegetables sold in markets in Fako Division, Cameroon and evaluation of hygiene and handling practices of vendors. | 2018 | BMC Res Notes | pmid:29409524 |
Tatsuno I et al. | Functional Predominance of msr(D), Which Is More Effective as mef(A)-Associated Than mef(E)-Associated, Over mef(A)/mef(E) in Macrolide Resistance in Streptococcus pyogenes. | 2018 | Microb. Drug Resist. | pmid:29406792 |
Kim S et al. | Molecular Epidemiological Features and Antibiotic Susceptibility Patterns of Streptococcus dysgalactiae subsp. equisimilis Isolates from Korea and Japan. | 2018 | Ann Lab Med | pmid:29401555 |
Shi X et al. | [The research of the innate defense regulator peptide on the effects of methicillin resistant staphylococcus aureus biofilm]. | 2018 | Zhonghua Yi Xue Za Zhi | pmid:29397617 |
Zhao D et al. | The motilin agonist erythromycin increases hunger by modulating homeostatic and hedonic brain circuits in healthy women: a randomized, placebo-controlled study. | 2018 | Sci Rep | pmid:29379095 |
Hosono Y et al. | The association between erythromycin monotherapy for Mycobacterium avium complex lung disease and cross-resistance to clarithromycin: A retrospective case-series study. | 2018 | J. Infect. Chemother. | pmid:29361415 |
Chuo SC et al. | Reverse micelle Extraction of Antibiotics using an Eco-friendly Sophorolipids Biosurfactant. | 2018 | Sci Rep | pmid:29323139 |
Teixeira DDS et al. | Topical chlorhexidine, povidone-iodine and erythromycin in the repair of traumatic ulcers on the rat tongue: Clinical, histological and microbiological evaluation. | 2018 | Arch. Oral Biol. | pmid:29316457 |
Patil BN and Taranath TC | Limonia acidissima L. leaf mediated synthesis of silver and zinc oxide nanoparticles and their antibacterial activities. | 2018 | Microb. Pathog. | pmid:29248515 |
Ramos CJ et al. | The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability. | 2018 | J. Biol. Chem. | pmid:29158262 |
Dias-Souza MV et al. | Euterpe oleracea pulp extract: Chemical analyses, antibiofilm activity against Staphylococcus aureus, cytotoxicity and interference on the activity of antimicrobial drugs. | 2018 | Microb. Pathog. | pmid:29146496 |
Mendel M et al. | Interactions between erythromycin, flunixin meglumine, levamisole and plant secondary metabolites towards bovine gastrointestinal motility-in vitro study. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28913883 |
Cao Q et al. | Haemophilus parasuis CpxRA two-component system confers bacterial tolerance to environmental stresses and macrolide resistance. | 2018 | Microbiol. Res. | pmid:29146255 |
Kasey CM et al. | Development of Transcription Factor-Based Designer Macrolide Biosensors for Metabolic Engineering and Synthetic Biology. | 2018 | ACS Synth Biol | pmid:28950701 |
Jammal J et al. | Eliciting improved antibacterial efficacy of host proteins in the presence of antibiotics. | 2018 | FASEB J. | pmid:28904017 |
Campagnolo ER et al. | Pet-associated Campylobacteriosis: A persisting public health concern. | 2018 | Zoonoses Public Health | pmid:28834267 |
Pourakbari B et al. | Antimicrobial Resistance Patterns of the Gram-positive Bacteria Isolated from Children with Bloodstream Infection in an Iranian Referral Hospital: A 6-year Study. | 2018 | Infect Disord Drug Targets | pmid:28828970 |
Hui-Min Y et al. | Analysis of distribution and antibiotic resistance of pathogens isolated from the paediatric population in Shenmu Hospital from 2011-2015. | 2018 | J. Int. Med. Res. | pmid:28789605 |
Escudero AI et al. | Pharmacokinetics of deflazacort in rabbits after intravenous and oral administration and its interaction with erythromycin. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28741668 |
Schafhauser BH et al. | Global review and analysis of erythromycin in the environment: Occurrence, bioaccumulation and antibiotic resistance hazards. | 2018 | Environ. Pollut. | pmid:29587215 |
Kleinert C et al. | T lymphocyte-proliferative responses of harbor seal (Phoca vitulina) peripheral blood mononuclear cells (PBMCs) exposed to pharmaceuticals in vitro. | 2018 | Mar. Pollut. Bull. | pmid:29475659 |
Chen CJ et al. | Clinical and molecular features of MDR livestock-associated MRSA ST9 with staphylococcal cassette chromosome mecXII in humans. | 2018 | J. Antimicrob. Chemother. | pmid:29048488 |
Chen C et al. | Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. | 2017 | Bioprocess Biosyst Eng | pmid:27709326 |
Gonser LI et al. | Systemic therapy of ocular and cutaneous rosacea in children. | 2017 | J Eur Acad Dermatol Venereol | pmid:28621909 |
Sato T et al. | Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. | 2017 | Microbiol. Immunol. | pmid:28504455 |
Wozniak A et al. | Importance of adhesins in the recurrence of pharyngeal infections caused by Streptococcus pyogenes. | 2017 | J. Med. Microbiol. | pmid:28463664 |
Pavlova A et al. | Toward the rational design of macrolide antibiotics to combat resistance. | 2017 | Chem Biol Drug Des | pmid:28419786 |
Szczepanska B et al. | Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. | 2017 | BMC Microbiol. | pmid:28376713 |
Mingmongkolchai S and Panbangred W | In vitro evaluation of candidate Bacillus spp. for animal feed. | 2017 | J. Gen. Appl. Microbiol. | pmid:28331163 |
Attaran B et al. | Effect of biofilm formation by clinical isolates of on the efflux-mediated resistance to commonly used antibiotics. | 2017 | World J. Gastroenterol. | pmid:28275296 |
Nowakiewicz A et al. | Determination of antimicrobial resistance of Enterococcus strains isolated from pigs and their genotypic characterization by method of amplification of DNA fragments surrounding rare restriction sites (ADSRRS fingerprinting). | 2017 | J. Med. Microbiol. | pmid:28260584 |
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Owen L et al. | A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. | 2017 | Phytother Res | pmid:28124400 |
Chen K et al. | Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China. | 2017 | BMC Infect. Dis. | pmid:28122513 |
Berni E et al. | Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. | 2017 | BMJ Open | pmid:28115334 |
Wei L et al. | Transformation of erythromycin during secondary effluent soil aquifer recharging: Removal contribution and degradation path. | 2017 | J Environ Sci (China) | pmid:28115128 |
Koryakina I et al. | Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. | 2017 | ACS Chem. Biol. | pmid:28103677 |
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Austin BA and Fleischer AB | The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin. | 2017 | J Dermatolog Treat | pmid:27425633 |
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Yi M et al. | Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis. | 2017 | Arch. Biochem. Biophys. | pmid:28347661 |
Duelge KJ et al. | An LC-MS/MS method for the determination of antibiotic residues in distillers grains. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28415016 |
Svetlov MS et al. | Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29229833 |
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