erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chen D et al. | Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. | 2014 | PLoS ONE | pmid:25250723 |
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Goni BW et al. | Diphtheria in a 7-year-old child in north-eastern Nigeria - management in a resource-poor setting. | 2014 | Trop Doct | pmid:24249028 |
Sadeghi J and Mansouri S | Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman). | 2014 | APMIS | pmid:24033803 |
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Sanamrad A et al. | Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25056965 |
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Florindo C et al. | Epidemiological surveillance of colonising group B Streptococcus epidemiology in the Lisbon and Tagus Valley regions, Portugal (2005 to 2012): emergence of a new epidemic type IV/clonal complex 17 clone. | 2014 | Euro Surveill. | pmid:24957747 |
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Blattner C et al. | A case of bacillary angiomatosis in a patient with pancreatic adenocarcinoma. | 2014 | J. Cutan. Pathol. | pmid:24588271 |
Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. | 2014 | Antimicrob. Agents Chemother. | pmid:24449773 |
Pierson RC et al. | A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. | 2014 | Obstet Gynecol | pmid:25162251 |
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Sugamata R et al. | Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. | 2014 | J. Antibiot. | pmid:24496145 |
Silva CM et al. | Population dynamics and antimicrobial susceptibility of Aeromonas spp. along a salinity gradient in an urban estuary in Northeastern Brazil. | 2014 | Mar. Pollut. Bull. | pmid:25455376 |
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Fröhlicher S et al. | Serotype distribution and antimicrobial susceptibility of group B streptococci in pregnant women: results from a Swiss tertiary centre. | 2014 | Swiss Med Wkly | pmid:24652673 |
ŽemliÄková H et al. | [Resistance monitoring working group: resistance to erythromycin, ciprofloxacin, and tetracycline in human isolates of Campylobacter spp. in the Czech Republic tested by the EUCAST standard method]. | 2014 | Epidemiol Mikrobiol Imunol | pmid:25412481 |
Cai HL et al. | Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24424301 |
Arêas GP et al. | Antimicrobial susceptibility patterns, emm type distribution and genetic diversity of Streptococcus pyogenes recovered in Brazil. | 2014 | Mem. Inst. Oswaldo Cruz | pmid:25410998 |
Khannous L et al. | Isolation of a novel amylase and lipase-producing Pseudomonas luteola strain: study of amylase production conditions. | 2014 | Lipids Health Dis | pmid:24405763 |
Wang J et al. | [Drug susceptibility and homologous analysis on Corynebacterium striatum strains isolated from inpatients]. | 2014 | Zhonghua Yi Xue Za Zhi | pmid:25410920 |
Fan L and Xu J | [Application progress of macrolide sustained therapy for bronchiectasis]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24694975 |
Wu H et al. | Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea. | 2014 | Microb. Cell Fact. | pmid:25391994 |
Leirós M et al. | Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. | 2014 | ACS Chem Neurosci | pmid:24219236 |
Sugawara E and Nikaido H | Properties of AdeABC and AdeIJK efflux systems of Acinetobacter baumannii compared with those of the AcrAB-TolC system of Escherichia coli. | 2014 | Antimicrob. Agents Chemother. | pmid:25246403 |
Corona PS et al. | Case report: first report of a prosthetic joint infection caused by Facklamia hominis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25245196 |
Ziupa D et al. | Pronounced effects of HERG-blockers E-4031 and erythromycin on APD, spatial APD dispersion and triangulation in transgenic long-QT type 1 rabbits. | 2014 | PLoS ONE | pmid:25244401 |
Westerhof J et al. | Completion rate of small bowel capsule endoscopy is higher after erythromycin compared to domperidone. | 2014 | BMC Gastroenterol | pmid:25234278 |
Badri T et al. | [Erythrasma: study of 16 cases]. | 2014 | Tunis Med | pmid:25224418 |
Dörries K et al. | Impact of antibiotics with various target sites on the metabolome of Staphylococcus aureus. | 2014 | Antimicrob. Agents Chemother. | pmid:25224006 |
Labbeiki G et al. | Enhanced oxygen transfer rate and bioprocess yield by using magnetite nanoparticles in fermentation media of erythromycin. | 2014 | Daru | pmid:25223458 |
Bharucha AE et al. | A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography. | 2014 | Eur J Radiol | pmid:25217123 |
Johnson SR et al. | In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins. | 2014 | Antimicrob. Agents Chemother. | pmid:25199775 |
Kara M et al. | Expression changes of antioxidant, apoptotic, anti-apoptotic genes and miR-15b-34a-21-98 in over tissue by using erythromycin, quinacrine and tetracycline in non-surgical sterilization. | 2014 | Mol. Biol. Rep. | pmid:25195052 |
Shera IA et al. | Unusual case of Hashimoto's encephalopathy and pseudo-obstruction in a patient with undiagnosed hypothyroidism: a case report. | 2014 | J Med Case Rep | pmid:25194644 |
Usui M et al. | Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. | 2014 | Vet. Rec. | pmid:25163817 |
Kemp MW et al. | Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. | 2014 | Am. J. Obstet. Gynecol. | pmid:24589547 |
Zhang Y et al. | [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. | 2014 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:24721407 |
Hoover WD et al. | Topical antibiotic monotherapy prescribing practices in acne vulgaris. | 2014 | J Dermatolog Treat | pmid:24171409 |
Bos JC et al. | Antimicrobial susceptibility of Streptococcus pneumoniae in adult patients with pneumococcal pneumonia in an urban hospital in Mozambique. | 2014 | BMC Res Notes | pmid:24568650 |
