erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Endocarditis, Bacterial D004697 5 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Endometritis D004716 6 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Epilepsy D004827 35 associated lipids
Ergotism D004881 4 associated lipids
Erysipelas D004886 1 associated lipids
Erythema Multiforme D004892 3 associated lipids
Erythema Nodosum D004893 5 associated lipids
Erythrasma D004894 1 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Eye Diseases D005128 12 associated lipids
Factor X Deficiency D005171 2 associated lipids
Fecal Incontinence D005242 1 associated lipids
Femoral Fractures D005264 7 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Fever D005334 35 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Folliculitis D005499 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Foot Diseases D005534 4 associated lipids
Fractures, Open D005597 3 associated lipids
Furunculosis D005667 2 associated lipids
Gangrene D005734 3 associated lipids
Gardner Syndrome D005736 2 associated lipids
Gas Gangrene D005738 1 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Tourette Syndrome D005879 3 associated lipids
Glomerulonephritis D005921 35 associated lipids
Gonorrhea D006069 7 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Haemophilus Infections D006192 3 associated lipids
Hand Dermatoses D006229 5 associated lipids
Hearing Disorders D006311 10 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Heart Block D006327 3 associated lipids
Heart Diseases D006331 8 associated lipids
Cardiomegaly D006332 31 associated lipids
Heart Failure D006333 36 associated lipids
Heart Murmurs D006337 1 associated lipids
Hematemesis D006396 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Stieler AL et al. Macrolide-induced hyperthermia in foals: Role of impaired sweat responses. 2016 Equine Vet. J. pmid:26174202
Kumpfmüller J et al. Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis. 2016 Appl. Microbiol. Biotechnol. pmid:26432460
Deloose E et al. Higher plasma motilin levels in obese patients decrease after Roux-en-Y gastric bypass surgery and regulate hunger. 2016 Gut pmid:25986945
Talebi M et al. Determination of Characteristics of Erythromycin Resistant Streptococcus pneumoniae with Preferred PCV Usage in Iran. 2016 PLoS ONE pmid:28033345
Ray D et al. Molecular characterization and evaluation of the emerging antibiotic-resistant Streptococcus pyogenes from eastern India. 2016 BMC Infect. Dis. pmid:27955635
Ma Y et al. Antimicrobial activity of topical agents against Propionibacterium acnes: an in vitro study of clinical isolates from a hospital in Shanghai, China. 2016 Front Med pmid:27896620
Zmantar T et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. 2016 Microb. Pathog. pmid:27816681
Barbanti F and Spigaglia P Characterization of Clostridium difficile PCR-ribotype 018: A problematic emerging type. 2016 Anaerobe pmid:27725230
DeLorenzo ME et al. Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. 2016 Environ. Toxicol. pmid:25348372
Hadjipanayis A et al. Nasopharyngeal Pneumococcal Carriage among Healthy Children in Cyprus Post Widespread Simultaneous Implementation of PCV10 and PCV13 Vaccines. 2016 PLoS ONE pmid:27706247
Krishnamoorthy G et al. Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane. 2016 Antimicrob. Agents Chemother. pmid:27697764
Li M et al. Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China. 2016 Int J Mol Sci pmid:27669217
Xu JY et al. Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. 2016 J. Proteome Res. pmid:27090497
Murchison L et al. Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. 2016 Pediatr. Surg. Int. pmid:27655365
Dzyubak E and Yap MN The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling. 2016 Antimicrob. Agents Chemother. pmid:27645242
Abreu AC et al. Combinatorial approaches with selected phytochemicals to increase antibiotic efficacy against Staphylococcus aureus biofilms. 2016 Biofouling pmid:27643487
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Hu Z et al. Short-term performance of enhanced biological phosphorus removal (EBPR) system exposed to erythromycin (ERY) and oxytetracycline (OTC). 2016 Bioresour. Technol. pmid:27631889
Benamrouche N et al. Microbiological and molecular characterization of Corynebacterium diphtheriae isolated in Algeria between 1992 and 2015. 2016 Clin. Microbiol. Infect. pmid:27585941
Kang CH and So JS Antibiotic and heavy metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea, Korea. 2016 Mar. Pollut. Bull. pmid:27555484
Rizzotti L et al. Biocide and antibiotic resistance of Enterococcus faecalis and Enterococcus faecium isolated from the swine meat chain. 2016 Food Microbiol. pmid:27554158
Choe YJ et al. Emergence of antibiotic-resistant non-vaccine serotype pneumococci in nasopharyngeal carriage in children after the use of extended-valency pneumococcal conjugate vaccines in Korea. 2016 Vaccine pmid:27546875
Kang CH et al. Antimicrobial susceptibility of Vibrio alginolyticus isolated from oyster in Korea. 2016 Environ Sci Pollut Res Int pmid:27543129
Metcalf BJ et al. Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States. 2016 Clin. Microbiol. Infect. pmid:27542334
Parasrampuria DA et al. Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. 2016 Br J Clin Pharmacol pmid:27530188
Yuan QB et al. Reductions of bacterial antibiotic resistance through five biological treatment processes treated municipal wastewater. 2016 Environ Sci Pollut Res Int pmid:27384166
Karlsson E et al. Clonality of erythromycin resistance in Francisella tularensis. 2016 J. Antimicrob. Chemother. pmid:27334667
Changchien CH et al. Antibiotic susceptibility and genomic variations in Staphylococcus aureus associated with Skin and Soft Tissue Infection (SSTI) disease groups. 2016 BMC Infect. Dis. pmid:27287530
