erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Tooth Fractures D014082 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Onychomycosis D014009 2 associated lipids
Thyroid Crisis D013958 1 associated lipids
Thromboembolism D013923 6 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Tachycardia D013610 7 associated lipids
Syphilis, Latent D013592 4 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Syphilis D013587 6 associated lipids
Synovitis D013585 15 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Streptococcal Infections D013290 4 associated lipids
Stomatitis D013280 14 associated lipids
Stomach Diseases D013272 7 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Sporotrichosis D013174 3 associated lipids
Splenomegaly D013163 4 associated lipids
Splenic Infarction D013159 1 associated lipids
Skin Ulcer D012883 6 associated lipids
Skin Neoplasms D012878 12 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Sinusitis D012852 9 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Sialadenitis D012793 1 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Seizures D012640 87 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Scarlet Fever D012541 1 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Salpingitis D012488 2 associated lipids
Rubella D012409 2 associated lipids
Rosacea D012393 13 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Rickettsia Infections D012282 5 associated lipids
Rhinitis D012220 10 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Relapsing Fever D012061 3 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Radiodermatitis D011855 3 associated lipids
Quadriplegia D011782 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Stieler AL et al. Macrolide-induced hyperthermia in foals: Role of impaired sweat responses. 2016 Equine Vet. J. pmid:26174202
Kumpfmüller J et al. Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis. 2016 Appl. Microbiol. Biotechnol. pmid:26432460
Deloose E et al. Higher plasma motilin levels in obese patients decrease after Roux-en-Y gastric bypass surgery and regulate hunger. 2016 Gut pmid:25986945
Mombelli A et al. Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci. 2016 J. Periodontol. pmid:26654350
Ulanovsky I et al. Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. 2016 Isr. Med. Assoc. J. pmid:28471562
Sagkan-Ozturk A et al. Prokinetics stimulate the increase of ghrelin in mice. 2016 Bratisl Lek Listy pmid:28127970
Talebi M et al. Determination of Characteristics of Erythromycin Resistant Streptococcus pneumoniae with Preferred PCV Usage in Iran. 2016 PLoS ONE pmid:28033345
Ray D et al. Molecular characterization and evaluation of the emerging antibiotic-resistant Streptococcus pyogenes from eastern India. 2016 BMC Infect. Dis. pmid:27955635
Ma Y et al. Antimicrobial activity of topical agents against Propionibacterium acnes: an in vitro study of clinical isolates from a hospital in Shanghai, China. 2016 Front Med pmid:27896620
Aslantaş Ö and Demir C Investigation of the antibiotic resistance and biofilm-forming ability of Staphylococcus aureus from subclinical bovine mastitis cases. 2016 J. Dairy Sci. pmid:27592437
Budha NR et al. Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation. 2016 Clin Pharmacokinet pmid:27225997
Wan TW et al. Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256's Spread, and Evolution of Russia ST8-IV. 2016 PLoS ONE pmid:27741255
Hadjipanayis A et al. Nasopharyngeal Pneumococcal Carriage among Healthy Children in Cyprus Post Widespread Simultaneous Implementation of PCV10 and PCV13 Vaccines. 2016 PLoS ONE pmid:27706247
Krishnamoorthy G et al. Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane. 2016 Antimicrob. Agents Chemother. pmid:27697764
Li M et al. Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China. 2016 Int J Mol Sci pmid:27669217
Murchison L et al. Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. 2016 Pediatr. Surg. Int. pmid:27655365
Dzyubak E and Yap MN The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling. 2016 Antimicrob. Agents Chemother. pmid:27645242
Abreu AC et al. Combinatorial approaches with selected phytochemicals to increase antibiotic efficacy against Staphylococcus aureus biofilms. 2016 Biofouling pmid:27643487
