erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Eisenberg VH et al. | Legionnaire's disease during pregnancy: a case presentation and review of the literature. | 1997 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:9076416 |
Pehl C et al. | Effect of erythromycin on postprandial gastroesophageal reflux in reflux esophagitis. | 1997 | Dis. Esophagus | pmid:9079271 |
Hoppe JE | [Whooping cough in pregnant patients and newborn infants]. | 1996 Nov-Dec | Z Geburtshilfe Neonatol | pmid:9081753 |
Walz A et al. | Excellent activity of newer quinolones on Legionella pneumophila in J774 macrophages. | 1997 | Zentralbl. Bakteriol. | pmid:9084116 |
al-Humayyd MS | Pharmacokinetic interactions between erythromycin, clarithromycin, roxithromycin and phenytoin in the rat. | 1997 Mar-Apr | Chemotherapy | pmid:9084915 |
Qadri SM et al. | In vitro activity of quinupristin/dalfopristin, RP59500, against gram-positive clinical isolates. | 1997 Mar-Apr | Chemotherapy | pmid:9084917 |
Traub WH and Leonhard B | Antibiotic susceptibility of alpha- and nonhemolytic streptococci from patients and healthy adults to 24 antimicrobial drugs. | 1997 Mar-Apr | Chemotherapy | pmid:9084921 |
Wu JJ et al. | High incidence of erythromycin-resistant streptococci in Taiwan. | 1997 | Antimicrob. Agents Chemother. | pmid:9087502 |
Konishi T and Nakao M | Antibiotic treatment in mice infected with Japanese Borrelia garinii: efficacy of ceftriaxone for eradicating the infection induced by Ixodes persulcatus tick bites. | 1997 | Microbiol. Immunol. | pmid:9087959 |
Costa A et al. | In vivo characterization of the colonic prokinetic effect of erythromycin in the rabbit. | 1997 | Pharmacology | pmid:9088039 |
Sato F et al. | EM574, an erythromycin derivative, is a motilin receptor agonist in the rabbit. | 1997 | Eur. J. Pharmacol. | pmid:9088872 |
Singh G et al. | An audit of the problems in management of patients with gonorrhoea. | 1997 | Int J STD AIDS | pmid:9089036 |
Lerman SJ | Prevention of rheumatic recurrence in the allergic, rheumatic fever patient. | 1977 | J. Pediatr. | pmid:909037 |
Wilson WR | Tetracyclines, chloramphenicol, erythromycin, and clindamycin. | 1977 | Mayo Clin. Proc. | pmid:909315 |
Midolo PD et al. | Bactericidal activity and synergy studies of proton pump inhibitors and antibiotics against Helicobacter pylori in vitro. | 1997 | J. Antimicrob. Chemother. | pmid:9096182 |
Göres E et al. | [Animal experimental studies on the improvement of rectal absorption of chloramphenicol]. | 1977 | Pharmazie | pmid:909908 |
Townsend GC and Mandell GL | The new antibiotics, 1997. | 1997 | Va Med Q | pmid:9100474 |
Mikasa K et al. | [Lung cancer: progress in diagnosis and treatment. IV. Related topics: 2. Macrolides as biological response modifiers for the treatment of lung cancer]. | 1997 | Nippon Naika Gakkai Zasshi | pmid:9102408 |
Kato A | [Effect of erythromycin and clarithromycin on ion transport across dissected canine tracheal epithelium]. | 1997 | Nippon Jibiinkoka Gakkai Kaiho | pmid:9103848 |
Fietta A et al. | Requirements for intracellular accumulation and release of clarithromycin and azithromycin by human phagocytes. | 1997 | J Chemother | pmid:9106014 |
Monji H et al. | Highly sensitive high-performance liquid chromatographic determination method for a new erythromycin derivative, EM523, and its major metabolites in human plasma and urine using post-column tris(2,2'-bipyridine) ruthenium(III) chemiluminescence detection. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9106057 |
Klein JO | History of macrolide use in pediatrics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109154 |
McCracken GH | Microbiologic activity of the newer macrolide antibiotics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109155 |
Tarlow MJ | Macrolides in the management of streptococcal pharyngitis/tonsillitis. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109157 |
Norinder A et al. | Economic analysis of treatment with roxithromycin in comparison with erythromycin in patients with lower respiratory tract infections. | 1997 | Scand. J. Infect. Dis. | pmid:9112304 |
