erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Lange A and Volkening R | [Resistance quota of some bacterial species to various antibiotics]. | 1968 | Med Welt | pmid:4888218 |
Shipley A et al. | T-strain mycoplasmas in non-specific urethritis. | 1968 | Med. J. Aust. | pmid:4872365 |
MosiÄchuk NM | [Permeability of the hemato-encephalic barrier to antibiotics in patients with infectious meningitis]. | 1968 | Zh Nevropatol Psikhiatr Im S S Korsakova | pmid:4872691 |
Aoki Y | Colicin type, biochemical type and drug-resistance pattern of Shigella sonnei isolated in Japan and its neighboring countries. | 1968 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:4874474 |
Garanin BA | [Analysis of the sensitivity toward some antibiotics of Salmonellas isolated from patients during 1960-1966]. | 1968 | Antibiotiki | pmid:4876633 |
Garanin BA | [Sensitivity toward antibiotics of Shigella Sonnei of individual fermentative types based on data from a hospital for communicable diseases during 1966]. | 1968 | Antibiotiki | pmid:4877060 |
Calabrò R et al. | [In vitro antibacteric activity of a combination of erythromycin, sulfadiazine, sulfamerazine and sulfamethazine on different bacterial strains]. | 1968 | Boll. Soc. Ital. Biol. Sper. | pmid:4877331 |
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RychlÃk I and Cerná J | Cross resistance of Escherichia coli B. ribosomes to inhibition of the puromycin reaction by erythromycin, spiramycin and chloramphenicol. | 1968 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:4878426 |
Kiselev RN | [Intestinal microflora in mice and its change under the effect of antibiotics]. | 1968 | Antibiotiki | pmid:4879870 |
Garanin BA | [Sensitivity toward antibiotics of Shigella, isolated rom the patients in years 1960-1965, from the data from Hospital of Infectious Diseases]. | 1968 | Antibiotiki | pmid:4880237 |
Gomez JR and Gomez G | Comparative trial of erythromycin and tetracycline in common infections found in general practice. | 1968 | Br J Clin Pract | pmid:4880249 |
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Frisby BR | A laboratory comparison of tri-acetyl oleandomycin and nine other antibiotics. | 1968 | Med. J. Aust. | pmid:4967052 |
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Lindsay AE and Truxal AC | Oral therapy in bacterial endocarditis. | 1968 | Rocky Mt Med J | pmid:4967211 |
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Woods R | Antibiotic treatment of pyogenic infections of dental origin. | 1968 | Aust Dent J | pmid:5240656 |
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Schonell ME et al. | Disseminated infection with Mycobacterium avium: I. Clinical features, treatment and pathology. | 1968 | Tubercle | pmid:4969143 |
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Saggers BA and Lawson D | In vivo penetration of antibiotics into sputum in cystic fibrosis. | 1968 | Arch. Dis. Child. | pmid:4969417 |
Franco S et al. | Erythromycin in childhood pneumonias. | 1968 | Curr Ther Res Clin Exp | pmid:4969674 |
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Obojska K and Zawadzka-Gralewicz J | [Combined effect of colistin with neomycin, penicillins and erythromycin on Corynebacterium diphtheriae]. | 1968 | Med Dosw Mikrobiol | pmid:4970248 |
Ozawa A | [On the sensitivity of various gram-negative bacilli to demethylchlortetracycline (Ledermycin)]. | 1968 | Jpn J Antibiot | pmid:4974355 |
Malski M | [Effect of penicillin, aureomycin, chloramphenicol and erythromycin on tubercle bacilli]. | 1968 | Gruzlica | pmid:4974660 |
Benzi G et al. | [Effect of erythromycin, various tetracyclines and rifomycin SV, on extrahepatic bile ducts]. | 1968 | Boll Chim Farm | pmid:4976427 |
Wakuta T | Mutual relationship of Candida and Lactobacillus in mixed culture. | 1968 | Bull. Tokyo Med. Dent. Univ. | pmid:4976549 |
Vakulenko NA | [Unification of the method for determination of biological activity of antibiotics by means of single test culture]. | 1968 | Antibiotiki | pmid:4976625 |
Rotheim MB and Ravin AW | Inactivation and reversion of multisite streptomycin resistance mutations of Pneumococcus. | 1968 | Mol. Gen. Genet. | pmid:5713396 |
Onodera T et al. | Effect of fluid and antibiotic administration on experimental fecal peritonitis. | 1968 | Tohoku J. Exp. Med. | pmid:5715596 |
Smith LT et al. | Reproductive performance of pheasant breeder hens. | 1968 | Poult. Sci. | pmid:5716660 |
Velluti G and Grifa P | [In vitro activity of erythromycin on various mycobacterium strains]. | 1968 | G Mal Infett Parassit | pmid:4976935 |
