erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Critical Illness D016638 13 associated lipids
Bursitis D002062 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Acute Lung Injury D055371 33 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Rosacea D012393 13 associated lipids
Pericarditis D010493 6 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Heart Block D006327 3 associated lipids
Long QT Syndrome D008133 10 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Gonorrhea D006069 7 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Endometritis D004716 6 associated lipids
Vibrio Infections D014735 5 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Radiodermatitis D011855 3 associated lipids
Constipation D003248 8 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Varicose Ulcer D014647 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Pityriasis D010915 3 associated lipids
Xerostomia D014987 6 associated lipids
Hand Dermatoses D006229 5 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Ergotism D004881 4 associated lipids
Liver Abscess D008100 6 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Torsades de Pointes D016171 2 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Splenomegaly D013163 4 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Endocarditis D004696 4 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Gastroparesis D018589 2 associated lipids
Dyspepsia D004415 5 associated lipids
Asthenia D001247 5 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Tooth Diseases D014076 2 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Tourette Syndrome D005879 3 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Peptic Ulcer Hemorrhage D010438 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Bronchiectasis D001987 7 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Parotitis D010309 4 associated lipids
Dysarthria D004401 2 associated lipids
Lyme Disease D008193 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Bile Reflux D001655 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Animal Diseases D000820 2 associated lipids
Legionellosis D007876 3 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Blepharitis D001762 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Toothache D014098 3 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Pleuropneumonia D011001 3 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Intestinal Atresia D007409 3 associated lipids
Foot Ulcer D016523 4 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Balanitis D001446 4 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Jones TR et al. Efficacy of an antibiotic mouthwash in contaminated head and neck surgery. 1989 Am. J. Surg. pmid:2802036
Brass C et al. The effect of metronidazole on the incidence of postoperative wound infection in elective colon surgery. 1978 Am. J. Surg. pmid:341733
LeVeen HH et al. Effects of prophylactic antibiotics on colonic healing. 1976 Am. J. Surg. pmid:1247153
Carlson RG et al. Erythromycin enhances delayed gastric emptying in dogs after Roux-Y antrectomy. 1991 Am. J. Surg. pmid:1987856
Nissan A et al. Direct inhibitory effect of erythromycin on human alimentary tract smooth muscle. 2002 Am. J. Surg. pmid:11975929
Dillon ML and Bowling KA Effect of antibiotics on wound and stool cultures. Comparison of intravenous terramycin with other antibiotics. 1967 Am. J. Surg. pmid:5334435
Nakabayashi T et al. Gastropyloric motor activity and the effects of erythromycin given orally after esophagectomy. 2002 Am. J. Surg. pmid:11943134
COHN I and LONGACRE AB Erythromycin and erythromycin-neomycin for intestinal antisepsis. 1957 Am. J. Surg. pmid:13458603
Tzovaras G et al. The effect of intravenous erythromycin on esophageal motility in healthy subjects. 1996 Am. J. Surg. pmid:8615464
Gombert ME et al. Cavitary Legionnaires' pneumonia: nosocomial infection in renal transplant recipients. 1984 Am. J. Surg. pmid:6367506
Marshall W et al. Legionnaires' disease in renal transplant patients. 1981 Am. J. Surg. pmid:7013509
Pennathur A et al. Erythromycin strengthens the defective lower esophageal sphincter in patients with gastroesophageal reflux disease. 1994 Am. J. Surg. pmid:8311129
Fry DE Colon preparation and surgical site infection. 2011 Am. J. Surg. pmid:21429471
Weaver M et al. Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery. 1986 Am. J. Surg. pmid:3083705
Baciewicz AM and Baciewicz FA Cyclosporine pharmacokinetic drug interactions. 1989 Am. J. Surg. pmid:2644865
EICHENWALD HF and SHINEFIELD HR RATIONAL USE OF ANTIBIOTICS. 1964 Am. J. Surg. pmid:14129331
Condon RE et al. Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery. 1986 Am. J. Surg. pmid:3777340
Vanaudenaerde BM et al. Macrolides inhibit IL17-induced IL8 and 8-isoprostane release from human airway smooth muscle cells. 2007 Am. J. Transplant. pmid:17061983
JUNG RC et al. Fumagillin and erythromycin in the treatment of amebiasis. 1955 Am. J. Trop. Med. Hyg. pmid:13268803
