erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cundliffe E and McQuillen K | Peptide bond formation: the effects of antibiotics on the puromycin reaction. | 1968 | J. Gen. Microbiol. | pmid:4968006 |
Garanin BA | [Sensitivity toward antibiotics of Shigella Sonnei of individual fermentative types based on data from a hospital for communicable diseases during 1966]. | 1968 | Antibiotiki | pmid:4877060 |
Calabrò R et al. | [In vitro antibacteric activity of a combination of erythromycin, sulfadiazine, sulfamerazine and sulfamethazine on different bacterial strains]. | 1968 | Boll. Soc. Ital. Biol. Sper. | pmid:4877331 |
Savel'eva TL | [Antibiotics in the treatment of actinomycoses]. | 1968 | Antibiotiki | pmid:4878102 |
RychlÃk I and Cerná J | Cross resistance of Escherichia coli B. ribosomes to inhibition of the puromycin reaction by erythromycin, spiramycin and chloramphenicol. | 1968 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:4878426 |
Kiselev RN | [Intestinal microflora in mice and its change under the effect of antibiotics]. | 1968 | Antibiotiki | pmid:4879870 |
Garanin BA | [Sensitivity toward antibiotics of Shigella, isolated rom the patients in years 1960-1965, from the data from Hospital of Infectious Diseases]. | 1968 | Antibiotiki | pmid:4880237 |
Gomez JR and Gomez G | Comparative trial of erythromycin and tetracycline in common infections found in general practice. | 1968 | Br J Clin Pract | pmid:4880249 |
Kaempfer R | Ribosomal subunit exchange during protein synthesis. | 1968 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4880603 |
Nuzzolo L et al. | [Research on the antibacterial activity in vitro, and on blood concentrations in man, of an association of erythromycin with sulfadiazine, sulfamerazine and sulfamethazine]. | 1968 | Clin Ter | pmid:4883849 |
Avian tuberculosis. | 1968 | Scott Med J | pmid:4884700 | |
Anaka K and Teraoka H | Effect of erythromycin on polylysine synthesis directed by polyadenylic acid in an Escherichia coli cell-free system. | 1968 | J. Biochem. | pmid:4885037 |
Bouanchaud DH et al. | Elimination by ethidium bromide of antibiotic resistance in enterobacteria and staphylococci. | 1968 | J. Gen. Microbiol. | pmid:4885039 |
Tanaka K et al. | Erythromycin-resistant mutant of Escherichia coli with altered ribosomal protein component. | 1968 | Science | pmid:4886608 |
Berthelot et al. | [Clinical study and determination of blood and salivary level of erythromycin ethyl-succinate]. | 1968 | Inf Dent | pmid:5245648 |
Cooper RG et al. | An erythromycin-resistant pneumococcus. | 1968 | Med. J. Aust. | pmid:4385911 |
Lang N et al. | On the mechanism of hormone action. VII. Induction by cortisol of a messenger RNA coding for tyrosine-alpha-ketoglutarate transaminase for an in vitro system. | 1968 | Acta Endocrinol. | pmid:4384442 |
Gurney T and Fox MS | Physical and genetic hybrids formed in bacterial transformation. | 1968 | J. Mol. Biol. | pmid:4384454 |
Osman HG et al. | Utilization of Egyptian raw by-products for the erythromycin production by Streptomyces erythreus. | 1968 | Z. Allg. Mikrobiol. | pmid:4989340 |
Henriksen SD and Bovre K | Moraxella kingii sp.nov., a haemolytic, saccharolytic species of the genus Moraxella. | 1968 | J. Gen. Microbiol. | pmid:5185818 |
Choudhuri KK and Basu Mallick KC | Study of antibiotic-resistant staphylococci isolated from different sources and their role in pathogenicity. | 1968 | Indian J. Med. Res. | pmid:5186305 |
Robertson MH | Tetracycline-resistant streptococci in South-west Essex: a continuing survey. | 1968 | Br Med J | pmid:5186976 |
Postnikova AA | [On the characteristics of staphylococci in chronic osteomyelitis in children]. | 1968 | Antibiotiki | pmid:5187169 |
