erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Biberfeld G and Sterner G | A study of Mycoplasma pneumoniae infections in families. | 1969 | Scand. J. Infect. Dis. | pmid:4938476 |
Sprunt K et al. | Oral antibiotics in patients with heart disease: case report of child facing oropharyngeal surgery with oropharyngeal viridans streptococci resistant to penicillin and, following oral erythromycin therapy, to penicillin, erythromycin, and lincomycin. | 1969 | Pediatrics | pmid:5191724 |
Clark H | An evaluation of antibiotic prophylaxis in cardiac catheterization. | 1969 | Am. Heart J. | pmid:5192402 |
Guggenheim B et al. | [Modifications of the oral bacterial flora and their influence on dental caries in the rat. 3. The cariogenicity of an erythromycin-resistant strain of Streptococcus mutans compared to its non-resistant parent strain]. | 1969 | Helv Odontol Acta | pmid:5192679 |
Voropaeva SD | [Multiple resistance of staphylococci, isolated from the patients]. | 1969 | Antibiotiki | pmid:5192737 |
Jessen O et al. | Changing staphylococci and staphylococcal infections. A ten-year study of bacteria and cases of bacteremia. | 1969 | N. Engl. J. Med. | pmid:5194719 |
Bals MG and FilipescÅ S | The antistaphylococcal activity of Rifampicin. | 1969 | Arzneimittelforschung | pmid:5194845 |
Tardrew PL et al. | Antibacterial activity of 2'-esters of erythromycin. | 1969 | Appl Microbiol | pmid:5807154 |
Bezborodov AM et al. | [Coenzyme A content of the mycelium of antibiotic-producing Actinomycetes]. | 1969 | Antibiotiki | pmid:5808677 |
Rozenfel'd GS et al. | [Study of composition of preparations of erythromycin-base]. | 1969 | Antibiotiki | pmid:5361827 |
Bourse R et al. | [The effect of erythromycin plus lincomycin association on renal staphylococcia in mice induced by "dissociated resistant" Staphylococcus aureus]. | 1969 | Ann Inst Pasteur (Paris) | pmid:5363514 |
Lie JT et al. | Effect of antimicrobial agents on the Euglena method of serum vitamin B12 assay. | 1969 | J. Clin. Pathol. | pmid:5364439 |
Nakahara T et al. | [Effect of drug administration on the child with progressive muscular dystrophy]. | 1969 | Iryo | pmid:5364983 |
Bebe M | [Therapeutic indications in staphylococcal pleursy and pneumonia. 114 cases]. | 1969 | Ann Pediatr (Paris) | pmid:5365506 |
Iwamoto HK and Brennan WR | The effect of demeclocycline, methacycline, and erythromycin on tooth color in the rat. | 1969 | Toxicol. Appl. Pharmacol. | pmid:4975609 |
Wiersum J et al. | A comparison of erythromycin and methacycline in the treatment of common bacterial infections. | 1969 | Curr Ther Res Clin Exp | pmid:4976333 |
Lagert IK et al. | [Antibiotic treatment in acute renal insufficiency in obstetrics and gynecology]. | 1969 | Klin Med (Mosk) | pmid:5406822 |
Baer PN et al. | Studies on experimental calculus fomration in the rat XIII. Effect of strain, antibiotics and foster feeding. | 1969 | J. Periodontol. | pmid:5251209 |
Waksman SA | Successes and failures in the search for antibiotics. | 1969 | Adv. Appl. Microbiol. | pmid:4195044 |
Descrozailles C et al. | [A case of facial-ophthalmic thrombophlebitis during dental treatment]. | 1969 | Rev Stomatol Chir Maxillofac | pmid:5254109 |
Lobene RR et al. | Effect of erythromycin on dental plaque and plaque forming microorganisms of man. | 1969 | J. Periodontol. | pmid:5255346 |
Delaire J | [Use of erythromycin ethyl succinate tablets for chewing, their value in dentistry]. | 1969 | Chir Dent Fr | pmid:4981637 |
Myall RW and Gregory HS | Current trends in the prevention of bacterial endocarditis in susceptible patients receiving dental care. | 1969 | Oral Surg. Oral Med. Oral Pathol. | pmid:4982061 |
