erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Endocarditis, Bacterial D004697 5 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Endometritis D004716 6 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Epilepsy D004827 35 associated lipids
Ergotism D004881 4 associated lipids
Erysipelas D004886 1 associated lipids
Erythema Multiforme D004892 3 associated lipids
Erythema Nodosum D004893 5 associated lipids
Erythrasma D004894 1 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Eye Diseases D005128 12 associated lipids
Factor X Deficiency D005171 2 associated lipids
Fecal Incontinence D005242 1 associated lipids
Femoral Fractures D005264 7 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Fever D005334 35 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Folliculitis D005499 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Foot Diseases D005534 4 associated lipids
Fractures, Open D005597 3 associated lipids
Furunculosis D005667 2 associated lipids
Gangrene D005734 3 associated lipids
Gardner Syndrome D005736 2 associated lipids
Gas Gangrene D005738 1 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Tourette Syndrome D005879 3 associated lipids
Glomerulonephritis D005921 35 associated lipids
Gonorrhea D006069 7 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Haemophilus Infections D006192 3 associated lipids
Hand Dermatoses D006229 5 associated lipids
Hearing Disorders D006311 10 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Heart Block D006327 3 associated lipids
Heart Diseases D006331 8 associated lipids
Cardiomegaly D006332 31 associated lipids
Heart Failure D006333 36 associated lipids
Heart Murmurs D006337 1 associated lipids
Hematemesis D006396 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kuwahara T et al. Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. 2013 J. Cardiovasc. Electrophysiol. pmid:23551640
Lozada LE et al. Development of pyloric stenosis after a 4-day course of oral erythromycin. 2013 Pediatr Emerg Care pmid:23558266
Cuello-García CA et al. Treating BCG-induced disease in children. 2013 Cochrane Database Syst Rev pmid:23440826
Jersild Jespersen M et al. [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. 2013 Ugeskr. Laeg. pmid:23462037
Jiang M and Pfeifer BA Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. 2013 Metab. Eng. pmid:23747605
Xia Q et al. Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. 2013 BMC Microbiol. pmid:23767761
Yun SH et al. Demodex folliculitis presenting as periocular vesiculopustular rash. 2013 Orbit pmid:23895342
Nie XP et al. Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole exposure to the antioxidant system in Pseudokirchneriella subcapitata. 2013 Environ. Pollut. pmid:22982550
Pelchovich G et al. The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics. 2013 Int. J. Med. Microbiol. pmid:23972615
Ishihara K et al. Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan. 2013 Microbiol. Immunol. pmid:23930694
Pedersen JM et al. Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). 2013 Toxicol. Sci. pmid:24014644
Zhang L et al. Design, synthesis and biological evaluation of azithromycin glycosyl derivatives as potential antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23937982
Herath SC and Poole P Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). 2013 Cochrane Database Syst Rev pmid:24288145
Liang JH and Han X Structure-activity relationships and mechanism of action of macrolides derived from erythromycin as antibacterial agents. 2013 Curr Top Med Chem pmid:24200358
Matejcek A and Goldman RD Treatment and prevention of ophthalmia neonatorum. 2013 Can Fam Physician pmid:24235191
Kamal A et al. Anti-tubercular agents. Part 8: synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazoles. 2013 Bioorg. Med. Chem. Lett. pmid:24206766
Rallis E et al. Topical 5% benzoyl peroxide and 3% erythromycin gel: experience with 191 patients with papulopustular acne. 2013 Acta Dermatovenerol Croat pmid:24183219
Sugino K et al. Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. 2013 Intern. Med. pmid:24292765
Goh S et al. Phage Ï•C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. 2013 MBio pmid:24255122
Horácio AN et al. The majority of adult pneumococcal invasive infections in Portugal are still potentially vaccine preventable in spite of significant declines of serotypes 1 and 5. 2013 PLoS ONE pmid:24066064
Guo L et al. Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. 2013 Toxicol. Sci. pmid:24052561
Guo MT et al. Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. 2013 Chemosphere pmid:24055024
Hirano E et al. Erythromycin treatment suppresses myocardial injury in autoimmune myocarditis in rats via suppression of superoxide production. 2013 Int. J. Cardiol. pmid:22727964
Wang HB et al. Molecular epidemiological analysis of group A Streptococci isolated from children in Chaoyang District of Beijing, 2011: emm types, virulence factor genes and erythromycin resistant genes. 2013 Biomed. Environ. Sci. pmid:24099615
