erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Critical Illness D016638 13 associated lipids
Bursitis D002062 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Acute Lung Injury D055371 33 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Rosacea D012393 13 associated lipids
Pericarditis D010493 6 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Heart Block D006327 3 associated lipids
Long QT Syndrome D008133 10 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Gonorrhea D006069 7 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Endometritis D004716 6 associated lipids
Vibrio Infections D014735 5 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Radiodermatitis D011855 3 associated lipids
Constipation D003248 8 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Varicose Ulcer D014647 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Pityriasis D010915 3 associated lipids
Xerostomia D014987 6 associated lipids
Hand Dermatoses D006229 5 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Ergotism D004881 4 associated lipids
Liver Abscess D008100 6 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Torsades de Pointes D016171 2 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Splenomegaly D013163 4 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Endocarditis D004696 4 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Gastroparesis D018589 2 associated lipids
Dyspepsia D004415 5 associated lipids
Asthenia D001247 5 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Tooth Diseases D014076 2 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Tourette Syndrome D005879 3 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Peptic Ulcer Hemorrhage D010438 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Bronchiectasis D001987 7 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Parotitis D010309 4 associated lipids
Dysarthria D004401 2 associated lipids
Lyme Disease D008193 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Bile Reflux D001655 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Animal Diseases D000820 2 associated lipids
Legionellosis D007876 3 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Blepharitis D001762 4 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Toothache D014098 3 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Pleuropneumonia D011001 3 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Intestinal Atresia D007409 3 associated lipids
Foot Ulcer D016523 4 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Balanitis D001446 4 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Zhang W et al. Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. 2011 Curr. Microbiol. pmid:20924584
Hewer RC et al. PKA and Epac synergistically inhibit smooth muscle cell proliferation. 2011 J. Mol. Cell. Cardiol. pmid:20971121
Fessler AT et al. Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. 2011 Antimicrob. Agents Chemother. pmid:20876371
Nakashima R et al. Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. 2011 Nature pmid:22121023
Abarzúa F et al. [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. 2011 Rev Chilena Infectol pmid:22052397
Song W et al. Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. 2011 Int J Nanomedicine pmid:22228990
Hiller NL et al. Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. 2011 PLoS ONE pmid:22205975
Tachecí I et al. Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. 2011 Neuro Endocrinol. Lett. pmid:22167215
Lam HS and Ng PC Use of prokinetics in the preterm infant. 2011 Curr. Opin. Pediatr. pmid:21178622
Ma S et al. Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. 2011 Eur J Med Chem pmid:21159410
Mak PJ et al. Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. 2011 J. Am. Chem. Soc. pmid:21207936
Ren GW et al. Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. 2011 Foodborne Pathog. Dis. pmid:21166562
Srinivasan U et al. Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae. 2011 Microb. Drug Resist. pmid:21166574
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Wunder DB et al. Sorption of antibiotics to biofilm. 2011 Water Res. pmid:21334040
Sonnevend Á et al. Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. 2011 Scand. J. Infect. Dis. pmid:21905953
Wei Z and Wang J Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. 2011 Anal. Chim. Acta pmid:21565301
Ren W and Markel DC Emerging ideas: can erythromycin reduce the risk of aseptic loosening? 2011 Clin. Orthop. Relat. Res. pmid:21584820
Torra S et al. Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). 2011 Int J Obes (Lond) pmid:20938444
Li MJ et al. High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. 2011 Analyst pmid:20944848
Li AP and Doshi U Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. 2011 Drug Metab Lett pmid:21722087
Imperi M et al. Invasive neonatal GBS infections from an area-based surveillance study in Italy. 2011 Clin. Microbiol. Infect. pmid:21722258
Wan G et al. Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. 2011 Cell. Signal. pmid:21723942
Miyashita N et al. Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. 2011 J. Infect. Chemother. pmid:20676912
Chen I et al. Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. 2011 J. Clin. Microbiol. pmid:21068284
Bilk S et al. Antimicrobial susceptibilities and occurrence of resistance genes in bovine Helcococcus ovis isolates. 2011 Vet. Microbiol. pmid:21131144
Zou X et al. An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. 2011 Bioresour. Technol. pmid:21134745
Modali SD and Zgurskaya HI The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. 2011 Mol. Microbiol. pmid:21696464
Jorgensen JH et al. Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. 2011 J. Clin. Microbiol. pmid:21697321
Wenzel F et al. Alterations of serum erythropoietin and thrombopoietin levels in patients undergoing Coronary Artery Bypass Grafting (CABG). 2011 Clin. Hemorheol. Microcirc. pmid:22214710
Mansi Y et al. Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants. 2011 Neonatology pmid:21701222
Amarir-Bouhram J et al. Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. 2011 PLoS ONE pmid:22194937
Ng PC Erythromycin as a prokinetic agent in newborns--useful or doubtful. Commentary on Y. Mansi et al.: Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants (Neonatology 2011;100:290-294). 2011 Neonatology pmid:21701224
Sarig H et al. Functional studies of cochleate assemblies of an oligo-acyl-lysyl with lipid mixtures for combating bacterial multidrug resistance. 2011 FASEB J. pmid:21676947
Shingate BB et al. Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. 2011 Eur J Med Chem pmid:21664730
Hoa PT et al. Antibiotic contamination and occurrence of antibiotic-resistant bacteria in aquatic environments of northern Vietnam. 2011 Sci. Total Environ. pmid:21669325
Boghigian BA et al. Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. 2011 Biotechnol. Bioeng. pmid:21337322
Kataoka M et al. Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. 2011 Eur J Pharm Sci pmid:21963456
Hernández y Ballinas A et al. [Comparison of maternal and perinatal outcomes in the conservative treatment preterm premature membrane rupture between the use of erythromycin and clindamycin]. 2011 Ginecol Obstet Mex pmid:21966834
Gupta R et al. A 14-year-old with rectal bleeding and abdominal pain. 2011 J. Pediatr. Gastroenterol. Nutr. pmid:21970991
Heath AP et al. An algorithm for efficient identification of branched metabolic pathways. 2011 J. Comput. Biol. pmid:21999288
Ho PL et al. Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. 2011 Diagn. Microbiol. Infect. Dis. pmid:22000087
Boleda MA et al. Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments. 2011 Environ. Pollut. pmid:21459501
Zhang Z et al. Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21498135
Del Grosso M et al. Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. 2011 Antimicrob. Agents Chemother. pmid:21502613
Loreto ES et al. In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. 2011 Antimicrob. Agents Chemother. pmid:21537028
Nakamura PA et al. Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. 2011 Mem. Inst. Oswaldo Cruz pmid:21537668
Shaala LA et al. Brominated arginine-derived alkaloids from the red sea sponge Suberea mollis. 2011 J. Nat. Prod. pmid:21542602
Chen HX et al. [Compound erythromycin sustained release preparation and its in vitro release]. 2011 Yao Xue Xue Bao pmid:22260035
Wei Z et al. [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. 2011 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22260078