Levy A et al. | [Study "in vitro" and "in vivo" using erythromycin stearate in the therapy of respiratory and cutaneous infections]. | 1968 | Rev Bras Med | pmid:5717048 |
Acocella G et al. | Biliary excretion of antibiotics in man. | 1968 | Gut | pmid:5717103 |
Voors AW and Stewart GT | Statistical analysis of staphylococcal infection in hospital patients in relation to use of antibiotics and other factors. | 1968 | J Hyg (Lond) | pmid:5250128 |
Kanno M et al. | [Study on progressive muscular dystrophy. 1. Influence of the various drugs on serum enzyme activity and the degree of disability]. | 1968 | Iryo | pmid:5717702 |
Schlecht S and Westphal O | [Antibiotic sensitivity in S- and R-forms of Salmonella minnesota]. | 1968 | Naturwissenschaften | pmid:5725584 |
Hejzlar M et al. | Ten-year study of Neisseria gonorrhoeae sensitivity to antibiotics in Czechoslovakia. | 1968 | J Hyg Epidemiol Microbiol Immunol | pmid:4977454 |
Wick WE and Mallett GE | New analysis for the therapeutic efficacy opropionyl erythromycin and erythromycin base. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735386 |
Kuntsevich LD | [Erythromycin and oleandomycin in therapy of fresh gonorrhea in women]. | 1968 | Vestn Dermatol Venerol | pmid:5738081 |
Pezzìca R | [Damage caused by associated antibiotics in domiciliary therapy of acute febrile diseases. Film: "These 3 neutrophil leukocytes are from a 4-year-old child on the fourth day of treatment with CAF in average therapeutic doses. The toxic granulations in the protoplasm are clearly visible"]. | 1968 | Minerva Pediatr. | pmid:5739033 |
Mozziconacci P and Attal C | [Treatment of rheumatic cardiopathies]. | 1968 | Sem Hop | pmid:4307324 |
Renzini G et al. | [Study of the antibacterial activity and of the serum and tissue levels produced in animals by the administration of two antibiotic associations]. | 1968 | Antibiotica | pmid:5740898 |
Cairella M and Marasà G | [The chemoantibiotics in infections of the bile ducts]. | 1968 | Clin Ter | pmid:4982819 |
Studnitsin AA and Pashkov BM | [Results of discussions on the treatment of syphilis]. | 1968 | Vestn Dermatol Venerol | pmid:5742374 |
Martini J et al. | [Treatment of acute male gonococcal urethritis with a single dosis of erythromycin-stearate]. | 1968 | Rev Med Chil | pmid:5746282 |
Mitsui Y and Suzuki H | [Evaluation of colistin-erythromycin ointment and solution in ophthalmology]. | 1968 | Nihon Ganka Kiyo | pmid:5748900 |
Pulverer G | [Studies with lysostaphin. I. Lysostaphin sensitivity of 355 strains of Staph. aureus of human origin]. | 1968 | Z Med Mikrobiol Immunol | pmid:5710870 |
Mao JC and Wiegand RG | Mode of action of macrolides. | 1968 | Biochim. Biophys. Acta | pmid:5649911 |
da Silva WB et al. | [Use of a chloramphenicol-erythromycin combination in the treatment of lung diseases in children]. | 1968 | Hospital (Rio J) | pmid:5308493 |
Puito L | [Antibiotic therapy in infancy]. | 1968 | Pediatria (Napoli) | pmid:4312284 |
Jones PH and Rowley EK | Chemical modifications of erythromycin antibiotics. I. 3'-de(dimethylamino)erythromycin A and B. | 1968 | J. Org. Chem. | pmid:5636610 |
Thomas DY and Wilkie D | Recombination of mitochondrial drug-resistance factors in Saccharomyces cerevisiae. | 1968 | Biochem. Biophys. Res. Commun. | pmid:5637042 |
Petit JF et al. | Biosynthesis of the peptidoglycan of bacterial cell walls. VII. Incorporation of serine and glycine into interpeptide bridges in Staphylococcus epidermidis. | 1968 | J. Biol. Chem. | pmid:5638592 |
Hanley JE et al. | An evaluation and comparison of spectinomycin and spectinomycin-erythromycin combinations for infectious coryza. | 1968 | Avian Dis. | pmid:5643698 |
Breitfellner G et al. | [Staphylococci in the Vienna area. Epidemiology, antibiotic sensitivity and therapeutic aspects]. | 1968 | Wien. Klin. Wochenschr. | pmid:5188335 |
Sotaniemi E and Huhti E | Bronchial asthma and toxic hepatitis. | 1968 | Ann Allergy | pmid:5644356 |
Parisi JT and Suling WJ | Antibiotic resistance of glycine-resistant variants of Staphylococcus aureus. | 1968 | Can. J. Microbiol. | pmid:5188340 |
Desmyter J | Lincomycin resistance of erythromycin-resistant cocci. | 1968 | N. Engl. J. Med. | pmid:5644571 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. I. The experimental typing phage 6557'. | 1968 | Acta Pathol Microbiol Scand | pmid:4231992 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. 2. Characteristics of staphylococci lysed by phage 6557'. | 1968 | Acta Pathol Microbiol Scand | pmid:4231993 |
