erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stang EM and White MC | On the macrocyclization of the erythromycin core: preorganization is not required. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21344559 |
Qin SS et al. | Antimicrobial resistance in Campylobacter coli isolated from pigs in two provinces of China. | 2011 | Int. J. Food Microbiol. | pmid:21349598 |
Song M et al. | Antibiotic susceptibility of Propionibacterium acnes isolated from acne vulgaris in Korea. | 2011 | J. Dermatol. | pmid:21352337 |
Liu BY et al. | Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum. | 2011 | Ecotoxicol. Environ. Saf. | pmid:21353704 |
Crivellaro S et al. | Surveillance of methicillin-resistant Staphylococcus aureus isolated in Torino (northwest Italy). | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21353947 |
Kafali H et al. | Recurrence of ovarian cyst after sclerotherapy. | 2011 | Minerva Ginecol | pmid:21311417 |
Shang Y et al. | Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis. | 2011 | Chin. Med. J. | pmid:21362305 |
Pateron D et al. | Erythromycin infusion or gastric lavage for upper gastrointestinal bleeding: a multicenter randomized controlled trial. | 2011 | Ann Emerg Med | pmid:21333385 |
Cai XJ et al. | [Protective effects of erythromycin on human bronchial epithelial cells impaired by interleukin-4]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:22094097 |
Otsu K et al. | Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. | 2011 | Pharmacology | pmid:22116077 |
Thenmozhi R et al. | Characterization of biofilms in different clinical M serotypes of Streptococcus pyogenes. | 2011 | J. Basic Microbiol. | pmid:21298675 |
Tosin M et al. | In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines. | 2011 | Chem. Commun. (Camb.) | pmid:21301753 |
Mingoia M et al. | Heterogeneity of Tn5253-like composite elements in clinical Streptococcus pneumoniae isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:21263055 |
Werner CR et al. | [Unexpected complication following esophageal variceal hemorrhage - Case 2/2011]. | 2011 | Dtsch. Med. Wochenschr. | pmid:21271486 |
Wright AJ et al. | The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers. | 2011 | CMAJ | pmid:21242274 |
Zhang L et al. | Synthesis and antibacterial activity of new 4″-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether. | 2011 | J. Antibiot. | pmid:21245870 |
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Belousoff MJ et al. | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21282615 |
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Lubell Y et al. | Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. | 2011 | Trop. Med. Int. Health | pmid:21740488 |
Spigaglia P et al. | Multidrug resistance in European Clostridium difficile clinical isolates. | 2011 | J. Antimicrob. Chemother. | pmid:21771851 |
Jupelli M et al. | Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life. | 2011 | Lab. Invest. | pmid:21769086 |
Clifford V et al. | Variation in erythromycin and clindamycin resistance patterns between New Zealand and Australian group B streptococcus isolates. | 2011 | Aust N Z J Obstet Gynaecol | pmid:21806568 |
Nielsen EI et al. | Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization. | 2011 | Antimicrob. Agents Chemother. | pmid:21807983 |
Gardner L et al. | Photochemical control of bacterial signal processing using a light-activated erythromycin. | 2011 | Mol Biosyst | pmid:21785768 |
DeDea L | Erythromycin for GI motility; sunscreens; enoxaparin in obesity. | 2011 | JAAPA | pmid:21850912 |
Maeda Y et al. | Comparison of minimum inhibitory concentration by broth microdilution testing versus standard disc diffusion testing in the detection of penicillin, erythromycin and ciprofloxacin resistance in viridans group streptococci. | 2011 | J. Med. Microbiol. | pmid:21852527 |
Chen Y et al. | Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. | 2011 | Drug Metab. Dispos. | pmid:21835977 |
Ahmetagic A et al. | Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. | 2011 | Plasmid | pmid:21839110 |
Liu Y et al. | The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21570844 |
Samra Z et al. | Susceptibility of Ureaplasma urealyticum to tetracycline, doxycycline, erythromycin, roxithromycin, clarithromycin, azithromycin, levofloxacin and moxifloxacin. | 2011 | J Chemother | pmid:21571622 |
Bistrian BR | Enteral feeding: good, but not for everyone. | 2011 | Crit. Care Med. | pmid:21613857 |
Bai Y et al. | Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding. | 2011 | Aliment. Pharmacol. Ther. | pmid:21615438 |
Ergin A et al. | Erythromycin and penicillin resistance mechanisms among viridans group streptococci isolated from blood cultures of adult patients with underlying diseases. | 2011 | New Microbiol. | pmid:21617831 |
