erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Critical Illness D016638 13 associated lipids
Bursitis D002062 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Acute Lung Injury D055371 33 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Rosacea D012393 13 associated lipids
Pericarditis D010493 6 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Heart Block D006327 3 associated lipids
Long QT Syndrome D008133 10 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Gonorrhea D006069 7 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Endometritis D004716 6 associated lipids
Vibrio Infections D014735 5 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Radiodermatitis D011855 3 associated lipids
Constipation D003248 8 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Varicose Ulcer D014647 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Pityriasis D010915 3 associated lipids
Xerostomia D014987 6 associated lipids
Hand Dermatoses D006229 5 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Ergotism D004881 4 associated lipids
Liver Abscess D008100 6 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Torsades de Pointes D016171 2 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Splenomegaly D013163 4 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Endocarditis D004696 4 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Gastroparesis D018589 2 associated lipids
Dyspepsia D004415 5 associated lipids
Asthenia D001247 5 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Tooth Diseases D014076 2 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Tourette Syndrome D005879 3 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Peptic Ulcer Hemorrhage D010438 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Bronchiectasis D001987 7 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Parotitis D010309 4 associated lipids
Dysarthria D004401 2 associated lipids
Lyme Disease D008193 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Bile Reflux D001655 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Animal Diseases D000820 2 associated lipids
Legionellosis D007876 3 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Blepharitis D001762 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Toothache D014098 3 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Pleuropneumonia D011001 3 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Intestinal Atresia D007409 3 associated lipids
Foot Ulcer D016523 4 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Balanitis D001446 4 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Faghin R et al. Acid degradation studies of 6-deoxyerythromycin A. 1993 J. Antibiot. pmid:8501017
Oğünç G et al. [Legionnaires' disease following kidney transplantation]. 1993 Mikrobiyol Bul pmid:8502185
Sacristán JA et al. Ototoxicity of erythromycin in man: electrophysiologic approach. 1993 Am J Otol pmid:8503495
Danielson ND et al. Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. 1993 J Pharm Biomed Anal pmid:8504183
Altemeir WA and Ayoub EM Erythromycin prophylaxis for pertussis. 1977 Pediatrics pmid:850603
Lemaire F et al. [Erythromycin therapy of incidences of superinfection in chronic respiratory insufficiency]. 1977 Nouv Presse Med pmid:850633
Kawamura O et al. Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract. 1993 Dig. Dis. Sci. pmid:8508696
Roberts GA et al. Heterologous expression in Escherichia coli of an intact multienzyme component of the erythromycin-producing polyketide synthase. 1993 Eur. J. Biochem. pmid:8508800
Varga DW Learning in the real world. 1993 J Ky Med Assoc pmid:8509688
Siminoski K Persistent fever due to occult dental infection: case report and review. 1993 Clin. Infect. Dis. pmid:8513063
Suata K et al. Antimicrobial susceptibility patterns and resistance transferability among Bacteroides fragilis group isolates from patients with appendicitis in Bali, Indonesia. 1993 Clin. Infect. Dis. pmid:8513066
Narchi P et al. Interactions of pre-operative erythromycin administration with general anaesthesia. 1993 Can J Anaesth pmid:8513524
Kepczyk T et al. Effect of intravenous erythromycin on gastric emptying. 1993 May-Jun Gastrointest. Endosc. pmid:8514093
Nakata M et al. Synthetic studies of erythromycin derivatives. Synthesis and antimicrobial activities of 3''-EPI-erythromycin A and (9S)-11-dehydroxy-9-deoxo-9-hydroxy-11- oxoerythromycin A. 1993 J. Antibiot. pmid:8514636
Suriñach JM et al. [Acute pancreatitis from erythromycin]. 1993 Rev Clin Esp pmid:8516513
