erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pasquini L et al. | Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. | 2014 | Sci. Total Environ. | pmid:24631609 |
| Hirsch R et al. | Occurrence of antibiotics in the aquatic environment. | 1999 | Sci. Total Environ. | pmid:10028708 |
| Liu J et al. | Tissue distribution, bioconcentration, metabolism, and effects of erythromycin in crucian carp (Carassius auratus). | 2014 | Sci. Total Environ. | pmid:24911771 |
| Pasquini L et al. | Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. | 2013 | Sci. Total Environ. | pmid:23827359 |
| Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
| GOODGAL SH and POSTEL EH | NITROUS ACID MUTATION OF TRANSFORMING DNA: CONSIDERATION OF MODE OF ACTION. | 1965 | Science | pmid:14289610 |
| Tanaka K et al. | Erythromycin-resistant mutant of Escherichia coli with altered ribosomal protein component. | 1968 | Science | pmid:4886608 |
| Cortes J et al. | Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage. | 1995 | Science | pmid:7770773 |
| GUZE LB and KALMANSON GM | ACTION OF ERYTHROMYCIN ON "PROTOPLASTS" IN VIVO. | 1964 | Science | pmid:14207454 |
| WOLFE AD and HAHN FE | ERYTHROMYCIN: MODE OF ACTION. | 1964 | Science | pmid:14107448 |
| Cane DE | Polyketide biosynthesis: molecular recognition or genetic programming? | 1994 | Science | pmid:8278806 |
| Marsden AF et al. | Stereospecific acyl transfers on the erythromycin-producing polyketide synthase. | 1994 | Science | pmid:8278811 |
| Mets LJ and Bogorad L | Mendelian and uniparental alterations in erythromycin binding by plastid ribosomes. | 1971 | Science | pmid:5123420 |
| PERLMAN D | Colorimetric method for determination of aureomycin, carbomycin, erythromycin, and terramycin in aqueous solution. | 1953 | Science | pmid:13113207 |
| Donadio S et al. | Modular organization of genes required for complex polyketide biosynthesis. | 1991 | Science | pmid:2024119 |
| Kao CM et al. | Engineered biosynthesis of a complete macrolactone in a heterologous host. | 1994 | Science | pmid:8036492 |
| Jacobsen JR et al. | Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase. | 1997 | Science | pmid:9219693 |
| Service RF | Hijacking a cell's chemical paths to make new antibiotics. | 1997 | Science | pmid:9518361 |
| Oldenburg M et al. | TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. | 2012 | Science | pmid:22821982 |
| D'Costa VM et al. | Sampling the antibiotic resistome. | 2006 | Science | pmid:16424339 |
| Pfeifer BA et al. | Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli. | 2001 | Science | pmid:11230695 |
| Weber JM et al. | An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea. | 1991 | Science | pmid:2011746 |
| Feighner SD et al. | Receptor for motilin identified in the human gastrointestinal system. | 1999 | Science | pmid:10381885 |
| HUGHES DW and DIAMOND LK | CHLORAMPHENICOL IN BLOOD: SIMPLE CHEMICAL ESTIMATIONS IN PATIENTS RECEIVING MULTIPLE ANTIBIOTICS. | 1964 | Science | pmid:14169715 |
| Sachs MS and Geballe AP | Biochemistry. Sense and sensitivity--controlling the ribosome. | 2002 | Science | pmid:12228706 |
| GRIFFITH LJ et al. | DRUG ANTAGONISM BETWEEN LINCOMYCIN AND ERYTHROMYCIN. | 1965 | Science | pmid:14242023 |
| Marsden AF et al. | Engineering broader specificity into an antibiotic-producing polyketide synthase. | 1998 | Science | pmid:9422686 |
