erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Moncrieffe MC et al. | Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII. | 2012 | J. Mol. Biol. | pmid:22056329 |
Shimada M et al. | Corneal ulcer associated with pepper spray exposure during military training. | 2012 | J Emerg Med | pmid:22100497 |
Chouchani C et al. | First report of mefA and msrA/msrB multidrug efflux pumps associated with blaTEM-1 β-lactamase in Enterococcus faecalis. | 2012 | Int. J. Infect. Dis. | pmid:22137270 |
Ducrotté P and Gourcerol G | [Gastroparesis: pathophysiology and management]. | 2012 | Presse Med | pmid:22154929 |
Back EE et al. | High rates of perinatal group B Streptococcus clindamycin and erythromycin resistance in an upstate New York hospital. | 2012 | Antimicrob. Agents Chemother. | pmid:22143529 |
Boswihi SS et al. | Serotypes and antibiotic resistance in Group B streptococcus isolated from patients at the Maternity Hospital, Kuwait. | 2012 | J. Med. Microbiol. | pmid:21903822 |
Jada S et al. | Design and synthesis of novel magnolol derivatives as potential antimicrobial and antiproliferative compounds. | 2012 | Eur J Med Chem | pmid:22424614 |
Saxena S et al. | Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus at a tertiary care hospital: implications for clinical therapy. | 2012 | J Commun Dis | pmid:25151754 |
Bai J et al. | Erythromycin enhances CD4+Foxp3+ regulatory T-cell responses in a rat model of smoke-induced lung inflammation. | 2012 | Mediators Inflamm. | pmid:22701274 |
Vázquez-Sánchez D et al. | Incidence and characterization of Staphylococcus aureus in fishery products marketed in Galicia (Northwest Spain). | 2012 | Int. J. Food Microbiol. | pmid:22704064 |
Correa AM et al. | [Pneumococcal bacteremia in adult patients at a hospital in Madrid: serotypes and susceptibility]. | 2012 | Rev Esp Quimioter | pmid:22707105 |
Teodoro CR et al. | Characterization of MLS(b) resistance among Staphylococcus aureus and Staphylococcus epidermidis isolates carrying different SCCmec types. | 2012 | Microbiol. Immunol. | pmid:22672011 |
Hossein nia R et al. | An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22892120 |
Ishibashi K et al. | Usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery. | 2012 | Asian J Surg | pmid:22720863 |
Chiba Y et al. | Mechanism for folate-independent aldolase reaction catalyzed by serine hydroxymethyltransferase. | 2012 | FEBS J. | pmid:22141341 |
Nelson CG and Burke TR | Samarium iodide-mediated Reformatsky reactions for the stereoselective preparation of β-hydroxy-γ-amino acids: synthesis of isostatine and dolaisoleucine. | 2012 | J. Org. Chem. | pmid:22136325 |
Zhou X et al. | Marthiapeptide A, an anti-infective and cytotoxic polythiazole cyclopeptide from a 60 L scale fermentation of the deep sea-derived Marinactinospora thermotolerans SCSIO 00652. | 2012 | J. Nat. Prod. | pmid:23215246 |
Milberg P et al. | Blockade of I(Ca) suppresses early afterdepolarizations and reduces transmural dispersion of repolarization in a whole heart model of chronic heart failure. | 2012 | Br. J. Pharmacol. | pmid:22013922 |
Benet LZ | A step closer to personalized chemotherapy: consideration of the influence of genetic variation in hepatic uptake transporters on the metabolism of CYP3A substrates. | 2012 | Clin. Pharmacol. Ther. | pmid:23085879 |
Zhou Q et al. | SigB-dependent tolerance to protein synthesis-inhibiting antibiotics in Listeria monocytogenes EGDe. | 2012 | Curr. Microbiol. | pmid:22143398 |
Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
Ezhova NM et al. | [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. | 2011 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:22288199 |
Zhang L et al. | Synthesis and antibacterial activity of new 4″-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether. | 2011 | J. Antibiot. | pmid:21245870 |