Baird RM Antimicrobial drug use in hospitals. 1977 Can Med Assoc J pmid:851926
González Carro P et al. [Acute pancreatitis and erythromycin]. 1995 Rev Esp Enferm Dig pmid:8519548
Kelentey BA and Kelentey BJ [Excretion of erythromycin, clindamycin and lincomycin into the saliva]. 1995 Fogorv Sz pmid:8522016
Tee W et al. Emergence of multidrug resistance in Campylobacter jejuni isolates from three patients infected with human immunodeficiency virus. 1995 Clin. Infect. Dis. pmid:8527556
Lestico MR and Smith AD Stevens-Johnson syndrome following erythromycin administration. 1995 Am J Health Syst Pharm pmid:8528839
Benzamycin gel for acne. 1995 Drug Ther Bull pmid:8529541
Izumikawa K et al. [The therapeutic effect of doxycycline (Vibramycin) on pneumonia due to mycoplasma pneumoniae (author's transl)]. 1977 Jpn J Antibiot pmid:853569
Hoppe JE and Tschirner T Comparison of media for agar dilution susceptibility testing of Bordetella pertussis and Bordetella parapertussis. 1995 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8536725
Shiba Y et al. Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs. 1996 Gastroenterology pmid:8536863
Doucet-Populaire F et al. Acquired resistance in Mycobacterium avium complex strains isolated from AIDS patients and beige mice during treatment with clarithromycin. 1995 J. Antimicrob. Chemother. pmid:8537260
Hosie J et al. A comparison of 5 days of dirithromycin and 7 days of clarithromycin in acute bacterial exacerbation of chronic bronchitis. 1995 J. Antimicrob. Chemother. pmid:8537264
Littenberg B et al. A randomized controlled trial of oral albuterol in acute cough. 1996 J Fam Pract pmid:8537805
Pechère JC [Effect of the molecular structure of azithromycin on pharmacokinetics and the antimicrobial activity]. 1995 Pathol. Biol. pmid:8539069
Philippon A et al. [Azithromycin: critical points]. 1995 Pathol. Biol. pmid:8539070
Lagrange PH [Azithromycin, pharmacodynamic evaluation in animal models]. 1995 Pathol. Biol. pmid:8539074
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Tissi L et al. In vivo efficacy of azithromycin in treatment of systemic infection and septic arthritis induced by type IV group B Streptococcus strains in mice: comparative study with erythromycin and penicillin G. 1995 Antimicrob. Agents Chemother. pmid:8540695
Kenney DG et al. Development of reactive arthritis and resistance to erythromycin and rifampin in a foal during treatment for Rhodococcus equi pneumonia. 1994 Equine Vet. J. pmid:8542848
Ducloux D et al. [Pseudo-cholangitis, a form of erythromycin-induced hepatitis]. 1995 Presse Med pmid:8545387
Brown GR Erythromycin-induced hypotension. 1995 Ann Pharmacother pmid:8547744
Stein CM et al. Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. 1996 Clin. Pharmacol. Ther. pmid:8549033
Bojar RA et al. Direct analysis of resistance in the cutaneous microflora during treatment of acne vulgaris with topical 1% nadifloxacin and 2% erythromycin. 1995 Drugs pmid:8549289
Morrissey I and Smith JT Activity of new 4-quinolones in combination with erythromycin or tetracycline against S. pneumoniae. 1995 Drugs pmid:8549311
Saito A and Gaja M In vitro and in vivo activities of sparfloxacin in Legionella infections. 1995 Drugs pmid:8549320
Fujimura M et al. Additive effect of continuous low dose ofloxacin on erythromycin therapy for sinobronchial syndrome. 1995 Drugs pmid:8549380
Kawahara S et al. Inhibitory effect of ofloxacin on acute exacerbations of chronic respiratory tract infections in comparison with erythromycin. 1995 Drugs pmid:8549382
Fujii T et al. Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection. 1995 Thorax pmid:8553295
Tateishi T et al. Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test. 1995 Br J Clin Pharmacol pmid:8554946
Tauch A et al. The Corynebacterium xerosis composite transposon Tn5432 consists of two identical insertion sequences, designated IS1249, flanking the erythromycin resistance gene ermCX. 1995 Plasmid pmid:8559800
Mitsuyama T et al. Inhibition by erythromycin of superoxide anion production by human polymorphonuclear leukocytes through the action of cyclic AMP-dependent protein kinase. 1995 Respiration pmid:8560094
Moriyama H et al. Evaluation of endoscopic sinus surgery for chronic sinusitis: post-operative erythromycin therapy. 1995 Rhinology pmid:8560171
Allen NE Macrolide resistance in Staphylococcus aureus: inducers of macrolide resistance. 1977 Antimicrob. Agents Chemother. pmid:856018
Arroyo J and Medoff G Mycobacterium chelonei infection: successful treatment based on a radiometric susceptibility test. 1977 Antimicrob. Agents Chemother. pmid:856032