| Shen Y et al. | Mitigative effect of erythromycin on PMMA challenged preosteoblastic MC3T3-E1 cells. | 2014 | ScientificWorldJournal | pmid:25110723 |
| Avian tuberculosis. | 1968 | Scott Med J | pmid:4884700 | |
| Williams RF | The problems, diagnosis and treatment of infection by Staphylococcus aureus. | 1979 | Scott Med J | pmid:493932 |
| Ford MJ et al. | Mycoplasma pneumonia: failure of erythromycin therapy. | 1980 | Scott Med J | pmid:7455669 |
| Lacey RW | Do bacteria mutate to erythromycin resistance? | 1977 | Scott Med J | pmid:23582 |
| Jones GR and Stewart SM | A prospective study of the persistence of Mycoplasma pneumoniae antibody levels. | 1974 | Scott Med J | pmid:4597913 |
| Watt B | Erythromycin and anaerobes: in vitro aspects. | 1977 | Scott Med J | pmid:341310 |
| Gould JC | Erythromycin symposium: introduction. | 1977 | Scott Med J | pmid:601552 |
| McC Murdoch J | A short review of erythromycin. | 1977 | Scott Med J | pmid:601553 |
| Watson GI | The treatment of Mycoplasma pneumoniae infections. | 1977 | Scott Med J | pmid:601554 |
| Forfar JO | Erythromycin resistance in neonatal staphylococcal infection: a long-term survey. | 1977 | Scott Med J | pmid:601556 |
| Lambert HP | Erythromycin and anaerobic infection. | 1977 | Scott Med J | pmid:601557 |
| Knothe H and Dette GA | Pharmakokinetics of erythromycin. | 1977 | Scott Med J | pmid:601558 |
| Ruhrmann G and Holthusen W | Mycoplasma infection and erythromycin therapy in childhood. | 1977 | Scott Med J | pmid:601559 |
| Grob PR | The use of erythromycin in a general practice. | 1977 | Scott Med J | pmid:601560 |
| Oriel JD et al. | Comparison of erythromycin stearate and oxytetracycline in the treatment of non-gonococcal urethritis: their efficacy against Chlamydia trachomatis. | 1977 | Scott Med J | pmid:601555 |
| MACCABE AF and GOULD JC | The epidemiology of an erythromycin resistant Staphylococcus. | 1956 | Scott Med J | pmid:13351658 |
| Edmond E et al. | Avian tuberculosis. | 1968 | Scott Med J | pmid:5751239 |
| SYME J et al. | Studies with monopropionyl erythromycin. | 1961 | Scott Med J | pmid:13774375 |
| Gould JC | Erythromycin in respiratory tract infection. | 1977 | Scott Med J | pmid:414355 |
| GIBSON GL | Erythromycin-resistant Staphylococcus pyogenes; report of five cases. | 1958 | Scott Med J | pmid:13529051 |
| Hardie R and Hardie RA | Leg ulcer infection with an erythromycin-resistant Streptococcus pyogenes. | 1986 | Scott Med J | pmid:3515552 |
| Cao Z et al. | [Analysis of erythromycin A oxime and its related compounds by RP-HPLC on base-deactivated column]. | 2007 | Se Pu | pmid:18257324 |
| Adachi T and Morimoto S | [A new macrolide antibiotic, clarithromycin--synthesis, structure-activity relationship and metabolism]. | 1990 | Seikagaku | pmid:2150202 |
| Vincent M and Brune J | [4 cases of Mycoplasma pneumoniae pneumonia]. | 1982 | Sem Hop | pmid:6297021 |
| Colin JY et al. | [Acute perihepatitis of genital origin (Fitz Hugh-Curtis syndrome): 4 case reports]. | 1982 | Sem Hop | pmid:6297042 |
| Becq-Giraudon B et al. | [Acute respiratory distress syndrome: indigenous Legionnaires' disease (author's transl)]. | 1981 Mar 8-15 | Sem Hop | pmid:6261396 |
| Groussin P et al. | [Value of a therapeutic test in Whipple's disease. Apropos of 1 case]. | 1976 | Sem Hop | pmid:63148 |