Feng Y et al. | Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. | 2014 | Foodborne Pathog. Dis. | pmid:25054781 |
Flamm RK et al. | Antimicrobial activity of ceftaroline tested against drug-resistant subsets of Streptococcus pneumoniae from U.S. medical centers. | 2014 | Antimicrob. Agents Chemother. | pmid:24514082 |
Sahu AK et al. | Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. | 2014 | Biomed Res Int | pmid:25045692 |
Arakawa K | Genetic and biochemical analysis of the antibiotic biosynthetic gene clusters on the Streptomyces linear plasmid. | 2014 | Biosci. Biotechnol. Biochem. | pmid:25036669 |
Pasquaroli S et al. | Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to human Enterococcus faecalis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25017384 |
Yeung SW et al. | Comparison of the effect of penicillins versus erythromycin in preventing neonatal group B streptococcus infection in active carriers following preterm prelabor rupture of membranes. | 2014 | Taiwan J Obstet Gynecol | pmid:25017269 |
Nuyujukian DS et al. | Medication use and multiple myeloma risk in Los Angeles County. | 2014 | Cancer Causes Control | pmid:24981100 |
Iatrou EI et al. | Consumption-based approach for predicting environmental risk in Greece due to the presence of antimicrobials in domestic wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24981036 |
Ramos V et al. | [Mobile genetic elements associated with erythromycin-resistant isolates of Streptococcus pneumoniae in Colombia]. | 2014 | Biomedica | pmid:24968052 |
Moore KT et al. | An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function. | 2014 | J Clin Pharmacol | pmid:24964176 |
Montilla A et al. | Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate. | 2014 | Antimicrob. Agents Chemother. | pmid:24957835 |
Komiya K et al. | Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. | 2014 | Int. J. Antimicrob. Agents | pmid:24948577 |
Arana DM et al. | First clinical isolate in Europe of clindamycin-resistant group B Streptococcus mediated by the lnu(B) gene. | 2014 | Rev Esp Quimioter | pmid:24940891 |
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Liu J et al. | Tissue distribution, bioconcentration, metabolism, and effects of erythromycin in crucian carp (Carassius auratus). | 2014 | Sci. Total Environ. | pmid:24911771 |
Piccinelli G et al. | In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. | 2014 | Antimicrob. Agents Chemother. | pmid:24379197 |
Ramos FL and Criner GJ | Use of long-term macrolide therapy in chronic obstructive pulmonary disease. | 2014 | Curr Opin Pulm Med | pmid:24378875 |
Jing YR et al. | The synthesis of novel taxoids for oral administration. | 2014 | Bioorg. Med. Chem. | pmid:24332858 |
Sakamoto N et al. | Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. | 2014 | Intern. Med. | pmid:24739609 |
Dechert-Schmitt AM et al. | Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. | 2014 | Nat Prod Rep | pmid:24514754 |
Szemraj M et al. | Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. | 2014 | Microb. Drug Resist. | pmid:24735183 |
Moreno LZ et al. | Characterization of antibiotic resistance in Listeria spp. isolated from slaughterhouse environments, pork and human infections. | 2014 | J Infect Dev Ctries | pmid:24727506 |
Geng Q et al. | Molecular characterization and antimicrobial susceptibility of Streptococcus pneumoniae isolated from children hospitalized with respiratory infections in Suzhou, China. | 2014 | PLoS ONE | pmid:24710108 |
Hellmann-Regen J et al. | Do tetracyclines and erythromycin exert anti-acne effects by inhibition of P450-mediated degradation of retinoic acid? | 2014 | Exp. Dermatol. | pmid:24690039 |
Xu J et al. | Phenotypic and genotypic antimicrobial resistance traits of foodborne Staphylococcus aureus isolates from Shanghai. | 2014 | J. Food Sci. | pmid:24689704 |
Wang D et al. | Structural and environmental features of novel mdfA variant and mdfA genes in recombinant regions of Escherichia coli. | 2014 | Microb. Drug Resist. | pmid:24684286 |
Arenz S et al. | Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide. | 2014 | Nat Commun | pmid:24662426 |
Fernández Fuentes MA et al. | Synergistic activity of biocides and antibiotics on resistant bacteria from organically produced foods. | 2014 | Microb. Drug Resist. | pmid:24660956 |
Heriot WJ et al. | Ocular involvement in a patient with Legionella longbeachae 1 infection. | 2014 | Clin. Experiment. Ophthalmol. | pmid:24650007 |
Calvert H et al. | Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer. | 2014 | Anticancer Drugs | pmid:24637575 |
Janoir C et al. | Clonal expansion of the macrolide resistant ST386 within pneumococcal serotype 6C in France. | 2014 | PLoS ONE | pmid:24603763 |
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Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. | 2014 | J. Fish Dis. | pmid:23992037 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
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Aydin S et al. | Performance of anaerobic sequencing batch reactor in the treatment of pharmaceutical wastewater containing erythromycin and sulfamethoxazole mixture. | 2014 | Water Sci. Technol. | pmid:25429450 |
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Fathollahipour S et al. | Electrospinning of PVA/chitosan nanocomposite nanofibers containing gelatin nanoparticles as a dual drug delivery system. | 2015 | J Biomed Mater Res A | pmid:26112829 |
Abukar AA et al. | Unusual cause of infective endocarditis in an elderly patient with a rare condition. | 2015 | BMJ Case Rep | pmid:25820110 |
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Cui B et al. | Effects of erythromycin on the phenotypic and genotypic biofilm expression in two clinical Staphylococcus capitis subspecies and a functional analysis of Ica proteins in S. capitis. | 2015 | J. Med. Microbiol. | pmid:25813821 |
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