erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Respiratory Insufficiency D012131 10 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Ischemia D007511 18 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Thromboembolism D013923 6 associated lipids
Periodontitis D010518 22 associated lipids
Dermatitis D003872 30 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Vomiting D014839 21 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Streptococcal Infections D013290 4 associated lipids
Otitis D010031 5 associated lipids
Cholelithiasis D002769 16 associated lipids
Fever D005334 35 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Pneumonia D011014 10 associated lipids
Conjunctivitis D003231 7 associated lipids
Syphilis D013587 6 associated lipids
Chorioamnionitis D002821 5 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Hearing Disorders D006311 10 associated lipids
Duodenitis D004382 4 associated lipids
Death, Sudden D003645 12 associated lipids
Cardiomegaly D006332 31 associated lipids
Tachycardia D013610 7 associated lipids
Common Cold D003139 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Foot Diseases D005534 4 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Neutropenia D009503 15 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Urticaria D014581 13 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
HIV Seropositivity D006679 15 associated lipids
Uveitis D014605 14 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Padovan J et al. Investigating the barriers to bioavailability of macrolide antibiotics in the rat. 2012 Eur J Drug Metab Pharmacokinet pmid:22113743
Walkey AJ and Wiener RS Macrolide antibiotics and survival in patients with acute lung injury. 2012 Chest pmid:22116799
Sugimoto T et al. Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. 2012 Bioorg. Med. Chem. Lett. pmid:22858102
Zou MX et al. Antimicrobial resistance and molecular epidemiological characteristics of clinical isolates of Staphylococcus aureus in Changsha area. 2012 Chin. Med. J. pmid:22882850
Dekio I Follicular spicules associated with Propionibacterium acnes with response to erythromycin: Lack of evidence for the species? 2012 J. Dermatol. pmid:22224953
Gant CM et al. Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. 2012 Antimicrob. Agents Chemother. pmid:22751535
Kim J et al. Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea. 2012 J. Microbiol. pmid:22752920
Arakawa K et al. The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. 2012 Chembiochem pmid:22761035
Licona-Cassani C et al. Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. 2012 Antonie Van Leeuwenhoek pmid:22847261
Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. 2012 Prescrire Int pmid:22852287
Kim EY et al. The effectiveness of erythromycin in reducing stent-related tissue hyperplasia: an experimental study with a rat esophageal model. 2012 Acta Radiol pmid:22855416
Cetin M et al. Clarithromycin-Induced Long QT Syndrome: A Case Report. 2012 Case Rep Med pmid:22489247
Perry DM et al. Identification and characterization of protein phosphatase 2C activation by ceramide. 2012 J. Lipid Res. pmid:22615346
Geddes BA and Oresnik IJ Genetic characterization of a complex locus necessary for the transport and catabolism of erythritol, adonitol and L-arabitol in Sinorhizobium meliloti. 2012 Microbiology (Reading, Engl.) pmid:22609752
Bidet P et al. Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. 2012 Eur. J. Clin. Microbiol. Infect. Dis. pmid:22610663
Liu X et al. [The effect of biyuanshu oral liquid on the formation of Pseudomonas aeruginosa biofilms in vitro]. 2012 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:23156807
Chen X et al. Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides. 2012 Bioorg. Med. Chem. Lett. pmid:23122862
Tolosa L et al. Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. 2012 Toxicol. Sci. pmid:22331495
Ocular prophylaxis for gonococcal ophthalmia neonatorum: reaffirmation recommendation statement. 2012 Am Fam Physician pmid:22335221
Jordan PA and Miller SJ An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer. 2012 Angew. Chem. Int. Ed. Engl. pmid:22319027
Henningsen E and Bygum A Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. 2011 Sep-Oct Pediatr Dermatol pmid:21895758
Ezhova NM et al. [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. 2011 Nov-Dec Prikl. Biokhim. Mikrobiol. pmid:22288199
Zhang W et al. Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. 2011 Curr. Microbiol. pmid:20924584
Hewer RC et al. PKA and Epac synergistically inhibit smooth muscle cell proliferation. 2011 J. Mol. Cell. Cardiol. pmid:20971121
Fessler AT et al. Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. 2011 Antimicrob. Agents Chemother. pmid:20876371