Clark J et al. | Disseminated infection with Mycobacterium avium: II. Bacteriology and drug susceptibility. | 1968 | Tubercle | pmid:4969144 |
Saggers BA and Lawson D | In vivo penetration of antibiotics into sputum in cystic fibrosis. | 1968 | Arch. Dis. Child. | pmid:4969417 |
Franco S et al. | Erythromycin in childhood pneumonias. | 1968 | Curr Ther Res Clin Exp | pmid:4969674 |
Edmond E et al. | Avian tuberculosis. | 1968 | Scott Med J | pmid:5751239 |
Obojska K and Zawadzka-Gralewicz J | [Combined effect of colistin with neomycin, penicillins and erythromycin on Corynebacterium diphtheriae]. | 1968 | Med Dosw Mikrobiol | pmid:4970248 |
Pulverer G | [Studies with lysotaphin. II. Lysostaphin sensitivity of 230 strains of Staph. aureus of animal origin]. | 1968 | Z Med Mikrobiol Immunol | pmid:5751715 |
Mikuni M et al. | [Present status of chemotherapy in ophthalmology, with special reference to recent antibiotics]. | 1968 | Ganka | pmid:5752591 |
Willcox RR | Erythromycin in the treatment of non-gonococcal urethritis. | 1968 | Br J Vener Dis | pmid:5761021 |
Sabath LD et al. | Enhancing effect on alkalinization of the medium on the activity of erythromycin against gram-negative bacteria. | 1968 | Appl Microbiol | pmid:4970991 |
Schultz EJ | Evaluation of erythromycin in the treatment of infectious bovine mastitis. | 1968 | J. Am. Vet. Med. Assoc. | pmid:5761379 |
Jewett JF et al. | Childbed fever--a continuing entity. | 1968 | JAMA | pmid:4971028 |
Iats'ko VA | [On the dynamics of sensitivity to antibiotics of different microorganisms, isolated from patients of a surgical section]. | 1968 | Antibiotiki | pmid:4971186 |
Betinová M | [Effect of tetracyclines, macrolide antibiotics, and sigmamycin on staphylococci in vitro]. | 1968 | Biologia | pmid:4971503 |
Erythromycin compared with phenoxymethyl-penicillin and tetracycline. | 1968 | Practitioner | pmid:4972106 | |
Ahmed A | Altered ribosomes in spiramycin-resistant mutants of Bacillus subtilis. | 1968 | Biochim. Biophys. Acta | pmid:4972350 |
De Vries JA et al. | Adjunctive use of antibiotics in traumatic dental procedures. | 1968 | Int Z Klin Pharmakol Ther Toxikol | pmid:4972570 |
Rotheim MB and Ravin AW | Inactivation and reversion of multisite streptomycin resistance mutations of Pneumococcus. | 1968 | Mol. Gen. Genet. | pmid:5713396 |
Onodera T et al. | Effect of fluid and antibiotic administration on experimental fecal peritonitis. | 1968 | Tohoku J. Exp. Med. | pmid:5715596 |
Smith LT et al. | Reproductive performance of pheasant breeder hens. | 1968 | Poult. Sci. | pmid:5716660 |
Velluti G and Grifa P | [In vitro activity of erythromycin on various mycobacterium strains]. | 1968 | G Mal Infett Parassit | pmid:4976935 |
Levy A et al. | [Study "in vitro" and "in vivo" using erythromycin stearate in the therapy of respiratory and cutaneous infections]. | 1968 | Rev Bras Med | pmid:5717048 |
Acocella G et al. | Biliary excretion of antibiotics in man. | 1968 | Gut | pmid:5717103 |
Voors AW and Stewart GT | Statistical analysis of staphylococcal infection in hospital patients in relation to use of antibiotics and other factors. | 1968 | J Hyg (Lond) | pmid:5250128 |
Kanno M et al. | [Study on progressive muscular dystrophy. 1. Influence of the various drugs on serum enzyme activity and the degree of disability]. | 1968 | Iryo | pmid:5717702 |
Schlecht S and Westphal O | [Antibiotic sensitivity in S- and R-forms of Salmonella minnesota]. | 1968 | Naturwissenschaften | pmid:5725584 |
Hejzlar M et al. | Ten-year study of Neisseria gonorrhoeae sensitivity to antibiotics in Czechoslovakia. | 1968 | J Hyg Epidemiol Microbiol Immunol | pmid:4977454 |
Akzhigitov GH et al. | [The treatment of traumatic pancreatitis with antibiotics and their secretion with pancreatic juice]. | 1968 | Vestn. Khir. Im. I. I. Grek. | pmid:5729234 |
