erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
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Wu L et al. Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. 2016 PLoS ONE pmid:27447724
Kwon JW Environmental impact assessment of veterinary drug on fish aquaculture for food safety. 2016 Drug Test Anal pmid:27443211
Aslan Bayhan S et al. Effects of topical acne treatment on the ocular surface in patients with acne vulgaris. 2016 Cont Lens Anterior Eye pmid:27422575
Li X et al. Effects of Total Alkaloids of Sophora alopecuroides on Biofilm Formation in Staphylococcus epidermidis. 2016 Biomed Res Int pmid:27413745
Ababou A and Koronakis V Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. 2016 PLoS ONE pmid:27403665
Yuan QB et al. Reductions of bacterial antibiotic resistance through five biological treatment processes treated municipal wastewater. 2016 Environ Sci Pollut Res Int pmid:27384166
Karlsson E et al. Clonality of erythromycin resistance in Francisella tularensis. 2016 J. Antimicrob. Chemother. pmid:27334667
Changchien CH et al. Antibiotic susceptibility and genomic variations in Staphylococcus aureus associated with Skin and Soft Tissue Infection (SSTI) disease groups. 2016 BMC Infect. Dis. pmid:27287530
Waiser MJ et al. Effects of erythromycin, trimethoprim and clindamycin on attached microbial communities from an effluent dominated prairie stream. 2016 Ecotoxicol. Environ. Saf. pmid:27261880
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Pignatello R et al. Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. 2016 Eur J Med Chem pmid:27236014
Mushtaq A et al. Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva. 2016 Antimicrob. Agents Chemother. pmid:27216060
Hong M et al. Impacts of proline on the central metabolism of an industrial erythromycin-producing strain Saccharopolyspora erythraea via (13)C labeling experiments. 2016 J. Biotechnol. pmid:27215341
Stacevičienė I et al. Antibiotic resistance of Streptococcus pneumoniae, isolated from nasopharynx of preschool children with acute respiratory tract infection in Lithuania. 2016 BMC Infect. Dis. pmid:27206423
Tatiya-Aphiradee N et al. In vivo antibacterial activity of Garcinia mangostana pericarp extract against methicillin-resistant Staphylococcus aureus in a mouse superficial skin infection model. 2016 Pharm Biol pmid:27180784
Trac MH et al. Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. 2016 CMAJ pmid:26903359
He M et al. Mechanism of synergy between SIPI-8294 and β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. 2016 Lett. Appl. Microbiol. pmid:27173151
Patel MB et al. Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. 2016 Bioorg. Med. Chem. pmid:27166575
Mendes RE et al. In Vitro Activity of Lefamulin Tested against Streptococcus pneumoniae with Defined Serotypes, Including Multidrug-Resistant Isolates Causing Lower Respiratory Tract Infections in the United States. 2016 Antimicrob. Agents Chemother. pmid:27161634
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Tan C et al. Effects of Low-Dose and Long-Term Treatment with Erythromycin on Interleukin-17 and Interleukin-23 in Peripheral Blood and Induced Sputum in Patients with Stable Chronic Obstructive Pulmonary Disease. 2016 Mediators Inflamm. pmid:27127346
Guo Q et al. Controlling the feed rate of propanol to optimize erythromycin fermentation by on-line capacitance and oxygen uptake rate measurement. 2016 Bioprocess Biosyst Eng pmid:26615414
Zheng Z et al. Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. 2016 J. Antibiot. pmid:27118243
Mikhail M et al. Orbital cellulitis and multiple abscess formation after strabismus surgery. 2016 Can. J. Ophthalmol. pmid:27085279
Zhang A et al. Molecular subtyping and erythromycin resistance of Campylobacter in China. 2016 J. Appl. Microbiol. pmid:26999516
Mukai S et al. Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. 2016 Int. J. Oncol. pmid:26718641
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Ohbatake Y et al. Elevated alpha1-acid glycoprotein in gastric cancer patients inhibits the anticancer effects of paclitaxel, effects restored by co-administration of erythromycin. 2016 Clin. Exp. Med. pmid:26359244
Templeton I et al. A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4. 2016 Biopharm Drug Dispos pmid:26356245
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