Jurado-Tarifa E et al. Genetic diversity and antimicrobial resistance of Campylobacter and Salmonella strains isolated from decoys and raptors. 2016 Comp. Immunol. Microbiol. Infect. Dis. pmid:27638115
Hu Z et al. Short-term performance of enhanced biological phosphorus removal (EBPR) system exposed to erythromycin (ERY) and oxytetracycline (OTC). 2016 Bioresour. Technol. pmid:27631889
Benamrouche N et al. Microbiological and molecular characterization of Corynebacterium diphtheriae isolated in Algeria between 1992 and 2015. 2016 Clin. Microbiol. Infect. pmid:27585941
Kang CH and So JS Antibiotic and heavy metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea, Korea. 2016 Mar. Pollut. Bull. pmid:27555484
Wu L et al. Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. 2016 PLoS ONE pmid:27447724
Kwon JW Environmental impact assessment of veterinary drug on fish aquaculture for food safety. 2016 Drug Test Anal pmid:27443211
Aslan Bayhan S et al. Effects of topical acne treatment on the ocular surface in patients with acne vulgaris. 2016 Cont Lens Anterior Eye pmid:27422575
Li X et al. Effects of Total Alkaloids of Sophora alopecuroides on Biofilm Formation in Staphylococcus epidermidis. 2016 Biomed Res Int pmid:27413745
Ababou A and Koronakis V Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. 2016 PLoS ONE pmid:27403665
Yuan QB et al. Reductions of bacterial antibiotic resistance through five biological treatment processes treated municipal wastewater. 2016 Environ Sci Pollut Res Int pmid:27384166
Karlsson E et al. Clonality of erythromycin resistance in Francisella tularensis. 2016 J. Antimicrob. Chemother. pmid:27334667
Changchien CH et al. Antibiotic susceptibility and genomic variations in Staphylococcus aureus associated with Skin and Soft Tissue Infection (SSTI) disease groups. 2016 BMC Infect. Dis. pmid:27287530
Waiser MJ et al. Effects of erythromycin, trimethoprim and clindamycin on attached microbial communities from an effluent dominated prairie stream. 2016 Ecotoxicol. Environ. Saf. pmid:27261880
Karničar K et al. Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea. 2016 Microb. Cell Fact. pmid:27255285
Ghosh S and Banerjee M Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus. 2016 Indian J. Med. Res. pmid:27241651
Pignatello R et al. Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. 2016 Eur J Med Chem pmid:27236014
Mushtaq A et al. Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva. 2016 Antimicrob. Agents Chemother. pmid:27216060
Hong M et al. Impacts of proline on the central metabolism of an industrial erythromycin-producing strain Saccharopolyspora erythraea via (13)C labeling experiments. 2016 J. Biotechnol. pmid:27215341
Stacevičienė I et al. Antibiotic resistance of Streptococcus pneumoniae, isolated from nasopharynx of preschool children with acute respiratory tract infection in Lithuania. 2016 BMC Infect. Dis. pmid:27206423
Tatiya-Aphiradee N et al. In vivo antibacterial activity of Garcinia mangostana pericarp extract against methicillin-resistant Staphylococcus aureus in a mouse superficial skin infection model. 2016 Pharm Biol pmid:27180784
Trac MH et al. Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. 2016 CMAJ pmid:26903359
He M et al. Mechanism of synergy between SIPI-8294 and β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. 2016 Lett. Appl. Microbiol. pmid:27173151
Patel MB et al. Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. 2016 Bioorg. Med. Chem. pmid:27166575
Taylor SJ et al. A randomised controlled feasibility and proof-of-concept trial in delayed gastric emptying when metoclopramide fails: We should revisit nasointestinal feeding versus dual prokinetic treatment: Achieving goal nutrition in critical illness and delayed gastric emptying: Trial of nasointestinal feeding versus nasogastric feeding plus prokinetics. 2016 Clin Nutr ESPEN pmid:28531392
Guo Q et al. Controlling the feed rate of propanol to optimize erythromycin fermentation by on-line capacitance and oxygen uptake rate measurement. 2016 Bioprocess Biosyst Eng pmid:26615414
Zhang A et al. Molecular subtyping and erythromycin resistance of Campylobacter in China. 2016 J. Appl. Microbiol. pmid:26999516
Mukai S et al. Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. 2016 Int. J. Oncol. pmid:26718641
