erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nieuwenhuijs VB et al. | The effects of ABT-229 and octreotide on interdigestive small bowel motility, bacterial overgrowth and bacterial translocation in rats. | 1999 | Eur. J. Clin. Invest. | pmid:10092986 |
| Sunazuka T et al. | Effects of erythromycin and its derivatives on interleukin-8 release by human bronchial epithelial cell line BEAS-2B cells. | 1999 | J. Antibiot. | pmid:10092202 |
| Stacey A and Bradlow A | Arcanobacterium haemolyticum and Mycoplasma pneumoniae co-infection. | 1999 | J. Infect. | pmid:10090506 |
| Suzuki H et al. | Inhibitory effect of erythromycin on interleukin-8 secretion from exudative cells in the nasal discharge of patients with chronic sinusitis. | 1999 | Laryngoscope | pmid:10089966 |
| Zweers-Zeilmaker WM et al. | In vitro complex formation and inhibition of hepatic cytochrome P450 activity by different macrolides and tiamulin in goats and cattle. | 1999 | Res. Vet. Sci. | pmid:10088712 |
| Nakata K | [Diffuse panbronchiolitis (DPB)]. | 1999 | Ryoikibetsu Shokogun Shirizu | pmid:10088434 |
| Sagara H | [Campylobacter enteritis]. | 1999 | Ryoikibetsu Shokogun Shirizu | pmid:10088324 |
| Iordănescu S | Three distinct plasmids originating in the same Staphylococcus aureus strain. | 1976 Jan-Jun | Arch Roum Pathol Exp Microbiol | pmid:1008685 |
| Clark MJ et al. | Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum. | 1999 | Clin. Exp. Pharmacol. Physiol. | pmid:10081621 |
| Horn S et al. | Cholestasis and liver cell damage due to hypersensitivity to erythromycin stearate--recurrence following therapy with erythromycin succinate. | 1999 | Wien. Klin. Wochenschr. | pmid:10081126 |
| DiBaise JK and Quigley EM | Efficacy of prolonged administration of intravenous erythromycin in an ambulatory setting as treatment of severe gastroparesis: one center's experience. | 1999 | J. Clin. Gastroenterol. | pmid:10078820 |
| Periti P and Mazzei T | Clarithromycin: pharmacokinetic and pharmacodynamic interrelationships and dosage regimen. | 1999 | J Chemother | pmid:10078776 |
| Collard JM et al. | Erythromycin enhances early postoperative contractility of the denervated whole stomach as an esophageal substitute. | 1999 | Ann. Surg. | pmid:10077045 |
| Cline MS et al. | Bacillary angiomatosis in a renal transplant recipient. | 1999 | Transplantation | pmid:10075597 |
| Hsueh PR et al. | Extremely high incidence of macrolide and trimethoprim-sulfamethoxazole resistance among clinical isolates of Streptococcus pneumoniae in Taiwan. | 1999 | J. Clin. Microbiol. | pmid:10074498 |
| Lu W et al. | [Analysis of 37 cases of pneumonia of Legionnaires' disease]. | 1997 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:10072832 |
| Manna PK and Basu SK | Studies of erythromycin maltobionate, a new derivative of erythromycin. | 1999 | Drug Dev Ind Pharm | pmid:10071836 |
| GarcÃa de Lomas J et al. | [Sensitivity of group A beta-hemolytic Streptococcus isolated from pediatric pharyngotonsillitis to erythromycin and clarithromycin: a primary care multicenter study]. | 1999 | Enferm. Infecc. Microbiol. Clin. | pmid:10069109 |
| Nielsen J | The role of metabolic engineering in the production of secondary metabolites. | 1998 | Curr. Opin. Microbiol. | pmid:10066494 |
| Dordick JS et al. | The evolution of biotransformation technologies. | 1998 | Curr. Opin. Microbiol. | pmid:10066492 |