Wang X et al. Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. 2013 ACS Appl Mater Interfaces pmid:24150740
Wu C et al. Identification of elaiophylin derivatives from the marine-derived actinomycete Streptomyces sp. 7-145 using PCR-based screening. 2013 J. Nat. Prod. pmid:24164206
Arao M et al. Clostridium difficile colitis induced by long-term low-dosage erythromycin. 2013 Pediatr. Infect. Dis. J. pmid:24008746
Li YY et al. Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. 2013 BMC Genomics pmid:23902230
Kirm B et al. SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea. 2013 Microb. Cell Fact. pmid:24341557
Olender A et al. The cause of Actinomyces canalictulis--a case study. 2013 Ann Agric Environ Med pmid:24364446
Yin YD et al. [Survey of macrolide resistance in Mycoplasma pneumoniae in adult patients with community-acquired pneumonia in Beijing, China]. 2013 Zhonghua Jie He He Hu Xi Za Zhi pmid:24503430
Cai G et al. Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. 2013 J. Nat. Prod. pmid:24224794
Ong SJ et al. Staphylococcus aureus keratitis: a review of hospital cases. 2013 PLoS ONE pmid:24244625
Chroboczek T et al. Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. 2013 PLoS ONE pmid:24260092
Ansari NN et al. Treatment of chronic rhinosinusitis using erythromycin phonophoresis. 2013 Physiother Theory Pract pmid:22891948
Fang J et al. Dissecting the function of a protruding loop in AcrB trimerization. 2013 J. Biomol. Struct. Dyn. pmid:22877148
Chen DK et al. [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. 2013 Zhonghua Yi Xue Za Zhi pmid:24548451
Opdam FL et al. Breath tests to phenotype drug disposition in oncology. 2013 Clin Pharmacokinet pmid:23868281
Tsujimoto M et al. Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. 2013 Toxins (Basel) pmid:23965431
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
Broad J and Sanger GJ The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. 2013 Br. J. Pharmacol. pmid:23190027
Hao H et al. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. 2013 Antimicrob. Agents Chemother. pmid:23274667
Prabu D and Menon T Genotyping of erythromycin resistant group C & G streptococci isolated in Chennai, south India. 2013 Indian J. Med. Res. pmid:23481067
Zhang Y et al. Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23481648
Koulaouzidis A et al. Do prokinetics influence the completion rate in small-bowel capsule endoscopy? A systematic review and meta-analysis. 2013 Curr Med Res Opin pmid:23790243
Lin MH et al. Penetration of erythromycin through Staphylococcus epidermidis biofilm. 2013 Chin. Med. J. pmid:23876889
Winnicka K et al. The effect of PAMAM dendrimers on the antibacterial activity of antibiotics with different water solubility. 2013 Molecules pmid:23881050
Hennenberg M et al. The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction. 2013 J. Biomed. Sci. pmid:23815815
Mu Y et al. Synergistic effects of anti-CmeA and anti-CmeB peptide nucleic acids on sensitizing Campylobacter jejuni to antibiotics. 2013 Antimicrob. Agents Chemother. pmid:23817373
González-Abad MJ and Alonso-Sanz M [Incidence and susceptibility of Campylobacter jejuni in pediatric patients: involvement in bacteremia]. 2013 Rev Esp Quimioter pmid:23817644
Sanz-Rodríguez N et al. [Accuracy of Etest method to study Campylobacter spp. susceptibility to erythromycin, ciprofloxacin and tetracycline]. 2013 Rev Esp Quimioter pmid:23817649
James GD et al. Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. 2013 Prim Care Respir J pmid:23839240
Parhi AK et al. Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. 2013 Bioorg. Med. Chem. Lett. pmid:23891185
Lee A Gastroparesis: what is the current state-of-the-art for evaluation and medical management? What are the results? 2013 J. Gastrointest. Surg. pmid:23801519
Liu ZX et al. [Inhibition of methanogenium by erythromycin and its domestation]. 2013 Huan Jing Ke Xue pmid:23798140
Pasquini L et al. Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. 2013 Sci. Total Environ. pmid:23827359
Malinka W et al. Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes. 2013 Bioorg. Med. Chem. pmid:23850103
Weber JM et al. Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations. 2013 Appl. Microbiol. Biotechnol. pmid:23604533
Chen Y et al. Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. 2013 Bioprocess Biosyst Eng pmid:23361182
Melnik BC and Schmitz G Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1? 2013 Exp. Dermatol. pmid:23800068
Wittwer MB et al. Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. 2013 J. Med. Chem. pmid:23241029
Gao X et al. Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation. 2013 J. Am. Chem. Soc. pmid:23464668
Kelmer G et al. Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic, or palmar digital veins in standing horses. 2013 J. Vet. Pharmacol. Ther. pmid:23240633
Oplinger RW and Wagner EJ Control of Flavobacterium psychrophilum: tests of erythromycin, streptomycin, osmotic and thermal shocks, and rapid pH change. 2013 J. Aquat. Anim. Health pmid:23241009
