erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nemeghaire S et al. | Characterization of methicillin-resistant Staphylococcus aureus from healthy carrier chickens. | 2013 | Avian Pathol. | pmid:23777220 |
Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Yun SH et al. | Demodex folliculitis presenting as periocular vesiculopustular rash. | 2013 | Orbit | pmid:23895342 |
Jiang M et al. | Deoxysugar pathway interchange for erythromycin analogues heterologously produced through Escherichia coli. | 2013 | Metab. Eng. | pmid:24060454 |
Desroy N et al. | Novel HldE-K inhibitors leading to attenuated Gram negative bacterial virulence. | 2013 | J. Med. Chem. | pmid:23409840 |
Chang YC and Lo HH | Identification, clinical aspects, susceptibility pattern, and molecular epidemiology of beta-haemolytic group G Streptococcus anginosus group isolates from central Taiwan. | 2013 | Diagn. Microbiol. Infect. Dis. | pmid:23632249 |
Müller M et al. | The absolute configuration of (+)- and (-)-erythro-mefloquine. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23616269 |
Simoens S et al. | Preventing COPD exacerbations with macrolides: a review and budget impact analysis. | 2013 | Respir Med | pmid:23352223 |
Teske L et al. | Epidemiological investigations on the possible risk of distribution of zoonotic bacteria through apparently healthy homing pigeons. | 2013 | Avian Pathol. | pmid:23930968 |
Heelan K et al. | Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. | 2012 Sep-Oct | Pediatr Dermatol | pmid:21906149 |
Lian W et al. | Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. | 2012 Oct-Dec | Biosens Bioelectron | pmid:22683249 |
Hapa A et al. | Childhood pityriasis lichenoides and oral erythromycin. | 2012 Nov-Dec | Pediatr Dermatol | pmid:22639857 |
Asai N et al. | A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. | 2012 Nov-Dec | J Bras Pneumol | pmid:23288130 |
Clementson B and Smidt AC | Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. | 2012 May-Jun | Pediatr Dermatol | pmid:22122785 |
Kuhn M et al. | Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. | 2012 Jul-Aug | Berl. Munch. Tierarztl. Wochenschr. | pmid:22919930 |
Jiang RS et al. | Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. | 2012 Jul-Aug | Am J Rhinol Allergy | pmid:22801017 |
Kuehne SA and Minton NP | ClosTron-mediated engineering of Clostridium. | 2012 Jul-Aug | Bioengineered | pmid:22750794 |
Miguel AI et al. | Pediatric ocular rosacea: 2 cases. | 2012 Jul-Aug | Eur J Ophthalmol | pmid:22267454 |
Amatya A et al. | Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. | 2012 Jan-Mar | Kathmandu Univ Med J (KUMJ) | pmid:22971864 |
Zhang H et al. | Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. | 2012 Jan-Feb | Biotechnol. Prog. | pmid:21905273 |
Pehr K | Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. | 2012 Jan-Feb | J Cutan Med Surg | pmid:22417996 |
Sakatis MZ et al. | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. | 2012 | Chem. Res. Toxicol. | pmid:22931300 |
Li SL et al. | A single tube modified allele-specific-PCR for rapid detection of erythromycin-resistant Mycoplasma pneumoniae in Beijing. | 2012 | Chin. Med. J. | pmid:22931973 |
Waśko A et al. | Genetic mechanisms of variation in erythromycin resistance in Lactobacillus rhamnosus strains. | 2012 | J. Antibiot. | pmid:22948255 |
Leyden JJ | In vivo antibacterial effects of tretinoin-clindamycin and clindamycin alone on Propionibacterium acnes with varying clindamycin minimum inhibitory. | 2012 | J Drugs Dermatol | pmid:23377513 |
Hess TM and Chew HF | Successful treatment of acute ocular involvement in Stevens-Johnson syndrome with amniotic membrane transplantation: a case report. | 2012 | Can. J. Ophthalmol. | pmid:23217513 |
