erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Bergan T | [Erythromycin instead of tetracyclines to children]. | 1978 | Tidsskr. Nor. Laegeforen. | pmid:684704 |
Halstensen A et al. | [Treatment of infections caused by group A beta-hemolytic streptococci]. | 1990 | Tidsskr. Nor. Laegeforen. | pmid:2120791 |
Ose L | [Encephalitis associated with mycoplasma pneumoniae infection in children]. | 1975 | Tidsskr. Nor. Laegeforen. | pmid:1145545 |
Lind O and Harthug S | [Hearing loss after erythromycin therapy]. | 1993 | Tidsskr. Nor. Laegeforen. | pmid:8211901 |
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Hassel B | [Acute hypothermia and adverse effects on the central nervous system during erythromycin therapy]. | 1994 | Tidsskr. Nor. Laegeforen. | pmid:7915859 |
Itoh T and Kasahara S | Rat T lymphocyte progenitors in bone marrow can be induced to express more Thy 1. | 1985 | Thymus | pmid:2865831 |
Johnsson H and Niklasson PM | Effects of some antibiotics of platelet function in vitro and in vivo. | 1977 | Thromb. Res. | pmid:905975 |
Yousaf N et al. | Long-term low-dose erythromycin in patients with unexplained chronic cough: a double-blind placebo controlled trial. | 2010 | Thorax | pmid:20965928 |
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Waterworth PM et al. | A critical investigation into the antibiotic sterilization of heart valve homografts. | 1974 | Thorax | pmid:4368321 |
Dorrell L et al. | Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. | 1994 | Thorax | pmid:8016806 |
White RJ | Why use erythromycin? | 1994 | Thorax | pmid:7974308 |
Oaklay CM | Prevention of infective endocarditis. | 1979 | Thorax | pmid:542909 |
Brennan S et al. | Directed neutrophil migration to IL-8 is increased in cystic fibrosis: a study of the effect of erythromycin. | 2001 | Thorax | pmid:11120907 |
Ellis ME and Dunbar EM | In vivo response of acute Q fever to erythromycin. | 1982 | Thorax | pmid:7164010 |
Domingo C et al. | Radiographic appearance of nosocomial legionnaires' disease after erythromycin treatment. | 1991 | Thorax | pmid:1948796 |
Venkatesan P et al. | A hospital study of community acquired pneumonia in the elderly. | 1990 | Thorax | pmid:2356552 |
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Sobradillo V et al. | Antibiotic treatment in pneumonia due to Q fever. | 1992 | Thorax | pmid:1585291 |
McCulloch AJ et al. | Severe steroid responsive pneumonitis associated with pyoderma gangrenosum and ulcerative colitis. | 1985 | Thorax | pmid:4023983 |
Rogers GB et al. | Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. | 2013 | Thorax | pmid:23564400 |
GROTHUESMANN HG | [DEVELOPMENT OF RESISTANCE OF PATHOGENIC URINARY BACTERIA TO THE MOST COMMON ANTIBIOTICS]. | 1964 | Therapiewoche | pmid:14143496 |
Lagier G et al. | [A minor case of ergotism appearing to be connected with a potentialisation of ergotamine tartrate by erythromycine ethyl-succinate (author's transl)]. | 1979 Jul-Aug | Therapie | pmid:531783 |
Bergogne-Berezin E et al. | [Experimental study of the possible influence of a fluidifying agent (bromhexine) on the penetration of erythromycine into bronchial secretions (author's transl)]. | 1979 Nov-Dec | Therapie | pmid:547444 |
Baldit C et al. | [Influence of a new macrolide, dirithromycine, on the clearance of antipyrine]. | 1987 May-Jun | Therapie | pmid:3660320 |
Bavoux F | [Torsades de pointes and anti-infective agents]. | 1992 Sep-Oct | Therapie | pmid:1299973 |
VIALLIER J et al. | [Study of the blood levels obtained with 2 new esters of erythromycin: propionyl erythromycin and propionyl erythromycin lauryl sulfate]. | 1961 Nov-Dec | Therapie | pmid:13925737 |
Kanfer A et al. | [Erythromycin ototoxicity in patients with renal insufficiency (author's transl)]. | 1980 May-Jun | Therapie | pmid:7423428 |
Hugues FC et al. | [Cochlear toxicity of erythromycin in elderly patients]. | 1984 Sep-Oct | Therapie | pmid:6506017 |
TREFOUEL J et al. | [Not Available]. | 1959 | Therapie | pmid:13647435 |
Moutard I et al. | In vitro effects of spiramycin and dirithromycin on IL1 beta production by human LPS-stimulated mononuclear cells. | 1999 Sep-Oct | Therapie | pmid:10667098 |
Hoppe JE | [Pertussis: current aspects of diagnosis, therapy and prevention]. | 1998 | Ther Umsch | pmid:9492614 |
Meyer JC and Eichmann A | [Serodiagnosis and therapy of syphilis]. | 1985 | Ther Umsch | pmid:3911474 |
Korting HC | [Urethritis in the male, diagnosis and therapy]. | 1985 | Ther Umsch | pmid:2935962 |
Münnich D et al. | Observations on micro-encapsulated erythromycin (Eryc capsule) in the treatment of various infections of adults. | 1988 | Ther Hung | pmid:3249998 |
Ferencz A et al. | Use of Eryc capsule in adult patients. | 1989 | Ther Hung | pmid:2686082 |
RUBANYI P and KOS R | ACTUAL PROBLEMS OF ANTIBIOTIC TREATMENT IN SURGICAL PRACTICE. | 1963 | Ther Hung | pmid:14133128 |
Adám A and Kuberka Z | Use of a new erythromycin product--eryc--in the treatment of the lower respiratory tract infections. | 1990 | Ther Hung | pmid:2094053 |
FIEGEL G | [The place of erythromycin among the antibiotics]. | 1957 | Ther Ggw | pmid:13422363 |
ILKER HG | [Not Available]. | 1957 | Ther Ggw | pmid:13422370 |
Petzoldt D | [Current diagnosis and therapy of acquired syphilis]. | 1973 | Ther Ggw | pmid:4708581 |
Wadhwa NK et al. | Interaction between erythromycin and cyclosporine in a kidney and pancreas allograft recipient. | 1987 | Ther Drug Monit | pmid:3554626 |
Buiter HJ et al. | Erythromycin precipitation in vena femoralis: investigation of crystals found in postmortem material of an intensive care unit patient. | 2008 | Ther Drug Monit | pmid:18223476 |