Muschel LH et al. | Sensitivity of Pseudomonas aeruginosa to normal serum and to polymyxin. | 1969 | J. Bacteriol. | pmid:4306538 |
Elston HR et al. | Listeria monocytogenes endocarditis: a clinical and bacteriological report. | 1969 | Arch. Intern. Med. | pmid:4982382 |
Stone NH et al. | Empirical selection of antibiotics for hand infections. | 1969 | J Bone Joint Surg Am | pmid:4307419 |
Tereshin IM | [Mechanism of action of mitomycin C on genetic transformation of hemolytic Streptococci]. | 1969 | Antibiotiki | pmid:4982962 |
Serebrennikova II | [Correlation between sensitivity of diphtheria bacteria to antibiotics and the presence of fungi of the Candida order]. | 1969 | Antibiotiki | pmid:4982964 |
Veselov AIa | [Dynamics of sensitivity to antibiotics of pathogenic staphylococci, isolated from different sources]. | 1969 | Antibiotiki | pmid:4889838 |
Kalabukhova NF and Ermol'eva ZV | [Comparative study of sensitivity of enteropathogenic coli bacteria and proteus to ampicillin and its combination with other antibiotics]. | 1969 | Antibiotiki | pmid:4889844 |
Ekisenina NI et al. | [Use of prodigiozan in chronic diseases of intestine]. | 1969 | Antibiotiki | pmid:4889845 |
Cerná J et al. | The effect of antibiotics on the coded binding of peptidyl-tRNA to the ribosome and on the transfer of the peptidyl residue to puromycin. | 1969 | Eur. J. Biochem. | pmid:4891613 |
Grekova GN | [Sensitivity of Proteus vulgaris, isolated from patients with acute disorders of gastro-intestinal tract, to different antibiotics and furacillin]. | 1969 | Antibiotiki | pmid:4891714 |
Weisblum B and Demohn V | Erythromycin-inducible resistance in Staphylococcus aureus: survey of antibiotic classes involved. | 1969 | J. Bacteriol. | pmid:5784204 |
Raveau MJ | [Use in pediatrics of a new form of erythromycin: erythromycin ethyl succinate]. | 1969 | J Med Lyon | pmid:5784250 |
DeSalva SJ et al. | Lethal effects of antibiotics in hamsters. | 1969 | Toxicol. Appl. Pharmacol. | pmid:5787519 |
Lapinski EM and Flakas ED | Effects of antibiotics on induction, viability, and reversion potential of L-forms of Haemophilus influenzae. | 1969 | J. Bacteriol. | pmid:5305776 |
Osono T et al. | [Studies on josamycin. 3. (1) Bacteriological studies. (2) Protective effect against infections due to pathogenic bacteria. (3) Absorption, excretion, distribution in organs and in vivo activities]. | 1969 | Jpn J Antibiot | pmid:4389777 |
Ravin AW et al. | Genetic and biochemical studies of suppression of ribosomal resistance to streptomycin and erythromycin in Pneumococcus. | 1969 | Genetics | pmid:4389851 |
dos Santos Morais ML | [Clinico-pathological results using erythromycin stearate in the treatment of intestinal amebiasis]. | 1969 | Hospital (Rio J) | pmid:5306428 |
Waitz JA et al. | Biological activity of megalomicin, a new Micromonospora-produced macrolide antibiotic complex. | 1969 | J. Antibiot. | pmid:4390258 |
de Santana AF | [Ethyl succinate erythromycin and trisulphapyridine combination in the treatment of respiratory infections in pediatric outpatients]. | 1969 | Hospital (Rio J) | pmid:5306432 |
Gabor M and Hotchkiss RD | Differences in rate of phenotypic expression in separated strands of pneumococcal transforming DNA and evidence for change of reading direction. | 1969 | Genetics | pmid:4390535 |
Bestani WJ | [An erythromycin-trisulfapyrimidine combination in genitourinary infections]. | 1969 | Hospital (Rio J) | pmid:5306490 |
Morbidelli R et al. | [Evolution of antibiotic sensitivity of 336 staphylococcal strains from 1956-1967]. | 1968 Nov-Dec | G Batteriol Virol Immunol | pmid:4907246 |
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Fleurette J | [The sensitivity of pathogenic staphylococci of human origin to two recent antibiotics: cephalotin and lincomycin]. | 1968 May-Jun | Ann. Biol. Clin. (Paris) | pmid:5681856 |