Watanabe Y et al. | [Relationship between quality and serum level after the oral administration of commercial erythromycin tablets in man (author's transl)]. | 1977 | Yakugaku Zasshi | pmid:911413 |
Leach AJ et al. | A prospective study of the impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae. | 1997 | Clin. Infect. Dis. | pmid:9114185 |
Koley AP et al. | Differential interaction of erythromycin with cytochromes P450 3A1/2 in the endoplasmic reticulum: a CO flash photolysis study. | 1997 | Biochemistry | pmid:9116001 |
Samsom M et al. | Effects of oral erythromycin on fasting and postprandial antroduodenal motility in patients with type I diabetes, measured with an ambulatory manometric technique. | 1997 | Diabetes Care | pmid:9118759 |
Atorvastatin--a new lipid-lowering drug. | 1997 | Med Lett Drugs Ther | pmid:9121394 | |
Müller M et al. | Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans. | 1996 | Antimicrob. Agents Chemother. | pmid:9124826 |
Roord JJ et al. | Prospective open randomized study comparing efficacies and safeties of a 3-day course of azithromycin and a 10-day course of erythromycin in children with community-acquired acute lower respiratory tract infections. | 1996 | Antimicrob. Agents Chemother. | pmid:9124837 |
Muranaka H et al. | Superoxide scavenging activity of erythromycin-iron complex. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9125127 |
Langer JC and Bramlett G | Effect of prokinetic agents on ileal contractility in a rabbit model of gastroschisis. | 1997 | J. Pediatr. Surg. | pmid:9126764 |
Jones RN and Biedenbach DJ | Antimicrobial activity of RU-66647, a new ketolide. | 1997 Jan-Feb | Diagn. Microbiol. Infect. Dis. | pmid:9127099 |
Nakagawa A et al. | A search for Pseudomonas alginate biosynthesis inhibitors from microbial metabolites. | 1997 | J. Antibiot. | pmid:9127207 |
Furuya E | Removal of interference by erythromycin, phenazopyridine, and methenamine mandelate in the Porter-Silber reaction. | 1977 | Clin. Chem. | pmid:912880 |
van Holten J et al. | Neonatal Borrelia duttoni infection: a report of three cases. | 1997 | Trop Doct | pmid:9133806 |
Winkler M et al. | [Incidence of inflammatory placental changes in threatened premature labor with and without additional antibiotic therapy]. | 1997 | Zentralbl Gynakol | pmid:9139498 |
Ye Z and Van Dyke K | Interaction of artemisinin and tetracycline or erythromycin against Plasmodium falciparum in vitro. | 1994 | Parasite | pmid:9140487 |
Florez C et al. | Susceptibilities of 55 strains of Neisseria meningitidis isolated in Spain in 1993 and 1994. | 1997 May-Jun | Chemotherapy | pmid:9142456 |
GarcÃa-Martos P et al. | Increase in high resistance to penicillin of clinical isolates of Streptococcus pneumoniae in Cádiz, Spain. | 1997 May-Jun | Chemotherapy | pmid:9142458 |
Tanaka T et al. | A new method to measure gastric emptying in conscious dogs: a validity study and effects of EM523 and L-NNA. | 1997 | Am. J. Physiol. | pmid:9142925 |
Knothe H | Medical implications of macrolide resistance and its relationship to the use of tylosin in animal feeds. | 1977 | Infection | pmid:914361 |
Cucchiara S et al. | Antroduodenal motor effects of intravenous erythromycin in children with abnormalities of gastrointestinal motility. | 1997 | J. Pediatr. Gastroenterol. Nutr. | pmid:9144124 |
Tsuruta S et al. | Effects of erythromycin, clarithromycin and rokitamycin on nifedipine metabolism in rats. | 1997 | Biol. Pharm. Bull. | pmid:9145220 |
Ng PC et al. | Erythromycin treatment for gastrointestinal dysmotility in preterm infants. | 1997 | J Paediatr Child Health | pmid:9145359 |
Wise R et al. | The activity of the methylpiperazinyl fluoroquinolone CG 5501: a comparison with other fluoroquinolones. | 1997 | J. Antimicrob. Chemother. | pmid:9145816 |
Sturm AW et al. | Over-the-counter availability of antimicrobial agents, self-medication and patterns of resistance in Karachi, Pakistan. | 1997 | J. Antimicrob. Chemother. | pmid:9145830 |
Ednie LM et al. | Susceptibilities of 228 penicillin- and erythromycin-susceptible and -resistant pneumococci to RU 64004, a new ketolide, compared with susceptibilities to 16 other agents. | 1997 | Antimicrob. Agents Chemother. | pmid:9145864 |