| CLUZEL R et al. | [Combination erythromycin-oleandomycin: favorable bactericidal effect on pathogenic staphylococci]. | 1959 | Sem Hop | pmid:13624776 |
| Mozziconacci P and Attal C | [Treatment of rheumatic cardiopathies]. | 1968 | Sem Hop | pmid:4307324 |
| Loire R et al. | [Present developmental aspect of infectious endocarditis. According to hospital statistics of 103 consecutive cases collected in the last 12 years]. | 1969 | Sem Hop | pmid:4308671 |
| Amblard P et al. | [The association tretinoin-erythromycin base: a new topical treatment for acne. Results of a multicentric trial on 347 cases (authors transl)]. | 1980 May 8-15 | Sem Hop | pmid:6248979 |
| RADERMECKER M and REGINSTER M | [STEVENS-JOHNSON SYNDROME AND ALLERGIC PAROTIDITIS. CONTRIBUTION TO ITS ETIOPATHOGENIC STUDY]. | 1964 | Sem Hop | pmid:14176724 |
| Satgé P et al. | [Generalized infections by Candida albicans in children (apropos of 17 cases)]. | 1967 | Sem Hop | pmid:4296493 |
| LAPERUTA AM et al. | [CLINICAL EXPERIENCE WITH D.A.T.C]. | 1964 | Sem Med | pmid:14181017 |
| Timsit E | [Results obtained with erythromycin stearate in the treatment of acnes]. | 1967 Jun-Jul | Sem Ther | pmid:4240940 |
| Del Bene VE and Farrar WE | Antimicrobial therapy of infections due to anaerobic bacteria. | 1972 | Semin Drug Treat | pmid:4617925 |
| Widdowson CA and Klugman KP | Molecular mechanisms of resistance to commonly used non-betalactam drugs in Streptococcus pneumoniae. | 1999 | Semin Respir Infect | pmid:10501313 |
| Gump DW and Keegan M | Pulmonary infections due to Legionella in immunocompromised patients. | 1986 | Semin Respir Infect | pmid:3317608 |
| Kirby BD and Harris AA | Nosocomial Legionnaires' disease. | 1987 | Semin Respir Infect | pmid:3328895 |
| Keys TF | Therapeutic considerations in the treatment of Legionella infections. | 1987 | Semin Respir Infect | pmid:3328898 |
| Anderson EL | Prevention of pertussis. | 1989 | Semin Respir Infect | pmid:2560581 |
| Chitturi S and Farrell GC | Drug-induced cholestasis. | 2001 | Semin. Gastrointest. Dis. | pmid:11352118 |
| King PD and Blitzer BL | Drug-induced cholestasis: pathogenesis and clinical features. | 1990 | Semin. Liver Dis. | pmid:2281339 |
| Bell TA | Chlamydia trachomatis, Mycoplasma hominis, and Ureaplasma urealyticum infections of infants. | 1985 | Semin. Perinatol. | pmid:3881828 |
| Mercer BM et al. | What we have learned regarding antibiotic therapy for the reduction of infant morbidity after preterm premature rupture of the membranes. | 2003 | Semin. Perinatol. | pmid:12889589 |
| Andrews WW and Goldenberg RL | What we have learned from an antibiotic trial in fetal fibronectin positive women. | 2003 | Semin. Perinatol. | pmid:12889590 |
| Schelonka RL and Waites KB | Ureaplasma infection and neonatal lung disease. | 2007 | Semin. Perinatol. | pmid:17317421 |
| Ariga K et al. | Intelligent chiral sensing based on supramolecular and interfacial concepts. | 2010 | Sensors (Basel) | pmid:22163577 |
| Havlichek DH et al. | Comparison of chlamydial culture with Chlamydiazyme assay during erythromycin PCE treatment of Chlamydia genital infections. | 1990 Jan-Mar | Sex Transm Dis | pmid:2406958 |
| D'Souza P et al. | A comparative study of therapeutic response of patients with clinical chancroid to ciprofloxacin, erythromycin, and cotrimoxazole. | 1998 | Sex Transm Dis | pmid:9662762 |
