erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Namikawa H et al. | Effect of erythromycin A and its new derivative EM201 on type I collagen production by cultured dermal fibroblasts. | 2010 | Arch. Dermatol. Res. | pmid:19578864 |
Dhamdhere G et al. | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. | 2010 | Antimicrob. Agents Chemother. | pmid:20876376 |
He ZY et al. | Effect of 6 months of erythromycin treatment on inflammatory cells in induced sputum and exacerbations in chronic obstructive pulmonary disease. | 2010 | Respiration | pmid:20881376 |
Liu Y et al. | 9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. | 2010 | Bioorg. Med. Chem. | pmid:20869254 |
Leszczyńska K et al. | Modulation of exogenous antibiotic activity by host cathelicidin LL-37. | 2010 | APMIS | pmid:20955455 |
Atkins JL et al. | Enhancement of antimicrobial activity by synthetic ion channel synergy. | 2010 | Chem. Commun. (Camb.) | pmid:20931142 |
van der Beek MT et al. | Inaccuracy of routine susceptibility tests for detection of erythromycin resistance of Campylobacter jejuni and Campylobacter coli. | 2010 | Clin. Microbiol. Infect. | pmid:19438640 |
Aguilera R C et al. | [Antimicrobial susceptibility, capsular serotypes and clonal relationship of invasive streptococcus pneumoniae isolates in adult population of the Bio-Bio region, Chile. 2005-2006]. | 2010 | Rev Chilena Infectol | pmid:21186502 |
Fomda BA et al. | Phenotypic detection of constitutive and inducible clindamycin resistance in clinical isolates of Staphylococcus aureus and coagulase negative Staphylococcus on routine susceptibility plate. | 2010 | J Commun Dis | pmid:22468547 |
Pazoki-Toroudi H et al. | Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. | 2010 | J Dermatolog Treat | pmid:20394495 |
Florindo C et al. | Molecular characterization and antimicrobial susceptibility profiles in Streptococcus agalactiae colonizing strains: association of erythromycin resistance with subtype III-1 genetic clone family. | 2010 | Clin. Microbiol. Infect. | pmid:19886900 |
Ohlsson B et al. | Antibodies against gonadotropin-releasing hormone (GnRH) and destruction of enteric neurons in 3 patients suffering from gastrointestinal dysfunction. | 2010 | BMC Gastroenterol | pmid:20487533 |
Chandra B et al. | Catalytic asymmetric synthesis of complex polypropionates: Lewis base catalyzed aldol equivalents in the synthesis of erythronolide B. | 2010 | Angew. Chem. Int. Ed. Engl. | pmid:20209542 |
Chen B et al. | Study on enantiomeric separation of basic drugs by NACE in methanol-based medium using erythromycin lactobionate as a chiral selector. | 2010 | Electrophoresis | pmid:20024923 |
Yao J et al. | Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. | 2010 | Bioorg. Med. Chem. Lett. | pmid:19959361 |
Tokuda A et al. | Effects of macrolides on antigen-induced increases in cough reflex sensitivity in guinea pigs. | 2010 | Pulm Pharmacol Ther | pmid:19835975 |
Padilla E et al. | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. | 2010 | Antimicrob. Agents Chemother. | pmid:19858254 |
Goetting-Minesky MP and Fenno JC | A simplified erythromycin resistance cassette for Treponema denticola mutagenesis. | 2010 | J. Microbiol. Methods | pmid:20691222 |
Mazzoncini JP et al. | Human metapneumovirus: an emerging respiratory pathogen. | 2010 | J Emerg Med | pmid:18584996 |
Banche G et al. | Synergistic effect of erythromycin on polymorphonuclear cell antibacterial activity against erythromycin-resistant phenotypes of Streptococcus pyogenes. | 2010 | Int. J. Antimicrob. Agents | pmid:20692129 |
Bourne CR et al. | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. | 2010 | Antimicrob. Agents Chemother. | pmid:20606069 |
Bohnert JA et al. | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. | 2010 | Antimicrob. Agents Chemother. | pmid:20606071 |
Horner P | Chlamydia (uncomplicated, genital). | 2010 | BMJ Clin Evid | pmid:21718568 |
Ren W et al. | Efficacy of periprosthetic erythromycin delivery for wear debris-induced inflammation and osteolysis. | 2010 | Inflamm. Res. | pmid:20607583 |