MCHARDY G et al. Erythromycin in amebiasis. 1955 Am. J. Trop. Med. Hyg. pmid:13268804
NELSON TL et al. Amebic hepatitis; laboratory findings and treatment with erythromycin. 1955 Am. J. Trop. Med. Hyg. pmid:13259005
Hamel MJ et al. Efficacy of trimethoprim-sulfamethoxazole compared with sulfadoxine-pyrimethamine plus erythromycin for the treatment of uncomplicated malaria in children with integrated management of childhood illness dual classifications of malaria and pneumonia. 2005 Am. J. Trop. Med. Hyg. pmid:16172491
NOR EL-DIN G Erythromycin in the treatment of amebiasis. 1956 Am. J. Trop. Med. Hyg. pmid:13292653
Gingras BA and Jensen JB Activity of azithromycin (CP-62,993) and erythromycin against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro. 1992 Am. J. Trop. Med. Hyg. pmid:1326232
Robins-Browne RM et al. Treatment of acute nonspecific gastroenteritis of infants and young children with erythromycin. 1983 Am. J. Trop. Med. Hyg. pmid:6349401
WILMOT AJ et al. Erythromycin in amebic liver abscess. 1958 Am. J. Trop. Med. Hyg. pmid:13595213
ANDERSON HH et al. Erythromycin stearate against systemic amebiasis in Colombia. 1955 Am. J. Trop. Med. Hyg. pmid:13238724
VILLAREJOS VM Treatment of amebiasis with erythromycin. 1955 Am. J. Trop. Med. Hyg. pmid:13238725
Kelly DJ et al. Rickettsia tsutsugamushi infection in cell culture: antibiotic susceptibility determined by flow cytometry. 1995 Am. J. Trop. Med. Hyg. pmid:8561261
ANDERSON HH et al. Antibiotic synergism in amebiasis. 1954 Am. J. Trop. Med. Hyg. pmid:13138827
Hall KA et al. Characterization of counterfeit artesunate antimalarial tablets from southeast Asia. 2006 Am. J. Trop. Med. Hyg. pmid:17123969
Gingras BA and Jensen JB Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. 1993 Am. J. Trop. Med. Hyg. pmid:8394660
MCCOWEN MC et al. The effects of erythromycin (ilotycin, lilly) against certain parasitic organisms. 1953 Am. J. Trop. Med. Hyg. pmid:13040654
Crawford KA et al. Efficacy of amoscanate against experimental schistosomal infections in monkeys. 1983 Am. J. Trop. Med. Hyg. pmid:6625061
Perine PL and Teklu B Antibiotic treatment of louse-borne relapsing fever in Ethiopia: a report of 377 cases. 1983 Am. J. Trop. Med. Hyg. pmid:6625065
Lakritz J et al. Effect of treatment with erythromycin on bronchoalveolar lavage fluid cell populations in foals. 1997 Am. J. Vet. Res. pmid:8989497
MARSHALL RT et al. THE EFFECTS OF BLOOD AND NONFAT MILK CONSTITUTENTS ON DIFFUSION OF BACTERIAL INHIBITORS IN AGAR MEDIUMS. 1964 Am. J. Vet. Res. pmid:14266843
Garner HE and Coles EH Staphylococcus aureus of canine origin: bacteriophage typing and antibiotic sensitivity of cultures isolated from the nostril. 1965 Am. J. Vet. Res. pmid:5882553
Lester GD et al. Effect of erythromycin lactobionate on myoelectric activity of ileum, cecum, and right ventral colon, and cecal emptying of radiolabeled markers in clinically normal ponies. 1998 Am. J. Vet. Res. pmid:9522953
Nieto JE et al. Use of an extracorporeal circuit to evaluate effects of intraluminal distention and decompression on the equine jejunum. 2002 Am. J. Vet. Res. pmid:11843129
Palmer JE and Benson CE Effect of treatment with erythromycin and rifampin during the acute stages of experimentally induced equine ehrlichial colitis in ponies. 1992 Am. J. Vet. Res. pmid:1466503
Lakritz J et al. Pharmacokinetics of erythromycin estolate and erythromycin phosphate after intragastric administration to healthy foals. 2000 Am. J. Vet. Res. pmid:10951982
Lakritz J et al. Effects of prior feeding on pharmacokinetics and estimated bioavailability after oral administration of a single dose of microencapsulated erythromycin base in healthy foals. 2000 Am. J. Vet. Res. pmid:10976728
Khan SA et al. Characterization of erythromycin-resistant methylase genes from multiple antibiotic resistant Staphylococcus spp isolated from milk samples of lactating cows. 2000 Am. J. Vet. Res. pmid:10976747
Koenig JB et al. Use of multichannel electrointestinography for noninvasive assessment of myoelectrical activity in the cecum and large colon of horses. 2008 Am. J. Vet. Res. pmid:18518649
Afshari GR et al. Effect of parenteral administration of ivermectin and erythromycin on abomasal emptying rate in suckling calves. 2009 Am. J. Vet. Res. pmid:19335110
Koenig JB et al. Effect of intraluminal distension or ischemic strangulation obstruction of the equine jejunum on jejunal motilin receptors and binding of erythromycin lactobionate. 2006 Am. J. Vet. Res. pmid:16649915
DeGeeter MJ and Stahl GL Sensitivity of Escherichia coli after exposure to lincomycin in vitro and in vivo. 1976 Am. J. Vet. Res. pmid:776050
Burrows GE et al. Serum and tissue concentrations of erythromycin in calves with induced pneumonic pasteurellosis. 1989 Am. J. Vet. Res. pmid:2774339
Smith JA et al. Inhibitory and lethal activities of rosaramicin, erythromycin, and clindamycin against Campylobacter fetus subsp jejuni and intestinalis. 1983 Am. J. Vet. Res. pmid:6625312