| Hashisaki P et al. | Erythromycin failure in the treatment of syphilis in a pregnant woman. | 1983 Jan-Mar | Sex Transm Dis | pmid:6601848 |
| Osser S and Persson K | Postabortal infectious morbidity after antibiotic treatment of chlamydia-positive patients. | 1989 Apr-Jun | Sex Transm Dis | pmid:2740963 |
| Moodley P et al. | Association between HIV-1 infection, the etiology of genital ulcer disease, and response to syndromic management. | 2003 | Sex Transm Dis | pmid:12616144 |
| Papadimos TJ et al. | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from a military population in San Diego. | 1988 Oct-Dec | Sex Transm Dis | pmid:2976208 |
| The National Gonorrhea Therapy Monitoring Study: II. Trends and seasonality of antibiotic resistance of Neisseria gonorrhoeae. | 1979 Apr-Jun | Sex Transm Dis | pmid:158832 | |
| Goodhart GL | Treatment of uncomplicated genital gonorrhea. | 1979 Apr-Jun | Sex Transm Dis | pmid:158833 |
| Goodrich JT | Treatment of gonorrhea in pregnancy. | 1979 Apr-Jun | Sex Transm Dis | pmid:158835 |
| Ehret JM et al. | A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. | 1996 Jul-Aug | Sex Transm Dis | pmid:8836018 |
| Tyndall MW et al. | Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. | 1994 Jul-Aug | Sex Transm Dis | pmid:7974076 |
| Linnemann CC et al. | Treatment of Chlamydia trachomatis infections: comparison of 1- and 2-g doses of erythromycin daily for seven days. | 1987 Apr-Jun | Sex Transm Dis | pmid:3616850 |
| Oriel JD et al. | Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. | 1982 Oct-Dec | Sex Transm Dis | pmid:6821502 |
| Fiumara NJ | Review of congenital syphilis. | 1984 Jan-Mar | Sex Transm Dis | pmid:6710286 |
| Scheibel JH et al. | Treatment of chlamydial urethritis in men and Chlamydia trachomatis-positive female partners: comparison of erythromycin and tetracycline in treatment courses of one week. | 1982 Jul-Sep | Sex Transm Dis | pmid:7147151 |
| Carpenter JL et al. | Treatment of chancroid with erythromycin. | 1981 Jul-Sep | Sex Transm Dis | pmid:6974899 |
| Bindayna KM et al. | Chromosomal resistance to antibiotics in gonococci from Bahrain. | 1991 Jul-Sep | Sex Transm Dis | pmid:1948513 |
| Rahangdale L et al. | An observational cohort study of Chlamydia trachomatis treatment in pregnancy. | 2006 | Sex Transm Dis | pmid:16432482 |
| De Munain JL et al. | Two lymphogranuloma venereum cases in a heterosexual couple in Bilbao (Spain). | 2008 | Sex Transm Dis | pmid:18641534 |
| Noble RC and Parekh MC | Susceptibility of different auxotypes of Neisseria gonorrhoeae to norfloxacin, cefotaxime, cefuroxime, and erythromycin. | 1984 Jul-Sep | Sex Transm Dis | pmid:6095474 |
| Brayden RM et al. | Chlamydial pneumonia of infancy in siblings. | 1988 Oct-Dec | Sex Transm Dis | pmid:3227475 |
| Bell TA et al. | Comparison of ophthalmic silver nitrate solution and erythromycin ointment for prevention of natally acquired Chlamydia trachomatis. | 1987 Oct-Dec | Sex Transm Dis | pmid:3438783 |
| Givan KF and Jaeger R | Auxotypes of Neisseria gonorrhoeae isolated from heterosexual men, homosexual men, and heterosexual women. | 1986 Jan-Mar | Sex Transm Dis | pmid:3082017 |
| Pace PJ and Catlin BW | Characteristics of Neisseria gonorrhoeae strains isolated on selective and nonselective media. | 1986 Jan-Mar | Sex Transm Dis | pmid:3082019 |