Fazeli M et al. | Erythromycin enhances abomasal emptying in healthy unweaned lambs as shown by acetaminophen absorption test. | 2012 | J. Vet. Pharmacol. Ther. | pmid:22066489 |
Villaseñor-Sierra A et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. | 2012 | Int. J. Infect. Dis. | pmid:22217469 |
Luangtongkum T et al. | Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. | 2012 | Antimicrob. Agents Chemother. | pmid:22183170 |
Soeters HM et al. | Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease. | 2012 | Antimicrob. Agents Chemother. | pmid:22232291 |
Sunkara B et al. | Group B Streptococcus infections in non-pregnant adults: the role of immunosuppression. | 2012 | Int. J. Infect. Dis. | pmid:22236484 |
Mansouri-najand L et al. | Prevalence of multidrug resistance Campylobacter jejuni and Campylobacter coli in chickens slaughtered in selected markets, Malaysia. | 2012 | Trop Biomed | pmid:22735845 |
Shi JG et al. | The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers. | 2012 | J Clin Pharmacol | pmid:21602517 |
Wormser GP et al. | Failure of topical antibiotics to prevent disseminated Borrelia burgdorferi infection following a tick bite in C3H/HeJ mice. | 2012 | J. Infect. Dis. | pmid:21930606 |
Kanazu T et al. | Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. | 2012 | Biopharm Drug Dispos | pmid:22447511 |
Liu X et al. | Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment. | 2012 | Toxicol. Lett. | pmid:22450446 |
Rahube TO and Yost CK | Characterization of a mobile and multiple resistance plasmid isolated from swine manure and its detection in soil after manure application. | 2012 | J. Appl. Microbiol. | pmid:22486928 |
Campelo FA et al. | [Phenotypes and mechanisms of resistance to macrolides and lincosamides in Streptococcus agalactiae isolates with clinical significance in an eight-year period (2002-2010)]. | 2012 | Rev Esp Quimioter | pmid:22488541 |
Imai Y et al. | Development of the ability to produce secondary metabolites in Streptomyces through the acquisition of erythromycin resistance. | 2012 | J. Antibiot. | pmid:22491137 |
Diacon AH et al. | Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22391540 |
Peano C et al. | Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. | 2012 | Microb. Cell Fact. | pmid:22401291 |
Chen CM | Erythromycin for the treatment of feeding intolerance in preterm infants. | 2012 | Pediatr Neonatol | pmid:22348487 |
Ng YY et al. | Efficacy of intermediate-dose oral erythromycin on very low birth weight infants with feeding intolerance. | 2012 | Pediatr Neonatol | pmid:22348492 |
Yoon SB et al. | The effect of exenatide and erythromycin on postprandial symptoms and their relation to gastric functions. | 2012 | Digestion | pmid:22354133 |
Chhun S et al. | The cytochrome P-450 2C9/2C19 but not the ABCB1 genetic polymorphism may be associated with the liver cytochrome 3A4 induction by phenytoin. | 2012 | J Clin Psychopharmacol | pmid:22561479 |
Ohene-Agyei T et al. | Mutations in MexB that affect the efflux of antibiotics with cytoplasmic targets. | 2012 | FEMS Microbiol. Lett. | pmid:22568688 |
He JL et al. | [Distribution of anaerobes in periodontal abscess and its resistance to antibiotics]. | 2012 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:23328096 |
Du Plessis LH et al. | In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum. | 2012 | J. Antibiot. | pmid:23093037 |
Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible resistance to erythromycin in Streptococcus pyogenes. | 2012 | Antimicrob. Agents Chemother. | pmid:23027190 |
PiÄ…tkowska E et al. | The strongest resistance of Staphylococcus aureus to erythromycin is caused by decreasing uptake of the antibiotic into the cells. | 2012 | Cell. Mol. Biol. Lett. | pmid:23001512 |