erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Altomare G et al. | Treatment of bullous pemphigoid with erythromycin: a reappraisal. | 1999 Oct-Nov | Eur J Dermatol | pmid:10610238 |
| Czeizel AE et al. | A population-based case-control teratologic study of oral erythromycin treatment during pregnancy. | 1999 Nov-Dec | Reprod. Toxicol. | pmid:10613401 |
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| National guideline for the management of Chlamydia trachomatis genital tract infection. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616372 | |
| National guideline for the management of non-gonococcal urethritis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases) | 1999 | Sex Transm Infect | pmid:10616373 | |
| National guideline for the management of early syphilis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616379 | |
| National guideline for the management of lymphogranuloma venereum. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616382 | |
| National guideline for the management of chancroid. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616383 | |
| Chieppa DM et al. | Effects of erythromycin on human colonic circular muscle in idiopathic chronic constipation. | 2000 | Eur. J. Clin. Invest. | pmid:10620004 |
| Novikova SI et al. | Introduction of a mini-gene encoding a five-amino acid peptide confers erythromycin resistance on Bacillus subtilis and provides temporary erythromycin protection in Proteus mirabilis. | 2000 | FEMS Microbiol. Lett. | pmid:10620668 |
| Desaki M et al. | Erythromycin suppresses nuclear factor-kappaB and activator protein-1 activation in human bronchial epithelial cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623585 |
| Kdesh A et al. | Effect of erythromycin on myocardial repolarization in patients with community-acquired pneumonia. | 1999 | South. Med. J. | pmid:10624910 |
| Gallardo MA and Thomas I | Hypersensitivity reaction to erythromycin. | 1999 | Cutis | pmid:10626100 |
| Lagrou K et al. | Macrolide resistance in Belgian Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:10629023 |
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| Sullivan S et al. | Stevens-Johnson syndrome secondary to erythromycin. | 1999 | Ann Pharmacother | pmid:10630839 |
| Trinkle R | Comment: evaluation of the clinical and financial impact of intravenous erythromycin therapy in hospitalized patients. | 1999 | Ann Pharmacother | pmid:10630842 |
| Puri SK and Singh N | Azithromycin: antimalarial profile against blood- and sporozoite-induced infections in mice and monkeys. | 2000 | Exp. Parasitol. | pmid:10631075 |
| Weston WL and Morelli JG | Steroid rosacea in prepubertal children. | 2000 | Arch Pediatr Adolesc Med | pmid:10632252 |
| Hypertrophic pyloric stenosis in infants following pertussis prophylaxis with erythromycin--Knoxville, Tennessee, 1999. | 1999 | MMWR Morb. Mortal. Wkly. Rep. | pmid:10634345 | |
| Nasrin D et al. | Antibiotic resistance in Streptococcus pneumoniae isolated from children. | 1999 | J Paediatr Child Health | pmid:10634983 |
| MartÃnez-Maldonado M | Postinfectious glomerulonephritis. | 2000 | Am. J. Kidney Dis. | pmid:10636819 |
| Wu YJ | Highlights of semi-synthetic developments from erythromycin A. | 2000 | Curr. Pharm. Des. | pmid:10637376 |
| Bajic S et al. | Analysis of erythromycin by liquid chromatography/mass spectrometry using involatile mobile phases with a novel atmospheric pressure ionization source. | 2000 | Rapid Commun. Mass Spectrom. | pmid:10637421 |
| Gisby J and Bryant J | Efficacy of a new cream formulation of mupirocin: comparison with oral and topical agents in experimental skin infections. | 2000 | Antimicrob. Agents Chemother. | pmid:10639346 |
| Brueggemann AB et al. | In vitro activity of ABT-773, a new ketolide, against recent clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. | 2000 | Antimicrob. Agents Chemother. | pmid:10639382 |
| Honma Y et al. | Effect of erythromycin on Shigella infection of Caco-2 cells. | 2000 | FEMS Immunol. Med. Microbiol. | pmid:10640609 |
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| Medhus AW et al. | Low-dose intravenous erythromycin: effects on postprandial and fasting motility of the small bowel. | 2000 | Aliment. Pharmacol. Ther. | pmid:10651665 |
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| Descheemaeker P et al. | Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumoniae isolates. | 2000 | J. Antimicrob. Chemother. | pmid:10660498 |
| Wilkinson B et al. | Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase. | 2000 | Chem. Biol. | pmid:10662692 |
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| Mordi MN et al. | Acid-catalyzed degradation of clarithromycin and erythromycin B: a comparative study using NMR spectroscopy. | 2000 | J. Med. Chem. | pmid:10669574 |
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