erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Respiratory Insufficiency D012131 10 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Ischemia D007511 18 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Thromboembolism D013923 6 associated lipids
Periodontitis D010518 22 associated lipids
Dermatitis D003872 30 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Vomiting D014839 21 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Streptococcal Infections D013290 4 associated lipids
Otitis D010031 5 associated lipids
Cholelithiasis D002769 16 associated lipids
Fever D005334 35 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Pneumonia D011014 10 associated lipids
Conjunctivitis D003231 7 associated lipids
Syphilis D013587 6 associated lipids
Chorioamnionitis D002821 5 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Hearing Disorders D006311 10 associated lipids
Duodenitis D004382 4 associated lipids
Death, Sudden D003645 12 associated lipids
Cardiomegaly D006332 31 associated lipids
Tachycardia D013610 7 associated lipids
Common Cold D003139 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Foot Diseases D005534 4 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Neutropenia D009503 15 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Urticaria D014581 13 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
HIV Seropositivity D006679 15 associated lipids
Uveitis D014605 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Liu J et al. Preparation and characterization of erythromycin molecularly imprinted polymers based on distillation-precipitation polymerization. 2015 J Sep Sci pmid:26118901
Fathollahipour S et al. Electrospinning of PVA/chitosan nanocomposite nanofibers containing gelatin nanoparticles as a dual drug delivery system. 2015 J Biomed Mater Res A pmid:26112829
Xing L et al. ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer. 2015 PLoS ONE pmid:26107936
Dridi B et al. Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. 2015 Antimicrob. Agents Chemother. pmid:26100702
Czarnetzki C et al. Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial. 2015 JAMA Surg pmid:26083537
Patti MG Erythromycin Use Before Induction of General Endotracheal Anesthesia. 2015 JAMA Surg pmid:26083012
Haenen CC et al. [Rosacea fulminans in pregnancy]. 2015 Ned Tijdschr Geneeskd pmid:26058762
Gagliotti C et al. A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. 2015 Acta Paediatr. pmid:26058421
Dermota U et al. Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. 2015 Int. J. Med. Microbiol. pmid:26055648
Aydin S et al. Combined effect of erythromycin, tetracycline and sulfamethoxazole on performance of anaerobic sequencing batch reactors. 2015 Bioresour. Technol. pmid:25817031
Cui B et al. Effects of erythromycin on the phenotypic and genotypic biofilm expression in two clinical Staphylococcus capitis subspecies and a functional analysis of Ica proteins in S. capitis. 2015 J. Med. Microbiol. pmid:25813821
Chew ML et al. Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial. 2015 Clin Drug Investig pmid:25808394
Ericson JE et al. Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. 2015 J. Pediatr. Gastroenterol. Nutr. pmid:25806675
Aydin S et al. Application of real-time PCR to determination of combined effect of antibiotics on Bacteria, Methanogenic Archaea, Archaea in anaerobic sequencing batch reactors. 2015 Water Res. pmid:25792437
Zhu Y et al. Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". 2015 Sci Rep pmid:25791905
Wang P et al. Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. 2015 PLoS ONE pmid:25781346
Zhou Y et al. Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. 2015 Talanta pmid:25770599
Tojima I et al. Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. 2015 Auris Nasus Larynx pmid:25769240
Hao H et al. Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. 2015 J. Appl. Microbiol. pmid:25766481
Nonaka L et al. Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. 2015 Lett. Appl. Microbiol. pmid:25765542
Sakata H The change of macrolide resistance rates in group A Streptococcus isolates from children between 2002 and 2013 in Asahikawa city. 2015 J. Infect. Chemother. pmid:25618777
Johnson AC et al. Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers. 2015 Sci. Total Environ. pmid:25617699
Wang P et al. Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas. 2015 Microb. Cell Fact. pmid:25612661
Chiaverini C et al. Oral erythromycin therapy in epidermolysis bullosa simplex generalized severe. 2015 Br. J. Dermatol. pmid:25601422
Li Z et al. New erythromycin derivatives enhance β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. 2015 Lett. Appl. Microbiol. pmid:25588530
Gardiner SJ et al. Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. 2015 Cochrane Database Syst Rev pmid:25566754
Azadegan A et al. Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. 2015 Ann Lab Med pmid:25553281
Wu H et al. Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. 2015 Appl. Microbiol. Biotechnol. pmid:25549616
Cetecioglu Z et al. Acute effect of erythromycin on metabolic transformations of volatile fatty acid mixture under anaerobic conditions. 2015 Chemosphere pmid:25542637
Marín M et al. Clostridium difficile isolates with high linezolid MICs harbor the multiresistance gene cfr. 2015 Antimicrob. Agents Chemother. pmid:25385106
Igbinosa IH Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals. 2015 Trop Anim Health Prod pmid:25348646
Wang Z et al. Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk. 2015 Food Chem pmid:25308648
Hawkins PA et al. Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States. 2015 Microb. Drug Resist. pmid:25115711
Vallianou N et al. Prevalence of macrolide, lincosamide, and streptogramin resistance among staphylococci in a tertiary care hospital in Athens, Greece. 2015 J Chemother pmid:25112954
Kempe H et al. Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. 2015 Pharm. Res. pmid:25103333
Yang J et al. Improving heterologous polyketide production in Escherichia coli by transporter engineering. 2015 Appl. Microbiol. Biotechnol. pmid:26062534
Muralidharan V and Striepen B Teaching old drugs new tricks to stop malaria invasion in its tracks. 2015 BMC Biol. pmid:26349580
Pavlova A and Gumbart JC Parametrization of macrolide antibiotics using the force field toolkit. 2015 J Comput Chem pmid:26280362
Feng T et al. Insights into resistance mechanism of the macrolide biosensor protein MphR(A) binding to macrolide antibiotic erythromycin by molecular dynamics simulation. 2015 J. Comput. Aided Mol. Des. pmid:26564143
Daghighi S et al. Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. 2015 Int. J. Antimicrob. Agents pmid:26526893
Bravo-Rodriguez K et al. Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. 2015 Chem. Biol. pmid:26526102
Bérard A et al. Use of macrolides during pregnancy and the risk of birth defects: a population-based study. 2015 Pharmacoepidemiol Drug Saf pmid:26513406
Arinto-Garcia R et al. Comparing Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and Phenotypic and Molecular Methods for Identification of Species within the Streptococcus anginosus Group. 2015 J. Clin. Microbiol. pmid:26354817
Han X et al. Synthesis and structure-activity relationships of novel 9-oxime acylides with improved bactericidal activity. 2015 Bioorg. Med. Chem. pmid:26349628
Wróblewska M and Winnicka K The Effect of Cationic Polyamidoamine Dendrimers on Physicochemical Characteristics of Hydrogels with Erythromycin. 2015 Int J Mol Sci pmid:26343637
Bolukaoto JY et al. Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. 2015 BMC Res Notes pmid:26289147
Liao CH et al. DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea. 2015 Appl. Microbiol. Biotechnol. pmid:26272095
Å mitran A et al. Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin. 2015 Mem. Inst. Oswaldo Cruz pmid:26270594
Wang YL et al. Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry. 2015 Foodborne Pathog. Dis. pmid:26258263
Prohl A et al. Enrofloxacin and macrolides alone or in combination with rifampicin as antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection. 2015 PLoS ONE pmid:25768665