Ogungbenro K et al. A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients. 2011 Pharm. Res. pmid:20949310
Nakashima R et al. Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. 2011 Nature pmid:22121023
Abarzúa F et al. [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. 2011 Rev Chilena Infectol pmid:22052397
Song W et al. Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. 2011 Int J Nanomedicine pmid:22228990
Hiller NL et al. Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. 2011 PLoS ONE pmid:22205975
Tachecí I et al. Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. 2011 Neuro Endocrinol. Lett. pmid:22167215
Watanabe I et al. Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block. 2011 Int Heart J pmid:22188715
Saderi H et al. Phenotypic and genotypic study of macrolide, lincosamide and streptogramin B (MLSB) resistance in clinical isolates of Staphylococcus aureus in Tehran, Iran. 2011 Med. Sci. Monit. pmid:21278685
Zhang Q et al. Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. 2011 Lett. Appl. Microbiol. pmid:21175699
Lam HS and Ng PC Use of prokinetics in the preterm infant. 2011 Curr. Opin. Pediatr. pmid:21178622
Ma S et al. Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. 2011 Eur J Med Chem pmid:21159410
Mak PJ et al. Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. 2011 J. Am. Chem. Soc. pmid:21207936
Ren GW et al. Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. 2011 Foodborne Pathog. Dis. pmid:21166562
Srinivasan U et al. Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae. 2011 Microb. Drug Resist. pmid:21166574
Khan NW et al. Antimicrobial activity of erythromycin and clarithromycin against clinical isolates of Escherichia coli, Staphylococcus aureus, Klebsiella and Proteus by disc diffusion method. 2011 Pak J Pharm Sci pmid:21190914
Wu J et al. Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. 2011 Appl. Environ. Microbiol. pmid:21841022
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Wunder DB et al. Sorption of antibiotics to biofilm. 2011 Water Res. pmid:21334040
Sonnevend Á et al. Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. 2011 Scand. J. Infect. Dis. pmid:21905953
Jessick AM et al. Optimization of analytical methods to improve detection of erythromycin from water and sediment. 2011 J Environ Sci Health B pmid:21877980
Lee CY et al. Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. 2011 Implant Dent pmid:21881516
Tazi A et al. Invasive group B streptococcal infections in adults, France (2007-2010). 2011 Clin. Microbiol. Infect. pmid:21883671
Fenoll A et al. Increase in serotype 19A prevalence and amoxicillin non-susceptibility among paediatric Streptococcus pneumoniae isolates from middle ear fluid in a passive laboratory-based surveillance in Spain, 1997-2009. 2011 BMC Infect. Dis. pmid:21910891
Szary NM et al. Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. 2011 Scand. J. Gastroenterol. pmid:21561232
Wei Z and Wang J Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. 2011 Anal. Chim. Acta pmid:21565301
Ren W and Markel DC Emerging ideas: can erythromycin reduce the risk of aseptic loosening? 2011 Clin. Orthop. Relat. Res. pmid:21584820
Torra S et al. Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). 2011 Int J Obes (Lond) pmid:20938444
Li MJ et al. High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. 2011 Analyst pmid:20944848
Andini N and Nash KA Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. 2011 FEMS Microbiol. Lett. pmid:21718348
Li AP and Doshi U Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. 2011 Drug Metab Lett pmid:21722087
Imperi M et al. Invasive neonatal GBS infections from an area-based surveillance study in Italy. 2011 Clin. Microbiol. Infect. pmid:21722258
Wan G et al. Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. 2011 Cell. Signal. pmid:21723942
Kalmokoff M et al. Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. 2011 J. Appl. Microbiol. pmid:21395944
Haenni M et al. ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis. 2011 Vet. J. pmid:20667752
Miyashita N et al. Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. 2011 J. Infect. Chemother. pmid:20676912
Chen I et al. Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. 2011 J. Clin. Microbiol. pmid:21068284
You L et al. Dynamic multi-component covalent assembly for the reversible binding of secondary alcohols and chirality sensing. 2011 Nat Chem pmid:22109274
Bilk S et al. Antimicrobial susceptibilities and occurrence of resistance genes in bovine Helcococcus ovis isolates. 2011 Vet. Microbiol. pmid:21131144
Zou X et al. An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. 2011 Bioresour. Technol. pmid:21134745