Mielech R et al. | [Studies on the effect of most frequently used antibiotics on the course of syphilitic infection]. | 1968 Mar-Apr | Przegl Dermatol | pmid:4877997 |
Freidel C and Deidier C | [The role of Abboticine in stomatologic hospital practice. (Study and report on 26 cases)]. | 1968 Jul-Aug | Ann Odontostomatol (Lyon) | pmid:5683852 |
Meeroff M | [Treatment of intestinal amebiasis with erythromycin stearate. Parastitic study of fecal material]. | 1968 Jan-Jun | Bol Chil Parasitol | pmid:5705124 |
Jakubowski A et al. | [Experimental studies in vivo on the effect upon Trepomena pallidum of some antibiotics other than penicillin]. | 1968 Jan-Feb | Przegl Dermatol | pmid:4867335 |
Schirger A et al. | Erythromycin for prophylaxis prior to oral surgery in patients allergic to panicillin. | 1968 Jan-Feb | Northwest Dent | pmid:5240271 |
Avian tuberculosis. | 1968 | Scott Med J | pmid:4884700 | |
Anaka K and Teraoka H | Effect of erythromycin on polylysine synthesis directed by polyadenylic acid in an Escherichia coli cell-free system. | 1968 | J. Biochem. | pmid:4885037 |
Bouanchaud DH et al. | Elimination by ethidium bromide of antibiotic resistance in enterobacteria and staphylococci. | 1968 | J. Gen. Microbiol. | pmid:4885039 |
Tanaka K et al. | Erythromycin-resistant mutant of Escherichia coli with altered ribosomal protein component. | 1968 | Science | pmid:4886608 |
Woods R | Antibiotic treatment of pyogenic infections of dental origin. | 1968 | Aust Dent J | pmid:5240656 |
Berthelot et al. | [Clinical study and determination of blood and salivary level of erythromycin ethyl-succinate]. | 1968 | Inf Dent | pmid:5245648 |
Cooper RG et al. | An erythromycin-resistant pneumococcus. | 1968 | Med. J. Aust. | pmid:4385911 |
Lang N et al. | On the mechanism of hormone action. VII. Induction by cortisol of a messenger RNA coding for tyrosine-alpha-ketoglutarate transaminase for an in vitro system. | 1968 | Acta Endocrinol. | pmid:4384442 |
Petricević I et al. | [Hepatitis caused by erythromycin]. | 1968 | Lijec Vjesn | pmid:5195777 |
Schonell ME et al. | Disseminated infection with Mycobacterium avium: I. Clinical features, treatment and pathology. | 1968 | Tubercle | pmid:4969143 |
Clark J et al. | Disseminated infection with Mycobacterium avium: II. Bacteriology and drug susceptibility. | 1968 | Tubercle | pmid:4969144 |
Saggers BA and Lawson D | In vivo penetration of antibiotics into sputum in cystic fibrosis. | 1968 | Arch. Dis. Child. | pmid:4969417 |
Franco S et al. | Erythromycin in childhood pneumonias. | 1968 | Curr Ther Res Clin Exp | pmid:4969674 |
Willcox RR | Erythromycin in the treatment of non-gonococcal urethritis. | 1968 | Br J Vener Dis | pmid:5761021 |
Schultz EJ | Evaluation of erythromycin in the treatment of infectious bovine mastitis. | 1968 | J. Am. Vet. Med. Assoc. | pmid:5761379 |
Gabraschanski P | [Gallimycin for therapy and prophylaxis of some diseases or the rock partridge in Bulgaria]. | 1968 | Dtsch Tierarztl Wochenschr | pmid:5693286 |
Fekety FR | Gastrointestinal complications of antibiotic therapy. | 1968 | JAMA | pmid:5694045 |
Benzi G et al. | [Effect of erythromycin, various tetracyclines and rifomycin SV, on extrahepatic bile ducts]. | 1968 | Boll Chim Farm | pmid:4976427 |
Wakuta T | Mutual relationship of Candida and Lactobacillus in mixed culture. | 1968 | Bull. Tokyo Med. Dent. Univ. | pmid:4976549 |
Vakulenko NA | [Unification of the method for determination of biological activity of antibiotics by means of single test culture]. | 1968 | Antibiotiki | pmid:4976625 |
Velluti G and Grifa P | [In vitro activity of erythromycin on various mycobacterium strains]. | 1968 | G Mal Infett Parassit | pmid:4976935 |