Chae HS et al. Use of a novel Escherichia coli-leuconostoc shuttle vector for metabolic engineering of Leuconostoc citreum to overproduce D-lactate. 2013 Appl. Environ. Microbiol. pmid:23241984
Papapetropoulos N et al. Abscesses and wound infections due to Staphylococcus lugdunensis: report of 16 cases. 2013 Infection pmid:23242962
Berger A et al. Two cases of cutaneous diphtheria associated with occupational pig contact in Germany. 2013 Zoonoses Public Health pmid:23280311
Juntunen P et al. Absence of tetracycline resistance in Campylobacter coli isolates from Finnish finishing pigs treated with chlortetracycline. 2013 J. Appl. Microbiol. pmid:23282197
Mavri A and Smole Možina S Resistance to bile salts and sodium deoxycholate in macrolide- and fluoroquinolone-susceptible and resistant Campylobacter jejuni and Campylobacter coli strains. 2013 Microb. Drug Resist. pmid:23289436
Lin KJ et al. Safety of macrolides during pregnancy. 2013 Am. J. Obstet. Gynecol. pmid:23254249
Sánchez Valenzuela A et al. Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods. 2013 Foodborne Pathog. Dis. pmid:23259502
Sanad YM et al. Molecular epidemiology and public health relevance of Campylobacter isolated from dairy cattle and European starlings in Ohio, USA. 2013 Foodborne Pathog. Dis. pmid:23259503
Haruna M et al. Prevalence and antimicrobial resistance of Campylobacter isolates from beef cattle and pigs in Japan. 2013 J. Vet. Med. Sci. pmid:23220905
Javid FA et al. Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. 2013 Eur. J. Pharmacol. pmid:23201066
Goodman CD et al. Chemobiosynthesis of new antimalarial macrolides. 2013 Antimicrob. Agents Chemother. pmid:23208707
Li X et al. Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. 2013 Eur J Med Chem pmid:23229056
Nunez-Samudio V and Chesneau O Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. 2013 Res. Microbiol. pmid:23261969
Hisatsune J et al. Emergence of Staphylococcus aureus carrying multiple drug resistance genes on a plasmid encoding exfoliative toxin B. 2013 Antimicrob. Agents Chemother. pmid:24080652
Lim CH et al. Effect of DA-9701 on gastric emptying in a mouse model: assessment by ¹³C-octanoic acid breath test. 2013 World J. Gastroenterol. pmid:23885150
Paterna A et al. Short communication: In vitro antimicrobial susceptibility of Mycoplasma agalactiae strains isolated from dairy goats. 2013 J. Dairy Sci. pmid:24035026
Teske L et al. Epidemiological investigations on the possible risk of distribution of zoonotic bacteria through apparently healthy homing pigeons. 2013 Avian Pathol. pmid:23930968
Lins RX et al. Antimicrobial resistance and virulence traits of Enterococcus faecalis from primary endodontic infections. 2013 J Dent pmid:23851130
Rożynek E et al. Emergence of macrolide-resistant Campylobacter strains in chicken meat in Poland and the resistance mechanisms involved. 2013 Foodborne Pathog. Dis. pmid:23638847
Dubey D et al. A report on infection dynamics of inducible clindamycin resistance of Staphylococcus aureus isolated from a teaching hospital in India. 2013 Asian Pac J Trop Biomed pmid:23593595
Liang JH et al. Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. 2013 Bioorg. Med. Chem. Lett. pmid:23375796
Drago L et al. Phenotypic and genotypic antibiotic resistance in some probiotics proposed for medical use. 2013 Int. J. Antimicrob. Agents pmid:23313535
Sanger GJ et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. 2013 Br. J. Pharmacol. pmid:23189978
Rams TE et al. Antibiotic susceptibility of periodontal Enterococcus faecalis. 2013 J. Periodontol. pmid:23106507
Osterman IA et al. A nascent proteome study combining click chemistry with 2DE. 2013 Proteomics pmid:23161590
Metzler K et al. Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae. 2013 J. Antimicrob. Chemother. pmid:23169894
Elborn JS and Tunney MM Macrolides and bronchiectasis: clinical benefit with a resistance price. 2013 JAMA pmid:23532247
Chan BC et al. Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase. 2013 Phytomedicine pmid:23541215
Tarran R et al. Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. 2013 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:23542952
Reveiz L and Cardona AF Antibiotics for acute laryngitis in adults. 2013 Cochrane Database Syst Rev pmid:23543536
Moriya S et al. Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. 2013 Int. J. Oncol. pmid:23546223
Akiyoshi T et al. Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants. 2013 Drug Metab. Pharmacokinet. pmid:23514827
Müller W et al. German Francisella tularensis isolates from European brown hares (Lepus europaeus) reveal genetic and phenotypic diversity. 2013 BMC Microbiol. pmid:23517149
Lasnier O et al. Two cases of corneal abrasions in children exposed to liquid detergent capsules. 2013 Can. J. Ophthalmol. pmid:23561618
Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern. 2013 Indian J. Med. Res. pmid:23563381
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400