Sousa M et al. Genetic Diversity and Antibiotic Resistance Among Coagulase-Negative Staphylococci Recovered from Birds of Prey in Portugal. 2016 Microb. Drug Resist. pmid:26990729
Morroni G et al. Enterococcus faecium ST17 from Coastal Marine Sediment Carrying Transferable Multidrug Resistance Plasmids. 2016 Microb. Drug Resist. pmid:26982016
Lenart-Boroń A et al. Phenotypic and Molecular Antibiotic Resistance Determination of Airborne Coagulase Negative Staphylococcus spp. Strains from Healthcare Facilities in Southern Poland. 2016 Microb. Drug Resist. pmid:26978225
Li X et al. Macrolides use and the risk of sudden cardiac death. 2016 Expert Rev Anti Infect Ther pmid:27086751
Diawara I et al. Phenotypic and genotypic characterization of Streptococcus pneumoniae resistant to macrolide in Casablanca, Morocco. 2016 Infect. Genet. Evol. pmid:26961592
Barros RR et al. Polyclonal spread of Streptococcus agalactiae resistant to clindamycin among pregnant women in Brazil. 2016 J. Antimicrob. Chemother. pmid:27029847
Sierra-Arguello YM et al. Fluoroquinolone and macrolide resistance in Campylobacter jejuni isolated from broiler slaughterhouses in southern Brazil. 2016 Avian Pathol. pmid:26925976
Molina-Manso D et al. Effect of different agents with potential antibiofilm activity on antimicrobial susceptibility of biofilms formed by Staphylococcus spp. isolated from implant-related infections. 2016 J. Antibiot. pmid:26905757
Meng HL et al. Construction of polyketide overproducing Escherichia coli strains via synthetic antisense RNAs based on in silico fluxome analysis and comparative transcriptome analysis. 2016 Biotechnol J pmid:26709503
Madmanang S et al. Constituents of Fagraea fragrans with Antimycobacterial Activity in Combination with Erythromycin. 2016 J. Nat. Prod. pmid:26905094
Aydin S et al. Assessment of anaerobic bacterial diversity and its effects on anaerobic system stability and the occurrence of antibiotic resistance genes. 2016 Bioresour. Technol. pmid:26897411
Baek YS et al. Antimicrobial resistance of Staphylococcus aureus isolated from skin infections and its implications in various clinical conditions in Korea. 2016 Int. J. Dermatol. pmid:26892888
Chua SL et al. Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms. 2016 Nat Commun pmid:26892159
Liu H et al. [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. 2016 Zhonghua Er Ke Za Zhi pmid:26875461
Poliquin V et al. Preparedness for Implementing Change in Neonatal Ocular Prophylaxis Policies. 2016 J Obstet Gynaecol Can pmid:26872748
Bouvet L et al. Ultrasound Assessment of the Prokinetic Effect of Erythromycin in Trauma Patients with a Full Stomach: A Case Series. 2016 Anesth. Analg. pmid:26859878
Moltó-García B et al. Molecular characterization and antimicrobial susceptibility of hemolytic Streptococcus agalactiae from post-menopausal women. 2016 Maturitas pmid:26857873
Sari E et al. Fabrication of surface plasmon resonance nanosensor for the selective determination of erythromycin via molecular imprinted nanoparticles. 2016 Talanta pmid:26838449
Magnussen MD et al. Antibacterial resistance in Streptococcus pyogenes (GAS) from healthy carriers and tonsillitis patients and association with antibacterial sale in the Faroe Islands. 2016 APMIS pmid:26833774
Gupta P et al. Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. 2016 Nat. Chem. Biol. pmid:26727240
Dréno B Bacteriological resistance in acne: A call to action. 2016 Eur J Dermatol pmid:26711531
Parhizgari N et al. High frequency of multidrug-resistant Staphylococcus aureus with SCCmec type III and Spa types t037 and t631 isolated from burn patients in southwest of Iran. 2016 APMIS pmid:26709106
Chuang MC et al. Diffuse panbronchiolitis-The response and recurrence after erythromycin therapy. 2016 J. Formos. Med. Assoc. pmid:26705139
Broad J et al. RQ-00201894: A motilin receptor agonist causing long-lasting facilitation of human gastric cholinergically-mediated contractions. 2016 J. Pharmacol. Sci. pmid:26685754
Sayed Ahmed WA et al. Maternal serum interleukin-6 in the management of patients with preterm premature rupture of membranes. 2016 J. Matern. Fetal. Neonatal. Med. pmid:26669630
Caspi M et al. A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. 2016 J. Mol. Med. pmid:26620677