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Martins C et al. Allergic contact dermatitis from erythromycin. 1995 Contact Derm. pmid:8565504
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Cherry JD Nosocomial pertussis in the nineties. 1995 Infect Control Hosp Epidemiol pmid:8568198
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Ishiura Y et al. Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome. 1995 Respir Med pmid:8570882
Roberts MC et al. Transferable erythromycin resistance in Listeria spp. isolated from food. 1996 Appl. Environ. Microbiol. pmid:8572704
Goswami BB et al. Physico-chemical properties and biological activities of erythromycin nalidixate. 1995 Arzneimittelforschung pmid:8573228
Lynch HC and Bushell ME The physiology of erythromycin biosynthesis in cyclic fed batch culture. 1995 Microbiology (Reading, Engl.) pmid:8574403
Kerr JR and Moore JE Potential for erythromycin resistance in porcine Campylobacter species. 1995 Trends Microbiol. pmid:8574518
Khair OA et al. Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells. 1995 Eur. Respir. J. pmid:8575568
Masclee AA et al. Effect of antrectomy and truncal vagotomy on erythromycin induced pancreatic polypeptide secretion. 1995 Regul. Pept. pmid:8577928
Slomiany BL et al. Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents. 1995 Scand. J. Gastroenterol. Suppl. pmid:8578215
Minocha A et al. Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. 1995 Aliment. Pharmacol. Ther. pmid:8580273
Tinanoff N et al. Dental treatment of Papillon-Lefèvre syndrome: 15-year follow-up. 1995 J. Clin. Periodontol. pmid:8583017
Bortolussi R et al. Clinical course of pertussis in immunized children. 1995 Pediatr. Infect. Dis. J. pmid:8584314
De Serres G et al. Field effectiveness of erythromycin prophylaxis to prevent pertussis within families. 1995 Pediatr. Infect. Dis. J. pmid:8584364
Hamzehpour MM et al. OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa. 1995 Antimicrob. Agents Chemother. pmid:8585714
Radulovic S et al. In vitro and in vivo antibiotic susceptibilities of ELB rickettsiae. 1995 Antimicrob. Agents Chemother. pmid:8585746
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Vasilos LV et al. [Chemotherapeutic effectiveness of erythromycin, rifampicin and tetracyclines in chlamydiosis and mycoplasmosis in children]. 1995 Antibiot. Khimioter. pmid:8593094
Schachter J and Dawson CR Is trachoma an ocular component of a more generalised chlamydial infection? 1979 Lancet pmid:85939
The choice of antibacterial drugs. 1996 Med Lett Drugs Ther pmid:8598824
Westh H Erythromycin-resistant Staphylococcus aureus in Denmark. 1996 APMIS Suppl. pmid:8600946
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Avila-Campos MJ et al. Distribution of biotypes and antimicrobial susceptibility of Actinobacillus actinomycetemcomitans. 1995 Oral Microbiol. Immunol. pmid:8602348
Oberg KC and Bauman JL QT interval prolongation and torsades de pointes due to erythromycin lactobionate. 1995 Nov-Dec Pharmacotherapy pmid:8602374
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Thompson D and Oster G Use of terfenadine and contraindicated drugs. 1996 JAMA pmid:8614120
Blumenfeld H et al. Trimethoprim and sulfonamide-associated meningoencephalitis with MRI correlates. 1996 Neurology pmid:8614533
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Hsueh PR et al. Decreased activity of erythromycin against Streptococcus pyogenes in Taiwan. 1995 Antimicrob. Agents Chemother. pmid:8619575
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Fang CC et al. Erythromycin-induced acute pancreatitis. 1996 J. Toxicol. Clin. Toxicol. pmid:8632521
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Gerber MA Antibiotic resistance: relationship to persistence of group A streptococci in the upper respiratory tract. 1996 Pediatrics pmid:8637784
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Yasui N et al. A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism. 1996 Clin. Pharmacol. Ther. pmid:8646822
Dam M et al. Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance. 1996 J. Mol. Biol. pmid:8648637
Vickery CL et al. Bacillary angiomatosis presenting as a nasal mass with epistaxis. 1996 Otolaryngol Head Neck Surg pmid:8649879
Pieper R et al. Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates. 1996 Biochemistry pmid:8652546
Mashkilleyson AL et al. Treatment of syphilis with azithromycin. 1996 Int J STD AIDS pmid:8652720