erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ragosta M et al. | Potentially fatal interaction between erythromycin and disopyramide. | 1989 | Am. J. Med. | pmid:2467560 |
Gumaste VV | Erythromycin-induced pancreatitis. | 1989 | Am. J. Med. | pmid:2729328 |
Curtis LH et al. | Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. | 2003 | Am. J. Med. | pmid:12586234 |
Nattel S et al. | Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism. | 1990 | Am. J. Med. | pmid:2382671 |
Klein JO | Emerging perspectives in management and prevention of infections of the respiratory tract in infants and children. | 1985 | Am. J. Med. | pmid:4014286 |
Rudin JE et al. | Failure of erythromycin in treatment of Legionella micdadei pneumonia. | 1984 | Am. J. Med. | pmid:6607673 |
Diehl AM et al. | Cholestatic hepatitis from erythromycin ethylsuccinate. Report of two cases. | 1984 | Am. J. Med. | pmid:6609640 |
Parker RH et al. | Erythromycin-resistant pneumococcal osteomyelitis. | 1970 | Am. J. Med. | pmid:5415405 |
Sacristán JA and Soto J | Erythromycin ototoxicity: methodology and conclusions. | 1993 | Am. J. Med. | pmid:8430720 |
Lipsky BA et al. | Ofloxacin treatment of Chlamydia pneumoniae (strain TWAR) lower respiratory tract infections. | 1990 | Am. J. Med. | pmid:2252040 |
Tablan OC and Reyes MP | Chronic interstitial pulmonary fibrosis following Mycoplasma pneumoniae pneumonia. | 1985 | Am. J. Med. | pmid:4025379 |
Augenbraun MH et al. | Chlamydia pneumoniae pneumonia with pleural effusion: diagnosis by culture. | 1991 | Am. J. Med. | pmid:1951390 |
Swanson DJ et al. | Erythromycin ototoxicity: prospective assessment with serum concentrations and audiograms in a study of patients with pneumonia. | 1992 | Am. J. Med. | pmid:1731511 |
Bolton WK et al. | Ventriculojugular shunt nephritis with Corynebacterium bovis. Successful therapy with antibiotics. | 1975 | Am. J. Med. | pmid:1163549 |
Stocks JM et al. | Ofloxacin in community-acquired lower respiratory infections. A comparison with amoxicillin or erythromycin. | 1989 | Am. J. Med. | pmid:2690620 |
Bowler WA et al. | Gastrointestinal side effects of intravenous erythromycin: incidence and reduction with prolonged infusion time and glycopyrrolate pretreatment. | 1992 | Am. J. Med. | pmid:1546723 |
Bor DH and Himmelstein DU | Endocarditis prophylaxis for patients with mitral valve prolapse. A quantitative analysis. | 1984 | Am. J. Med. | pmid:6711576 |
Unertl KE et al. | Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. | 1989 | Am. J. Med. | pmid:2589356 |
Trimble GX | Acute pancreatitis induced by erythromycin. | 1989 | Am. J. Med. | pmid:2589410 |
SOLOMON S and JOHNSTON B | The clinical use of erythromycin. | 1955 | Am. J. Med. Sci. | pmid:13268445 |
Kislak JW et al. | Susceptibility of pneumococci to nine antibiotics. | 1965 | Am. J. Med. Sci. | pmid:4378532 |
Kayser FH and Mak TM | Methicillin-resistant staphylococci. | 1972 | Am. J. Med. Sci. | pmid:4486503 |
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Simon HJ | Antimicrobial susceptibility of group D hemolytic streptococci (enterococci). | 1967 | Am. J. Med. Sci. | pmid:5180810 |
BLOUGH HA et al. | Serum levels and clinical results with erythromycin propionate. | 1960 | Am. J. Med. Sci. | pmid:13801645 |