Sugiyama H | [Experimental studies on control of dental caries. 2. Erythromycin and oral microbial flora]. | 1968 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5261349 |
Puito L | [Antibiotic therapy in infancy]. | 1968 | Pediatria (Napoli) | pmid:4312284 |
Sprunt K et al. | Penicillin resistant alpha Streptococci in pharynx of patients given oral penicillin. | 1968 | Pediatrics | pmid:5188913 |
Novick RP and Roth C | Plasmid-linked resistance to inorganic salts in Staphylococcus aureus. | 1968 | J. Bacteriol. | pmid:5646621 |
Alberti RL | Teeth discoloration and enamel hypoplasia caused by erythromycin. | 1968 | S. Afr. Med. J. | pmid:5647172 |
Doyle WM et al. | Pulmonary disease caused by Mycobacterium xenopei. | 1968 | Am. Rev. Respir. Dis. | pmid:5647216 |
Thomas DY and Wilkie D | Inhibition of mitochondrial synthesis in yeast by erythromycin: cytoplasmic and nuclear factors controlling resistance. | 1968 | Genet. Res. | pmid:5648765 |
Osman HG et al. | Factors influencing the biosynthesis of erythromycin by Streptomyces erythreus. | 1968 | Z. Allg. Mikrobiol. | pmid:4916831 |
Macfarlane JA et al. | Spiramycin the the prevention of postoperative staphylococcal infection. | 1968 | Lancet | pmid:4169066 |
Pacha RE | Characteristics of Cytophaga psychrophila (Borg) isolated during outbreaks of bacterial cold-water disease. | 1968 | Appl Microbiol | pmid:4169926 |
Chisholm WS | Erythromycin-sulfas in pediatric practice: efficacy and patient acceptance. | 1968 | Ariz Med | pmid:5674274 |
Johnstone FR and Cockcroft WH | Clostridium welchii resistance to tetracycline. | 1968 | Lancet | pmid:4170649 |
Higashide E et al. | Enduracidin, a new antibiotic. I. Streptomyces fungicidicus No. B5477, an enduracidin producing organism. | 1968 | J. Antibiot. | pmid:5674368 |
Hadida E et al. | [Dissecting cellulitis of the scalp]. | 1968 | Bull Soc Fr Dermatol Syphiligr | pmid:5677894 |
Chernomordik AB | [Antibiotic lincomycin]. | 1968 | Antibiotiki | pmid:4894135 |
VaÄsberg GE and Meshkov MI | [Treatment of patients with microbial eczema by prodigiozan in combination with antibiotics]. | 1968 | Antibiotiki | pmid:5678111 |
Gause GG and Grünberger D | Translational characteristics of ribosomes and coding properties of transfer RNA in the mutant of bacterium paracoli with the increased GC content of DNA. | 1968 | Biochim. Biophys. Acta | pmid:5680608 |
Wayland LG and Weiss PJ | Identification of antibiotics in sensitivity disks. | 1968 | J Pharm Sci | pmid:4173079 |
Swart H | [A case of Gaffkya sepsis]. | 1968 | Ned Tijdschr Geneeskd | pmid:5680825 |
Nakazawa S et al. | [Experimental chemotherapy of Proteus vulgaris infection]. | 1968 | Jpn J Antibiot | pmid:4299624 |
Hirasawa K | [Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders]. | 1968 | Jpn. Circ. J. | pmid:4299837 |
Alterio DL | [Clinico-parasitological evaluation of an anti-ameba therapeutic activity of a new non-absorbable erythromycin stearate preparation]. | 1968 | Hospital (Rio J) | pmid:5307504 |
Ganança MM | [Use of erythromycin suppositories in the treatment of otorhinolaryngologic infections in children]. | 1968 | Hospital (Rio J) | pmid:5307873 |
Barnes RW et al. | Studies of sterility of calf venous blood. | 1968 | Surgery | pmid:4300855 |
Ruczaj Z | Sensitivity of microorganisms to antibiotics produced by them. | 1968 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:4302938 |
Siegenthaler W et al. | [New antibiotics, with the exception of penicillins, streptomycin, tetracyclines and chloramphenicol]. | 1968 | Antibiot Chemother | pmid:4302993 |
Minkova GL | [On the sensitivity of microflora of burn wounds to antibiotics]. | 1968 | Antibiotiki | pmid:4305269 |