Ross JI et al. | Clinical resistance to erythromycin and clindamycin in cutaneous propionibacteria isolated from acne patients is associated with mutations in 23S rRNA. | 1997 | Antimicrob. Agents Chemother. | pmid:9145890 |
Schülin T et al. | In vitro activity of RU 64004, a new ketolide antibiotic, against gram-positive bacteria. | 1997 | Antimicrob. Agents Chemother. | pmid:9145901 |
Kendall BJ et al. | The effect of intravenous erythromycin on solid meal gastric emptying in patients with chronic symptomatic post-vagotomy-antrectomy gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9146779 |
Barrett MS and Jones RN | Antimicrobial activity and spectrum of sparfloxacin tested against erythromycin-resistant Streptococcus pneumoniae isolates. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:9147907 |
Panhuyzen-Goedkoop NM and Crijns HJ | [Iatrogenic collapse; can this be prevented?]. | 1997 | Ned Tijdschr Geneeskd | pmid:9148161 |
Watts JL and Salmon SA | Activity of selected antimicrobial agents against strains of Staphylococcus aureus isolated from bovine intramammary infections that produce beta-lactamase. | 1997 | J. Dairy Sci. | pmid:9149974 |
Colburn WA et al. | Pharmacokinetics of erythromycin on repetitive dosing. | 1977 | J Clin Pharmacol | pmid:915023 |
McDonald PJ et al. | Studies on absorption of a newly developed enteric-coated erythromycin base. | 1977 | J Clin Pharmacol | pmid:915024 |
Ehrmann EH | Infective endocarditis and practical guides for successful dentistry. | 1997 | Aust Dent J | pmid:9153847 |
Lengyel C et al. | [Erythrocyte-induced "torsade de pointes" ventricular tachycardia]. | 1997 | Orv Hetil | pmid:9153994 |
Carroll KC et al. | Susceptibility of beta-hemolytic streptococci to nine antimicrobial agents among four medical centers in Salt Lake City, Utah, USA. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9154408 |
Mitsuyama T et al. | Inhibition by erythromycin of human pulmonary artery endothelial cell injury induced by human neutrophils. | 1997 | Respiration | pmid:9154672 |
Matsuhashi M et al. | Cellular signals regulating antibiotic sensitivities of bacteria. | 1996 | Microb. Drug Resist. | pmid:9158728 |
Heaton MP and Handwerger S | Conjugative mobilization of a vancomycin resistance plasmid by a putative Enterococcus faecium sex pheromone response plasmid. | 1995 | Microb. Drug Resist. | pmid:9158753 |
Hessler PE et al. | Isolation of isoflavones from soy-based fermentations of the erythromycin-producing bacterium Saccharopolyspora erythraea. | 1997 | Appl. Microbiol. Biotechnol. | pmid:9163954 |
Sugihara E | Effect of macrolide antibiotics on neutrophil function in human peripheral blood. | 1997 | Kansenshogaku Zasshi | pmid:9164088 |
Yanagihara K et al. | [Efficacy of erythromycin inhalation in chronic respiratory infection caused by Pseudomonas aeruginosa]. | 1997 | Kansenshogaku Zasshi | pmid:9164089 |
Cheng CL et al. | Steady-state pharmacokinetics of delavirdine in HIV-positive patients: effect on erythromycin breath test. | 1997 | Clin. Pharmacol. Ther. | pmid:9164415 |
Lin JC and Quasny HA | QT prolongation and development of torsades de pointes with the concomitant administration of oral erythromycin base and quinidine. | 1997 May-Jun | Pharmacotherapy | pmid:9165570 |
Scalabrino G et al. | Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord. | 1997 | Exp. Neurol. | pmid:9168827 |
Somkuti GA et al. | Molecular properties of the erythromycin resistance plasmid pPV141 from Staphylococcus chromogenes. | 1997 | Plasmid | pmid:9169203 |
Leloup L et al. | Single-crossover integration in the Lactobacillus sake chromosome and insertional inactivation of the ptsI and lacL genes. | 1997 | Appl. Environ. Microbiol. | pmid:9172327 |
Koch B et al. | Construction of specific erythromycin resistance mutations in the temperate lactococcal bacteriophage TP901-1 and their use in studies of phage biology. | 1997 | Appl. Environ. Microbiol. | pmid:9172365 |
