erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Scleritis D015423 3 associated lipids
Weight Gain D015430 101 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Torsades de Pointes D016171 2 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Bacteremia D016470 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Carbonell N et al. Erythromycin infusion prior to endoscopy for acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial. 2006 Am. J. Gastroenterol. pmid:16771939
Glupczynski Y and Burette A Failure of azythromycin to eradicate Campylobacter pylori from the stomach because of acquired resistance during treatment. 1990 Am. J. Gastroenterol. pmid:2153337
Maganti K et al. Oral erythromycin and symptomatic relief of gastroparesis: a systematic review. 2003 Am. J. Gastroenterol. pmid:12591038
Janssen P et al. The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. 2013 Am. J. Gastroenterol. pmid:24005344
DiBaise JK et al. Effects of low doses of erythromycin on the 13C Spirulina platensis gastric emptying breath test and electrogastrogram: a controlled study in healthy volunteers. 2001 Am. J. Gastroenterol. pmid:11467630
DITTLER EL Upper abdominal pain and intrahepatic cholestasis as manifestations of sensitivity to ilosone. 1962 Am. J. Gastroenterol. pmid:14028076
VIRANUVATTI V and BISESHURARIT P Clinical trial of erythromycin in amebic liver abscess. 1955 Am. J. Gastroenterol. pmid:13228406
Hakkal HG Pseudomembraneous colitis associated with antibiotics. 1976 Am. J. Gastroenterol. pmid:1274934
Jones KL et al. The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. 1999 Am. J. Gastroenterol. pmid:10445530
Fiorucci S et al. Effect of erythromycin on gastric and gallbladder emptying and gastrointestinal symptoms in scleroderma patients is maintained medium term. 1994 Am. J. Gastroenterol. pmid:8147358
Resnick J et al. Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. 1997 Am. J. Gastroenterol. pmid:9177505
Camilleri M The current role of erythromycin in the clinical management of gastric emptying disorders. 1993 Am. J. Gastroenterol. pmid:8424415
Keshavarzian A and Isaac RM Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. 1993 Am. J. Gastroenterol. pmid:8424419
Mantides A et al. The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. 1993 Am. J. Gastroenterol. pmid:8424420
Weber FH et al. Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. 1993 Am. J. Gastroenterol. pmid:8470625
Ruffin WK Erythromycin: a postoperative jumpstart? 1994 Am. J. Gastroenterol. pmid:7909647
CURTIN JA THE EFFECT OF ANTIBIOTICS UPON THE GASTROINTESTINAL TRACT. 1964 Am. J. Gastroenterol. pmid:14206198
McNulty CA The treatment of Campylobacter-associated gastritis. 1987 Am. J. Gastroenterol. pmid:3493685
Koutsoumbi P et al. The effect of erythromycin on human esophageal motility is mediated by serotonin receptors. 2000 Am. J. Gastroenterol. pmid:11151866
Portincasa P et al. The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study. 2000 Am. J. Gastroenterol. pmid:11151875
Ecker JA et al. Pseudomembraneous enterocolitis--an unwelcome gastrointestinal complication of antibiotic therapy. 1970 Am. J. Gastroenterol. pmid:4319211
Moussa F et al. Erythromycin eye ointment: effect on gastrointestinal motility. 2000 Am. J. Gastroenterol. pmid:10710093
Kalkay MN et al. Campylobacter-induced toxic megacolon. 1983 Am. J. Gastroenterol. pmid:6613968
Nolan CM et al. Campylobacter jejuni enteritis: efficacy of antimicrobial and antimotility drugs. 1983 Am. J. Gastroenterol. pmid:6624735
