erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Pityriasis Rosea D017515 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Ross JI et al. Clinical resistance to erythromycin and clindamycin in cutaneous propionibacteria isolated from acne patients is associated with mutations in 23S rRNA. 1997 Antimicrob. Agents Chemother. pmid:9145890
Schülin T et al. In vitro activity of RU 64004, a new ketolide antibiotic, against gram-positive bacteria. 1997 Antimicrob. Agents Chemother. pmid:9145901
Kendall BJ et al. The effect of intravenous erythromycin on solid meal gastric emptying in patients with chronic symptomatic post-vagotomy-antrectomy gastroparesis. 1997 Aliment. Pharmacol. Ther. pmid:9146779
Barrett MS and Jones RN Antimicrobial activity and spectrum of sparfloxacin tested against erythromycin-resistant Streptococcus pneumoniae isolates. 1996 Diagn. Microbiol. Infect. Dis. pmid:9147907
Panhuyzen-Goedkoop NM and Crijns HJ [Iatrogenic collapse; can this be prevented?]. 1997 Ned Tijdschr Geneeskd pmid:9148161
Watts JL and Salmon SA Activity of selected antimicrobial agents against strains of Staphylococcus aureus isolated from bovine intramammary infections that produce beta-lactamase. 1997 J. Dairy Sci. pmid:9149974
Colburn WA et al. Pharmacokinetics of erythromycin on repetitive dosing. 1977 J Clin Pharmacol pmid:915023
McDonald PJ et al. Studies on absorption of a newly developed enteric-coated erythromycin base. 1977 J Clin Pharmacol pmid:915024
Ehrmann EH Infective endocarditis and practical guides for successful dentistry. 1997 Aust Dent J pmid:9153847
Lengyel C et al. [Erythrocyte-induced "torsade de pointes" ventricular tachycardia]. 1997 Orv Hetil pmid:9153994
Carroll KC et al. Susceptibility of beta-hemolytic streptococci to nine antimicrobial agents among four medical centers in Salt Lake City, Utah, USA. 1997 Diagn. Microbiol. Infect. Dis. pmid:9154408
Mitsuyama T et al. Inhibition by erythromycin of human pulmonary artery endothelial cell injury induced by human neutrophils. 1997 Respiration pmid:9154672
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Heaton MP and Handwerger S Conjugative mobilization of a vancomycin resistance plasmid by a putative Enterococcus faecium sex pheromone response plasmid. 1995 Microb. Drug Resist. pmid:9158753
Hessler PE et al. Isolation of isoflavones from soy-based fermentations of the erythromycin-producing bacterium Saccharopolyspora erythraea. 1997 Appl. Microbiol. Biotechnol. pmid:9163954
Sugihara E Effect of macrolide antibiotics on neutrophil function in human peripheral blood. 1997 Kansenshogaku Zasshi pmid:9164088
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Cheng CL et al. Steady-state pharmacokinetics of delavirdine in HIV-positive patients: effect on erythromycin breath test. 1997 Clin. Pharmacol. Ther. pmid:9164415
Lin JC and Quasny HA QT prolongation and development of torsades de pointes with the concomitant administration of oral erythromycin base and quinidine. 1997 May-Jun Pharmacotherapy pmid:9165570
Scalabrino G et al. Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord. 1997 Exp. Neurol. pmid:9168827
Somkuti GA et al. Molecular properties of the erythromycin resistance plasmid pPV141 from Staphylococcus chromogenes. 1997 Plasmid pmid:9169203
Leloup L et al. Single-crossover integration in the Lactobacillus sake chromosome and insertional inactivation of the ptsI and lacL genes. 1997 Appl. Environ. Microbiol. pmid:9172327
Koch B et al. Construction of specific erythromycin resistance mutations in the temperate lactococcal bacteriophage TP901-1 and their use in studies of phage biology. 1997 Appl. Environ. Microbiol. pmid:9172365
Piérard GE [Pharma Clinics. Drug of the month. Benzamycin, an up-date on topical treatment of acne]. 1997 Rev Med Liege pmid:9173479