Breitfellner G and Neuhold R | [Yearly variations of the lysotype and resistance picture of staphylococci]. | 1968 | Wien. Klin. Wochenschr. | pmid:4232544 |
Beck LE | Some recent advances and trends in drug therapy. 2. Antibiotics. | 1968 | Med. J. Aust. | pmid:4233563 |
Jayaraman J and Goldberg IH | Localization of sparsomycin action to the peptide-bond-forming step. | 1968 | Biochemistry | pmid:4921281 |
Herrschaft H | [On the participation of the central nervous system in Behcet's disease]. | 1968 | Dtsch. Med. Wochenschr. | pmid:5655850 |
Ezekiel DH and Elkins BN | The stimulation of ribonucleic acid synthesis by ribosome inhibitors in amino acid-starved Escherichia coli. | 1968 | Biochim. Biophys. Acta | pmid:4234520 |
Biró L and Iván E | Study of bactericidal and bacteriostatic antibiotics in animals with normal and suppressed immunity. | 1968 | Chemotherapy | pmid:5656115 |
Wyman JB et al. | Pancreatic, hepatic, and renal excretion of antibiotics in dogs. Observations on erythromycin, lincomycin, kanamycin, and colistimethate excretion. | 1968 | Arch Surg | pmid:5657416 |
Hashimoto H et al. | Drug resistance of staphylococci. IX. Inducible resistance to macrolide antibiotics in Staphylococcus aureus. | 1968 | Jpn. J. Microbiol. | pmid:4236812 |
Schmitt BD | Indications for tetracycline in pediatrics. | 1968 | Pediatrics | pmid:5657689 |
Forshaw J | Penicillin-induced granulopenia. | 1968 | Br Med J | pmid:5662555 |
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Mezey E et al. | Serum alcohol dehydrogenase, an indicator of intrahepatic cholestasis. | 1968 | N. Engl. J. Med. | pmid:5662777 |
The macrolides and lincomycin. | 1968 | Br Med J | pmid:5662980 | |
Simon C and Latz E | [Antibiotic therapy of staphylococcal infections. The influence of chloramphenicol and erythromycin on the bactericidal effect of penicillin G and methicillin in vitro]. | 1968 | Med Welt | pmid:5663162 |
Narasimhan MJ and Ganla VG | The broad-spectrum and the macrolide antibiotics and the ciliary barrier. | 1968 | Hindustan Antibiot Bull | pmid:5663533 |
Bertrand JL | [Combination of propionyl-erythromycin, tetracycline and lysozyme in anti-infective therapy in adults and children]. | 1968 | Lyon Med | pmid:5664960 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. 3. Occurrence and spread of "type 6557", with special reference to the consumption of some antibiotics. | 1968 | Acta Pathol Microbiol Scand | pmid:4244485 |
Lamb AJ et al. | The biogenesis of mitochondria. 4. The differentiation of mitochondrial and cytoplasmic protein synthesizing systems in vitro by antibiotics. | 1968 | Biochim. Biophys. Acta | pmid:5667290 |
Davis CM et al. | The value of neomycin in a neomycin-steroid cream. | 1968 | JAMA | pmid:4294840 |
Rodovalho SF | [Tolerance and efficiency of erythromycin suppositories used in respiratory infections in ambulatory pediatric practice]. | 1968 | Hospital (Rio J) | pmid:5306207 |
Weisblum B and Davies J | Antibiotic inhibitors of the bacterial ribosome. | 1968 | Bacteriol Rev | pmid:4179192 |
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Ivanitskaia LP and Manafova NA | [Study of sensitivity to antibiotics in cultures of Anacystis nidulans and Chlorella sp. in relation to their possible use as tests in selection of new biologically active compounds from Actinomycetes]. | 1968 | Antibiotiki | pmid:4180805 |
Hirasawa K | [Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders]. | 1968 | Jpn. Circ. J. | pmid:4299837 |
Alterio DL | [Clinico-parasitological evaluation of an anti-ameba therapeutic activity of a new non-absorbable erythromycin stearate preparation]. | 1968 | Hospital (Rio J) | pmid:5307504 |
Ganança MM | [Use of erythromycin suppositories in the treatment of otorhinolaryngologic infections in children]. | 1968 | Hospital (Rio J) | pmid:5307873 |
Barnes RW et al. | Studies of sterility of calf venous blood. | 1968 | Surgery | pmid:4300855 |
Dohlman CH and Boruchoff SA | Penetrating keratoplasty. | 1968 | Int Ophthalmol Clin | pmid:4904228 |
Ruczaj Z | Sensitivity of microorganisms to antibiotics produced by them. | 1968 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:4302938 |
Siegenthaler W et al. | [New antibiotics, with the exception of penicillins, streptomycin, tetracyclines and chloramphenicol]. | 1968 | Antibiot Chemother | pmid:4302993 |
Minkova GL | [On the sensitivity of microflora of burn wounds to antibiotics]. | 1968 | Antibiotiki | pmid:4305269 |
Baskanchiladze GSh and Buniatova IM | [Change in the sensitivity to antibiotics of pathogenic staphylococci, isolated in Tiflis during 1961-1966]. | 1968 | Antibiotiki | pmid:4303353 |