erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

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Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Krokidis MG et al. Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis. 2014 Antimicrob. Agents Chemother. pmid:24189263
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Khannous L et al. Isolation of a novel amylase and lipase-producing Pseudomonas luteola strain: study of amylase production conditions. 2014 Lipids Health Dis pmid:24405763
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Ziupa D et al. Pronounced effects of HERG-blockers E-4031 and erythromycin on APD, spatial APD dispersion and triangulation in transgenic long-QT type 1 rabbits. 2014 PLoS ONE pmid:25244401
Westerhof J et al. Completion rate of small bowel capsule endoscopy is higher after erythromycin compared to domperidone. 2014 BMC Gastroenterol pmid:25234278
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Labbeiki G et al. Enhanced oxygen transfer rate and bioprocess yield by using magnetite nanoparticles in fermentation media of erythromycin. 2014 Daru pmid:25223458
Bharucha AE et al. A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography. 2014 Eur J Radiol pmid:25217123
Kemp MW et al. Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. 2014 Am. J. Obstet. Gynecol. pmid:24589547
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Hoover WD et al. Topical antibiotic monotherapy prescribing practices in acne vulgaris. 2014 J Dermatolog Treat pmid:24171409
Yeung SW et al. Comparison of the effect of penicillins versus erythromycin in preventing neonatal group B streptococcus infection in active carriers following preterm prelabor rupture of membranes. 2014 Taiwan J Obstet Gynecol pmid:25017269
Nuyujukian DS et al. Medication use and multiple myeloma risk in Los Angeles County. 2014 Cancer Causes Control pmid:24981100
Iatrou EI et al. Consumption-based approach for predicting environmental risk in Greece due to the presence of antimicrobials in domestic wastewater. 2014 Environ Sci Pollut Res Int pmid:24981036
Ramos V et al. [Mobile genetic elements associated with erythromycin-resistant isolates of Streptococcus pneumoniae in Colombia]. 2014 Biomedica pmid:24968052
Moore KT et al. An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function. 2014 J Clin Pharmacol pmid:24964176
Montilla A et al. Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate. 2014 Antimicrob. Agents Chemother. pmid:24957835
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Arenz S et al. Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide. 2014 Nat Commun pmid:24662426
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Chan BC et al. Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. 2015 J. Pharm. Pharmacol. pmid:25212982
Shishkina AV et al. Modeling Interactions of Erythromycin Derivatives with Ribosomes. 2015 Biochemistry Mosc. pmid:26615442
Yang Y et al. Variation in Bordetella pertussis Susceptibility to Erythromycin and Virulence-Related Genotype Changes in China (1970-2014). 2015 PLoS ONE pmid:26406905
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