Berg-Candolfi M et al. Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression. 1996 Xenobiotica pmid:9173679
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Rybak MJ et al. Pharmacodynamics of RP 59500 (quinupristin-dalfopristin) administered by intermittent versus continuous infusion against Staphylococcus aureus-infected fibrin-platelet clots in an in vitro infection model. 1997 Antimicrob. Agents Chemother. pmid:9174199
Young H et al. Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin. 1997 Int J STD AIDS pmid:9175650
Resnick J et al. Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. 1997 Am. J. Gastroenterol. pmid:9177505
Hofstetter A [Mycoplasma infections of the genito-urinary tract (author's transl)]. 1977 Schweiz. Rundsch. Med. Prax. pmid:918003
Roe DE et al. Mobile rRNA methylase genes coding for erythromycin resistance in Actinobacillus actinomycetemcomitans. 1996 J. Antimicrob. Chemother. pmid:9182102
Xia HX et al. Clarithromycin resistance in Helicobacter pylori: prevalence in untreated dyspeptic patients and stability in vitro. 1996 J. Antimicrob. Chemother. pmid:9182104
Roblin PM et al. In-vitro activity of dirithromycin against Chlamydia pneumoniae. 1997 J. Antimicrob. Chemother. pmid:9184366
Reines HD et al. Use of standard colon preparation in elective colectomy for carcinoma of the colon. 1977 Nov-Dec Rev Surg pmid:918536
Hanada E et al. Determination of erythromycin concentrations in rat plasma and liver by high-performance liquid chromatography with amperometric detection. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9188840
Huovinen P et al. The relationship between erythromycin consumption and resistance in Finland. Finnish Study Group for Antimicrobial Resistance. 1997 Ciba Found. Symp. pmid:9189633
Pacifico L et al. Ureaplasma urealyticum and pulmonary outcome in a neonatal intensive care population. 1997 Pediatr. Infect. Dis. J. pmid:9194108
Shimada T et al. Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans. 1997 Arch. Toxicol. pmid:9195021
Rendell DK and Callinan AP Comparison of erythromycin and oxytetracycline for the treatment of virulent footrot in grazing sheep. 1997 Aust. Vet. J. pmid:9196823
Baumüller A et al. [Bacterial prostatitis--therapeutic principles]. 1977 Z Urol Nephrol pmid:919805
Brückner R Gene replacement in Staphylococcus carnosus and Staphylococcus xylosus. 1997 FEMS Microbiol. Lett. pmid:9198277
Fons M et al. Isolation and characterization of a plasmid from Lactobacillus fermentum conferring erythromycin resistance. 1997 Plasmid pmid:9200223
Son R et al. Antibiotic resistance and plasmid profile of Aeromonas hydrophila isolates from cultured fish, Telapia (Telapia mossambica). 1997 Lett. Appl. Microbiol. pmid:9203404
Ishii M et al. Erythromycin derivative improves gastric emptying and insulin requirement in diabetic patients with gastroparesis. 1997 Diabetes Care pmid:9203450
Kabir I et al. Erythromycin and trimethoprim-sulphamethoxazole in the treatment of cholera in children. 1996 J Diarrhoeal Dis Res pmid:9203786
Caron D et al. Skin tolerance of adapalene 0.1% gel in combination with other topical antiacne treatments. 1997 J. Am. Acad. Dermatol. pmid:9204088
Rosser EJ German shepherd dog pyoderma: a prospective study of 12 dogs. 1997 Jul-Aug J Am Anim Hosp Assoc pmid:9204474
Monsieur I et al. Severe community-acquired pneumonia caused by atypical organisms. 1997 Acta Clin Belg pmid:9204587
Palacín C et al. In vitro anti-Helicobacter pylori activity of ebrotidine. 1997 Arzneimittelforschung pmid:9205746
Pacini N et al. Antimicrobial susceptibility tests on anaerobic oral mixed cultures in periodontal diseases. 1997 J. Clin. Periodontol. pmid:9205919