erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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DITTLER EL | Upper abdominal pain and intrahepatic cholestasis as manifestations of sensitivity to ilosone. | 1962 | Am. J. Gastroenterol. | pmid:14028076 |
VIRANUVATTI V and BISESHURARIT P | Clinical trial of erythromycin in amebic liver abscess. | 1955 | Am. J. Gastroenterol. | pmid:13228406 |
Jones KL et al. | The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. | 1999 | Am. J. Gastroenterol. | pmid:10445530 |
Weber FH et al. | Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. | 1993 | Am. J. Gastroenterol. | pmid:8470625 |
Ruffin WK | Erythromycin: a postoperative jumpstart? | 1994 | Am. J. Gastroenterol. | pmid:7909647 |
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McNulty CA | The treatment of Campylobacter-associated gastritis. | 1987 | Am. J. Gastroenterol. | pmid:3493685 |
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MartÃnez-Maldonado M | Postinfectious glomerulonephritis. | 2000 | Am. J. Kidney Dis. | pmid:10636819 |
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Silang R et al. | Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying. | 2001 | Am. J. Kidney Dis. | pmid:11157368 |
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Gumaste VV | Erythromycin-induced pancreatitis. | 1989 | Am. J. Med. | pmid:2729328 |
Curtis LH et al. | Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. | 2003 | Am. J. Med. | pmid:12586234 |
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Klein JO | Emerging perspectives in management and prevention of infections of the respiratory tract in infants and children. | 1985 | Am. J. Med. | pmid:4014286 |
Sacristán JA and Soto J | Erythromycin ototoxicity: methodology and conclusions. | 1993 | Am. J. Med. | pmid:8430720 |
Wong KF et al. | Psittacosis-associated hemophagocytic syndrome. | 1991 | Am. J. Med. | pmid:1867249 |
Tablan OC and Reyes MP | Chronic interstitial pulmonary fibrosis following Mycoplasma pneumoniae pneumonia. | 1985 | Am. J. Med. | pmid:4025379 |
Vianna NJ and Hinman AR | Rocky Mountain spotted fever on Long Island. Epidemiologic and clinical aspects. | 1971 | Am. J. Med. | pmid:5129543 |
DAVIS DS and ROMANSKY MJ | Successful treatment of gonococcic endocarditis with erythromycin; review of the literature. | 1956 | Am. J. Med. | pmid:13354638 |
Augenbraun MH et al. | Chlamydia pneumoniae pneumonia with pleural effusion: diagnosis by culture. | 1991 | Am. J. Med. | pmid:1951390 |
Massarotti EM et al. | Treatment of early Lyme disease. | 1992 | Am. J. Med. | pmid:1313637 |
Swanson DJ et al. | Erythromycin ototoxicity: prospective assessment with serum concentrations and audiograms in a study of patients with pneumonia. | 1992 | Am. J. Med. | pmid:1731511 |
Petersdorf RG | Antimicrobial prophylaxis of bacterial endocarditis. Prudent caution or bacterial overkill? | 1978 | Am. J. Med. | pmid:99033 |
Moellering RC et al. | Endocarditis due to group D streptococci. Comparison of disease caused by streptococcus bovis with that produced by the enterococci. | 1974 | Am. J. Med. | pmid:4843895 |
Bent S et al. | Antibiotics in acute bronchitis: a meta-analysis. | 1999 | Am. J. Med. | pmid:10403354 |
Friedland L et al. | Ocular and pericardial involvement in Legionnaires' disease. | 1984 | Am. J. Med. | pmid:6507461 |
Nichols RL | Use of prophylactic antibiotics in surgical practice. | 1981 | Am. J. Med. | pmid:7011021 |
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Stocks JM et al. | Ofloxacin in community-acquired lower respiratory infections. A comparison with amoxicillin or erythromycin. | 1989 | Am. J. Med. | pmid:2690620 |
Dull JS et al. | Successful treatment of gastroparesis with erythromycin in a patient with progressive systemic sclerosis. | 1990 | Am. J. Med. | pmid:2220887 |
Watanakunakorn C | Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. | 1976 | Am. J. Med. | pmid:1045861 |
Bowler WA et al. | Gastrointestinal side effects of intravenous erythromycin: incidence and reduction with prolonged infusion time and glycopyrrolate pretreatment. | 1992 | Am. J. Med. | pmid:1546723 |
Bor DH and Himmelstein DU | Endocarditis prophylaxis for patients with mitral valve prolapse. A quantitative analysis. | 1984 | Am. J. Med. | pmid:6711576 |
Unertl KE et al. | Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. | 1989 | Am. J. Med. | pmid:2589356 |
Trimble GX | Acute pancreatitis induced by erythromycin. | 1989 | Am. J. Med. | pmid:2589410 |