Masclee AA et al. Effect of erythromycin on gallbladder emptying in patients with antrectomy or truncal vagotomy. 1995 Am. J. Gastroenterol. pmid:7771433
Slotkin RI et al. The effect of antibiotics on Mycoplasma pneumoniae in vitro and in vivo. 1967 Am. J. Epidemiol. pmid:5006447
Patamasucon P et al. Oral v topical erythromycin therapies for chlamydial conjunctivitis. 1982 Am. J. Dis. Child. pmid:7051813
Rodriguez WJ et al. Erythromycin-sulfisoxazole vs amoxicillin in the treatment of acute otitis media in children. A double-blind, multiple-dose comparative study. 1985 Am. J. Dis. Child. pmid:3895889
Derrick CW and Dillon HC Erythromycin therapy for streptococcal pharyngitis. 1976 Am. J. Dis. Child. pmid:766615
BURNS L and HODGMAN J STUDIES OF PREMATURES GIVEN ERYTHROMYCIN ESTOLATE. 1963 Am. J. Dis. Child. pmid:14057607
Bass JW et al. Antimicrobials in the treatment of acute otitis media. A second clinical trial. 1973 Am. J. Dis. Child. pmid:4632555
Derrick CW and Dillon HC Streptococcal pharyngitis therapy. A comparison of two erythromycin formulations. 1979 Am. J. Dis. Child. pmid:389036
Pai CH et al. Erythromycin in treatment of Campylobacter enteritis in children. 1983 Am. J. Dis. Child. pmid:6600579
Disney FA and Pichichero ME Treatment of Staphylococcus aureus infections in children in office practice. 1983 Am. J. Dis. Child. pmid:6600877
Wannamaker LW Perplexity and precision in the diagnosis of streptococcal pharyngitis. 1972 Am. J. Dis. Child. pmid:5056872
Fischer PR and Shigeoka AO Familial occurrence of Stevens-Johnson syndrome. 1983 Am. J. Dis. Child. pmid:6604452
Ginsburg CM et al. Erythromycin therapy for group A streptococcal pharyngitis. Results of a comparative study of the estolate and ethylsuccinate formulations. 1984 Am. J. Dis. Child. pmid:6372437
Hughes WT and Collier RN Streptococcal pharyngitis. Evaluation of erythromycin, erythromycin-sulfas, and sulfamethoxazole (possible antagonism between erythromycin and sulfas). 1969 Am. J. Dis. Child. pmid:5348368
Dillon HC and Ware JC Sources and susceptibilities of staphylococci isolated from children. A seven-year survey. 1981 Am. J. Dis. Child. pmid:7234768
Robins-Browne RM et al. Treatment of Campylobacter-associated enteritis with erythromycin. 1983 Am. J. Dis. Child. pmid:6337473
Warkany J A warfarin embryopathy? 1975 Am. J. Dis. Child. pmid:1121959
Khuri-Bulos N et al. Bacteroides brain abscess treated with clindamycin. 1973 Am. J. Dis. Child. pmid:4723176
Davis SD et al. Partial antibiotic therapy in Haemophilus infuenzae meningitis. Its effect on cerebrospinal fluid abnormalities. 1975 Am. J. Dis. Child. pmid:1080009
Hughes WT and Wan RT Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. 1967 Am. J. Dis. Child. pmid:4290285
Lascari AD et al. Varicella-like rash associated with Mycoplasma infection. 1974 Am. J. Dis. Child. pmid:4855375
Klugman KP et al. Clinical and nasopharyngeal isolates of unusual multiply resistant pneumococci. 1986 Am. J. Dis. Child. pmid:3766492
Halsey NA et al. Nosocomial pertussis: a failure of erythromycin treatment and prophylaxis. 1980 Am. J. Dis. Child. pmid:7377164
Noonan JA et al. Cerebral and cardiac complications from bacterial endocarditis. A successfully managed case with unusual complications. 1968 Am. J. Dis. Child. pmid:5303294
Bruhn FW Lyme disease. 1984 Am. J. Dis. Child. pmid:6711502
Bass JW et al. Susceptibility of Bordetella pertussis to nine antimicrobial agents. 1969 Am. J. Dis. Child. pmid:4303822