Ocklitz HW et al. | [Pediatric guidelines. 3. Antibiotics--indications]. | 1968 | Z Arztl Fortbild (Jena) | pmid:4978334 |
Sugiyama H | [Experimental studies on control of dental caries. 2. Erythromycin and oral microbial flora]. | 1968 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5261349 |
Mao JC and Wiegand RG | Mode of action of macrolides. | 1968 | Biochim. Biophys. Acta | pmid:5649911 |
da Silva WB et al. | [Use of a chloramphenicol-erythromycin combination in the treatment of lung diseases in children]. | 1968 | Hospital (Rio J) | pmid:5308493 |
Puito L | [Antibiotic therapy in infancy]. | 1968 | Pediatria (Napoli) | pmid:4312284 |
Jones PH and Rowley EK | Chemical modifications of erythromycin antibiotics. I. 3'-de(dimethylamino)erythromycin A and B. | 1968 | J. Org. Chem. | pmid:5636610 |
Thomas DY and Wilkie D | Recombination of mitochondrial drug-resistance factors in Saccharomyces cerevisiae. | 1968 | Biochem. Biophys. Res. Commun. | pmid:5637042 |
Petit JF et al. | Biosynthesis of the peptidoglycan of bacterial cell walls. VII. Incorporation of serine and glycine into interpeptide bridges in Staphylococcus epidermidis. | 1968 | J. Biol. Chem. | pmid:5638592 |
Hanley JE et al. | An evaluation and comparison of spectinomycin and spectinomycin-erythromycin combinations for infectious coryza. | 1968 | Avian Dis. | pmid:5643698 |
Breitfellner G et al. | [Staphylococci in the Vienna area. Epidemiology, antibiotic sensitivity and therapeutic aspects]. | 1968 | Wien. Klin. Wochenschr. | pmid:5188335 |
Sotaniemi E and Huhti E | Bronchial asthma and toxic hepatitis. | 1968 | Ann Allergy | pmid:5644356 |
Parisi JT and Suling WJ | Antibiotic resistance of glycine-resistant variants of Staphylococcus aureus. | 1968 | Can. J. Microbiol. | pmid:5188340 |
Desmyter J | Lincomycin resistance of erythromycin-resistant cocci. | 1968 | N. Engl. J. Med. | pmid:5644571 |
Bulger RJ and Sherris JC | Decreased incidence of antibiotic resistance among Staphylococcus aureus. A study in a university hospital over a 9-year period. | 1968 | Ann. Intern. Med. | pmid:5188901 |
Popovici GG et al. | The influence of some antibiotics on glucose-6-P-NADP-oxido-reductase (G6PDH) activity. | 1968 | Arch Int Pharmacodyn Ther | pmid:5646007 |
Sprunt K et al. | Penicillin resistant alpha Streptococci in pharynx of patients given oral penicillin. | 1968 | Pediatrics | pmid:5188913 |
Novick RP and Roth C | Plasmid-linked resistance to inorganic salts in Staphylococcus aureus. | 1968 | J. Bacteriol. | pmid:5646621 |
Alberti RL | Teeth discoloration and enamel hypoplasia caused by erythromycin. | 1968 | S. Afr. Med. J. | pmid:5647172 |
Doyle WM et al. | Pulmonary disease caused by Mycobacterium xenopei. | 1968 | Am. Rev. Respir. Dis. | pmid:5647216 |
Thomas DY and Wilkie D | Inhibition of mitochondrial synthesis in yeast by erythromycin: cytoplasmic and nuclear factors controlling resistance. | 1968 | Genet. Res. | pmid:5648765 |
Amato Neto V and Wanderley RA | [Use of an erythromycin stearate preparation, of regulated intestinal release in the treatment of intestinal amebiasis]. | 1968 | Hospital (Rio J) | pmid:5311770 |
Osman HG et al. | Factors influencing the biosynthesis of erythromycin by Streptomyces erythreus. | 1968 | Z. Allg. Mikrobiol. | pmid:4916831 |
Forshaw J | Penicillin-induced granulopenia. | 1968 | Br Med J | pmid:5662555 |
Zabalueva TS et al. | [Sensitivity to antibiotics of staphylococci, isolated in city of Gor'kiu]. | 1968 | Antibiotiki | pmid:4237512 |
Mezey E et al. | Serum alcohol dehydrogenase, an indicator of intrahepatic cholestasis. | 1968 | N. Engl. J. Med. | pmid:5662777 |
The macrolides and lincomycin. | 1968 | Br Med J | pmid:5662980 | |