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Li J et al. Rhubarb to Facilitate Placement of Nasojejunal Feeding Tubes in Patients in the Intensive Care Unit. 2016 Nutr Clin Pract pmid:26459161
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Feuillolay C et al. A Myrtus communis extract enriched in myrtucummulones and ursolic acid reduces resistance of Propionibacterium acnes biofilms to antibiotics used in acne vulgaris. 2016 Phytomedicine pmid:26969384
Ohbatake Y et al. Elevated alpha1-acid glycoprotein in gastric cancer patients inhibits the anticancer effects of paclitaxel, effects restored by co-administration of erythromycin. 2016 Clin. Exp. Med. pmid:26359244
Brunel R and Charpentier X Trans-translation is essential in the human pathogen Legionella pneumophila. 2016 Sci Rep pmid:27892503
Naik KM and Nandibewoor ST Investigation into the interaction of methylparaben and erythromycin with human serum albumin using multispectroscopic methods. 2016 Luminescence pmid:26239839
Yuan SF et al. Levels of six antibiotics used in China estimated by means of wastewater-based epidemiology. 2016 Water Sci. Technol. pmid:26901719
Jakkidi M et al. An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction. 2017 BMJ Case Rep pmid:28768672
Jeong S et al. Combined photodynamic and antibiotic therapy for skin disorder via lipase-sensitive liposomes with enhanced antimicrobial performance. 2017 Biomaterials pmid:28697465
Lamari F et al. Assessment of the correlation among antibiotic resistance, adherence to abiotic and biotic surfaces, invasion and cytotoxicity of Pseudomonas aeruginosa isolated from diseased gilthead sea bream. 2017 Colloids Surf B Biointerfaces pmid:28697438
Kasetty G et al. The Nonantibiotic Macrolide EM703 Improves Survival in a Model of Quinolone-Treated Pseudomonas aeruginosa Airway Infection. 2017 Antimicrob. Agents Chemother. pmid:28652240
Mingmongkolchai S and Panbangred W In vitro evaluation of candidate Bacillus spp. for animal feed. 2017 J. Gen. Appl. Microbiol. pmid:28331163
Attaran B et al. Effect of biofilm formation by clinical isolates of on the efflux-mediated resistance to commonly used antibiotics. 2017 World J. Gastroenterol. pmid:28275296
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Waites KB et al. In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. 2017 Antimicrob. Agents Chemother. pmid:27855075
Zhang W et al. Isolation and characterization of a high-efficiency erythromycin A-degrading Ochrobactrum sp. strain. 2017 Mar. Pollut. Bull. pmid:27863881
Li B et al. Antimicrobial Resistance of Campylobacter Species Isolated from Broilers in Live Bird Markets in Shanghai, China. 2017 Foodborne Pathog. Dis. pmid:27854542
Dolberg AM and Reichl S Activity of Multidrug Resistance-Associated Proteins 1-5 (MRP1-5) in the RPMI 2650 Cell Line and Explants of Human Nasal Turbinate. 2017 Mol. Pharm. pmid:28291371
Massip C et al. Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. 2017 J. Antimicrob. Chemother. pmid:28137939
García-Iglesias P et al. Management of non variceal upper gastrointestinal bleeding: position statement of the Catalan Society of Gastroenterology. 2017 Gastroenterol Hepatol pmid:28109636
Argemi X et al. VISLISI trial, a prospective clinical study allowing identification of a new metalloprotease and putative virulence factor from Staphylococcus lugdunensis. 2017 Clin. Microbiol. Infect. pmid:28017792
Yi M et al. Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis. 2017 Arch. Biochem. Biophys. pmid:28347661
Zheng PX et al. Highly prevalent emmSTG840.0 and emmSTC839.0 types of erythromycin non-susceptible group G Streptococcus isolated from bacteremia in southern Taiwan. 2017 J Microbiol Immunol Infect pmid:28711431
Abreu AC et al. Looking to nature for a new concept in antimicrobial treatments: isoflavonoids from Cytisus striatus as antibiotic adjuvants against MRSA. 2017 Sci Rep pmid:28630440
Feng L et al. Removal of antibiotics during the anaerobic digestion of pig manure. 2017 Sci. Total Environ. pmid:28628813
Tay JH et al. Regiodivergent Glycosylations of 6-Deoxy-erythronolide B and Oleandomycin-Derived Macrolactones Enabled by Chiral Acid Catalysis. 2017 J. Am. Chem. Soc. pmid:28627172