Palmieri C et al. Different genetic elements carrying the tet(W) gene in two human clinical isolates of Streptococcus suis. 2011 Antimicrob. Agents Chemother. pmid:21115784
Guo L et al. Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. 2011 Toxicol. Sci. pmid:21693436
Modali SD and Zgurskaya HI The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. 2011 Mol. Microbiol. pmid:21696464
Jorgensen JH et al. Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. 2011 J. Clin. Microbiol. pmid:21697321
Wenzel F et al. Alterations of serum erythropoietin and thrombopoietin levels in patients undergoing Coronary Artery Bypass Grafting (CABG). 2011 Clin. Hemorheol. Microcirc. pmid:22214710
Mansi Y et al. Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants. 2011 Neonatology pmid:21701222
Amarir-Bouhram J et al. Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. 2011 PLoS ONE pmid:22194937
Ng PC Erythromycin as a prokinetic agent in newborns--useful or doubtful. Commentary on Y. Mansi et al.: Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants (Neonatology 2011;100:290-294). 2011 Neonatology pmid:21701224
Sarig H et al. Functional studies of cochleate assemblies of an oligo-acyl-lysyl with lipid mixtures for combating bacterial multidrug resistance. 2011 FASEB J. pmid:21676947
Shingate BB et al. Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. 2011 Eur J Med Chem pmid:21664730
Buendia J et al. Preparation of diastereomerically pure dilignol model compounds. 2011 Chemistry pmid:22076640
Hoa PT et al. Antibiotic contamination and occurrence of antibiotic-resistant bacteria in aquatic environments of northern Vietnam. 2011 Sci. Total Environ. pmid:21669325
Maragno AL et al. ISG15 modulates development of the erythroid lineage. 2011 PLoS ONE pmid:22022510
Joao EC et al. Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile. 2011 Scand. J. Infect. Dis. pmid:21671824
Kreft A et al. JAK2-V617F-mutated myeloproliferative neoplasms reveal different allele burden within hematopoietic cell lineages: a microdissection study of bone marrow trephine biopsies. 2011 Virchows Arch. pmid:22006129
Fry DE Colon preparation and surgical site infection. 2011 Am. J. Surg. pmid:21429471
de Morais e Silva FA et al. Rosacea fulminans in pregnancy with ocular perforation. 2011 J Dtsch Dermatol Ges pmid:21366860
Boghigian BA et al. Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. 2011 Biotechnol. Bioeng. pmid:21337322
Kataoka M et al. Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. 2011 Eur J Pharm Sci pmid:21963456
Hernández y Ballinas A et al. [Comparison of maternal and perinatal outcomes in the conservative treatment preterm premature membrane rupture between the use of erythromycin and clindamycin]. 2011 Ginecol Obstet Mex pmid:21966834
Gupta R et al. A 14-year-old with rectal bleeding and abdominal pain. 2011 J. Pediatr. Gastroenterol. Nutr. pmid:21970991
Heath AP et al. An algorithm for efficient identification of branched metabolic pathways. 2011 J. Comput. Biol. pmid:21999288
Ho PL et al. Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. 2011 Diagn. Microbiol. Infect. Dis. pmid:22000087
Gozalbes R et al. QSAR-based permeability model for drug-like compounds. 2011 Bioorg. Med. Chem. pmid:21458999
Boleda MA et al. Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments. 2011 Environ. Pollut. pmid:21459501
Zhang Z et al. Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21498135
Del Grosso M et al. Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. 2011 Antimicrob. Agents Chemother. pmid:21502613
Loreto ES et al. In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. 2011 Antimicrob. Agents Chemother. pmid:21537028
Nakamura PA et al. Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. 2011 Mem. Inst. Oswaldo Cruz pmid:21537668
Shaala LA et al. Brominated arginine-derived alkaloids from the red sea sponge Suberea mollis. 2011 J. Nat. Prod. pmid:21542602
Zhao DL et al. Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas. 2011 Microb. Cell Fact. pmid:21542941
Gannon M et al. Clinical inquiries. Which oral antibiotics are best for acne? 2011 J Fam Pract pmid:21544278
Chia HY et al. Follicular spicules associated with Propionibacterium acnes in response to erythromycin. 2011 J. Dermatol. pmid:21544949
Nguyen TT et al. A food-grade system for inducible gene expression in Lactobacillus plantarum using an alanine racemase-encoding selection marker. 2011 J. Agric. Food Chem. pmid:21504147
Chen HX et al. [Compound erythromycin sustained release preparation and its in vitro release]. 2011 Yao Xue Xue Bao pmid:22260035
Wei Z et al. [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. 2011 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22260078