Nielsen EI et al. | Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. | 2011 | Antimicrob. Agents Chemother. | pmid:21282424 |
Belousoff MJ et al. | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21282615 |
Spigaglia P et al. | Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. | 2011 | Emerging Infect. Dis. | pmid:21291621 |
Watanabe I et al. | Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block. | 2011 | Int Heart J | pmid:22188715 |
Jessick AM et al. | Optimization of analytical methods to improve detection of erythromycin from water and sediment. | 2011 | J Environ Sci Health B | pmid:21877980 |
Lee CY et al. | Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. | 2011 | Implant Dent | pmid:21881516 |
Tazi A et al. | Invasive group B streptococcal infections in adults, France (2007-2010). | 2011 | Clin. Microbiol. Infect. | pmid:21883671 |
Sugiyama E et al. | The use of 13C-erythromycin as an in vivo probe to evaluate CYP3A-mediated drug interactions in rats. | 2011 | J Pharm Sci | pmid:21618542 |
Fenoll A et al. | Increase in serotype 19A prevalence and amoxicillin non-susceptibility among paediatric Streptococcus pneumoniae isolates from middle ear fluid in a passive laboratory-based surveillance in Spain, 1997-2009. | 2011 | BMC Infect. Dis. | pmid:21910891 |
Qin X et al. | Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. | 2011 | Int. J. Antimicrob. Agents | pmid:21549571 |
Maezono H et al. | Antibiofilm effects of azithromycin and erythromycin on Porphyromonas gingivalis. | 2011 | Antimicrob. Agents Chemother. | pmid:21911560 |
Sigaroudinia MO and Quayle AR | Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. | 2011 | Surgeon | pmid:21550524 |
You L et al. | Dynamic multi-component covalent assembly for the reversible binding of secondary alcohols and chirality sensing. | 2011 | Nat Chem | pmid:22109274 |
Wingard JB et al. | A novel cell-associated protection assay demonstrates the ability of certain antibiotics to protect ocular surface cell lines from subsequent clinical Staphylococcus aureus challenge. | 2011 | Antimicrob. Agents Chemother. | pmid:21628536 |
Amachawadi RG et al. | Selection of fecal enterococci exhibiting tcrB-mediated copper resistance in pigs fed diets supplemented with copper. | 2011 | Appl. Environ. Microbiol. | pmid:21705534 |
Tanamachi C et al. | [A case of Desulfovibrio desulfuricans cultured from blood in Japan]. | 2011 | Rinsho Byori | pmid:21706860 |
Mikura S et al. | Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. | 2011 | Transl Res | pmid:21708354 |
Richter SS et al. | Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. | 2011 | Antimicrob. Agents Chemother. | pmid:21709080 |
Panigaj M et al. | Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. | 2011 | PLoS ONE | pmid:21912705 |
Buendia J et al. | Preparation of diastereomerically pure dilignol model compounds. | 2011 | Chemistry | pmid:22076640 |
Maragno AL et al. | ISG15 modulates development of the erythroid lineage. | 2011 | PLoS ONE | pmid:22022510 |
Kreft A et al. | JAK2-V617F-mutated myeloproliferative neoplasms reveal different allele burden within hematopoietic cell lineages: a microdissection study of bone marrow trephine biopsies. | 2011 | Virchows Arch. | pmid:22006129 |
Pignatello R et al. | Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. | 2011 | AAPS PharmSciTech | pmid:21479751 |
Keelan JA et al. | Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. | 2011 | Am. J. Obstet. Gynecol. | pmid:21481833 |
Fan C and He J | Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. | 2011 | Water Res. | pmid:21482429 |
Ho PL et al. | Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:22000087 |
Li Y et al. | Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. | 2011 | J. Appl. Microbiol. | pmid:20961364 |