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ROBINSON MM | Hepatic dysfunction associated with triacetyloleandomycin and propionyl erythromycin ester lauryl sulfate. | 1962 | Am. J. Med. Sci. | pmid:14492926 |
Devasia RA et al. | Compliance with azithromycin versus erythromycin in the setting of a pertussis outbreak. | 2009 | Am. J. Med. Sci. | pmid:19301451 |
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HIRSCH HA and FINLAND M | Effect of food on the absorption of erythromycin propionate, erythromycin stearate and triacetyloleandomycin. | 1959 | Am. J. Med. Sci. | pmid:13661157 |
Holoshitz J et al. | Listeria monocytogenes pericarditis in a chronically hemodialyzed patient. | 1984 Jul-Aug | Am. J. Med. Sci. | pmid:6465192 |
Feigin RD et al. | Treatment of penicillin-resistant staphylococcal infections with clindamycin. | 1971 | Am. J. Med. Sci. | pmid:5578775 |
GRIFFITH RS and BLACK HR | COMPARISON OF THE BLOOD LEVELS OBTAINED AFTER SINGLE AND MULTIPLE DOSES OF ERYTHROMYCIN ESTOLATE AND ERYTHROMYCIN STEARATE. | 1964 | Am. J. Med. Sci. | pmid:14106882 |
RodrÃguez-Gutiérrez R et al. | Herpes zoster ophthalmicus masked by hymenoptera stings. | 2014 | Am. J. Med. Sci. | pmid:23085675 |
HIRSCH HA et al. | Effect of food on absorption of a new form of erythromycin propionate. | 1960 | Am. J. Med. Sci. | pmid:14401969 |
McGehee RF et al. | Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. | 1968 | Am. J. Med. Sci. | pmid:4386950 |
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CLAPPER WE et al. | THE SUSCEPTIBILITY OF CERTAIN BACTERIA TO LINCOMYCIN AS RELATED TO ATTAINABLE SERUM LEVELS IN HUMAN ADULTS. | 1964 | Am. J. Med. Sci. | pmid:14130319 |
FISCHER HW and HOAK JC | MIMICRY OF ACUTE CHOLECYSTITIS BY ERYTHROMYCIN ESTOLATE REACTIONS. REPORT OF 2 CASES. | 1964 | Am. J. Med. Sci. | pmid:14130320 |
McCabe WR and Lorian V | Comparison of the antibacterial activity of rifampicin and other antibiotics. | 1968 | Am. J. Med. Sci. | pmid:4387027 |
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Baird IM et al. | Case report. Clinical manifestations and treatment of Legionnaires' disease. | 1979 Mar-Apr | Am. J. Med. Sci. | pmid:463949 |
Gray BM | Case report: Rhodococcus equi pneumonia in a patient infected by the human immunodeficiency virus. | 1992 | Am. J. Med. Sci. | pmid:1595781 |
Rao KV and Ralston RA | Meningitis due to Campylobacter fetus intestinalis in a kidney transplant recipient. A case report. | 1987 | Am. J. Nephrol. | pmid:3324765 |
Friberg J | Genital mycoplasma infections. | 1978 | Am. J. Obstet. Gynecol. | pmid:362924 |
Alger LS and Lovchik JC | Comparative efficacy of clindamycin versus erythromycin in eradication of antenatal Chlamydia trachomatis. | 1991 | Am. J. Obstet. Gynecol. | pmid:1872343 |
Ehsanipoor RM et al. | A retrospective review of ampicillin-sulbactam and amoxicillin + clavulanate vs cefazolin/cephalexin and erythromycin in the setting of preterm premature rupture of membranes: maternal and neonatal outcomes. | 2008 | Am. J. Obstet. Gynecol. | pmid:18455521 |
Yost NP et al. | An appraisal of treatment guidelines for antepartum community-acquired pneumonia. | 2000 | Am. J. Obstet. Gynecol. | pmid:10920320 |
Keelan JA et al. | Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. | 2011 | Am. J. Obstet. Gynecol. | pmid:21481833 |