Garber NC et al. | Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol. | 2011 | Adv. Exp. Med. Biol. | pmid:21618111 |
Sugiyama E et al. | The use of 13C-erythromycin as an in vivo probe to evaluate CYP3A-mediated drug interactions in rats. | 2011 | J Pharm Sci | pmid:21618542 |
Qin X et al. | Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. | 2011 | Int. J. Antimicrob. Agents | pmid:21549571 |
Sigaroudinia MO and Quayle AR | Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. | 2011 | Surgeon | pmid:21550524 |
Öberg AI et al. | β-Adrenergic inhibition of contractility in L6 skeletal muscle cells. | 2011 | PLoS ONE | pmid:21829455 |
Osman M and Ghosh SK | Semiparametric bayesian testing procedure for noninferiority trials with binary endpoints. | 2011 | J Biopharm Stat | pmid:21830923 |
Baronsky J et al. | Perfusion calorimetry in the characterization of solvates forming isomorphic desolvates. | 2011 | Eur J Pharm Sci | pmid:21726637 |
Dixon-Woods M et al. | Providing the results of research to participants: a mixed-method study of the benefits and challenges of a consultative approach. | 2011 | Clin Trials | pmid:21730081 |
Akshay S et al. | Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. | 2011 | Antimicrob. Agents Chemother. | pmid:21730122 |
Pannu J et al. | In vitro antibacterial activity of NB-003 against Propionibacterium acnes. | 2011 | Antimicrob. Agents Chemother. | pmid:21746943 |
Daram SR and Garretson R | Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding. | 2011 | Gastrointest. Endosc. | pmid:21704823 |
Ma X et al. | Novel C-4'' modified azithromycin analogs with remarkably enhanced activity against erythromycin-resistant Streptococcus pneumoniae: the synthesis and antimicrobial evaluation. | 2011 | Eur J Med Chem | pmid:21855183 |
Soehnlen MK et al. | In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method. | 2011 | J. Vet. Diagn. Invest. | pmid:21908288 |
Albarellos GA et al. | Pharmacokinetics of erythromycin after intravenous, intramuscular and oral administration to cats. | 2011 | Vet. J. | pmid:19854664 |
Brodesser S and Kolter T | Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes. | 2011 | J Lipids | pmid:21490810 |
Motoyama M et al. | Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level. | 2011 | Chemosphere | pmid:21570103 |
Boghigian BA et al. | Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21487833 |
Spurling GK et al. | Antibiotics for bronchiolitis in children. | 2011 | Cochrane Database Syst Rev | pmid:21678346 |
Matsson EM et al. | Biliary excretion of ximelagatran and its metabolites and the influence of erythromycin following intraintestinal administration to healthy volunteers. | 2011 | J Clin Pharmacol | pmid:20663994 |
Bonofiglio L et al. | Dissemination of an erythromycin-resistant penicillin-nonsusceptible Streptococcus pneumoniae Poland(6B)-20 clone in Argentina. | 2011 | Microb. Drug Resist. | pmid:21128835 |
Zanoni RG et al. | Occurrence of Helicobacter pullorum in turkeys. | 2011 | Vet. Microbiol. | pmid:21144678 |
Altraif I et al. | Effect of erythromycin before endoscopy in patients presenting with variceal bleeding: a prospective, randomized, double-blind, placebo-controlled trial. | 2011 | Gastrointest. Endosc. | pmid:21145052 |
Bopp LH et al. | Activities of tigecycline and comparators against Legionella pneumophila and Legionella micdadei extracellularly and in human monocyte-derived macrophages. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21146719 |
Braga TM et al. | Involvement, and dissemination, of the enterococcal small multidrug resistance transporter QacZ in resistance to quaternary ammonium compounds. | 2011 | J. Antimicrob. Chemother. | pmid:21147826 |
Allen VG et al. | Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. | 2011 | Antimicrob. Agents Chemother. | pmid:21098249 |
Miller E et al. | Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study. | 2011 | Lancet Infect Dis | pmid:21621466 |
Song W et al. | A novel strontium-doped calcium polyphosphate/erythromycin/poly(vinyl alcohol) composite for bone tissue engineering. | 2011 | J Biomed Mater Res A | pmid:21626667 |
Wingard JB et al. | A novel cell-associated protection assay demonstrates the ability of certain antibiotics to protect ocular surface cell lines from subsequent clinical Staphylococcus aureus challenge. | 2011 | Antimicrob. Agents Chemother. | pmid:21628536 |
Amachawadi RG et al. | Selection of fecal enterococci exhibiting tcrB-mediated copper resistance in pigs fed diets supplemented with copper. | 2011 | Appl. Environ. Microbiol. | pmid:21705534 |