Simon C and Latz E | [Antibiotic therapy of staphylococcal infections. The influence of chloramphenicol and erythromycin on the bactericidal effect of penicillin G and methicillin in vitro]. | 1968 | Med Welt | pmid:5663162 |
Narasimhan MJ and Ganla VG | The broad-spectrum and the macrolide antibiotics and the ciliary barrier. | 1968 | Hindustan Antibiot Bull | pmid:5663533 |
Bertrand JL | [Combination of propionyl-erythromycin, tetracycline and lysozyme in anti-infective therapy in adults and children]. | 1968 | Lyon Med | pmid:5664960 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. 3. Occurrence and spread of "type 6557", with special reference to the consumption of some antibiotics. | 1968 | Acta Pathol Microbiol Scand | pmid:4244485 |
Lamb AJ et al. | The biogenesis of mitochondria. 4. The differentiation of mitochondrial and cytoplasmic protein synthesizing systems in vitro by antibiotics. | 1968 | Biochim. Biophys. Acta | pmid:5667290 |
Davis CM et al. | The value of neomycin in a neomycin-steroid cream. | 1968 | JAMA | pmid:4294840 |
Levin HS and Kagan BM | Antimicrobial agents: pediatric dosage, routes of administration and preparation procedures for parenteral therapy. | 1968 | Pediatr. Clin. North Am. | pmid:4295551 |
Macfarlane JA et al. | Spiramycin the the prevention of postoperative staphylococcal infection. | 1968 | Lancet | pmid:4169066 |
Banaszek A et al. | Thin-layer and column chromatography of erythromycins and some degradation products. | 1968 | J. Chromatogr. | pmid:4295864 |
Pacha RE | Characteristics of Cytophaga psychrophila (Borg) isolated during outbreaks of bacterial cold-water disease. | 1968 | Appl Microbiol | pmid:4169926 |
Chisholm WS | Erythromycin-sulfas in pediatric practice: efficacy and patient acceptance. | 1968 | Ariz Med | pmid:5674274 |
Martin JR and Perun TJ | Studies on the biosynthesis of the erythromycins. 3. Isolation and structure of 5-deoxy-5-oxoerythronolide B, a shunt metabolite of erythromycin biosynthesis. | 1968 | Biochemistry | pmid:4297053 |
Johnstone FR and Cockcroft WH | Clostridium welchii resistance to tetracycline. | 1968 | Lancet | pmid:4170649 |
Higashide E et al. | Enduracidin, a new antibiotic. I. Streptomyces fungicidicus No. B5477, an enduracidin producing organism. | 1968 | J. Antibiot. | pmid:5674368 |
Chevallier MR et al. | [Halogenation of ribonucleic acids. VI. Influence of bromination on the transforming activity of Haemophilus influenzae DNA]. | 1968 | Bull. Soc. Chim. Biol. | pmid:4297076 |
Hadida E et al. | [Dissecting cellulitis of the scalp]. | 1968 | Bull Soc Fr Dermatol Syphiligr | pmid:5677894 |
McGehee RF et al. | Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. | 1968 | Am. J. Med. Sci. | pmid:4386950 |
Chernomordik AB | [Antibiotic lincomycin]. | 1968 | Antibiotiki | pmid:4894135 |
VaÄsberg GE and Meshkov MI | [Treatment of patients with microbial eczema by prodigiozan in combination with antibiotics]. | 1968 | Antibiotiki | pmid:5678111 |
Gause GG and Grünberger D | Translational characteristics of ribosomes and coding properties of transfer RNA in the mutant of bacterium paracoli with the increased GC content of DNA. | 1968 | Biochim. Biophys. Acta | pmid:5680608 |
Ganança MM | [Use of erythromycin suppositories in the treatment of otorhinolaryngologic infections in children]. | 1968 | Hospital (Rio J) | pmid:5307873 |
Siegenthaler W et al. | [New antibiotics, with the exception of penicillins, streptomycin, tetracyclines and chloramphenicol]. | 1968 | Antibiot Chemother | pmid:4302993 |
Minkova GL | [On the sensitivity of microflora of burn wounds to antibiotics]. | 1968 | Antibiotiki | pmid:4305269 |
Baskanchiladze GSh and Buniatova IM | [Change in the sensitivity to antibiotics of pathogenic staphylococci, isolated in Tiflis during 1961-1966]. | 1968 | Antibiotiki | pmid:4303353 |