Ortiz-Pérez A et al. | High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species. | 2010 | Microb. Drug Resist. | pmid:20624090 |
Dundar D et al. | Macrolide and tetracycline resistance and emm type distribution of Streptococcus pyogenes isolates recovered from Turkish patients. | 2010 | Microb. Drug Resist. | pmid:20624096 |
Elmorsy S et al. | Sinus aspirates in chronic rhinosinusitis: fungal colonization of paranasal sinuses, evaluation of ICAM-1 and IL-8 and studying of immunological effect of long-term macrolide therapy. | 2010 | Rhinology | pmid:21038022 |
Zhang H et al. | Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli. | 2010 | Biotechnol. Bioeng. | pmid:19806677 |
Wu J et al. | Construction and performance of heterologous polyketide-producing K-12- and B-derived Escherichia coli. | 2010 | Lett. Appl. Microbiol. | pmid:20565574 |
Harris JB et al. | Cholera's western front. | 2010 | Lancet | pmid:21112083 |
Cane DE | Programming of erythromycin biosynthesis by a modular polyketide synthase. | 2010 | J. Biol. Chem. | pmid:20522551 |
Zou S et al. | Isolation, identification of Streptococcus pneumoniae from infected rhesus monkeys and control efficacy. | 2010 | J. Med. Primatol. | pmid:20524954 |
Kwatra D et al. | Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance. | 2010 | Int J Pharm | pmid:20573570 |
Ying L and Tang D | Recent advances in the medicinal chemistry of novel erythromycin-derivatized antibiotics. | 2010 | Curr Top Med Chem | pmid:20536419 |
Fernandes NF et al. | Pityriasis lichenoides et varioliformis acuta: a disease spectrum. | 2010 | Int. J. Dermatol. | pmid:20465660 |
El-Mahdy TS et al. | Detection of a new erm(X)-mediated antibiotic resistance in Egyptian cutaneous propionibacteria. | 2010 | Anaerobe | pmid:20541615 |
Kana BD et al. | Depletion of resuscitation-promoting factors has limited impact on the drug susceptibility of Mycobacterium tuberculosis. | 2010 | J. Antimicrob. Chemother. | pmid:20542905 |
Levêque D et al. | [Mechanisms of pharmacokinetic drug-drug interactions]. | 2010 | Rev Med Interne | pmid:19740579 |
Urakawa H et al. | Structure-activity relationships of bacterial outer-membrane permeabilizers based on polymyxin B heptapeptides. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20138759 |
Roger PM et al. | [Urinary pneumococcal or Legionella antigen detection tests and low-spectrum antibiotic therapy for community-acquired pneumonia]. | 2010 | Med Mal Infect | pmid:20172672 |
Woosley LN et al. | CEM-101 activity against Gram-positive organisms. | 2010 | Antimicrob. Agents Chemother. | pmid:20176910 |
Mulhbacher J et al. | Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways. | 2010 | PLoS Pathog. | pmid:20421948 |
Morrow BJ et al. | In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone. | 2010 | Antimicrob. Agents Chemother. | pmid:20176911 |
Fraser RJ and Bryant L | Current and future therapeutic prokinetic therapy to improve enteral feed intolerance in the ICU patient. | 2010 | Nutr Clin Pract | pmid:20130155 |
Cocco G and Gasparyan AY | Myocardial ischemia in Wegener's granulomatosis: coronary atherosclerosis versus vasculitis. | 2010 | Open Cardiovasc Med J | pmid:20360980 |
Auerbach T et al. | The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080686 |
Krenauer A et al. | EBV-associated post-transplantation B-cell lymphoproliferative disorder following allogenic stem cell transplantation for acute lymphoblastic leukaemia: tumor regression after reduction of immunosuppression--a case report. | 2010 | Diagn Pathol | pmid:20356360 |
Prakash H et al. | Sphingosine kinase-1 (SphK-1) regulates Mycobacterium smegmatis infection in macrophages. | 2010 | PLoS ONE | pmid:20498849 |
Sakahara S et al. | Physiological characteristics of gastric contractions and circadian gastric motility in the free-moving conscious house musk shrew (Suncus murinus). | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20686171 |
Di Luca MC et al. | Lysogenic transfer of mef(A) and tet(O) genes carried by Phim46.1 among group A streptococci. | 2010 | Antimicrob. Agents Chemother. | pmid:20643900 |