erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tarsi R and Vitali C | [Erythromycin: serum and urine levels following rectal administration (author's transl)]. | 1976 Jul-Aug | Ann Sclavo | pmid:1020971 |
| Burstin PP and Marshall CL | Infectious mononucleosis and bilateral peritonsillar abscesses resulting in airway obstruction. | 1998 | J Laryngol Otol | pmid:10209619 |
| Imshenetskaia VF | [Erythromycin penetration into the cerebrospinal fluid of patients]. | 1976 | Antibiotiki | pmid:1020930 |
| Mishra A et al. | The effects of erythromycin on the electrocardiogram. | 1999 | Chest | pmid:10208196 |
| Vyhnálek J | [Distribution of erythromycin following intramuscular administration in laboratory animals]. | 1978 | Vet Med (Praha) | pmid:102070 |
| Vermeulen B et al. | The formulation and stability of erythromycin-benzoyl peroxide in a topical gel. | 1999 | Int J Pharm | pmid:10205634 |
| Sefton AM | Macrolides and changes in the oral flora. | 1999 | Int. J. Antimicrob. Agents | pmid:10204636 |
| MiliavskiÄ AI and Kostenko AM | [Early prevention of syphilis (experimental study)]. | 1976 | Vestn Dermatol Venerol | pmid:1020461 |
| Vasil'ev TV et al. | [Immediate results of treatment of syphilis with erythromycin simultaneously with bismuth preparations]. | 1976 | Vestn Dermatol Venerol | pmid:1020453 |
| Hall JA and Washabau RJ | Diagnosis and treatment of gastric motility disorders. | 1999 | Vet. Clin. North Am. Small Anim. Pract. | pmid:10202795 |
| Scarpignato C and Pelosini I | Management of irritable bowel syndrome: novel approaches to the pharmacology of gut motility. | 1999 | Can. J. Gastroenterol. | pmid:10202210 |
| Jarrett F et al. | Antibiotic bowel preparation and burn wound colonization. | 1976 | Surg Forum | pmid:1019996 |
| Sakaeva DD and Lazareva DN | [The effect of erythromycin on immunity in immunodeficiency]. | 1999 Jan-Feb | Eksp Klin Farmakol | pmid:10198768 |
| Montenez JP et al. | Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [Dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models. | 1999 | Toxicol. Appl. Pharmacol. | pmid:10198278 |
| Dorner S and Barta A | Probing ribosome structure by europium-induced RNA cleavage. | 1999 | Biol. Chem. | pmid:10195431 |
| Stenson BJ et al. | Influence of erythromycin on establishment of feeding in preterm infants: observations from a randomised controlled trial. | 1998 | Arch. Dis. Child. Fetal Neonatal Ed. | pmid:10194995 |
| Isohanni MH et al. | Effect of erythromycin and itraconazole on the pharmacokinetics of oral lignocaine. | 1999 | Pharmacol. Toxicol. | pmid:10193676 |
| Mthwalo M et al. | Antibiotic resistance of nasopharyngeal isolates of Streptococcus pneumoniae from children in Lesotho. | 1998 | Bull. World Health Organ. | pmid:10191560 |
| Kinirons MT et al. | Effects of ketoconazole on the erythromycin breath test and the dapsone recovery ratio. | 1999 | Br J Clin Pharmacol | pmid:10190659 |
| Karlsson M et al. | Genetic basis of macrolide and lincosamide resistance in Brachyspira (Serpulina) hyodysenteriae. | 1999 | FEMS Microbiol. Lett. | pmid:10188254 |