erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Stickney RH et al. Chlamydia trachomatis: a cause of an infantile pneumonia syndrome. 1978 AJR Am J Roentgenol pmid:101061
Simakova MG et al. [Clinical aspects, diagnosis and treatment of intrauterine infections]. 1995 Akush Ginekol (Mosk) pmid:7485765
Mezinova NN et al. [Effect of anti-chlamydial drugs on the effectiveness of the treatment of habitual abortion]. 1991 Akush Ginekol (Mosk) pmid:1951968
Mezinova NN and Chuchupalov PD [Endometrial Chlamydia infection in women with habitual abortion]. 1992 Akush Ginekol (Mosk) pmid:1476220
Kotua EN and Moroz AF [Erythromycin-ascorbinate therapy of pregnant rats with staphylococcal infections caused by staphylococcal strains both sensitive and resistant to erythromycin]. 1971 Akush Ginekol (Mosk) pmid:5138198
Kotua EN and Moroz AF [Passage of erythromycin and ristomycin into blood, placenta, fetus and amniotic fluid during various stages of pregnancy in generalized staphylococcal infection in albino rats]. 1971 Akush Ginekol (Mosk) pmid:4328638
Thornton JB and Harris JH The prevention of bacterial endocarditis. A new approach to a changing disease. 1986 Ala J Med Sci pmid:3953983
BOURICHON J [Importance of the suppository form in the administration of propionyl-erythromycin to children]. 1962 Alger Medicale pmid:13871918
LEBON J et al. [Staphylococcal diarrhea after terramycin administration; cure by erythromycin]. 1955 Alger Medicale pmid:14398597
Verhagen MA et al. Effects of a new motilide, ABT-229, on gastric emptying and postprandial antroduodenal motility in healthy volunteers. 1997 Aliment. Pharmacol. Ther. pmid:9663833
Talley NJ et al. Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. 2000 Aliment. Pharmacol. Ther. pmid:11121915
Emmanuel AV et al. Erythromycin for the treatment of chronic intestinal pseudo-obstruction: description of six cases with a positive response. 2004 Aliment. Pharmacol. Ther. pmid:15023171
McCallum RW and Cynshi O Clinical trial: effect of mitemcinal (a motilin agonist) on gastric emptying in patients with gastroparesis - a randomized, multicentre, placebo-controlled study. 2007 Aliment. Pharmacol. Ther. pmid:17894654
Winstead NS and Wilcox CM Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage: a cost-effectiveness analysis. 2007 Aliment. Pharmacol. Ther. pmid:17848180
Bell GD et al. Short report: omeprazole plus antibiotic combinations for the eradication of metronidazole-resistant Helicobacter pylori. 1992 Aliment. Pharmacol. Ther. pmid:1486161
Brand RM et al. Transdermal delivery of erythromycin lactobionate--implications for the therapy of gastroparesis. 1997 Aliment. Pharmacol. Ther. pmid:9218087
van Erpecum KJ et al. Review article: agents affecting gall-bladder motility--role in treatment and prevention of gallstones. 2000 Aliment. Pharmacol. Ther. pmid:10903008
Minocha A et al. Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. 1995 Aliment. Pharmacol. Ther. pmid:8580273
Osato MS et al. Comparative efficacy of new investigational agents against Helicobacter pylori. 2001 Aliment. Pharmacol. Ther. pmid:11284777
Kendall BJ et al. The effect of intravenous erythromycin on solid meal gastric emptying in patients with chronic symptomatic post-vagotomy-antrectomy gastroparesis. 1997 Aliment. Pharmacol. Ther. pmid:9146779