Waiser MJ et al. Effects of erythromycin, trimethoprim and clindamycin on attached microbial communities from an effluent dominated prairie stream. 2016 Ecotoxicol. Environ. Saf. pmid:27261880
Karničar K et al. Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea. 2016 Microb. Cell Fact. pmid:27255285
Ghosh S and Banerjee M Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus. 2016 Indian J. Med. Res. pmid:27241651
Pignatello R et al. Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. 2016 Eur J Med Chem pmid:27236014
Mushtaq A et al. Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva. 2016 Antimicrob. Agents Chemother. pmid:27216060
Hong M et al. Impacts of proline on the central metabolism of an industrial erythromycin-producing strain Saccharopolyspora erythraea via (13)C labeling experiments. 2016 J. Biotechnol. pmid:27215341
Stacevičienė I et al. Antibiotic resistance of Streptococcus pneumoniae, isolated from nasopharynx of preschool children with acute respiratory tract infection in Lithuania. 2016 BMC Infect. Dis. pmid:27206423
Tatiya-Aphiradee N et al. In vivo antibacterial activity of Garcinia mangostana pericarp extract against methicillin-resistant Staphylococcus aureus in a mouse superficial skin infection model. 2016 Pharm Biol pmid:27180784
Trac MH et al. Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. 2016 CMAJ pmid:26903359
He M et al. Mechanism of synergy between SIPI-8294 and β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. 2016 Lett. Appl. Microbiol. pmid:27173151
Patel MB et al. Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. 2016 Bioorg. Med. Chem. pmid:27166575
Mendes RE et al. In Vitro Activity of Lefamulin Tested against Streptococcus pneumoniae with Defined Serotypes, Including Multidrug-Resistant Isolates Causing Lower Respiratory Tract Infections in the United States. 2016 Antimicrob. Agents Chemother. pmid:27161634
Taylor SJ et al. A randomised controlled feasibility and proof-of-concept trial in delayed gastric emptying when metoclopramide fails: We should revisit nasointestinal feeding versus dual prokinetic treatment: Achieving goal nutrition in critical illness and delayed gastric emptying: Trial of nasointestinal feeding versus nasogastric feeding plus prokinetics. 2016 Clin Nutr ESPEN pmid:28531392
Tan C et al. Effects of Low-Dose and Long-Term Treatment with Erythromycin on Interleukin-17 and Interleukin-23 in Peripheral Blood and Induced Sputum in Patients with Stable Chronic Obstructive Pulmonary Disease. 2016 Mediators Inflamm. pmid:27127346
Guo Q et al. Controlling the feed rate of propanol to optimize erythromycin fermentation by on-line capacitance and oxygen uptake rate measurement. 2016 Bioprocess Biosyst Eng pmid:26615414
Zheng Z et al. Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. 2016 J. Antibiot. pmid:27118243
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Chen Y et al. TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. 2016 Carbohydr Polym pmid:27083368
Diawara I et al. Phenotypic and genotypic characterization of Streptococcus pneumoniae resistant to macrolide in Casablanca, Morocco. 2016 Infect. Genet. Evol. pmid:26961592
Sierra-Arguello YM et al. Fluoroquinolone and macrolide resistance in Campylobacter jejuni isolated from broiler slaughterhouses in southern Brazil. 2016 Avian Pathol. pmid:26925976
Molina-Manso D et al. Effect of different agents with potential antibiofilm activity on antimicrobial susceptibility of biofilms formed by Staphylococcus spp. isolated from implant-related infections. 2016 J. Antibiot. pmid:26905757
Madmanang S et al. Constituents of Fagraea fragrans with Antimycobacterial Activity in Combination with Erythromycin. 2016 J. Nat. Prod. pmid:26905094
Argyropoulos P et al. Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. 2016 Biochim. Biophys. Acta pmid:26592346
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Jin Y et al. From the Cover: Exposure to Oral Antibiotics Induces Gut Microbiota Dysbiosis Associated with Lipid Metabolism Dysfunction and Low-Grade Inflammation in Mice. 2016 Toxicol. Sci. pmid:27503388
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Bouvet L et al. Ultrasound Assessment of the Prokinetic Effect of Erythromycin in Trauma Patients with a Full Stomach: A Case Series. 2016 Anesth. Analg. pmid:26859878
Moltó-García B et al. Molecular characterization and antimicrobial susceptibility of hemolytic Streptococcus agalactiae from post-menopausal women. 2016 Maturitas pmid:26857873
Sari E et al. Fabrication of surface plasmon resonance nanosensor for the selective determination of erythromycin via molecular imprinted nanoparticles. 2016 Talanta pmid:26838449
Magnussen MD et al. Antibacterial resistance in Streptococcus pyogenes (GAS) from healthy carriers and tonsillitis patients and association with antibacterial sale in the Faroe Islands. 2016 APMIS pmid:26833774
Seki M et al. A Chronic Respiratory Pasteurella multocida Infection Is Well-Controlled by Long-Term Macrolide Therapy. 2016 Intern. Med. pmid:26831030
Deloose E et al. The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway. 2016 Am. J. Clin. Nutr. pmid:26817505
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Chuang MC et al. Diffuse panbronchiolitis-The response and recurrence after erythromycin therapy. 2016 J. Formos. Med. Assoc. pmid:26705139
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Ishikawa Y et al. Inactivation kinetics and residual activity of CYP3A4 after treatment with erythromycin. 2017 Biopharm Drug Dispos pmid:28425104
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Liu J et al. Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. 2017 Metab. Eng. pmid:27794466
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