Tanamachi C et al. | [A case of Desulfovibrio desulfuricans cultured from blood in Japan]. | 2011 | Rinsho Byori | pmid:21706860 |
Mikura S et al. | Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. | 2011 | Transl Res | pmid:21708354 |
Richter SS et al. | Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. | 2011 | Antimicrob. Agents Chemother. | pmid:21709080 |
Feneran AN et al. | Retinoid plus antimicrobial combination treatments for acne. | 2011 | Clin Cosmet Investig Dermatol | pmid:21760743 |
Mueller DH et al. | Constraints to implementing the Essential Health Package in Malawi. | 2011 | PLoS ONE | pmid:21695115 |
Ma L et al. | Green fluorescent protein labeling of Listeria, Salmonella, and Escherichia coli O157:H7 for safety-related studies. | 2011 | PLoS ONE | pmid:21483738 |
Xiong L et al. | Lignans and neolignans from Sinocalamus affinis and their absolute configurations. | 2011 | J. Nat. Prod. | pmid:21469695 |
Lobanov KV et al. | Reconstruction of Purine Metabolism in Bacillus subtilis to Obtain the Strain Producer of AICAR: A New Drug with a Wide Range of Therapeutic Applications. | 2011 | Acta Naturae | pmid:22649686 |
Aknin LB et al. | It's the recipient that counts: spending money on strong social ties leads to greater happiness than spending on weak social ties. | 2011 | PLoS ONE | pmid:21347326 |
Filić D et al. | Crystal structure and physicochemical properties of crystalline form of 2'-O-{3-[(7-chloro-4-quinolinyl)amino]propyl}-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A. | 2011 | J Pharm Sci | pmid:21394721 |
van den Bosch S et al. | Erythromycin to promote bedside placement of a self-propelled nasojejunal feeding tube in non-critically ill patients having pancreatitis: a randomized, double-blind, placebo-controlled study. | 2011 | Nutr Clin Pract | pmid:21447772 |
Wang SM et al. | Clinical significance of erythromycin-resistant Campylobacter jejuni in children. | 2011 | J Microbiol Immunol Infect | pmid:21531355 |
Louvet JN et al. | Simultaneous Gram and viability staining on activated sludge exposed to erythromycin: 3D CLSM time-lapse imaging of bacterial disintegration. | 2011 | Int J Hyg Environ Health | pmid:21420358 |
Serdoz F et al. | Development and pharmacokinetic evaluation of erythromycin lipidic formulations for oral administration in rainbow trout (Oncorhynchus mykiss). | 2011 | Eur J Pharm Biopharm | pmid:21402156 |
Marjanović N et al. | Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro. | 2011 | Pharmacol. Res. | pmid:21315154 |
Siibak T et al. | Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins. | 2011 | Mol. Microbiol. | pmid:21320180 |
Veiga-Crespo P et al. | Synergism between outer membrane proteins and antimicrobials. | 2011 | Antimicrob. Agents Chemother. | pmid:21321143 |
Dinh QT et al. | Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. | 2011 | Talanta | pmid:21807177 |
Dow GS et al. | Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice. | 2011 | Malar. J. | pmid:21645370 |
Pignatello R et al. | Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. | 2011 | AAPS PharmSciTech | pmid:21479751 |
Keelan JA et al. | Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. | 2011 | Am. J. Obstet. Gynecol. | pmid:21481833 |
Fan C and He J | Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. | 2011 | Water Res. | pmid:21482429 |
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Justa RF et al. | Bacillary angiomatosis in HIV-positive patient from Northeastern Brazil: a case report. | 2011 | Rev. Soc. Bras. Med. Trop. | pmid:22031085 |
Jakeman DL and Sadeghi-Khomami A | A β-(1,2)-glycosynthase and an attempted selection method for the directed evolution of glycosynthases. | 2011 | Biochemistry | pmid:22035228 |
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Gray KL et al. | The outpatient institutional antibiogram does not accurately reflect the susceptibility of prepartum group B streptococcal isolates to erythromycin and clindamycin. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21982562 |
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Sugawara A et al. | Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21524580 |
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Ando F et al. | Synergic effects of β-estradiol and erythromycin on hERG currents. | 2011 | J. Membr. Biol. | pmid:21484263 |
Flaman AS et al. | The effect of interferon-α on the expression of cytochrome P450 3A4 in human hepatoma cells. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21466820 |
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Liu L et al. | Disappearance of sexual dimorphism in triptolide metabolism in monosodium glutamate treated neonatal rats. | 2011 | Arzneimittelforschung | pmid:21428244 |
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