Piérard GE | [Pharma Clinics. Drug of the month. Benzamycin, an up-date on topical treatment of acne]. | 1997 | Rev Med Liege | pmid:9173479 |
Berg-Candolfi M et al. | Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression. | 1996 | Xenobiotica | pmid:9173679 |
Gibert Agulló A et al. | [Generalized acute exanthematous pustulosis: two case reports]. | 1997 | An. Esp. Pediatr. | pmid:9173852 |
Rybak MJ et al. | Pharmacodynamics of RP 59500 (quinupristin-dalfopristin) administered by intermittent versus continuous infusion against Staphylococcus aureus-infected fibrin-platelet clots in an in vitro infection model. | 1997 | Antimicrob. Agents Chemother. | pmid:9174199 |
Young H et al. | Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin. | 1997 | Int J STD AIDS | pmid:9175650 |
Resnick J et al. | Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. | 1997 | Am. J. Gastroenterol. | pmid:9177505 |
Hofstetter A | [Mycoplasma infections of the genito-urinary tract (author's transl)]. | 1977 | Schweiz. Rundsch. Med. Prax. | pmid:918003 |
Roe DE et al. | Mobile rRNA methylase genes coding for erythromycin resistance in Actinobacillus actinomycetemcomitans. | 1996 | J. Antimicrob. Chemother. | pmid:9182102 |
Xia HX et al. | Clarithromycin resistance in Helicobacter pylori: prevalence in untreated dyspeptic patients and stability in vitro. | 1996 | J. Antimicrob. Chemother. | pmid:9182104 |
Roblin PM et al. | In-vitro activity of dirithromycin against Chlamydia pneumoniae. | 1997 | J. Antimicrob. Chemother. | pmid:9184366 |
Reines HD et al. | Use of standard colon preparation in elective colectomy for carcinoma of the colon. | 1977 Nov-Dec | Rev Surg | pmid:918536 |
Hanada E et al. | Determination of erythromycin concentrations in rat plasma and liver by high-performance liquid chromatography with amperometric detection. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9188840 |
Huovinen P et al. | The relationship between erythromycin consumption and resistance in Finland. Finnish Study Group for Antimicrobial Resistance. | 1997 | Ciba Found. Symp. | pmid:9189633 |
Pacifico L et al. | Ureaplasma urealyticum and pulmonary outcome in a neonatal intensive care population. | 1997 | Pediatr. Infect. Dis. J. | pmid:9194108 |
Shimada T et al. | Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans. | 1997 | Arch. Toxicol. | pmid:9195021 |
Rendell DK and Callinan AP | Comparison of erythromycin and oxytetracycline for the treatment of virulent footrot in grazing sheep. | 1997 | Aust. Vet. J. | pmid:9196823 |
Baumüller A et al. | [Bacterial prostatitis--therapeutic principles]. | 1977 | Z Urol Nephrol | pmid:919805 |
Brückner R | Gene replacement in Staphylococcus carnosus and Staphylococcus xylosus. | 1997 | FEMS Microbiol. Lett. | pmid:9198277 |
Fons M et al. | Isolation and characterization of a plasmid from Lactobacillus fermentum conferring erythromycin resistance. | 1997 | Plasmid | pmid:9200223 |
Son R et al. | Antibiotic resistance and plasmid profile of Aeromonas hydrophila isolates from cultured fish, Telapia (Telapia mossambica). | 1997 | Lett. Appl. Microbiol. | pmid:9203404 |
Ishii M et al. | Erythromycin derivative improves gastric emptying and insulin requirement in diabetic patients with gastroparesis. | 1997 | Diabetes Care | pmid:9203450 |
Kabir I et al. | Erythromycin and trimethoprim-sulphamethoxazole in the treatment of cholera in children. | 1996 | J Diarrhoeal Dis Res | pmid:9203786 |
Caron D et al. | Skin tolerance of adapalene 0.1% gel in combination with other topical antiacne treatments. | 1997 | J. Am. Acad. Dermatol. | pmid:9204088 |
Rosser EJ | German shepherd dog pyoderma: a prospective study of 12 dogs. | 1997 Jul-Aug | J Am Anim Hosp Assoc | pmid:9204474 |
Monsieur I et al. | Severe community-acquired pneumonia caused by atypical organisms. | 1997 | Acta Clin Belg | pmid:9204587 |
PalacÃn C et al. | In vitro anti-Helicobacter pylori activity of ebrotidine. | 1997 | Arzneimittelforschung | pmid:9205746 |
Pacini N et al. | Antimicrobial susceptibility tests on anaerobic oral mixed cultures in periodontal diseases. | 1997 | J. Clin. Periodontol. | pmid:9205919 |